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Heat Illness Prevention

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1. General medicine: Heat-related chronic kidney disease mortality in the young and old: differing mechanisms, potentially similar solutions?

healthy young adults at risk of mesoamerican nephropathy . 22. Bhaskaran K , Armstrong B , Hajat S , et al . Heat and risk of myocardial infarction: hourly level case-crossover analysis of MINAP database . 23. Centers for Disease Control and Prevention (CDC) . Heat-related mortality-Chicago, July 1995 . 24. Wegman DH , Apelqvist J , Bottai M , et al . Intervention to diminish dehydration and kidney damage among sugarcane workers . 25. Bodin T , García-Trabanino R , Weiss I , et al . Intervention (...) to reduce heat stress and improve efficiency among sugarcane workers in El Salvador: Phase 1 . 26. U.S. Department of Health and Human Services. Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health . NIOSH criteria for a recommended standard: occupational exposure to heat and hot environments . Cincinnati : NIOSH , 2016 . Footnotes Contributors TÓF: first author, wrote the first, subsequent and final drafts, as well as background reading/review of prior

2019 Evidence-Based Medicine

2. CRACKCast E141 – Heat Illness

are the highest risk athlete group for heat illness Older adults and the poor, who often lack adequate air conditioning and nutrition, and those with preexisting disease are prone to heat illness during environmental extremes. It is estimated that at least 10 times as many heat-aggravated illnesses occur in patients with comorbid conditions, such as coronary artery disease, cerebrovascular disease, and diabetes. During heat waves, many deaths are prevented due to air conditioning units. Let’s talk about HEAT (...) and a decrease in cerebral perfusion leading to a LOC Usually a multifactorial disorder, but elderly people are more fragile and at risk for it Do that full hx, physical and let that guide your workup True heat syncope is self-limited and can be prevented with acclimatization, active muscle movement, compression garments, and a euvolemic state [3] Describe the types of major heat illness Heat exhaustion A clinical syndrome of volume depletion during heat stress Usually individuals working in a hot

2018 CandiEM

3. Heat Sepsis Precedes Heat Toxicity in the Pathophysiology of Heat Stroke—A New Paradigm on an Ancient Disease Full Text available with Trip Pro

Heat Sepsis Precedes Heat Toxicity in the Pathophysiology of Heat Stroke—A New Paradigm on an Ancient Disease Heat stroke (HS) is an ancient illness dating back more than 2000 years and continues to be a health threat and to cause fatality during physical exertion, especially in military personnel, fire-fighters, athletes, and outdoor laborers. The current paradigm in the pathophysiology and prevention of HS focuses predominantly on heat as the primary trigger and driver of HS, which has (...) not changed significantly for centuries. However, pathological and clinical reports from HS victims and research evidence from animal and human studies support the notion that heat alone does not fully explain the pathophysiology of HS and that HS may also be triggered and driven by heat- and exercise-induced endotoxemia. Exposure to heat and exercise stresses independently promote the translocation of lipopolysaccharides (LPS) from gram-negative bacteria in the gut to blood in the circulatory system

2018 Antioxidants

4. Infectious Diseases Society of America Guidelines on Infection Prevention for Health Care Personnel Caring for Patients with Suspected or Known COVID-19

including Google Scholar, World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) websites. Horizon scans were performed daily during the evidence assessment and recommendation process to locate additional grey literature and manuscript pre-prints. Reference lists and literature suggested by panelists were reviewed for inclusion. The reference lists of relevant articles were scanned for additional studies. Indirect evidence related to Severe Acute Respiratory Syndrome (SARS (...) Infectious Diseases Society of America Guidelines on Infection Prevention for Health Care Personnel Caring for Patients with Suspected or Known COVID-19 Last updated April 30, 2020 at 10:00 AM EDT and posted online at www.idsociety.org/COVID19guidelines/ip. Please check website for most updated version of these guidelines. Version 1.0.1 Infectious Diseases Society of America Guidelines on Infection Prevention for Health Care Personnel Caring for Patients with Suspected or Known COVID-19 Authors

2020 Infectious Diseases Society of America

5. α-Lipoic acid prevents the intestinal epithelial monolayer damage under heat stress conditions: model experiments in Caco-2 cells Full Text available with Trip Pro

α-Lipoic acid prevents the intestinal epithelial monolayer damage under heat stress conditions: model experiments in Caco-2 cells Under conditions of high ambient temperatures and/or strenuous exercise, humans and animals experience considerable heat stress (HS) leading among others to intestinal epithelial damage through induction of cellular oxidative stress. The aim of this study was to characterize the effects of α-Lipoic Acid (ALA) on HS-induced intestinal epithelial injury using (...) an in vitro Caco-2 cell model.A confluent monolayer of Caco-2 cells was pre-incubated with ALA (24 h) prior to control (37 °C) or HS conditions (42 °C) for 6 or 24 h and the expression of heat shock protein 70 (HSP70), heat shock factor-1 (HSF1), and the antioxidant Nrf2 were investigated. Intestinal integrity was determined by measuring transepithelial resistance, paracellular permeability, junctional complex reassembly, and E-cadherin expression and localization. Furthermore, cell proliferation

2017 European journal of nutrition

6. Preventive measures and lifestyle habits against exertional heat illness in radiation decontamination workers Full Text available with Trip Pro

Preventive measures and lifestyle habits against exertional heat illness in radiation decontamination workers The aim of this study was to reveal the current state of preventive measures and lifestyle habits against heat illness in radiation decontamination workers and to examine whether young radiation decontamination workers take less preventive measures and have worse lifestyle habits than the elder workers.This was a cross-sectional study. Self-administered questionnaires were sent to 1,505 (...) radiation decontamination workers in Fukushima, Japan. Five hundred fifty-eight men who replied and answered all questions were included in the statistical analysis. The questionnaire included age, duration of decontamination work, previous occupation, lifestyle habit, and preventive measures for heat illness. We classified age of the respondents into five groups: <30, 30-39, 40-49, 50-59, and ≥60 years and defined the workers under 30 years of age as young workers. Logistic regression analysis was used

2017 Journal of occupational health

7. Preventing heat illness in the anticipated hot climate of the Tokyo 2020 Summer Olympic Games Full Text available with Trip Pro

Preventing heat illness in the anticipated hot climate of the Tokyo 2020 Summer Olympic Games Amid the effects of global warming, Tokyo has become an increasingly hot city, especially during the summertime. To prepare for the upcoming 2020 Summer Olympics and Paralympics in Tokyo, all participants, including the athletes, staff, and spectators, will need to familiarize themselves with Tokyo's hot and humid summer conditions. This paper uses the wet-bulb globe temperature (WBGT) index, which (...) Tokyo Olympics. We also found that Tokyo had a higher WBGT than any of those previous host cities and is poorly suited for outdoor sporting events. Combined efforts by the official organizers, government, various related organizations, and the participants will be necessary to deal with these challenging conditions and to allow athletes to perform their best, as well as to prevent heat illnesses among staff and spectators. The sporting committees, as well as the Olympic organizing committee, should

2017 Environmental health and preventive medicine

8. Recruitment, Methods and Descriptive Results of a Physiologic Assessment of Latino Farmworkers: the California Heat Illness Prevention Study (CHIPS) Full Text available with Trip Pro

Recruitment, Methods and Descriptive Results of a Physiologic Assessment of Latino Farmworkers: the California Heat Illness Prevention Study (CHIPS) The California heat illness prevention study (CHIPS) devised methodology and collected physiological data to assess heat related illness (HRI) risk in Latino farmworkers.Bilingual researchers monitored HRI across a workshift, recording core temperature, work rate (metabolic equivalents [METs]), and heart rate at minute intervals. Hydration status (...) was assessed by changes in weight and blood osmolality. Personal data loggers and a weather station measured exposure to heat. Interviewer administered questionnaires were used to collect demographic and occupational information.California farmworkers (n = 588) were assessed. Acceptable quality data was obtained from 80% of participants (core temperature) to 100% of participants (weight change). Workers (8.3%) experienced a core body temperature more than or equal to 38.5 °C and 11.8% experienced

2017 Journal of Occupational and Environmental Medicine

9. Heat Induced Illness (Hyperthermia): First Aid Management

• excessive heat production from metabolic activity • failure of the cooling mechanisms • an alteration in the body’s set temperature. Factors which may contribute to heat induced illness include: • excessive physical exertion • hot climatic conditions with high humidity • inadequate fluid intake • infection (particularly a viral illness) • inappropriate environments (e.g. unventilated hot buildings) • wearing unsuitably heavy, dark clothing on hot days • drugs which affect heat regulation. The very young (...) 1, 2, 3 and very old 4 are more prone to heat induced illness. 2 Prevention On warm, humid or hot days: • keep infants and the elderly in cool, ventilated areas and provide ample oral fluids • wear light coloured, loose-fitting clothing during physical exertion and hats during outside activities • take adequate fluids during exertion on hot days – thirst is a useful guide to required fluid intake. ANZCOR Guideline 9.3.4 January 2016 Page 2 of 3 For participants in, and organisers of sporting

2016 Australian Resuscitation Council

10. Heat Illness Prevention

Heat Illness Prevention Heat Illness Prevention Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Heat Illness Prevention Heat Illness (...) Prevention Aka: Heat Illness Prevention II. Prevention Measures Identify high risk patients See See Limit activity in very hot and humid environments See Wear light clothing Hydration Fluid type Water: moderate intensity for under 1 hour Electrolyte drink: for over 1 hour Pre- : 12-20 ounces (15 min before ) During : 8 ounces fluid every 15 minutes Heat acclimatization to exertion in a warm environment Usually requires 2 to 3 weeks May be as long as 2 to 3 months for some patients Measure weight before

2018 FP Notebook

11. Personal risk factors associated with heat-related illness among new conscripts undergoing basic training in Thailand. Full Text available with Trip Pro

Personal risk factors associated with heat-related illness among new conscripts undergoing basic training in Thailand. Cases of exertional heat stroke have been reported every year during basic training for Royal Thai Army (RTA) conscripts. Prevention is an important strategy to reduce the incidence of heat-related illnesses. We conducted a study to identify potential indicators for the prevention and monitoring of heat-related illnesses among military conscripts undergoing basic training (...) in Thailand. All newly inducted RTA conscripts in 5 basic training units in 5 regions in Thailand were invited to participate in a prospective cohort study from May 1 to July 9, 2013. The incidence rate of heat-related illnesses and the incidence rate ratio (IRR) based on a Poisson regression model were used to identify the independent factors associated with heat-related illnesses, daily tympanic (body) temperatures higher than 37.5°C, >3% decreases in body weight in one day, and the production of dark

2018 PLoS ONE

12. Treatment with a heat-killed preparation of Mycobacterium vaccae after fear conditioning enhances fear extinction in the fear-potentiated startle paradigm. (Abstract)

Treatment with a heat-killed preparation of Mycobacterium vaccae after fear conditioning enhances fear extinction in the fear-potentiated startle paradigm. The hygiene hypothesis or "Old Friends" hypothesis proposes that inflammatory diseases are increasing in modern urban societies, due in part to reduced exposure to microorganisms that drive immunoregulatory circuits and a failure to terminate inappropriate inflammatory responses. Inappropriate inflammation is also emerging as a risk factor (...) for anxiety disorders, affective disorders, and trauma-and stressor-related disorders, including posttraumatic stress disorder (PTSD), which is characterized as persistent re-experiencing of the trauma after a traumatic experience. Traumatic experiences can lead to long-lasting fear memories and fear potentiation of the acoustic startle reflex. The acoustic startle reflex is an ethologically relevant reflex and can be potentiated in both humans and rats through Pavlovian conditioning. Mycobacterium vaccae

2019 Brain, behavior, and immunity

13. Novel insights into the host immune response of chicken Harderian gland tissue during Newcastle disease virus infection and heat treatment Full Text available with Trip Pro

Novel insights into the host immune response of chicken Harderian gland tissue during Newcastle disease virus infection and heat treatment Newcastle disease virus, in its most pathogenic form, threatens the livelihood of rural poultry farmers where there is a limited infrastructure and service for vaccinations to prevent outbreaks of the virus. Previously reported studies on the host response to Newcastle disease in chickens have not examined the disease under abiotic stressors, such as heat (...) , which commonly experienced by chickens in regions such as Africa. The objective of this study was to elucidate the underlying biological mechanisms that contribute to disease resistance in chickens to the Newcastle disease virus while under the effects of heat stress.Differential gene expression analysis identified genes differentially expressed between treated and non-treated birds across three time points (2, 6, and 10 days post-infection) in Fayoumi and Leghorn birds. Across the three time points

2018 BMC veterinary research

14. Heat Shock Gene Inactivation and Protein Aggregation with Links to Chronic Diseases Full Text available with Trip Pro

Heat Shock Gene Inactivation and Protein Aggregation with Links to Chronic Diseases The heat shock response involved in protein misfolding is linked to the formation of toxic immunogenic proteins with heat shock proteins (HSP) as regulators of amyloid beta aggregation. The defective amyloid beta trafficking between different intracellular compartments is now relevant to HSPs and autoimmunity. Overnutrition, temperature dysregulation, and stress repress the heat shock gene Sirtuin 1 (...) with the induction of HSP regulated amyloid beta aggregation involved in the autoimmune response. Defective circadian rhythm alterations are connected to inactivation of the peripheral sink amyloid beta clearance pathway and related to insulin resistance, protein aggregation, and autoimmune disease in non-alcoholic fatty liver disease (NAFLD) and various neurodegenerative diseases such as Alzheimer's disease. Nutritional therapy is critical to prevent immunosenescence, and plasma Sirtuin 1 levels should

2018 Diseases

15. Characteristics of Heat Illness during Hajj: A Cross-Sectional Study Full Text available with Trip Pro

treated per heat illness guidelines.Although authorities are working on research and forming interdisciplinary teams to prevent health problems during the Hajj, the mortality rate from heatstroke is high and the majority of the patients had hyperthermia, varied signs and symptoms, elevated creatinine levels, and electrolyte imbalances. (...) Characteristics of Heat Illness during Hajj: A Cross-Sectional Study Data regarding the characteristics and outcomes of heat illness are lacking in the literature. The present study aimed to identify the clinical characteristics, morbidity, management, and mortality associated with heat illness among Hajj participants.A cross-sectional study was conducted during the Hajj in 2016 on patients who presented to emergency departments and were diagnosed with heat exhaustion or heatstroke. Data were

2018 BioMed research international

16. iTRAQ-based proteomic analysis to identify the molecular mechanism of Zhibai Dihuang Granule in the Yin-deficiency-heat syndrome rats Full Text available with Trip Pro

iTRAQ-based proteomic analysis to identify the molecular mechanism of Zhibai Dihuang Granule in the Yin-deficiency-heat syndrome rats Zhibai Dihuang Granule (ZDG) is a traditional Chinese medicine which has been used to treat Yin-deficiency-heat (YDH) syndrome for thousands of years in China. However, little work has been conducted to explore the molecular mechanism of ZDG in YDH syndrome, and the processes of YDH syndrome prevention and treatment have been developed slowly. The present study (...) was aimed to explore the therapeutic mechanism of ZDG on YDH syndrome.The YDH syndrome rats were induced by hot Chinese herbs, then treated by ZDG orally for 1 week. Body weight was measured every 2 days. After sacrifice, blood samples were collected and the thymus, adrenal glands, spleen, and liver were immediately removed and weighed. iTRAQ-based proteomics approach was applied to explore the serum protein alterations with the treatment of ZDG, and to investigate the underlying mechanism of ZDG

2018 Chinese medicine

17. Evaluation of a Novel Syndromic Surveillance Query for Heat-Related Illness Using Hospital Data From Maricopa County, Arizona, 2015 Full Text available with Trip Pro

Evaluation of a Novel Syndromic Surveillance Query for Heat-Related Illness Using Hospital Data From Maricopa County, Arizona, 2015 We evaluated a novel syndromic surveillance query, developed by the Council of State and Territorial Epidemiologists (CSTE) Heat Syndrome Workgroup, for identifying heat-related illness cases in near real time, using emergency department and inpatient hospital data from Maricopa County, Arizona, in 2015.The Maricopa County Department of Public Health applied 2 (...) queries for heat-related illness to area hospital data transmitted to the National Syndromic Surveillance Program BioSense Platform: the BioSense "heat, excessive" query and the novel CSTE query. We reviewed the line lists generated by each query and used the diagnosis code and chief complaint text fields to find probable cases of heat-related illness. For each query, we calculated positive predictive values (PPVs) for heat-related illness.The CSTE query identified 674 records, of which 591 were

2017 Public Health Reports

18. Mitochondrial stress restores the heat shock response and prevents proteostasis collapse during aging Full Text available with Trip Pro

Mitochondrial stress restores the heat shock response and prevents proteostasis collapse during aging In Caenorhabditis elegans, the programmed repression of the heat shock response (HSR) accompanies the transition to reproductive maturity, leaving cells vulnerable to environmental stress and protein aggregation with age. To identify the factors driving this event, we performed an unbiased genetic screen for suppressors of stress resistance and identified the mitochondrial electron transport (...) levels of mitochondrial stress regulate cytoplasmic proteostasis and healthspan during aging by coordinating the long-term activity of HSF-1 with conditions preclusive to optimal fitness.Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

2017 Cell reports

19. Coptidis Rhizoma Prevents Heat Stress-Induced Brain Damage and Cognitive Impairment in Mice Full Text available with Trip Pro

Coptidis Rhizoma Prevents Heat Stress-Induced Brain Damage and Cognitive Impairment in Mice Heat stress conditions lead to neuroinflammation, neuronal death, and memory loss in animals. Coptidis Rhizoma (CR) exhibits potent fever-reducing effects and has been used as an important traditional medicinal herb for treating fever. However, to date, the effects of antipyretic CR on heat-induced brain damages have not been investigated. In this study, CR significantly reduced the elevation of ear (...) and rectal temperatures after exposure to heat in mice. Additionally, CR attenuated hyperthermia-induced stress responses, such as release of cortisol into the blood, and upregulation of heat shock protein and c-Fos in the hypothalamus and hippocampus of mice. The administration of CR inhibited gliosis and neuronal loss induced by thermal stress in the hippocampal CA3 region. Treatment with CR also reduced the heat stress-induced expression of nuclear factor kappa β, tumor necrosis factor-α

2017 Nutrients

20. Heated Humidified High-Flow Nasal Cannula for Prevention of Extubation Failure in Preterm Infants. (Abstract)

Heated Humidified High-Flow Nasal Cannula for Prevention of Extubation Failure in Preterm Infants. To compare extubation failure rate between the heated humidified high-flow nasal cannula (HHHFNC) and continuous positive airway pressure (CPAP) groups.Intubated infants with gestational age (GA) <32 wk, who were ready to extubate, were randomized to receive respiratory support with either CPAP or HHHFNC after extubation. In CPAP group, nasal mask CPAP with preset pressure and fraction of inspired (...) oxygen (FiO2) equal to positive end-expiratory pressure (PEEP) and FiO2 of ventilator before extubation was applied. In the HHHFNC group, predefined flow rate according to the protocol was applied. Primary outcome was extubation failure within 72 h after endotracheal tube removal.Forty-nine infants were enrolled; 24 in the HHHFNC and 25 in the CPAP group. Baseline demographic and respiratory conditions before extubation were similar. There was no difference in infants who met failed extubation

2017 Indian journal of pediatrics Controlled trial quality: uncertain

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