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Herpes Simplex Keratitis

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121. Herpes Simplex (Overview)

Treatment of Herpes Simplex Keratitis?. Ann Emerg Med . 2016 Jul. 68 (1):26-7. . Pasternak B, Hviid A. Use of acyclovir, valacyclovir, and famciclovir in the first trimester of pregnancy and the risk of birth defects. JAMA . 2010 Aug 25. 304(8):859-66. . Kaminester LH, Pariser RJ, Pariser DM, Weiss JS, Shavin JS, Landsman L, et al. A double-blind, placebo-controlled study of topical tetracaine in the treatment of herpes labialis. J Am Acad Dermatol . 1999 Dec. 41 (6):996-1001. . [Guideline] Workowski KA (...) Herpes Simplex (Overview) Herpes Simplex in Emergency Medicine: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvNzgzMTEzLW92ZXJ2aWV3 processing > Herpes Simplex

2014 eMedicine Emergency Medicine

122. Herpes Simplex Encephalitis (Overview)

. Like other forms of , herpes simplex meningitis usually has a benign course and is not discussed in this article. Patients with HSV may require long-term antiviral treatment if they have recurrent lesions or if other organ systems are involved (as in herpes simplex keratitis). HSV remains dormant in the nervous system; rarely, it presents as encephalitis, possibly by direct transmission through peripheral nerves to the central nervous system (CNS). This encephalitis is a neurologic emergency (...) Herpes Simplex Encephalitis (Overview) Herpes Simplex Encephalitis: Practice Essentials, Background, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTE2NTE4My1vdmVydmlldw== processing > Herpes

2014 eMedicine Emergency Medicine

123. Neuroprotectin D1 reduces the severity of herpes simplex virus induced corneal immunopathology. Full Text available with Trip Pro

Neuroprotectin D1 reduces the severity of herpes simplex virus induced corneal immunopathology. Neuroprotectin D1 (NPD1) is an anti-inflammatory and proresolving lipid mediator biosynthesized from the omega-3-polyunsaturated fatty acid docosahexaenoic acid (DHA). The purpose of this study is to test the therapeutic potential of NPD1 for the treatment of herpes simplex virus (HSV)-induced stromal keratitis (SK) using a mouse model.C57BL/6 mice were infected ocularly with HSV-1 strain RE

2013 Investigative Ophthalmology & Visual Science

124. Foreign body mimicking a herpes simplex dendritic ulcer in the cornea Full Text available with Trip Pro

Foreign body mimicking a herpes simplex dendritic ulcer in the cornea 23843417 2014 03 10 2016 05 19 1757-790X 2013 2013 Jul 09 BMJ case reports BMJ Case Rep Foreign body mimicking a herpes simplex dendritic ulcer in the cornea. 10.1136/bcr-2013-200143 bcr2013200143 Yeo Damien Chia Ming DC Department of Ophthalmology, Singleton Hospital, Swansea, UK. cm.yeo@doctors.org.uk eng Case Reports Journal Article 2013 07 09 England BMJ Case Rep 101526291 1757-790X IM Corneal Ulcer diagnosis virology (...) Diagnosis, Differential Eye Foreign Bodies diagnosis Female Humans Keratitis, Herpetic diagnosis Middle Aged 2013 7 12 6 0 2013 7 12 6 0 2014 3 13 6 0 epublish 23843417 bcr-2013-200143 10.1136/bcr-2013-200143 PMC3736634

2013 BMJ case reports

125. Herpes Simplex Keratitis

Herpes Simplex Keratitis Herpes Simplex Keratitis - Eye Disorders - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / IN THIS TOPIC OTHER TOPICS IN THIS CHAPTER Test your knowledge Blurred Vision (...) SOCIAL MEDIA Add to Any Platform Loading , MD, FACS, Sidney Kimmel Medical College at Thomas Jefferson University Click here for Patient Education NOTE: This is the Professional Version. CONSUMERS: Topic Resources Herpes simplex keratitis is corneal infection with herpes simplex virus. It may involve the iris. Symptoms and signs include foreign body sensation, lacrimation, photophobia, and conjunctival hyperemia. Recurrences are common and may lead to corneal hypoesthesia, ulceration, permanent

2013 Merck Manual (19th Edition)

126. Secretory Immunoglobulin A and Herpes Keratitis Full Text available with Trip Pro

Secretory Immunoglobulin A and Herpes Keratitis The sensitization of herpes simplex virus by immunoglobulin G (IgG) antibodies was studied. Although herpes simplex virus sensitized by IgG could not be neutralized by IgA antibodies known to neutralize a similar number of unsensitized viruses, this protection could be overcome by larger amounts of IgA antibodies. This suggests that the effective neutralization of herpes simplex virus in ocular tissue is dependent on the relative concentrations (...) of IgA and IgG antibodies. In vivo sensitized virus was isolated from chronically infected animals, and this may be the mechanism by which herpes simplex virus persists in animals with high titers of circulating antibodies in their serum.

1970 Infection and immunity

127. Immunity to Ocular and Genital Herpes Simplex Viruses Infections Full Text available with Trip Pro

Immunity to Ocular and Genital Herpes Simplex Viruses Infections 23326289 2013 08 12 2016 10 25 1740-2530 2012 2012 Clinical & developmental immunology Clin. Dev. Immunol. Immunity to ocular and genital herpes simplex viruses infections. 732546 10.1155/2012/732546 Chentoufi Aziz Alami AA BenMohamed Lbachir L Van De Perre Philippe P Ashkar Ali A AA eng R01 EY014900 EY NEI NIH HHS United States R01 EY019896 EY NEI NIH HHS United States Editorial 2012 12 26 Egypt Clin Dev Immunol 101183692 1740 (...) -2522 IM Animals Herpes Genitalis genetics immunology metabolism virology Humans Immunity immunology Keratitis, Herpetic genetics immunology metabolism virology Mice Simplexvirus immunology 2012 11 20 2012 11 20 2013 1 18 6 0 2013 1 18 6 0 2013 8 13 6 0 ppublish 23326289 10.1155/2012/732546 PMC3541643

2012 Clinical and Developmental Immunology

128. Role of miR-132 in Angiogenesis after Ocular Infection with Herpes Simplex Virus Full Text available with Trip Pro

Role of miR-132 in Angiogenesis after Ocular Infection with Herpes Simplex Virus MicroRNAs (miRNAs) are small regulatory molecules that control diverse biological processes that include angiogenesis. Herpes simplex virus (HSV) causes a chronic immuno-inflammatory response in the eye that may result in corneal neovascularization during blinding immunopathological lesion stromal keratitis (SK). miR-132 is a highly conserved miRNA that is induced in endothelial cells in response to growth factors

2012 The American journal of pathology

129. Experimental and Clinical Use of Aureomycin in Herpes Simplex Full Text available with Trip Pro

Experimental and Clinical Use of Aureomycin in Herpes Simplex 15418604 2004 09 30 2018 12 01 0065-9533 47 1949 Transactions of the American Ophthalmological Society Trans Am Ophthalmol Soc Experimental and clinical use of aureomycin in herpes simplex. 335-48 BRALEY A E AE ALEXANDER R C RC eng Journal Article United States Trans Am Ophthalmol Soc 7506106 0065-9533 WCK1KIQ23Q Chlortetracycline OM Chlortetracycline Cornea Herpes Simplex Keratitis 5019:8463:18:56:130 AUREOMYCIN CORNEA KERATITIS

1949 Transactions of the American Ophthalmological Society

130. Phosphonoacetic Acid in the Treatment of Experimental Ocular Herpes Simplex Infections Full Text available with Trip Pro

Phosphonoacetic Acid in the Treatment of Experimental Ocular Herpes Simplex Infections Phosphonoacetic acid had a significant antiviral effect when applied topically, both in liquid and ointment preparations, on superficial herpetic keratitis in rabbits and was equally as effective as idoxuridine. It was also effective in the treatment of idoxuridine-resistant herpetic keratitis. Phosphonoacetic acid was not effective in the treatment of experimental herpetic iritis when applied topically

1976 Antimicrobial Agents and Chemotherapy

131. Hydroxyquinolines Inhibit Ribonucleic Acid-Dependent Deoxyribonucleic Acid Polymerase and Inactivate Rous Sarcoma Virus and Herpes Simplex Virus Full Text available with Trip Pro

" was observed with high concentrations of drug, causing less inhibition of deoxyribonucleic acid synthesis than was observed with lower concentrations. Herpes simplex virus type 1 was inactivated also by the 8-hydroxyquinolines and their copper complexes. No intracellular inhibition of plaque formation was observed. Treatment with 8-hydroxyquinoline sulfate had no effect on the resolution of herpetic keratitis in rabbits. Some 8-hydroxyquinolines bind to deoxyribonucleic acid in the presence of copper (...) Hydroxyquinolines Inhibit Ribonucleic Acid-Dependent Deoxyribonucleic Acid Polymerase and Inactivate Rous Sarcoma Virus and Herpes Simplex Virus 8-Hydroxyquinoline and several of its derivatives inactivate the transforming ability of Rous sarcoma virus and inhibit its ribonucleic acid-dependent deoxyribonucleic acid polymerase activity. The copper complex of these metal-binding ligands is as active as the free ligand. The activity of the 8-hydroxyquinolines is approximately 50-fold more

1976 Antimicrobial Agents and Chemotherapy

132. Herpes simplex and zoster. Full Text available with Trip Pro

Diseases, Male Herpes Simplex congenital drug therapy immunology Herpes Zoster drug therapy Humans Idoxuridine therapeutic use Immunologic Deficiency Syndromes complications Infant, Newborn Infant, Newborn, Diseases Keratitis, Dendritic Male Simplexvirus Steroids adverse effects Stomatitis 1973 2 17 1973 2 17 0 1 1973 2 17 0 0 ppublish 4347938 PMC1588333 Br Med J. 1964 Oct 17;2(5415):987-8 14185689 N Engl J Med. 1959 May 21;260(21):1062-5 13657339 J R Coll Gen Pract. 1970 Dec;20(101):323-7 5533234 J (...) Herpes simplex and zoster. 4347938 1973 05 04 2018 11 13 0007-1447 1 5850 1973 Feb 17 British medical journal Br Med J Herpes simplex and zoster. 406-10 Juel-Jensen B E BE eng Journal Article England Br Med J 0372673 0007-1447 0 Steroids 04079A1RDZ Cytarabine LGP81V5245 Idoxuridine YOW8V9698H Dimethyl Sulfoxide AIM IM Age Factors Central Nervous System Diseases Conjunctivitis Cytarabine therapeutic use Dimethyl Sulfoxide therapeutic use Eczema Female Fingers Genital Diseases, Female Genital

1973 British medical journal

133. Acute follicular conjunctivitis and keratoconjunctivitis due to herpes simplex virus in London. Full Text available with Trip Pro

of antiherpes simplex virus antibody in their blood. No adenovirus was isolated from these patients, but complement fixation test for adenovirus was positive in 1 patient with cultural test positive for herpes simplex virus. Most patients were between 20 and 35 years old and the ratio of males to females was 12 to 13. At the initial visit the clinical features of disease were moderate to severe conjunctival papillary and follicular reasons with epithelial and subepithelial punctate keratitis but little (...) Acute follicular conjunctivitis and keratoconjunctivitis due to herpes simplex virus in London. During the 18 months January 1975 to June 1976, 25 cases of acute herpetic follicular conjunctivitis and keratoconjunctivitis resembling adenovirus ocular infection presented in the External Eye Disease Clinic, Moorfields Eye Hospital, City Road, London. Herpes simplex virus was isolated in HEp2 cells in 22 patients, and the remaining 3 patients were identified by a minimum 4-fold rise in the level

1978 The British journal of ophthalmology

134. Corneal hypersensitivity to herpes simplex. Full Text available with Trip Pro

Corneal hypersensitivity to herpes simplex. 4295044 1968 03 24 2018 11 13 0007-1161 51 12 1967 Dec The British journal of ophthalmology Br J Ophthalmol Corneal hypersensitivity to herpes simplex. 843-6 Swyers J S JS Lausch R N RN Kaufman H E HE eng Journal Article England Br J Ophthalmol 0421041 0007-1161 0 Antigens IM Animals Antigens Chick Embryo Cornea Edema complications Guinea Pigs Hypersensitivity, Delayed complications Keratitis, Dendritic etiology Simplexvirus immunology 1967 12 1 1967

1967 The British journal of ophthalmology

135. Management of ocular herpes simplex. Full Text available with Trip Pro

Management of ocular herpes simplex. 6029236 1967 09 12 2013 11 21 0007-1161 51 7 1967 Jul The British journal of ophthalmology Br J Ophthalmol Management of ocular herpes simplex. 494-5 Patterson A A eng Journal Article England Br J Ophthalmol 0421041 0007-1161 0 Mydriatics 0 Steroids LGP81V5245 Idoxuridine IM Bandages Cautery Humans Idoxuridine therapeutic use Keratitis, Dendritic therapy Mydriatics therapeutic use Steroids therapeutic use 1967 7 1 1967 7 1 0 1 1967 7 1 0 0 ppublish 6029236

1967 The British journal of ophthalmology

136. Herpes Simplex Uveitis: A Clinical and Experimental Study Full Text available with Trip Pro

Herpes Simplex Uveitis: A Clinical and Experimental Study 14032779 1998 11 01 2018 12 01 0065-9533 60 1962 Transactions of the American Ophthalmological Society Trans Am Ophthalmol Soc Herpes simplex uveitis: a clinical and experimental study. 440-70 KIMURA S J SJ eng Journal Article United States Trans Am Ophthalmol Soc 7506106 0065-9533 OM Herpes Simplex Humans Keratitis Keratitis, Dendritic Uveitis HERPES SIMPLEX KERATITIS, DENDRITIC UVEITIS 1962 1 1 1962 1 1 0 1 1962 1 1 0 0 ppublish

1962 Transactions of the American Ophthalmological Society

137. VARIANTS OF HERPES SIMPLEX VIRUS: ISOLATION, CHARACTERIZATION, AND FACTORS INFLUENCING PLAQUE FORMATION Full Text available with Trip Pro

VARIANTS OF HERPES SIMPLEX VIRUS: ISOLATION, CHARACTERIZATION, AND FACTORS INFLUENCING PLAQUE FORMATION Rapp, Fred (Baylor University College of Medicine, Houston, Tex.). Variants of herpes simplex virus: isolation, characterization, and factors influencing plaque formation. J. Bacteriol. 86:985-991. 1963.-Variants of herpes simplex virus were isolated which differed in plaque size and in virulence for rabbits and mice. Keratitis on the rabbit cornea and generalized disease were associated

1963 Journal of bacteriology

138. Clinical evaluation of adenine arabinoside and idoxuridine in the treatment of ocular herpes simplex. (Abstract)

Clinical evaluation of adenine arabinoside and idoxuridine in the treatment of ocular herpes simplex. A Double-blind clinical study comparing idoxuridine (IDU) with adenine arabinoside (ara-A) in treating 54 routine herpetic ulcers, and an open ara-A therapy study of 58 herpetic ulcers in patients intolerant of or resistant to IDU, was carried out over a four-year period. There was no significant difference in healing time between IDU-treated eyes (11.5 days) and ara-A-treated eyes (12.4 days (...) and one was dropped from the study because his initial disease could not be distinguished from severe IDU-induced keratitis.

1975 American journal of ophthalmology Controlled trial quality: uncertain

139. Clinical evaluation of deep anterior lamellar keratoplasty using glycerol-cryopreserved corneal tissues for refractory herpetic stromal keratitis: An observational study. Full Text available with Trip Pro

Clinical evaluation of deep anterior lamellar keratoplasty using glycerol-cryopreserved corneal tissues for refractory herpetic stromal keratitis: An observational study. The study aimed to evaluate the therapeutic effects of deep anterior lamellar keratoplasty (DALK) using glycerol-cryopreserved corneal tissues (GCCTs) in patients with refractive herpes simplex keratitis (HSK). This article was a retrospective, noncomparative, and interventional case series. Patients with HSK underwent DALK

2016 Medicine

140. Clinical and corneal microbial profile of infectious keratitis in a high HIV prevalence setting in rural South Africa Full Text available with Trip Pro

hospitals in rural South Africa. Corneal swabs were tested for herpes simplex virus type 1 (HSV-1) and 2 (HSV-2), varicella zoster virus (VZV) and adenovirus DNA by real-time polymerase chain reaction (PCR) and for bacteria and fungi by culture. Based on clinical history, disease characteristics and laboratory results, 29 (63 %) patients were diagnosed as viral keratitis, including 14 (48 %) viral keratitis cases complicated by bacterial superinfection, and 17 (37 %) as bacterial keratitis. VZV and HSV (...) -1 DNA was detected in 11 (24 %) and 5 (11 %) corneal swabs, respectively. Among clinically defined viral keratitis cases, a negative viral swab was predominantly (93 %) observed in cases with subepithelial inflammation and was significantly associated with an increased duration of symptoms (p = 0.003). The majority of bacteria cultured were Gram-positive (24/35), including Staphylococcus epidermidis and S. aureus. Viral aetiology was significantly associated with a history of herpes zoster

2016 European Journal of Clinical Microbiology & Infectious Diseases

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