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186 results for

Helicobacter pylori Noninvasive Testing

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181. 13C-urea breath test for the diagnosis of Helicobacter pylori infection. A further simplification for clinical practice. (Abstract)

13C-urea breath test for the diagnosis of Helicobacter pylori infection. A further simplification for clinical practice. The 13C-urea breath test is the most accurate noninvasive method for the diagnosis of Helicobacter pylori infection. The oral administration of citric acid solution as test drink 10 min before administration of 13C-urea appears to be the most valuable test procedure hitherto reported. To simplify the test for clinical routine, we evaluated in a prospective, randomized (...) , crossover study the accuracy of a new modification that consists in giving the 13C-urea dissolved in the test drink.Forty dyspeptic patients were studied. H. pylori status was assessed by histology, rapid urease test, and culture. A 13C-urea breath test was performed on 2 consecutive days by giving 200 ml 0.1N citric acid solution either 10 min previous to (protocol 1) or simultaneously with (protocol 2) the administration of 75 mg 13C-urea in randomized order. The 13CO2/12CO2 ratio was measured

1998 Scandinavian journal of gastroenterology Controlled trial quality: uncertain

182. The Helicobacter pylori breath test: a surrogate marker for peptic ulcer disease in dyspeptic patients. Full Text available with Trip Pro

The Helicobacter pylori breath test: a surrogate marker for peptic ulcer disease in dyspeptic patients. There is interest in noninvasive H pylori testing as a means of predicting diagnosis and determining management in dyspeptic patients.To assess the value of the 14C urea breath test as a predictor of peptic ulcer disease in patients presenting with dyspepsia.327 consecutive patients referred for investigation of dyspepsia had a 14C urea breath test performed before endoscopy. Patients were (...) not included if they had previously confirmed ulcer disease, previous gastric surgery, or were taking non-steroidal anti-inflammatory drugs.Of the 182 patients with a positive 14C urea breath test, duodenal and/or gastric ulcers were present in 45% and erosive duodenitis in a further 2%. Oesophagitis was present in 12% of the breath test positive patients with two thirds of the oesophagitis patients having co-existent ulcer disease. The prevalence of ulcer disease in the H pylori positive dyspeptic

1997 Gut

183. Accuracy of the stool antigen test for the diagnosis of childhood Helicobacter pylori infection: a multicenter Japanese study. (Abstract)

Accuracy of the stool antigen test for the diagnosis of childhood Helicobacter pylori infection: a multicenter Japanese study. The (13)C-urea breath test (UBT) has been accepted as a reliable noninvasive test for detecting Helicobacter pylori infection. Recently, another noninvasive test, a new enzyme immunoassay for H. pylori antigens in stool, has been widely investigated for its clinical usefulness. The purpose of this multicenter study was to evaluate the diagnostic accuracy of the stool (...) cutoff value of absorbance at 450/630 nm was 0.110. When a single cutoff value of 0.110 without indeterminate results was used, the sensitivity, specificity, and accuracy were 96.1% (95% CI = 90.8-99.7%), 96.3% (95% CI = 93.6-99.0%), and 96.2% (95% CI = 93.9-98.5%), respectively. In 19 patients in whom H. pylori was successfully eradicated, HpSA results were negative at 1 month of follow-up and remained negative through 6 months.The HpSA is an accurate test for the detection of H. pylori infection

2003 American Journal of Gastroenterology

184. Breath test using a single 50-mg dose of 13C-urea to detect Helicobacter pylori infection in children. (Abstract)

Breath test using a single 50-mg dose of 13C-urea to detect Helicobacter pylori infection in children. The 13C-urea breath test is an accurate, noninvasive method for the diagnosis of in adults. A dose of 75 to 100 mg of urea is generally used, especially in adults, but the optimal dose in children is still unknown. Our aim was to determine whether urea breath test performed with a single 50-mg dose of 13C-urea was sufficient and accurate for diagnosing infection in children.Consecutive (...) children 4 to 14 years of age undergoing upper intestinal endoscopy to evaluate symptoms of recurrent abdominal pain were prospectively included. Exclusion criteria included use of antibiotics or proton pump inhibitors during the last month, gastric surgery, and previous eradication therapy. Reference criteria for diagnosis of infection were based on histology, culture, and serology. Urea breath test (TAU-KIT; Isomed, S.L., Madrid, Spain) was performed as follows: citric acid (Citral pylori) dissolved

2003 Journal of Pediatric Gastroenterology and Nutrition

185. Noninvasive detection of Helicobacter pylori infection in clinical practice: the 13C urea breath test. (Abstract)

Noninvasive detection of Helicobacter pylori infection in clinical practice: the 13C urea breath test. To validate the 13C urea breath test for the detection of Helicobacter pylori infection both before and after treatment.13C urea breath tests with 125-mg and 250-mg doses were carried out on each of 60 infected and 60 noninfected subjects. Results were compared with histological examination of gastric biopsies to establish detection limits. The best cut-off point was used in a clinical trial (...) % at 30 min, the accuracy was 94.8 (95% confidence interval = 92-97%) before antimicrobial therapy and 95.4% (95% confidence interval = 91-98%) after. An increase of 2.4% in the abundance of breath 13CO2 measured 30 min after a 125-mg dose of 13C urea reliably indicated the presence of active H.pylori infection either before or after antimicrobial therapy. The 13C urea breath test provides a simple and reliable and noninvasive method of assessing H.pylori status.

1996 The American journal of gastroenterology Controlled trial quality: uncertain

186. Lack of accuracy of the noninvasive Helicobacter pylori stool antigen test in patients with gastroduodenal ulcer bleeding. (Abstract)

Lack of accuracy of the noninvasive Helicobacter pylori stool antigen test in patients with gastroduodenal ulcer bleeding. Oral presentation at Digestive Diseases Week, San Francisco, California, May 2002. The antigen-based stool assay has proven to be accurate in diagnosing Helicobacter pylori infection in dyspeptic patients. We evaluated the H. pylori antigen-based stool assay (HpSA) in patients with peptic ulcer bleeding (PUB).Thirty-six patients with PUB were endoscoped, and antral (...) and corpus biopsy specimens were taken for rapid urease test (RUT), histology, and culture. The first stool sample after admission was collected for the HpSA test. The gold standard was defined as either positive culture or positive RUT and histology. If only RUT or histology was positive, this was defined as indeterminate. To evaluate cross-reaction with blood constituents, citrated blood samples from 10 healthy volunteers (nine H. pylori serology negative and one H. pylori serology positive) were

2003 American Journal of Gastroenterology

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