How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

2,191 results for

Hepatotoxic Medication

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

81. Halothane Hepatotoxicity (PubMed)

Halothane Hepatotoxicity 14052979 1996 12 01 2018 12 01 0008-4409 89 1963 Nov 02 Canadian Medical Association journal Can Med Assoc J HALOTHANE HEPATOTOXICITY. 944-6 KERBEL N C NC HILLIARD I M IM eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 EC 2.6.1.1 Aspartate Aminotransferases UQT9G45D1P Halothane OM Anesthesia Anesthesia, Inhalation Anesthesia, Obstetrical Aspartate Aminotransferases Blood Chemical Analysis Chemical and Drug Induced Liver Injury Halothane Hepatitis Kidney

Full Text available with Trip Pro

1963 Canadian Medical Association Journal

82. Allergy to iprindole (Prondol) with hepatotoxicity. (PubMed)

Allergy to iprindole (Prondol) with hepatotoxicity. 5416820 1970 04 16 2016 11 22 0007-1447 1 5692 1970 Feb 07 British medical journal Br Med J Allergy to iprindole (Prondol) with hepatotoxicity. 367 Young P J PJ eng Journal Article England Br Med J 0372673 0007-1447 0 Antidepressive Agents 0 Indoles AIM IM Adult Antidepressive Agents adverse effects Chemical and Drug Induced Liver Injury etiology Depression drug therapy Drug Hypersensitivity etiology Female Humans Indoles adverse effects Liver

Full Text available with Trip Pro

1970 British medical journal

83. Allergy to iprindole (Prondol) with hepatotoxicity. (PubMed)

Allergy to iprindole (Prondol) with hepatotoxicity. 5443418 1970 06 24 2016 11 22 0007-1447 2 5703 1970 Apr 25 British medical journal Br Med J Allergy to iprindole (Prondol) with hepatotoxicity. 238-9 Price J C JC Collings-Wells J A JA eng Journal Article England Br Med J 0372673 0007-1447 0 Antidepressive Agents 0 Indoles AIM IM Adult Antidepressive Agents adverse effects Chemical and Drug Induced Liver Injury etiology Drug Hypersensitivity Female Humans Indoles adverse effects Male Middle

Full Text available with Trip Pro

1970 British medical journal

84. Possible hepatotoxic effect of methadone. (PubMed)

Possible hepatotoxic effect of methadone. 5794138 1969 08 30 2016 11 22 0008-4409 101 2 1969 Jul 26 Canadian Medical Association journal Can Med Assoc J Possible hepatotoxic effect of methadone. 113 Lapierre J J eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 UC6VBE7V1Z Methadone AIM IM Chemical and Drug Induced Liver Injury etiology Hematopoiesis drug effects Humans Infectious Mononucleosis chemically induced Male Methadone adverse effects 1969 7 26 1969 7 26 0 1 1969 7 26 0 0

Full Text available with Trip Pro

1969 Canadian Medical Association Journal

85. Possible hepatotoxic effect of methadone. (PubMed)

Possible hepatotoxic effect of methadone. 5763242 1969 03 06 2013 11 21 0008-4409 100 5 1969 Feb 01 Canadian Medical Association journal Can Med Assoc J Possible hepatotoxic effect of methadone. 265-6 Walter A J AJ eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 UC6VBE7V1Z Methadone AIM IM Humans Liver drug effects Liver Function Tests Methadone adverse effects Substance-Related Disorders 1969 2 1 1969 2 1 0 1 1969 2 1 0 0 ppublish 5763242 PMC1945565

Full Text available with Trip Pro

1969 Canadian Medical Association Journal

86. Allergy to iprindol (Prondol) with hepatotoxicity. (PubMed)

Allergy to iprindol (Prondol) with hepatotoxicity. 5539168 1971 02 24 2016 11 22 0007-1447 1 5740 1971 Jan 09 British medical journal Br Med J Allergy to iprindol (Prondol) with hepatotoxicity. 112 Aylett M J MJ eng Journal Article England Br Med J 0372673 0007-1447 0 Antidepressive Agents 0 Indoles AIM IM Adult Antidepressive Agents adverse effects Chemical and Drug Induced Liver Injury etiology Drug Hypersensitivity Eosinophilia chemically induced Female Humans Indoles adverse effects Liver

Full Text available with Trip Pro

1971 British medical journal

87. Allergy to iprindole (prondol) with hepatotoxicity. (PubMed)

Allergy to iprindole (prondol) with hepatotoxicity. 4922757 1971 02 06 2016 11 22 0007-1447 4 5736 1970 Dec 12 British medical journal Br Med J Allergy to iprindole (prondol) with hepatotoxicity. 682 Waxman D D eng Clinical Trial Journal Article England Br Med J 0372673 0007-1447 0 Antidepressive Agents 0 Indoles AIM IM Antidepressive Agents adverse effects Chemical and Drug Induced Liver Injury etiology Clinical Trials as Topic Humans Indoles adverse effects 1970 12 12 1970 12 12 0 1 1970 12

Full Text available with Trip Pro

1970 British medical journal

88. Allergy to iprindole (Prondole) with hepatotoxicity. (PubMed)

Allergy to iprindole (Prondole) with hepatotoxicity. 5556082 1971 08 27 2016 11 22 0007-1447 2 5763 1971 Jun 19 British medical journal Br Med J Allergy to iprindole (Prondole) with hepatotoxicity. 712 Clift A D AD eng Journal Article England Br Med J 0372673 0007-1447 0 Antidepressive Agents 0 Indoles EC 2.6.1.- Transaminases EC 2.6.1.1 Aspartate Aminotransferases AIM IM Antidepressive Agents adverse effects Aspartate Aminotransferases blood Chemical and Drug Induced Liver Injury enzymology

Full Text available with Trip Pro

1971 British medical journal

89. Allergy to iprindole (prondol) with hepatotoxicity. (PubMed)

Allergy to iprindole (prondol) with hepatotoxicity. 5472818 1970 12 09 2016 11 22 0007-1447 4 5731 1970 Nov 07 British medical journal Br Med J Allergy to iprindole (prondol) with hepatotoxicity. 368-9 Harrison D F DF Stanley I M IM eng Journal Article England Br Med J 0372673 0007-1447 0 Antidepressive Agents 0 Indoles AIM IM Adult Antidepressive Agents adverse effects Chemical and Drug Induced Liver Injury diagnosis Depression drug therapy Female Humans Indoles adverse effects Middle Aged

Full Text available with Trip Pro

1970 British medical journal

90. Allergy to iprindole (Prondole) with hepatotoxicity. (PubMed)

Allergy to iprindole (Prondole) with hepatotoxicity. 5481235 1971 01 12 2016 11 22 0007-1447 4 5733 1970 Nov 21 British medical journal Br Med J Allergy to iprindole (Prondole) with hepatotoxicity. 495 Richards D J DJ eng Journal Article England Br Med J 0372673 0007-1447 0 Antidepressive Agents 0 Indoles AIM IM Antidepressive Agents adverse effects Chemical and Drug Induced Liver Injury epidemiology Humans Indoles adverse effects 1970 11 21 1970 11 21 0 1 1970 11 21 0 0 ppublish 5481235

Full Text available with Trip Pro

1970 British medical journal

91. Allergy to iprindole (Prondole) with hepatotoxicity. (PubMed)

Allergy to iprindole (Prondole) with hepatotoxicity. 5481233 1971 01 12 2016 11 22 0007-1447 4 5733 1970 Nov 21 British medical journal Br Med J Allergy to iprindole (Prondole) with hepatotoxicity. 494 Clein L J LJ eng Journal Article England Br Med J 0372673 0007-1447 0 Antidepressive Agents 0 Indoles AIM IM Antidepressive Agents adverse effects Chemical and Drug Induced Liver Injury etiology Depression drug therapy Humans Indoles adverse effects Male 1970 11 21 1970 11 21 0 1 1970 11 21 0 0

Full Text available with Trip Pro

1970 British medical journal

92. Allergy to iprindole (Prondole) with hepatotoxicity. (PubMed)

Allergy to iprindole (Prondole) with hepatotoxicity. 5481234 1971 01 12 2016 11 22 0007-1447 4 5733 1970 Nov 21 British medical journal Br Med J Allergy to iprindole (Prondole) with hepatotoxicity. 494-5 Cashman M D MD eng Journal Article England Br Med J 0372673 0007-1447 0 Antidepressive Agents 0 Indoles AIM IM Antidepressive Agents adverse effects Chemical and Drug Induced Liver Injury etiology Humans Indoles adverse effects 1970 11 21 1970 11 21 0 1 1970 11 21 0 0 ppublish 5481234

Full Text available with Trip Pro

1970 British medical journal

93. Hepatotoxicity after treatment of schistosomiasis with hycanthone. (PubMed)

Hepatotoxicity after treatment of schistosomiasis with hycanthone. 5018315 1972 06 21 2018 11 13 0007-1447 2 5805 1972 Apr 08 British medical journal Br Med J Hepatotoxicity after treatment of schistosomiasis with hycanthone. 88-9 Farid Z Z Smith J H JH Bassily S S Sparks H A HA eng Journal Article England Br Med J 0372673 0007-1447 0 Xanthenes 3J50XA376E Thymol EC 2.6.1.1 Aspartate Aminotransferases EC 2.6.1.2 Alanine Transaminase EC 3.1.3.1 Alkaline Phosphatase RFM9X3LJ49 Bilirubin AIM IM

Full Text available with Trip Pro

1972 British medical journal

94. Methotrexate hepatotoxicity in psoriasis. (PubMed)

Methotrexate hepatotoxicity in psoriasis. 5022031 1972 07 03 2013 11 21 0007-1447 2 5808 1972 Apr 29 British medical journal Br Med J Methotrexate hepatotoxicity in psoriasis. 296 Ryan T J TJ Sadler G H GH Guerrier C C Vickers H R HR eng Journal Article England Br Med J 0372673 0007-1447 YL5FZ2Y5U1 Methotrexate AIM IM Alcohol Drinking Humans Liver Cirrhosis chemically induced Methotrexate administration & dosage adverse effects Psoriasis drug therapy 1972 4 29 1972 4 29 0 1 1972 4 29 0 0

Full Text available with Trip Pro

1972 British medical journal

95. Hepatotoxicity of sulphamethoxyridazine. (PubMed)

Hepatotoxicity of sulphamethoxyridazine. 5017317 1972 06 17 2018 11 13 0007-1447 2 5806 1972 Apr 15 British medical journal Br Med J Hepatotoxicity of sulphamethoxyridazine. 168 Konttinen A A eng Journal Article England Br Med J 0372673 0007-1447 0 Contraceptives, Oral 25W8454H16 Sulfamethizole EC 2.6.1.1 Aspartate Aminotransferases EC 2.6.1.2 Alanine Transaminase T034E4NS2Z Sulfamethoxypyridazine AIM IM Adult Alanine Transaminase blood Aspartate Aminotransferases blood Chemical and Drug

Full Text available with Trip Pro

1972 British medical journal

96. Tetracycline Hepatotoxicity (PubMed)

Tetracycline Hepatotoxicity 14260641 1996 12 01 2018 12 01 0007-1447 1 5440 1965 Apr 10 British medical journal Br Med J TETRACYCLINE HEPATOTOXICITY. 995 BREWER T T eng Journal Article England Br Med J 0372673 0007-1447 F8VB5M810T Tetracycline OM Chemical and Drug Induced Liver Injury Drug Therapy Fatty Liver Female Hepatitis Hepatitis A Pregnancy Pregnancy Complications Pregnancy Complications, Infectious Tetracycline Toxicology DRUG THERAPY FATTY LIVER HEPATITIS, TOXIC PREGNANCY PREGNANCY

Full Text available with Trip Pro

1965 British medical journal

97. Tetracycline Hepatotoxicity (PubMed)

Tetracycline Hepatotoxicity 14211749 1996 12 01 2018 12 01 0007-1447 2 5424 1964 Dec 19 British medical journal Br Med J TETRACYCLINE HEPATOTOXICITY. 1545-6 eng Journal Article England Br Med J 0372673 0007-1447 0 Anti-Bacterial Agents 0 Protein Synthesis Inhibitors F8VB5M810T Tetracycline OM Anti-Bacterial Agents Gastrointestinal Diseases Protein Synthesis Inhibitors Tetracycline Toxicology TOXICOLOGIC REPORT 1964 12 19 1964 12 19 0 1 1964 12 19 0 0 ppublish 14211749 PMC1817573 AMA Arch Intern

Full Text available with Trip Pro

1964 British medical journal

98. High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury. (PubMed)

High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury. Drug-induced liver injury (DILI) is a leading cause of drug failure in clinical trials and a major reason for drug withdrawals from the market. Although there is evidence that dosages of ≥100 mg/day are associated with increased risk for hepatotoxicity, many drugs are safe at such dosages. There is an unmet need to predict risk for DILI more reliably, and lipophilicity (...) might be a contributing factor. We analyzed the combined factors of daily dose and lipophilicity for 164 US Food and Drug Administration-approved oral medications and observed high risk for hepatotoxicity (odds ratio [OR], 14.05; P < 0.001) for drugs given at dosages ≥100 mg/day and octanol-water partition coefficient (logP) ≥3. This defined the "rule-of-two." Similar results were obtained for an independent set of 179 oral medications with 85% of the rule-of-two positives being associated

Full Text available with Trip Pro

2012 Hepatology

99. NAT2 Genotyping in Re-challenge Protocol of INH Titration in Patients With Anti-TB Medications-induced Hepatitis

for isoniazid (INH) titration in patients with anti-tuberculosis medication-induced hepatitis. Condition or disease Intervention/treatment Phase Hepatotoxicity Drug: isoniazid Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 60 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Supportive Care Official Title: The Application of the N-acetyltransferase 2 (NAT2) Genotyping (...) in Re-challenge Protocol of Isoniazid (INH) Titration in Patients With Anti-TB Medications-induced Hepatitis Study Start Date : November 2007 Estimated Primary Completion Date : November 2015 Estimated Study Completion Date : November 2015 Resource links provided by the National Library of Medicine related topics: available for: resources: Arms and Interventions Go to Arm Intervention/treatment Experimental: isoniazid rechalleng When patients encountered hepatotoxicity during the anti-TB treatment

2012 Clinical Trials

100. Hepatotoxicity

[ ] Neoplasms have been described with prolonged exposure to some medications or toxins. Hepatocellular carcinoma, angiosarcoma, and liver adenomas are the ones usually reported. Causes: , , , , Diagnosis [ ] Algorithm for suspected drug-induced hepatic toxicity This remains a challenge in clinical practice due to a lack of reliable markers. Many other conditions lead to similar clinical as well as pathological pictures. To diagnose hepatotoxicity, a causal relationship between the use of the toxin or drug (...) of hepatotoxicity: , , , , , , and . See also [ ] References [ ] Friedman, Scott E.; Grendell, James H.; McQuaid, Kenneth R. (2003). Current diagnosis & treatment in gastroenterology . New York: Lang Medical Books/McGraw-Hill. pp. 664–679. . Dixit, Vaibhav A. (2019). "A simple model to solve a complex drug toxicity problem". Toxicology Research . : . Greenhough S, Hay DC (2012). "Stem Cell-Based Toxicity Screening: Recent Advances in Hepatocyte Generation". Pharm Med . 26 (2): 85–89. : . McNally, Peter F. (2006

2012 Wikipedia

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>