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Hepatitis C Serology

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1. Evaluation of hepatitis C, hepatitis B, and HIV virus Serology pandemic in thalassemia patients of Shahid Mohammadi Hospital of Bandar Abbas, Iran (PubMed)

Evaluation of hepatitis C, hepatitis B, and HIV virus Serology pandemic in thalassemia patients of Shahid Mohammadi Hospital of Bandar Abbas, Iran Thalassemia patients are prone to the hepatitis C, B, and HIV virus, due to their constant need to receive blood transfusions. Therefore, this research was aimed to determine the epidemic of the aforementioned diseases in thalassemia patients of Shahid Mohammadi Hospital of Bandar Abbas, Iran.This cross-sectional study was carried out on thalassemia (...) patients visiting the Thalassemia Hospital of Bandar Abbas from March 21, 2014, to March 22, 2015. Checklists were used to collect the data. HBS-Ag, HCV-Ab, and HIV-Ab tests have been registered for hepatitis B, hepatitis C, and HIV virus, respectively. The data were analyzed using SPSS 19 by Mann-Whitney U test, chi-square test, and independent samples t-test.Among 587 records administered into the research, 280 individuals (47.7 %) were men and (52.3 %) were female. The average age of participants

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2017 Electronic physician

2. Validation of Multiplex Serology for human hepatitis viruses B and C, human T-lymphotropic virus 1 and Toxoplasma gondii. (PubMed)

Validation of Multiplex Serology for human hepatitis viruses B and C, human T-lymphotropic virus 1 and Toxoplasma gondii. Multiplex Serology is a high-throughput technology developed to simultaneously measure specific serum antibodies against multiple pathogens in one reaction vessel. Serological assays for hepatitis B (HBV) and C (HCV) viruses, human T-lymphotropic virus 1 (HTLV-1) and the protozoan parasite Toxoplasma gondii (T. gondii) were developed and validated against established (...) reference assays. For each pathogen, between 3 and 5 specific antigens were recombinantly expressed as GST-tag fusion proteins in Escherichia coli and tested in Monoplex Serology, i.e. assays restricted to the antigens from one particular pathogen. For each of the four pathogen-specific Monoplex assays, overall seropositivity was defined using two pathogen-specific antigens. In the case of HBV Monoplex Serology, the detection of past natural HBV infection was validated based on two independent reference

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2019 PLoS ONE

3. Screening hemodialysis patients for hepatitis C in Vietnam: the inconsistency between common hepatitis C virus serological and virological tests. (PubMed)

Screening hemodialysis patients for hepatitis C in Vietnam: the inconsistency between common hepatitis C virus serological and virological tests. Selecting the appropriate screening method and interval for the early detection of hepatitis C virus (HCV) infection in low-resourced haemodialysis settings is a challenge. The challenge occurs when patients are classified as HCV-RNA positive but negative to HCV-core antigen (HCV-coreAg), anti-HCV and genotyping tests. We aim to clarify

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2018 Journal of viral hepatitis

4. Autoimmune liver serology before and after successful treatment of chronic hepatitis C by direct acting antiviral agents. (PubMed)

Autoimmune liver serology before and after successful treatment of chronic hepatitis C by direct acting antiviral agents. Chronic hepatitis C virus (HCV) infection is associated with a wide range of immunopathological manifestations, which are significantly improved by successful interferon-based treatment. There is paucity of data on the impact of interferon-free HCV clearance on immunopathological manifestations, which might be expected to disappear more frequently as compared to what (...) reported in interferon-induced HCV-clearance. We have investigated liver autoimmune serology before and after interferon-free clearance of HCV by treatment with direct acting antiviral agents (DAA).Patients within the Swiss Hepatitis C Cohort Study who underwent successful (SVR 12) HCV treatment with DAA were tested for autoimmune liver serology according to dedicated guidelines before and at least 6 months after end of treatment.A total of 235 patients were included; 62% males; median age 56 years; 27

2019 Journal of Autoimmunity

5. Economic Comparison of Serologic and Molecular Screening Strategies for Hepatitis C Virus (PubMed)

Economic Comparison of Serologic and Molecular Screening Strategies for Hepatitis C Virus Background: Hepatitis C virus (HCV) screening is traditionally performed using an enzyme-linked immunosorbent assay (ELISA), and HCV infection is confirmed by measuring the viral load using polymerase chain reaction (PCR). An alternative screening approach is to use only PCR, without the ELISA pretest. Methods: We compared the cost ratio of screening for HCV using 2 approaches: (1) ELISA followed by PCR

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2018 Gastroenterology & hepatology

6. Helicobacter Pylori Serology in Relation to Hepatitis C Virus Infection and IL28B Single Nucleotide Polymorphism (PubMed)

Helicobacter Pylori Serology in Relation to Hepatitis C Virus Infection and IL28B Single Nucleotide Polymorphism The aim of the study was to evaluate the serological rate of Helicobacter pylori (H. pylori) infection in patients with chronic hepatitis C virus (HCV) infection and determine any correlations with liver damage and IL28B single-nucleotide polymorphism (SNP). One hundred eighty-nine patients with chronic HCV infection were included in the study, and H. pylori status was defined based (...) on anti-H. pylori-IgG or anti-CagA-IgG antibodies using enzyme-linked immunosorbent assay (ELISA). Liver damage was assessed using histology or transient elastography. IL28B C/T polymorphism (rs12979860) was evaluated in circulating blood cells using a PCR-based restriction fragment length polymorphism assay. Overall H. pylori serology was positive in 38.1% of our HCV-infected subjects. Among those, the anti-CagA-IgG positivity rate was 43.1% and was within the range of previously described

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2018 Journal of clinical medicine

7. Public health guidance on HIV, hepatitis B and C testing in the EU/EEA

Public health guidance on HIV, hepatitis B and C testing in the EU/EEA SCIENTIFIC AD VICE www.ecdc.europa.eu Public health guidance on HIV, hepatitis B and C testing in the EU/EEA An integrated approachECDC SCIENTIFIC ADVICE Public health guidance on HIV, hepatitis B and C testing in the EU/EEA An integrated approach ii This guidance was commissioned by the European Centre for Disease Prevention and Control (ECDC), coordinated by Andrew J Amato-Gauci and Lara Tavoschi with the support of Helena (...) guidance on HIV, hepatitis B and C testing in the EU/EEA – An integrated approach. Stockholm: ECDC; 2018. Stockholm, November 2018 PDF Print ISBN 978-92-9498-286-5 ISBN 978-92-9498-294-0 DOI 10.2900/79127 DOI 10.2900/489464 Catalogue number TQ-06-18-328-EN-N Catalogue number TQ-06-18-328-EN-C © European Centre for Disease Prevention and Control, 2018 Cover picture: © iStock Reproduction is authorised, provided the source is acknowledged. For any use or reproduction of photos or other material

2019 European Centre for Disease Prevention and Control - Public Health Guidance

8. Diagnostic accuracy of serological diagnosis of hepatitis C and B using dried blood spot samples (DBS): two systematic reviews and meta-analyses. (PubMed)

Diagnostic accuracy of serological diagnosis of hepatitis C and B using dried blood spot samples (DBS): two systematic reviews and meta-analyses. Dried blood spots (DBS) are a convenient tool to enable diagnostic testing for viral diseases due to transport, handling and logistical advantages over conventional venous blood sampling. A better understanding of the performance of serological testing for hepatitis C (HCV) and hepatitis B virus (HBV) from DBS is important to enable more widespread

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2017 BMC Infectious Diseases

10. Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Infections in Obstetrician?Gynecologists

Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Infections in Obstetrician?Gynecologists Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Infections in Obstetrician–Gynecologists - ACOG Menu ▼ Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Infections in Obstetrician–Gynecologists Page Navigation ▼ Number 655, February 2016 (Reaffirmed 2018) Committee on Gynecologic Practice This Committee Opinion was developed by the American College of Obstetricians (...) and Gynecologists’ Committee on Gynecological Practice. This document reflects emerging clinical and scientific advances as of the date issued and is subject to change. The information should not be construed as dictating an exclusive course of treatment or procedure to be followed. Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Infections in Obstetrician–Gynecologists ABSTRACT: To prevent transmission of bloodborne pathogens, it is important that health care providers adhere to standard precautions

2016 American College of Obstetricians and Gynecologists

11. Prevalence of hepatitis B and hepatitis C among diabetes mellitus type 2 individuals. (PubMed)

Prevalence of hepatitis B and hepatitis C among diabetes mellitus type 2 individuals. Diabetes mellitus type 2 (DM2) patients have higher risk to be infected with parenterally transmitted viruses, like hepatitis B or C virus. This study aims to determine HBV and HCV infection prevalence in DM2 patients from Northeast and Southeast Brazil. A total of 537 DM2 patients were included, 194 (36.12%) males and 343 (63.87%) females, with mean age of 57.13±11.49 years. HBV and HCV markers were (...) determined using serological and molecular analysis, and risk factors were evaluated in a subgroup from Southeast (n = 84). Two HBV acute (HBsAg+/anti-HBc -) and one HBV chronic case (HBsAg+/anti-HBc+) were found. Six individuals (1.1%) were isolated anti-HBc, 37 (6.9%) had HBV infection resolved (anti-HBc+/anti-HBs+), 40 (7.4%) were considered HBV vaccinated (anti-HBc-/anti-HBs+). Thirteen patients (2.42%) had anti-HCV and 7 of them were HCV RNA+. In the subgroup, anti-HBc positivity was associated

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2019 PLoS ONE

12. Serologic Responses and Effectiveness of Hepatitis A Vaccination Among HIV-Positive Individuals During the Outbreak of Acute Hepatitis A. (PubMed)

Serologic Responses and Effectiveness of Hepatitis A Vaccination Among HIV-Positive Individuals During the Outbreak of Acute Hepatitis A. Outbreaks of hepatitis A virus (HAV) infection have been occurring among men who have sex with men in the Asia-Pacific region, the United States, and several European countries since June 2015 and recently among persons who are homeless and use illicit drugs in the United States. We evaluated the serologic responses and effectiveness of HAV vaccination (...) ; our data highlight the importance of HAV serologic screening and vaccination to prevent outbreaks of acute hepatitis A in at-risk populations. (Hepatology 2018;68:22-31).© 2018 by the American Association for the Study of Liver Diseases.

2018 Hepatology

13. Evaluation of elastography combined with serological indexes for hepatic fibrosis in patients with chronic hepatitis B (PubMed)

Evaluation of elastography combined with serological indexes for hepatic fibrosis in patients with chronic hepatitis B To investigate the value of ultrasound elastography combined with serological indexes in diagnosing liver fibrosis and assessing its severity.A total of 338 chronic hepatitis B (CHB) patients were divided into a disease group (patients with hepatic fibrosis) and control group (subjects without hepatic fibrosis). The disease group was further divided into S1-S4 according (...) to the degree of fibrosis. Independent risk factors for hepatic fibrosis were analyzed using multivariate logistic regression. The diagnostic values of hepatic fibrosis from different indicators were compared using receiver operating characteristic (ROC) curves. The combination of elastography and serological indexes was explored to assess the severity of hepatic fibrosis.The multivariate logistic regression analysis results revealed that shear wave velocity (SWV), hyaluronic acid (HA), type IV collagen

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2018 World Journal of Gastroenterology

14. Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection (PubMed)

Role of Serologic and Molecular Diagnostic Assays in Identification and Management of Hepatitis C Virus Infection The drugs available for the treatment of hepatitis C virus (HCV) have evolved to provide shorter treatment duration and higher rates of sustained virologic response (SVR), and the role of HCV infection diagnostic tests has had to evolve in order to meet changing clinical needs. This review gives an overview on the role of HCV infection diagnostic testing (molecular and serological

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2016 Journal of clinical microbiology

15. Hepatitis C Serology

Hepatitis C Serology Hepatitis C Serology Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Hepatitis C Serology Hepatitis C Serology (...) Aka: Hepatitis C Serology , Hepatitis C Antibody , Hepatitis C Virus Antibody , Anti-HCV RNA , xHCV Antibody , xHCV Ab , xHCV IgG , RT-PCR for HCV RNA , EIA for Anti-HCV II. Course of Anti-HCV Antibody Present in up to 70% at onset of symptoms Present in 90% of cases at 3 months Present in most cases by 6 months post-exposure III. Screening Tests ELISA-1 (replaced by ELISA-2) Detects seroconversion 15-20 weeks after exposure Sensitivity: 81-89% : Poor (High rate of false positives) ELISA-2

2018 FP Notebook

16. The Association of Hepatitis C Serological Status with Several Risk Factors in Indonesia (PubMed)

The Association of Hepatitis C Serological Status with Several Risk Factors in Indonesia Hepatitis is an inflammation of the liver commonly caused by viral infection such as hepatitis A, B, C, D, and E but it is also possible by other causes. Infection with hepatitis C virus is also referred to as a disguise because the early infection is often asymptomatic that often goes undetected. This study aims at determining the several associated risk factors with hepatitis C serological status (...) . The study design is cross-sectional. The biomedical data collection was carried out in 33 provinces in Indonesia with a population in urban blocks, census in Indonesia, where the sample is all household members over the age of one year from selected households by signing the informed consent. Total block census in selected urban area is about 971-block census with a total sample of 15.536 households. The results showed that there is a correlation between hepatitis C serological status and demographic

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2016 International scholarly research notices

17. A Study on the Age-Related Changes in Hepatitis B and C Virus Serology (PubMed)

A Study on the Age-Related Changes in Hepatitis B and C Virus Serology There are a limited number of studies on the seroprevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infection in Turkey. This study aimed to compare HBV and HCV seroprevalence rates before and after the implementation of national hepatitis B vaccination program (NHPVP) and to explore age-related changes in the seroprevalences.Results of Hepatitis B surface antigen (HBsAg), Hepatitis B virus surface antibody

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2016 The Eurasian journal of medicine

18. Serological Tests Do Not Predict Residual Fibrosis in Hepatitis C Cirrhotics with a Sustained Virological Response to Interferon (PubMed)

Serological Tests Do Not Predict Residual Fibrosis in Hepatitis C Cirrhotics with a Sustained Virological Response to Interferon Liver biopsy (LB) has lost popularity to stage liver fibrosis in the era of highly effective anti-hepatitis C virus (HCV) therapy, yet diagnosis of persistent cirrhosis may have important implications following HCV eradication. As performance of serological non-invasive tests (NITs) to predict residual fibrosis in non-viremic HCV patients is unknown, we investigated

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2016 PloS one

19. Serological Testing for Suspected Viral Hepatitis

). ? If hepatitis A infection alone is suspected, request IgM antibody to hepatitis A virus (anti-HA V IgM) only. ? If hepatitis B infection alone is suspected, request hepatitis B surface antigen (Hb- sAg) only. ? Refer to Appendix A (Suspected Acute Hepatitis Algorithm) CHRONIC VIRAL HEPATITIS ? If chronic viral hepatitis is suspected, request hepatitis B surface antigen (HbsAg) and antibody to hepatitis C (anti-HCV). Serological Testing for Suspected Viral Hepatitis | January 2006 Clinical Practice Guideline (...) , if a patient is positive for hepatitis A, B, C, or D. REFERENCES 1. Kumar S, Pound DC. Serologic diagnosis of viral hepatitis. Postgrad Med. 1992; 92(4):55-68. 2. Kools AM. Hepatitis A, B, C, D, and E. Postgrad Med. 1992;91 (3):109-14. 3. Main J, Jacyna MR, Thomas HC. The diagnosis and management of viral hepatitis. CDR. 1992:2;2(10): R117-20. 4. CCDR. Notifiable diseases annual summary– 1994,1996; 22S1:42-7, 64-9. 5. Notifiable diseases annual summary Alberta, 1995. 6. Iwarson S, Norkrans G, Wejstal R

2014 Toward Optimized Practice

20. Evaluation of hepatitis A, B, and C serology in patients with cirrhosis and intensive alcohol consumption (PubMed)

Evaluation of hepatitis A, B, and C serology in patients with cirrhosis and intensive alcohol consumption The objective of this study was to evaluate the serology of hepatitis A, B, and C in patients with cirrhosis and intensive alcohol consumption.We retrospectively reviewed the viral serology results of 817 patients with cirrhosis and intensive alcohol consumption who presented to the Gastroenterology Clinic of Atatürk Training and Research Hospital of Izmir Katip Çelebi University between (...) in three patients. Of the patients with HBV, 10.0% had HBeAg and 7.6% had anti-delta. One-hundred and two (12.5%) patients had HCC, and of these, six (5.9%) were HCV-positive and 53 (52.0%) were HBsAg-positive.Patients with cirrhosis and intensive alcohol consumption have an increased hepatitis B and C prevalence. Patients with chronic viral hepatitis with alcohol habit are at a higher risk for HCC. Therefore, patients with cirrhosis and intensive alcohol consumption should be screened for hepatitis B

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2018 Northern clinics of Istanbul

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