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High Pressure Injection Wound

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21. Conbercept Ophthalmic Injection for Patients With Macular Edema Caused by Branch Retinal Vein Occlusion

unhealed wounds, ulcers and fractures at present; Has systemically used corticosteroids (orally, intramuscularly, intravenously) within 6 months before screening; Has received systemic treatment with anti-VEGF agent(s) (e.g., bevacizumab) within 6 months before screening; Patients with any of the following abnormal laboratory tests Those who have hepatic, renal and immunologic dysfunction (this trial specifies that ALT and AST are twice as high as the ULN of this central laboratory, and that Crea (...) Conbercept Ophthalmic Injection for Patients With Macular Edema Caused by Branch Retinal Vein Occlusion Conbercept Ophthalmic Injection for Patients With Macular Edema Caused by Branch Retinal Vein Occlusion - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2017 Clinical Trials

22. Wound Repair

for hemostasis management See See Identify functional loss prior to injecting anesthesia Evaluate muscle and tendon structures Evaluate nerve structures See See Evaluate vascular structures Evaluate underlying bone IV. Imaging Indications suspected See Modalities XRay V. Contraindications: Relative Contraindications to primary wound closure Infected and inflamed wounds or Serious crush wounds Primary repair time constraints above not met VI. Indications: Surgical Consultation Deep hand or s Full-thickness (...) concentration Nose/Ears: 1:200,000 concentration XIII. Protocol: Irrigation Wear a mask with eye shield during irrigation Saline is as effective as antiseptics (e.g. 1% betadine) for irrigation Antseptics should be avoided inside the wound due to tissue injury Tap water is as safe and effective as saline for irrigation (and more plentiful) Moderate pressure irrigation is the key Irrigation with syringe provides approximately 5-8 psi Irrigate with minimum of 250 to 500 cc, or 50-100 ml/cm wound length (use

2018 FP Notebook

23. Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery

and maintained throughout surgery. The target is to maintain systolic blood pressure at 110 mmHg or higher. Other Name: Norepinephrine Active Comparator: Routine blood-pressure management Phenylephrine (25-50 ug) is injected or vasopressors is infused only when necessary. The target is to maintain systolic blood pressure at 90 mmHg or higher during surgery. Drug: Routine blood-pressure management Phenylephrine (25-50 ug) is injected or vasopressors is infused only when necessary. The target is to maintain (...) Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

24. Injecting Botulinum Toxin A Underneath the Skin to Treat Spinal Cord Pain in Patients With Spinal Cord Injury

not be neuropathic. Static Mechanical Allodynia testing [ Time Frame: up to 12 weeks post--injection ] Mechanical allodynia is a characteristic of evoked pain in subjects with neuropathic pain. Static allodynia to mechanical stimuli will be defined as a sensation of pain evoked by the pressure of the end of a wooden stick. The end of a wooden stick will touch the affected region with enough pressure to indent the skin, for 10 seconds. Afterwards, the subject will be asked to rate the perceived pain on an 11 (...) Injecting Botulinum Toxin A Underneath the Skin to Treat Spinal Cord Pain in Patients With Spinal Cord Injury Injecting Botulinum Toxin A Underneath the Skin to Treat Spinal Cord Pain in Patients With Spinal Cord Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2016 Clinical Trials

25. Effect of a Novel Intervention Using Daily Intermittent Hypoxia and High Intensity Training on Upper Limb Function in Individuals With Spinal Cord Injury

Intermittent Hypoxia (AIH), during first screening visit Participants do NOT have to stop taking antispasticity medications to participate in the study. Must be tested for anemia with a value of at least 10g/dl (for both men and women). Patients will be recommended to their primary care physician to correct anemia if low levels are detected Blood pressure must fall within this range- high: 160/110mmHg low: 85/55 mmHg Must be asymptomatic (no dizziness, lightheadedness, etc) Exclusion Criteria: Medical (...) Effect of a Novel Intervention Using Daily Intermittent Hypoxia and High Intensity Training on Upper Limb Function in Individuals With Spinal Cord Injury Effect of a Novel Intervention Using Daily Intermittent Hypoxia and High Intensity Training on Upper Limb Function in Individuals With Spinal Cord Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail

2018 Clinical Trials

26. High Intensity Exercise in Incomplete SCI

High Intensity Exercise in Incomplete SCI High Intensity Exercise in Incomplete SCI - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. High Intensity Exercise in Incomplete SCI The safety and scientific (...) Information provided by (Responsible Party): George Hornby, Indiana University Study Details Study Description Go to Brief Summary: The goal of this study is to identify the comparative efficacy of high-intensity walking training in individuals with chronic, motor incomplete spinal cord injury as compared to lower-intensity walking exercise. Condition or disease Intervention/treatment Phase Spinal Cord Injuries Procedure: Walking training Not Applicable Detailed Description: Background/Readiness

2018 Clinical Trials

27. Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Prostatic Adenocarcinoma

Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Prostatic Adenocarcinoma Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Metastatic Prostatic Adenocarcinoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Metastatic Prostatic Adenocarcinoma The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2018 Clinical Trials

28. Pressure Device in the Treatment of Ear Keloids

. Patients either undergo surgery using the "fillet technique" and intra-lesional injections of triamcinolone 10mg /ml every 4 to 6 weeks for 6 months, or they are additionally treated with a non-customized pressure device. Condition or disease Intervention/treatment Phase Keloid Ear Device: Pressure Device Procedure: Fillet Technique Drug: Triamcinolone Not Applicable Detailed Description: The prospective randomized controlled trial will be conducted at the Department of Otorhinolaryngology, Head (...) or magnifying glasses. The keloid is "peeled" out of the excessive skin pocket. If necessary skin trimming is performed and non-resorbable monofilament single sutures are placed. The first intracutaneous injection of triamcinolone 10mg/ml is given before wound dressing is placed. A blanching of the lesion marks the endpoint of injection. Cutaneous sutures are removed after approximately 7 days. Injection of triamcinolone is repeated every 4 to 6 weeks for a total of 6 months. When removing the sutures

2016 Clinical Trials

29. Transpulmonary Pressure Gradients in High Frequency Oscillation

Transpulmonary Pressure Gradients in High Frequency Oscillation Transpulmonary Pressure Gradients in High Frequency Oscillation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Transpulmonary Pressure (...) of British Columbia Study Details Study Description Go to Brief Summary: Patients with severe lung conditions occasionally require support with a special ventilator (breathing machine) called the High Frequency Oscillator (HFO). Effective ventilation requires that the pressure generated by the ventilator be as high as possible but not too high as this can damage the lungs. In patients on HFO, there is not a well defined way to measure this pressure. We will insert a small probe into the esophagus

2011 Clinical Trials

30. Best practices for injections and related procedures toolkit

-stick or other puncture wounds caused by sharp objects. Needles, scalpels and other sharps should be handled with extreme caution. Note: This table provides information on glove use in relation to any type of injection. A table on glove use in general health-care settings is given in Annex A. 2.1.3 Other single-use personal protective equipment Masks, eye protection and other protective clothing ARE NOT indicated for the injection procedures covered by this document unless exposure to blood splashes (...) for injection 9 2.2.2 Medication Types of medication containers and recommendations on their use are given in Table 2.5. T able 2.5 Recommendations on medication containers Type of container Recommendations Reason Single-dose vial Preferred Low likelihood of contamination Multiple-dose vial Only if unavoidable High likelihood of contamination if aseptic technique is poor Ampoules Pop-open preferred Breaking a glass ampoule may result in particulate matter escaping from the vial, it may also injure

2010 World Health Organisation Guidelines

31. Wound Healing, Widened and Hypertrophic Scars

in inflammation. Int Rev Connect Tissue Res . 1964. 2:301-25. . Stewart RJ, Duley JA, Dewdney J, et al. The wound fibroblast and macrophage. II: Their origin studied in a human after bone marrow transplantation. Br J Surg . 1981 Feb. 68(2):129-31. . Ahn ST, Monafo WW, Mustoe TA. Topical silicone gel for the prevention and treatment of hypertrophic scar. Arch Surg . 1991 Apr. 126(4):499-504. . Sharp PA, Pan B, Yakuboff KP, Rothchild D. Development of a Best Evidence Statement for the Use of Pressure Therapy (...) /keloid scarring. Int J Oral Maxillofac Surg . 1994 Aug. 23(4):232-6. . Media Gallery This patient's neck wound developed a hypertrophic scar. It was revised with a fusiform excision and an intraoperative triamcinolone (Kenalog) injection. Postoperatively, the patient used silicone gel daily for 6 months and obtained a very satisfactory result. This patient underwent revision of her widened scar with a Millard 2-flap technique. The fusiform was incised around the deepithelialized scar. The wound edges

2014 eMedicine Surgery

32. Wound Healing, Keloids

. The most frequently involved sites of keloids are areas of the body that are constantly subjected to high skin tension. Wounds on the anterior chest, shoulders, flexor surfaces of the extremities (eg, deltoid region), and anterior neck and wounds that cross skin tension lines are more susceptible to abnormal scar formation. The most important risk factor for the development of abnormal scars such as keloids is a wound healing by secondary intention, especially if healing time is greater than 3 weeks (...) in the treatment of keloids. The sheets can be worn for as long as 24 h/d for up to 1 year, with care to avoid contact dermatitis and skin breakdown. The silicone does not appear to enter the skin; therefore, the antikeloid effects appear to be secondary to both occlusion and hydration. Studies have demonstrated that silicone gel increases the temperature of the scar, possibly increasing collagenase activity. Increased pressure, hydration of the stratum corneum, and direct pressure on the wound also may

2014 eMedicine Surgery

33. Wound Closure Technique

and will destroy inflammatory cells. Simple wound care with sterile water or saline should be used. If necessary, a syringe and intravenous catheter can be used to pressure wash contaminants from dirty wounds. Epithelialization and neovascularization (occurring within the overlap of proliferation and maturation phases) result from the increase in cellular activity. Stromal elements in the form of extracellular matrix materials are secreted and organized. This new tissue, called granulation tissue, depends (...) a strong flexible bond. In some forms, it can induce a substantial inflammatory reaction if implanted subcutaneously. If used superficially on the epidermal surface, few problems with inflammation occur. In a study on the use of adhesives in the emergency department, adhesives were more likely to be used in facial lacerations and in children and less likely to be used in longer wounds. [ ] The concomitant use of either a topical anesthetic or no anesthetic, as opposed to an injectable, was cited

2014 eMedicine Surgery

34. Wound Care (Overview)

, Skintact, Release, Tegaderm, Bioclusive Transparent films are highly conformable acrylic adhesive films with no absorptive capacity and little hydrating ability. They may be vapor permeable or perforated. These dressings are useful for clean, dry wounds with minimal exudate. They also are used to secure an underlying absorptive material, to protect high-friction areas and areas that are difficult to bandage (eg, heels) and to secure intravenous catheters. Table 2. Staging Pressure Ulcers Stage (...) , FACS, FCCP, CNSC; Chief Editor: Zubin J Panthaki, MD, CM, FACS, FRCSC Share Email Print Feedback Close Sections Sections Wound Care Overview Background This article discusses the management of chronic wounds. This topic is naturally diverse and far-reaching. Wound care in general and in terms of specific etiologies is considered. The images below depict a sacral pressure ulcer. Image of advanced sacral pressure ulcer shows the effects of pressure, shearing, and moisture. Next: Epidemiology

2014 eMedicine Surgery

35. Wound Care (Diagnosis)

, Skintact, Release, Tegaderm, Bioclusive Transparent films are highly conformable acrylic adhesive films with no absorptive capacity and little hydrating ability. They may be vapor permeable or perforated. These dressings are useful for clean, dry wounds with minimal exudate. They also are used to secure an underlying absorptive material, to protect high-friction areas and areas that are difficult to bandage (eg, heels) and to secure intravenous catheters. Table 2. Staging Pressure Ulcers Stage (...) , MBA, FACS, FCCP, CNSC; Chief Editor: Zubin J Panthaki, MD, CM, FACS, FRCSC Share Email Print Feedback Close Sections Sections Wound Care Overview Background This article discusses the management of chronic wounds. This topic is naturally diverse and far-reaching. Wound care in general and in terms of specific etiologies is considered. The images below depict a sacral pressure ulcer. Image of advanced sacral pressure ulcer shows the effects of pressure, shearing, and moisture. Next: Epidemiology

2014 eMedicine Surgery

36. Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia

Life expectancy < 6 months Patient determined to be nonsurgical candidate due to reasons such as High-risk medical conditions Unstable cardiac disease Stroke or transient ischemic attack leading to limitations in lower extremities or occurring within 180 days prior to the initial screening visit Severe arthritis or other musculoskeletal disorder. Systolic blood pressure (supine) ≤ 90 mmHg Resting heart rate > 100 bpm Poorly controlled diabetes mellitus (HgbA1c > 10%) Life‐threatening complications (...) Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached

2014 Clinical Trials

37. Therapeutic Injections for Pain Management (Treatment)

reactions to LAs can result from high blood levels of the drug due to accidental intravenous (IV) infusion of all or part of the therapeutic dose, injection of an excessive amount of drug, or abnormal rates of absorption and biotransformation of the drug. Typically, these reactions demonstrate a combination of cardiovascular, respiratory, and central nervous system side effects that range from mild to severe. Mild reactions occur when systemic blood levels of LA rise above the usual physiologic levels (...) complications may result from systemic reactions or be due to specific procedures. For example, injuries to peripheral nerves may result from direct trauma including localized hematoma, compression by tourniquet, unintentional neural traction, compression due to positioning, or injection of an excessively high concentration of LA. Complications following subarachnoid or epidural injections can result from direct spinal cord or nerve root trauma, spinal cord compression by hematoma, or spinal cord ischemia

2014 eMedicine.com

38. Therapeutic Injections for Pain Management (Overview)

reactions to LAs can result from high blood levels of the drug due to accidental intravenous (IV) infusion of all or part of the therapeutic dose, injection of an excessive amount of drug, or abnormal rates of absorption and biotransformation of the drug. Typically, these reactions demonstrate a combination of cardiovascular, respiratory, and central nervous system side effects that range from mild to severe. Mild reactions occur when systemic blood levels of LA rise above the usual physiologic levels (...) complications may result from systemic reactions or be due to specific procedures. For example, injuries to peripheral nerves may result from direct trauma including localized hematoma, compression by tourniquet, unintentional neural traction, compression due to positioning, or injection of an excessively high concentration of LA. Complications following subarachnoid or epidural injections can result from direct spinal cord or nerve root trauma, spinal cord compression by hematoma, or spinal cord ischemia

2014 eMedicine.com

39. Therapeutic Injections for Pain Management (Follow-up)

reactions to LAs can result from high blood levels of the drug due to accidental intravenous (IV) infusion of all or part of the therapeutic dose, injection of an excessive amount of drug, or abnormal rates of absorption and biotransformation of the drug. Typically, these reactions demonstrate a combination of cardiovascular, respiratory, and central nervous system side effects that range from mild to severe. Mild reactions occur when systemic blood levels of LA rise above the usual physiologic levels (...) complications may result from systemic reactions or be due to specific procedures. For example, injuries to peripheral nerves may result from direct trauma including localized hematoma, compression by tourniquet, unintentional neural traction, compression due to positioning, or injection of an excessively high concentration of LA. Complications following subarachnoid or epidural injections can result from direct spinal cord or nerve root trauma, spinal cord compression by hematoma, or spinal cord ischemia

2014 eMedicine.com

40. Therapeutic Injections for Pain Management (Diagnosis)

reactions to LAs can result from high blood levels of the drug due to accidental intravenous (IV) infusion of all or part of the therapeutic dose, injection of an excessive amount of drug, or abnormal rates of absorption and biotransformation of the drug. Typically, these reactions demonstrate a combination of cardiovascular, respiratory, and central nervous system side effects that range from mild to severe. Mild reactions occur when systemic blood levels of LA rise above the usual physiologic levels (...) complications may result from systemic reactions or be due to specific procedures. For example, injuries to peripheral nerves may result from direct trauma including localized hematoma, compression by tourniquet, unintentional neural traction, compression due to positioning, or injection of an excessively high concentration of LA. Complications following subarachnoid or epidural injections can result from direct spinal cord or nerve root trauma, spinal cord compression by hematoma, or spinal cord ischemia

2014 eMedicine.com

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