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Herpangina

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2. High prevalence of coxsackievirus A2 in children with herpangina in Thailand in 2015 (PubMed)

High prevalence of coxsackievirus A2 in children with herpangina in Thailand in 2015 Coxsackievirus (CV) is a member of the genus Enterovirus and the family Picornaviridae. CV infection can cause herpangina, a disease characterized by multiple ulcers on the tonsils and soft palate affecting mostly young children. CV strains are categorized by serotypes. Unfortunately, serotypes responsible for infections in patients are often undetermined. This knowledge gap partly contributes (...) to the ineffective prevention and control of CV-associated herpangina in Southeast Asia. To characterize the viral etiology of children presented with herpangina, 295 throat swabs were tested for human enterovirus infection. Using RT-PCR specific for the viral 5'UTR/VP2 and the VP1 regions, two most frequent CV types found in these samples were CV-A2 (33.33%, 40/120) and CV-A4 (15.8%, 19/120). Phylogenetic analysis of the VP1 gene demonstrated that the CV-A2 strains in this study not only were closely related

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2017 Virusdisease

3. Comparison of Nonpolio Enteroviruses in Children With Herpangina and With Hand, Foot and Mouth Disease in Taiwan. (PubMed)

Comparison of Nonpolio Enteroviruses in Children With Herpangina and With Hand, Foot and Mouth Disease in Taiwan. Nonpolio enterovirus (NPEV) infections are often present with herpangina (HA) and hand, foot and mouth disease (HFMD). Most countries sample NPEVs in HFMD cases, targeting enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) that are associated with outbreaks and severe complications. HA is also monitored in Taiwan and several other countries, but its viral characteristics

2019 Pediatric Infectious Dsease Journal

4. Hand, foot and mouth disease and herpangina caused by enterovirus A71 infections: a review of enterovirus A71 molecular epidemiology, pathogenesis, and current vaccine development (PubMed)

Hand, foot and mouth disease and herpangina caused by enterovirus A71 infections: a review of enterovirus A71 molecular epidemiology, pathogenesis, and current vaccine development Enterovirus A71 (EV-A71) infections are one of the main etiological agents of hand, foot and mouth disease (HFMD) and herpangina worldwide. EV-A71 infection is a life-threatening communicable disease and there is an urgent global need for the development of vaccines for its prevention and control. The morbidity rate

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2018 Revista do Instituto de Medicina Tropical de São Paulo

5. Effect of Recombinant Human Interferon α-2b Spray on Herpangina

Effect of Recombinant Human Interferon α-2b Spray on Herpangina Effect of Recombinant Human Interferon α-2b Spray on Herpangina - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect of Recombinant Human (...) Interferon α-2b Spray on Herpangina The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03266601 Recruitment Status : Completed First Posted : August 30, 2017 Last Update Posted : March 7, 2019 Sponsor: Children's Hospital of Fudan University Collaborators: Tianjin Sinobioway Biomedicine Co.Ltd. Hunan

2017 Clinical Trials

6. Large outbreak of herpangina in children caused by enterovirus in summer of 2015 in Hangzhou, China (PubMed)

Large outbreak of herpangina in children caused by enterovirus in summer of 2015 in Hangzhou, China Herpangina, usually caused by coxsackie virus A, is prevalent in children spreading through the fecal-oral transmission and the respiratory droplets dissemination. Also, it is mostly asymptomatic and self-limiting. In our study, we found that large outbreak of herpangina in children occurred in the summer of 2015 in Hangzhou, China. From May 1th to August 31th, a total of 10 210 children were (...) diagnosed with herpangina in Children's Hospital of Zhejiang University School of Medicine. 2 310 throat swabs were collected and tested for enterovirus detection by real-time RT-PCR, while 1 651 cases were positive with the rate of 71.5%. Based on VP1 gene or 5'UTR region sequences, Coxsackievirus A2, A4, A6, A10, B2, B4 and echovirus 30 were detected in these cases. More importantly, Coxsackievirus A2 may be the major subtype of enterovirus resulting in children with herpangina in hangzhou, China.

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2016 Scientific reports

7. Epidemiological and etiological characteristics of herpangina and hand foot mouth diseases in Jiangsu, China, 2013–2014 (PubMed)

Epidemiological and etiological characteristics of herpangina and hand foot mouth diseases in Jiangsu, China, 2013–2014 Herpangina (HA) and hand, foot, and mouth disease (HFMD) are common infectious diseases caused by human enteroviruses and frequently occurr in young children. Previous published studies have mainly focused on HFMD, while the HA epidemiological and etiological characteristics in mainland China have not been described. From June, 2013 to March, 2014, HA and HFMD patients were

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2016 Human vaccines & immunotherapeutics

8. Enterovirus-related diarrhoea in Guangdong, China: clinical features and implications in hand, foot and mouth disease and herpangina. (PubMed)

Enterovirus-related diarrhoea in Guangdong, China: clinical features and implications in hand, foot and mouth disease and herpangina. A series of complications caused by enteroviruses, including meningitis, encephalitis, acute flaccid paralysis, acute cardiopulmonary failure, respiratory infection, and myocardial injury have been reported in hand, foot and mouth disease/herpangina (HFMD/HA). However, the complication of diarrhoea caused by enteroviruses has been neglected, and a summary of its

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2016 BMC Infectious Diseases

9. Herpangina

Herpangina Herpangina Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Herpangina Herpangina Aka: Herpangina From Related Chapters II (...) . Epidemiology Occurs in summer months (may be epidemic) III. Etiology Coxsackie Echovirus IV. Symptoms V. Signs Non-toxic appearance Multiple small 1-2 mm or ulcers , posterior pharynx and s Spares the anterior pharynx Contrast which spares the posterior pharynx No skin lesions Unlike VI. Differential Diagnosis s in anterior pharynx, sparing posterior pharynx External s are only seen with HSV (not with Herpangina or ) Images: Related links to external sites (from Bing) These images are a random sampling

2018 FP Notebook

10. PREVALENCE OF HUMAN ENTEROVIRUS AMONG PATIENTS WITH HAND, FOOT, AND MOUTH DISEASE AND HERPANGINA IN THAILAND, 2013. (PubMed)

PREVALENCE OF HUMAN ENTEROVIRUS AMONG PATIENTS WITH HAND, FOOT, AND MOUTH DISEASE AND HERPANGINA IN THAILAND, 2013. Human enterovirus (EV) infection causes hand, foot, and mouth disease (HFMD) and herpangina (HA). We studied the prevalence of enterovirus (EV) among patients with HFMD and HA in Thailand during 2013. We conducted a study in archived specimens of patients sent for screening for enterovirus. A total of 203 clinical specimens from 184 individuals with painful blister

2015 Southeast Asian Journal of Tropical Medicine and Public Health

11. An Outbreak of Kingella kingae Infections Associated with Hand, Foot and Mouth Disease/Herpangina Virus Outbreak in Marseille, France, 2013. (PubMed)

An Outbreak of Kingella kingae Infections Associated with Hand, Foot and Mouth Disease/Herpangina Virus Outbreak in Marseille, France, 2013. Outbreaks of invasive Kingella kingae infections recently emerged as a new public health concern in daycare centers in Europe, USA and Israel. Despite this, no trigger factor has been yet identified, preventing the setting up of rational measures of control and prevention. We report an outbreak of K. kingae infections associated with hand, foot and mouth (...) disease/herpangina outbreak, and we define the research and policy priorities.From April 22 to May 07, 2013, 5 toddlers presented successive osteo-articular infections in a daycare center in Marseille, France. Real-time polymerase chain reaction targeting the cpn60 gene of K. kingae was used to investigate suspected cases and the prevalence of oropharyngeal K. kingae carriage of their close contacts.The attack rate of the K. kingae infections outbreak was 23.7% (5/21) with no fatality. Positive real

2015 Pediatric Infectious Dsease Journal

12. Herpangina (Diagnosis)

Herpangina (Diagnosis) Herpangina: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjE4NTAyLW92ZXJ2aWV3 processing > Herpangina Updated: Aug 24, 2018 Author: Sandra G Gompf (...) , MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Herpangina Overview Background Herpangina is an acute febrile illness associated with small vesicular or ulcerative lesions on the posterior oropharyngeal structures (enanthem). Herpangina typically occurs during the summer and usually develops in children, occasionally occurring in newborns, adolescents, and young adults. Herpangina is one of many manifestations of and can occur

2014 eMedicine.com

13. Herpangina (Treatment)

Herpangina (Treatment) Herpangina Treatment & Management: Medical Care, Diet, Activity Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjE4NTAyLXRyZWF0bWVudA== processing > Herpangina Treatment & Management Updated (...) : Aug 24, 2018 Author: Sandra G Gompf, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Herpangina Treatment Medical Care Herpangina is a self-limited illness. As such, no specific therapy is indicated. Currently, no antiviral therapy is effective against herpangina. Antibacterial therapy is of no benefit. Recently, considerable efforts have been made in the development of antiviral compounds targeting the capsid protein of enterovirus

2014 eMedicine.com

14. Herpangina (Overview)

Herpangina (Overview) Herpangina: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjE4NTAyLW92ZXJ2aWV3 processing > Herpangina Updated: Aug 24, 2018 Author: Sandra G Gompf (...) , MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Herpangina Overview Background Herpangina is an acute febrile illness associated with small vesicular or ulcerative lesions on the posterior oropharyngeal structures (enanthem). Herpangina typically occurs during the summer and usually develops in children, occasionally occurring in newborns, adolescents, and young adults. Herpangina is one of many manifestations of and can occur

2014 eMedicine.com

15. Herpangina (Follow-up)

Herpangina (Follow-up) Herpangina Follow-up: Further Outpatient Care, Deterrence/Prevention, Complications Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjE4NTAyLWZvbGxvd3Vw processing > Herpangina Follow-up (...) Updated: Aug 24, 2018 Author: Sandra G Gompf, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Herpangina Follow-up Further Outpatient Care Because symptoms associated with herpangina are usually short-lived and resolve within one week, patients generally do not need outpatient follow-up care. Next: Deterrence/Prevention Enteroviruses are spread through the fecal-oral route; therefore, emphasis is placed on measures that may help reduce

2014 eMedicine.com

16. Herpangina

Herpangina Herpangina Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Herpangina Herpangina Aka: Herpangina From Related Chapters II (...) . Epidemiology Occurs in summer months (may be epidemic) III. Etiology Coxsackie Echovirus IV. Symptoms V. Signs Non-toxic appearance Multiple small 1-2 mm or ulcers , posterior pharynx and s Spares the anterior pharynx Contrast which spares the posterior pharynx No skin lesions Unlike VI. Differential Diagnosis s in anterior pharynx, sparing posterior pharynx External s are only seen with HSV (not with Herpangina or ) Images: Related links to external sites (from Bing) These images are a random sampling

2015 FP Notebook

17. Outbreak of hand, foot and mouth disease/herpangina associated with coxsackievirus A6 and A10 infections in 2010, France: a large citywide, prospective observational study. (PubMed)

Outbreak of hand, foot and mouth disease/herpangina associated with coxsackievirus A6 and A10 infections in 2010, France: a large citywide, prospective observational study. Hand, foot and mouth disease (HFMD) and herpangina (HA) are frequently caused by several distinct serotypes belonging to the human enterovirus A species (HEVA). Enterovirus 71 is considered as a significant public health threat because of rare but fatal neurological complications. A sentinel surveillance system involving

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2012 Clinical Microbiology and Infection

18. Risk Factors for Hand, Foot, and Mouth Disease and Herpangina and the Preventive Effect of Hand-washing. (PubMed)

Risk Factors for Hand, Foot, and Mouth Disease and Herpangina and the Preventive Effect of Hand-washing. Hygiene and social distancing are recommended control measures for hand, foot, and mouth disease (HFMD) and herpangina. However, empirical data to support this recommendation are limited.During an outbreak of HFMD and herpangina due to infection by the human enterovirus 71, we defined a case as a vesicular papular rash on the hands, feet, buttocks, or oral mucosa and onset from April 30 (...) to June 26, 2008. We selected 176 HFMD and herpangina case-children and a stratified random sample of 201 asymptomatic control-children; frequency matched according to residency status. We administered a questionnaire to the parents about their children's exposures and hygienic behaviors.Risk factors for HFMD and herpangina included playing with neighborhood children (odds ratio [OR]: 11 [95% confidence interval (CI): 6.2-17]), visiting an outpatient clinic for another reason ≤ 1 week before onset

2011 Pediatrics

19. PHYSICAL PROPERTIES OF TWO GROUP A COXSACKIE (HERPANGINA) VIRUSES WHEN PROPAGATED IN EGGS AND MICE AS DETERMINED BY ULTRACENTRIFUGATION AND ELECTRON MICROSCOPY (PubMed)

PHYSICAL PROPERTIES OF TWO GROUP A COXSACKIE (HERPANGINA) VIRUSES WHEN PROPAGATED IN EGGS AND MICE AS DETERMINED BY ULTRACENTRIFUGATION AND ELECTRON MICROSCOPY 14955517 2004 02 15 2018 12 01 0021-9193 64 2 1952 Aug Journal of bacteriology J. Bacteriol. Physical properties of two group of coxsackie (herpangina) viruses when propagated in eggs and mice as determined by ultracentrifugation and electron microscopy. 237-46 BRIEFS A A BREESE S S SS Jr WARREN J J HUEBNER R J RJ eng Journal Article (...) United States J Bacteriol 2985120R 0021-9193 OM Animals Eggs Enterovirus Herpangina Mice Microscopy, Electron Ultracentrifugation Viruses 5222:41975:122 COXSACKIE VIRUSES 1952 8 1 1952 8 1 0 1 1952 8 1 0 0 ppublish 14955517 PMC169344 J Immunol. 1950 Sep;65(3):337-46 14774516 J Am Med Assoc. 1951 Mar 3;145(9):628-33 14794498 Br J Exp Pathol. 1950 Dec;31(6):809-12 14801366 J Immunol. 1951 Aug;67(2):151-62 14861426 Am J Hyg. 1952 Jan;55(1):83-107 14885169 J Bacteriol. 1952 Jan;63(1):99-105 14927552 Proc

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1952 Journal of bacteriology

20. A New Syndrome of Parotitis with Herpangina Caused by the Coxsackie Virus (PubMed)

A New Syndrome of Parotitis with Herpangina Caused by the Coxsackie Virus 13437259 2002 05 01 2018 12 01 0008-4409 77 1 1957 Jul 01 Canadian Medical Association journal Can Med Assoc J A new syndrome of parotitis with herpangina caused by the Coxsackie virus. 5-7 HOWLETT J G JG SOMLO F F KALZ F F eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 OM Coxsackievirus Infections Enterovirus Herpangina etiology Humans Parotitis etiology Syndrome 5732:35520 HERPANGINA/etiology

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1957 Canadian Medical Association Journal

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