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Heart Transplant

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1. Artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure

to transplantation'). In this procedure, the device replaces the heart function completely. 3.2 Implantation of a TAH is done with the patient under general anaesthesia and on cardiopulmonary bypass. The native left and right ventricles, and all 4 cardiac valves are excised. The TAH device is implanted and attached to the atria, for blood inflow, and pulmonary artery and aorta, for blood outflow. Depending on the type of TAH, power is supplied either by drive lines connected percutaneously to an external (...) ) compared with 30% (111/366), p=0.9 after transplantation. The causes of death while on device support (infection, multi-organ failure, stroke or haemorrhage) and after heart transplantation (acute rejection, infection, cardiac arrest, multi-organ failure and stroke) for both groups were also similar. In a non-randomised prospective comparative study of 130 patients, rates of death before transplantation were 21% (17/81) in the TAH group compared with 54% (19/35) in the control group (p value

2018 National Institute for Health and Clinical Excellence - Interventional Procedures

2. Exercise-based cardiac rehabilitation in heart transplant recipients. Full Text available with Trip Pro

Exercise-based cardiac rehabilitation in heart transplant recipients. Heart transplantation is considered to be the gold standard treatment for selected patients with end-stage heart disease when medical therapy has been unable to halt progression of the underlying pathology. Evidence suggests that aerobic exercise training may be effective in reversing the pathophysiological consequences associated with cardiac denervation and prevent immunosuppression-induced adverse effects in heart (...) cardiac rehabilitation improves exercise capacity, but exercise was found to have no impact on health-related quality of life in the short-term (median 12 weeks follow-up), in heart transplant recipients whose health is stable.There was no evidence of statistical heterogeneity across trials for exercise capacity and no evidence of small study bias. The overall risk of bias in included studies was judged as low or unclear; more than 50% of included studies were assessed at unclear risk of bias

2017 Cochrane

3. 2017 ACC/AHA/HFSA/ISHLT/ACP Advanced Training Statement on Advanced Heart Failure and Transplant Cardiology (Revision of the ACCF/AHA/ACP/HFSA/ISHLT 2010 Clinical Competence Statement on Management of Patients With Advanced Heart Failure and Cardiac Trans

2017 ACC/AHA/HFSA/ISHLT/ACP Advanced Training Statement on Advanced Heart Failure and Transplant Cardiology (Revision of the ACCF/AHA/ACP/HFSA/ISHLT 2010 Clinical Competence Statement on Management of Patients With Advanced Heart Failure and Cardiac Trans 2017 Advanced Training Statement on Advanced Heart Failure and Transplant Cardiology - American College of Cardiology ') ') } Search All Types Search or Menu Share via: Print Font Size A A A Authors: Jessup M, Drazner MH, Book W, et al (...) . Citation: The following are key points to remember about this revised Advanced Training Statement on Advanced Heart Failure and Transplant Cardiology (AHFTC): This Advanced Training Statement addresses the added competencies required of subspecialists in AHFTC for diagnosis and management at a high level of skill of patients with heart failure who may also undergo placement of mechanical circulatory support (MCS) devices or cardiac transplantation. The training is intended to complement the basic

2017 American Heart Association

4. American Association for Thoracic Surgery/International Society for Heart and Lung Transplantation guidelines on selected topics in mechanical circulatory support

American Association for Thoracic Surgery/International Society for Heart and Lung Transplantation guidelines on selected topics in mechanical circulatory support American Association for Thoracic Surgery/International Society for Heart and Lung Transplantation guidelines on selected topics in mechanical circulatory support - The Journal of Heart and Lung Transplantation Email/Username: Password: Remember me Search Terms Search within Search Volume 39, Issue 3, Pages 187–219 To read (...) this article in full, please review your options for gaining access at the bottom of the page. American Association for Thoracic Surgery/International Society for Heart and Lung Transplantation guidelines on selected topics in mechanical circulatory support Editors , x James K. Kirklin Affiliations Department of Surgery, University of Alabama at Birmingham, Birmingham, Ala Correspondence Reprint Requests: James K. Kirklin, MD, Department of Surgery, The University of Alabama at Birmingham, ZRB 721, 1900

2020 International Society for Heart and Lung Transplantation

5. ISHLT Consensus Statement on Donor Organ Acceptability and Management in Pediatric Heart Transplantation Full Text available with Trip Pro

, O'Brien, KD, Dardas, T et al. Systematic donor selection review process improves cardiac transplant volumes and outcomes. J Thorac Cardiovasc Surg . 2016 ; 151 : 238–243 , x 16 Morrison, AK, Gowda, C, Tumin, D et al. Pediatric marginal donor hearts: trends in US national use, 2005-2014. Pediatr Transplant . 2018 ; 22 : e13216 As part of this project, a survey was sent to 12 OPOs, of which 5 responded, representing 245 million people ( Table 1 ), and their discard rate ranged from 18% to 57%. Reasons (...) time. J Heart Lung Transplant . 2017 ; 36 : 1060–1069 Analysis of the UNOS database showed that there is some evidence that there is a difference in mortality and the development of cardiac allograft vasculopathy, especially in adolescents who receive a donor organ >5 years older than their chronological age, especially if the donor is >25 years of age. x 21 Westbrook, TC, Morales, DLS, Khan, MS et al. Interaction of older donor age and survival after weight-matched pediatric heart transplantation

2020 International Society for Heart and Lung Transplantation

6. 2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists

of selected AHFTC specialists on the basis of background, specialized knowledge, skills, experience, and practice focus (right column). This distinction is particularly relevant to the patient care competencies and recognizes diversity in the focus of practice of AHFTC specialists. Some physicians may specialize in a particular aspect of AHFTC, such as mechanical circulatory support or cardiac transplantation, while others may adopt a practice focused on patients with chronic heart failure with a lesser (...) , there is a growing subspecialization career focus within AHFTC. Specifically, some practitioners limit the scope of their clinical activity to treating patients with advanced heart failure, including those who undergo implantation of a durable ventricular assist device or cardiac transplantation, while others focus on disease management of patients with less advanced heart failure. Thus, although maintenance of some AHFTC competencies is an expectation for all clinical AHFTC specialists, the maintenance

2020 International Society for Heart and Lung Transplantation

11. The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: A 10-year update

on the predictability of peak VO 2 on adverse cardiac events. 2 A more recent retrospective study evaluated the predict- ability of peak VO 2 in patients undergoing evaluation for heart transplantation (HT) with an implantable cardioverter de?brillator (ICD), CRT, or both (CRT-D) devices. This studysuggestedthatapeakVO 2 r10ml/kg/minratherthan the traditional cutoff value ofr 14 ml/kg/min may be more useful for risk strati?cation in the device era. 3 At this time, we feel that using currently accepted peak VO 2 (...) of diagnostic right-heart catheterization Right heart catheterization (RHC) should be performed on all candidates in preparation for listing for cardiac transplantation and annually until transplantation (Class 1, Level of Evidence: C). Right heart catheterization (RHC) should be performed on all adult candidates in preparation for listing for cardiac transplantation and periodically until transplantation (Class 1, Level of Evidence: C). Periodic RHC is not advocated for routine surveillance in children

2016 International Society for Heart and Lung Transplantation

12. Recurrent Cardiac Myxoma Treated by Orthotopic Heart Transplantation: A Case Report and Literature Review of Heart Transplantation for Primary Cardiac Tumor Full Text available with Trip Pro

Recurrent Cardiac Myxoma Treated by Orthotopic Heart Transplantation: A Case Report and Literature Review of Heart Transplantation for Primary Cardiac Tumor Primary cardiac myxoma is the most common primary cardiac tumor. Tumor resection is the treatment of choice and overall long-term prognosis is good and recurrence is rare. This report presents a case of a young girl who presented with multiple recurrent cardiac myxoma. She underwent 3 sternotomy surgeries of 3 separated episodes of cardiac (...) myxoma resection. On the fourth recurrence, the patient underwent orthotopic heart transplant. The patient tolerated the procedure well and is alive 6 months after the procedure with NYHA class I. We reviewed evidences and summarized reported cases of orthotopic heart transplant operation for primary cardiac tumor in the literature.

2018 Case reports in transplantation

13. A decade of pediatric mechanical circulatory support before and after cardiac transplantation

A decade of pediatric mechanical circulatory support before and after cardiac transplantation PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2017 PedsCCM Evidence-Based Journal Club

14. The management of antibodies in heart transplantation: An ISHLT consensus document Full Text available with Trip Pro

The management of antibodies in heart transplantation: An ISHLT consensus document The management of antibodies in heart transplantation: An ISHLT consensus document - The Journal of Heart and Lung Transplantation Email/Username: Password: Remember me Search Terms Search within Search Volume 37, Issue 5, Pages 537–547 To read this article in full, please review your options for gaining access at the bottom of the page. The management of antibodies in heart transplantation: An ISHLT consensus (...) , Germany , MD d , x Maria G. Crespo-Leiro Affiliations Heart Failure and Heart Transplant Program, Hospital Universitario A Coruña, Coruña, Spain , MD, PhD e , x Juan F. Delgado Affiliations Cardiology Department, Hospital Universitario 12 de Octubre, Madrid, Spain , MD f , x Michael Olymbios Affiliations Advanced Heart Disease Section, Cedars-Sinai Heart Institute, Los Angeles, California, USA , MBBS a , x Jayan Parameshwar Affiliations Cardiology, Papworth Hospital, Cambridge, UK , MD g , x Jignesh

2018 International Society for Heart and Lung Transplantation

15. Delayed autologous stem cell transplantation following cardiac transplantation experience in patients with cardiac amyloidosis. (Abstract)

Delayed autologous stem cell transplantation following cardiac transplantation experience in patients with cardiac amyloidosis. This study sought to retrospectively investigate the outcomes of patients with light-chain amyloidosis (AL) with advanced cardiac involvement who were treated with a strategy of heart transplantation (HT) followed by delayed autologous stem cell transplantation (ASCT) at 1-year posttransplant. Patients with AL amyloidosis with substantial cardiac involvement have (...) traditionally had very poor survival (eg, several months). A few select centers have reported their outcomes for HT followed by a strategy of early ASCT (ie, 6 months) for CA. The outcomes of patients undergoing a delayed strategy have not been reported. All patients with AL amyloidosis at a single institution undergoing evaluation for HT from 2004-2018 were included. Retrospective analyses were performed. Sixteen patients underwent HT (including two combined heart-kidney transplant) for AL amyloidosis

2019 American Journal of Transplantation

16. Children's Heart Assessment Tool for Transplantation (CHAT) Score: A Novel Risk Score Predicts Survival After Pediatric Heart Transplantation. (Abstract)

Children's Heart Assessment Tool for Transplantation (CHAT) Score: A Novel Risk Score Predicts Survival After Pediatric Heart Transplantation. Given the shortage of donor organs in pediatric heart transplantation (HTx), pretransplant risk stratification may assist in organ allocation and recipient optimization. We sought to construct a scoring system to preoperatively stratify a patient's risk of one-year mortality after HTx.The United Network for Organ Sharing database was queried (...) -12.35; P < .001) scores were associated with an increased risk of one-year mortality when compared to the low-risk group.The Children's Heart Assessment Tool for Transplantation score represents a pediatric-specific, recipient-based system to predict one-year mortality after HTx. Its use could assist providers in identification of patients at highest risk of poor outcomes and may aid in pretransplant optimization of these children.

2019 World journal for pediatric & congenital heart surgery Controlled trial quality: uncertain

17. Haemodynamic effects of percutaneous mitral valve edge‐to‐edge repair in patients with end‐stage heart failure awaiting heart transplantation Full Text available with Trip Pro

Haemodynamic effects of percutaneous mitral valve edge‐to‐edge repair in patients with end‐stage heart failure awaiting heart transplantation Functional mitral regurgitation is complicating end-stage heart failure and potential heart transplantation by increasing pulmonary artery pressures. The aim of the present study was to investigate feasibility and haemodynamic effects of percutaneous mitral valve edge-to-edge repair using the MitraClip™ device in patients with end-stage heart (...) failure awaiting heart transplantation.In this retrospective study, we identified nine patients suffering from end-stage heart failure listed for heart transplantation in whom moderate-severe or severe functional mitral regurgitation was recognized and treated with percutaneous mitral valve edge-to-edge repair. Twenty-two patients listed for heart transplantation and presenting with moderate-severe or severe functional mitral regurgitation treated in the pre-MitraClip™ era served as controls. Patients

2018 ESC heart failure

18. Transvenous dual‐chamber pacemaker after paediatric heart transplantation using left ventricle pacing through the coronary sinus Full Text available with Trip Pro

Transvenous dual‐chamber pacemaker after paediatric heart transplantation using left ventricle pacing through the coronary sinus A 12-year-old child with end-stage heart failure due to restrictive cardiomyopathy was submitted to orthotopic heart transplantation. Primary graft dysfunction required venous arterial extra-corporeal membrane oxygenation. Heart function normalized, but complete atrioventricular block remained after 3 weeks. A dual-chamber pacing with transvenous left ventricle (...) pacing through the coronary sinus was performed. At 5-year follow-up, the patient is stable with the same pacing system and with preserved ventricular function.© 2018 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology.

2018 ESC heart failure

19. Subcutaneous implantable cardioverter defibrillator in patients awaiting cardiac transplantation or left ventricular assist device for refractory heart failure: a feasible alternative to transvenous device? Full Text available with Trip Pro

Subcutaneous implantable cardioverter defibrillator in patients awaiting cardiac transplantation or left ventricular assist device for refractory heart failure: a feasible alternative to transvenous device? 29377556 2018 12 17 2018 12 17 2055-5822 5 3 2018 06 ESC heart failure ESC Heart Fail Subcutaneous implantable cardioverter defibrillator in patients awaiting cardiac transplantation or left ventricular assist device for refractory heart failure: a feasible alternative to transvenous device (...) of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy. Gerosa Gino G Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy. Iliceto Sabino S Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy. eng Editorial 2018 01 27 England ESC Heart Fail 101669191 2055-5822 IM Defibrillators, Implantable Feasibility Studies Heart Failure surgery Heart Transplantation Heart-Assist Devices Humans Subcutaneous Tissue Waiting

2018 ESC heart failure

20. Normothermic extracorporeal preservation of hearts for transplantation following donation after brainstem death

agents. Invasive therapies include electrophysiological interventions, such as pacemakers and implantable cardioverter defibrillators, revascularisation by percutaneous coronary angioplasty and stenting or coronary artery bypass grafting, valve replacement or repair, and temporary use of intra-aortic balloon pumps. 2.3 In chronic heart failure, conventional treatment strategies may not work, resulting in the need for heart transplantation or implantation of a ventricular assist device to provide (...) , coronary flow, blood temperature and heart rate are all monitored. Immediately before the transplantation procedure, the heart is arrested with cold cardioplegia solution and disconnected from the perfusion machine. It is then implanted into the recipient. This procedure has been used to store donor hearts for up to 8 hours before transplantation. 4 4 Efficacy Efficacy This section describes efficacy outcomes from the published literature that the Committee considered as part of the evidence about

2016 National Institute for Health and Clinical Excellence - Interventional Procedures

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