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Heart Disease in Women

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1. Primary prevention of coronary heart disease in women

Primary prevention of coronary heart disease in women Primary prevention of coronary heart disease in women | British Menopause Society Search for: Summary consensus statement Primary prevention of coronary heart disease in women Primary prevention of coronary heart disease in women 2019-05-14T15:17:51+01:00 Summary Coronary heart disease (CHD) is a leading cause of death in women. Observational studies have consistently shown oestrogen to help prevent CHD in postmenopausal women. The large (...) randomized controlled Women’s Health Initiative (WHI) trial initially did not confirm these observational findings. However, further analyses of the WHI study as well as meta-analyses of randomised clinical trials of hormone replacement therapy (HRT) and of the observational Nurses’ Health Study have now found that the timing of onset of HRT use is important and that oestrogen may have an important protective role in CHD, particularly in women initiating treatment below age 60 years. This consensus

2019 British Menopause Society

2. Promoting Risk Identification and Reduction of Cardiovascular Disease in Women Through Collaboration With Obstetricians and Gynecologists: A Presidential Advisory From the American Heart Association and the American College of Obstetricians and Gynecologi

Promoting Risk Identification and Reduction of Cardiovascular Disease in Women Through Collaboration With Obstetricians and Gynecologists: A Presidential Advisory From the American Heart Association and the American College of Obstetricians and Gynecologi Promoting Risk Identification and Reduction of Cardiovascular Disease in Women Through Collaboration With Obstetricians and Gynecologists: A Presidential Advisory From the American Heart Association and the American College of Obstetricians (...) have been seen over the past 2 decades, in part as a result of initiatives such as the American Heart Association’s (AHA’s) Go Red For Women movement. Go Red For Women initially focused on raising awareness of heart disease as the No. 1 killer of women. This campaign expanded gender-focused research and the development of gender-based guidelines that led to a significant reduction in the rates of death among women. Despite these advances, gender-based inequalities continue, with women being less

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2018 American Heart Association

3. Psychological traits, heart rate variability, and risk of coronary heart disease in healthy aging women - the Women's Health Initiative. (PubMed)

Psychological traits, heart rate variability, and risk of coronary heart disease in healthy aging women - the Women's Health Initiative. Psychological traits such as optimism and hostility affect coronary heart disease (CHD) risk, but mechanisms for this association are unclear. We hypothesized that optimism and hostility may affect CHD risk via changes in heart rate variability (HRV).We conducted a longitudinal analysis using data from the Women's Health Initiative Myocardial Ischemia (...) and Migraine Study. Participants underwent 24-hour ambulatory ECG monitoring 3 years after enrollment. Optimism (Life Orientation Test-Revised), cynical hostility (Cook-Medley), demographics, and coronary risk factors were assessed at baseline. HRV measures included standard deviation of average N-N intervals (SDNN); standard deviation of average N-N intervals over 5 min (SDANN); and average heart rate (HR). CHD - was defined as the first occurrence of myocardial infarction, angina, coronary angioplasty

2019 Psychosomatic Medicine

4. Cohort study: Late-life increases in alcohol consumption among postmenopausal women appear associated with greater breast cancer risk and less coronary heart disease risk

Cohort study: Late-life increases in alcohol consumption among postmenopausal women appear associated with greater breast cancer risk and less coronary heart disease risk Late-life increases in alcohol consumption among postmenopausal women appear associated with greater breast cancer risk and less coronary heart disease risk | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser (...) women appear associated with greater breast cancer risk and less coronary heart disease risk Article Text Aetiology/harm Cohort study Late-life increases in alcohol consumption among postmenopausal women appear associated with greater breast cancer risk and less coronary heart disease risk Tim R Stockwell 1 , Tanya N Chikritzhs 2 Statistics from Altmetric.com Commentary on: Dam M , Hvidtfeldt U , Tjønneland A , et al . Five year change in alcohol intake and risk of breast cancer and coronary heart

2016 Evidence-Based Medicine (Requires free registration)

5. Personality traits and the risk of coronary heart disease or stroke in women with diabetes - an epidemiological study based on the Women's Health Initiative. (PubMed)

Personality traits and the risk of coronary heart disease or stroke in women with diabetes - an epidemiological study based on the Women's Health Initiative. We studied the associations between personality traits and the risk of coronary heart disease (CHD) or stroke in women with diabetes.From the Women's Health Initiative, 15,029 women aged 50 to 79 years at enrollment and with self-reported treated diabetes at baseline or follow-up, were followed for a mean of 10 years. Personality traits (...) , and lifestyle factors.A total of 1,118 incident CHD and 710 incident stroke cases were observed. Women in the highest quartile of hostility had 22% (hazard ratio [HR] 1.22, 95% confidence interval [CI] 1.01-1.48) increased risk for CHD compared with women in the lowest quartile of hostility. P values for trend were greater than 0.05. Stratified analysis by prevalent or incident diabetes showed that the highest quartile of hostility had 34% increased risk for CHD (HR 1.34, 95% CI 1.03-1.74) among women

2019 Menopause

6. Peer Support for Women With Heart Disease: Women@Heart

Peer Support for Women With Heart Disease: Women@Heart Peer Support for Women With Heart Disease: Women@Heart - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Peer Support for Women With Heart Disease: Women (...) Information provided by (Responsible Party): Dr Robert Reid, Ottawa Heart Institute Research Corporation Study Details Study Description Go to Brief Summary: Women with heart disease are more likely to die or suffer another cardiac event or stroke within 5 years of an index event compared to men. They are also more likely to suffer depression and report lower quality of life. Cardiac Rehabilitation programs have been designed to address these issues, but most women do not attend. Women indicate they have

2017 Clinical Trials

7. Fatty Liver Disease, Women, and Aldosterone: Finding a Link in the Jackson Heart Study (PubMed)

Fatty Liver Disease, Women, and Aldosterone: Finding a Link in the Jackson Heart Study Fatty liver disease is one of the most common forms of chronic liver disease. The renin-angiotensin-aldosterone system has been implicated in the pathogenesis of fatty liver.Determine the relationship between fatty liver and aldosterone in a large cohort study.Community-based, observational cohort study of African Americans.The original Jackson Heart Study cohort enrolled African American participants from (...) the Jackson, Mississippi, metropolitan area in Hinds, Madison, and Rankin Counties.Our study population consisted of 2507 Jackson Heart Study participants (1625 women and 882 men) who had liver attenuation measured per computed tomography scans, had aldosterone measurements, and were not taking angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, or mineralocorticoid receptor antagonists.There was no intervention.Liver attenuation on computed tomography scans.Univariate regression

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2017 Journal of the Endocrine Society

8. Maternal and Fetal Outcomes of Admission for Delivery in Women With Congenital Heart Disease (PubMed)

Maternal and Fetal Outcomes of Admission for Delivery in Women With Congenital Heart Disease Women with congenital heart disease (CHD) may be at increased risk for adverse events during pregnancy and delivery.To compare delivery outcomes between women with and without CHD.This retrospective study of inpatient delivery admissions in the Healthcare Cost and Utilization Project's California State Inpatient Database compared maternal and fetal outcomes between women with and without CHD by using (...) multivariate logistic regression. Female patients with codes for delivery from the International Classification of Diseases, Ninth Revision, from January 1, 2005, through December 31, 2011, were included. The association of CHD with readmission was assessed to 7 years after delivery. Cardiovascular morbidity and mortality were hypothesized to be higher among women with CHD. Data were analyzed from April 4, 2014, through January 23, 2017.Noncomplex and complex CHD.Maternal outcomes included in-hospital

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2017 JAMA cardiology

9. Neuropsychological effects in women with a coronary heart disease: a systematic review

Neuropsychological effects in women with a coronary heart disease: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites (...) of outcome assessment reported (stratified yes vs no). For stratified analyses, a minimum number of 8 studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease models, the decision to pool certain units of measurement for an outcome, the choice of effect measure, how

2019 PROSPERO

10. Overt and Covert Anxiety as a Toxic Factor in Ischemic Heart Disease in Women: The Link Between Psychological Factors and Heart Disease (PubMed)

Overt and Covert Anxiety as a Toxic Factor in Ischemic Heart Disease in Women: The Link Between Psychological Factors and Heart Disease BACKGROUND Long-term clinical observations have shown that anxiety disorders influence the etiopathogenesis of ischemic heart disease (IHD) in women. The aim of this study was to determine the characteristics of the structure of overt and covert anxiety, and to examine the impact of the severity of anxiety on five personality traits as described Costa (...) and McCrae. MATERIAL AND METHODS The study involved 50 women aged 37 to 74 years, who were treated because of IHD that was confirmed by angiographic examination of the coronary vessels. Psychological studies were conducted using the IPAT Anxiety Scale (Cattell) and NEO-FFI Personality Inventory (Costa and McCrae). RESULTS From among the 50 women with IHD included in the study, 28 had higher overt anxiety scores than covert anxiety scores. Women with high overt anxiety were more emotionally changeable (C

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2017 Medical science monitor : international medical journal of experimental and clinical research

11. Sudden Cardiac Death in Women With Suspected Ischemic Heart Disease, Preserved Ejection Fraction, and No Obstructive Coronary Artery Disease: A Report From the Women's Ischemia Syndrome Evaluation Study (PubMed)

Sudden Cardiac Death in Women With Suspected Ischemic Heart Disease, Preserved Ejection Fraction, and No Obstructive Coronary Artery Disease: A Report From the Women's Ischemia Syndrome Evaluation Study Sudden cardiac death (SCD) is often the first presentation of ischemic heart disease; however, there is limited information on SCD among women with and without obstructive coronary artery disease (CAD). We evaluated SCD incidence in the WISE (Women's Ischemia Syndrome Evaluation) study.Overall (...) , 904 women with suspected ischemic heart disease with preserved ejection fraction and core laboratory coronary angiography were followed for outcomes. In case of death, a death certificate and/or a physician or family narrative of the circumstances of death was obtained. A clinical events committee rated all deaths as cardiovascular or noncardiovascular and as SCD or non-SCD. In total, 96 women (11%) died over a median of 6 years (maximum: 8 years). Among 65 cardiovascular deaths, 42% were SCD

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2017 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

12. Lower DHEA-S levels predict disease and worse outcomes in post-menopausal women with idiopathic, connective tissue disease- and congenital heart disease-associated pulmonary arterial hypertension. (PubMed)

Lower DHEA-S levels predict disease and worse outcomes in post-menopausal women with idiopathic, connective tissue disease- and congenital heart disease-associated pulmonary arterial hypertension. High oestradiol (E2) and low dehydroepiandrosterone-sulfate (DHEA-S) levels are risk factors for pulmonary arterial hypertension (PAH) in men, but whether sex hormones are related to PAH in women is unknown.Post-menopausal women aged ≥55 years with PAH were matched by age and body mass index to women (...) without cardiovascular disease. Plasma sex hormone levels were measured by immunoassay.Lower levels of DHEA-S (p<0.001) and higher levels of E2 (p=0.02) were associated with PAH. In PAH cases (n=112), lower DHEA-S levels were associated with worse haemodynamics (all p<0.01) and more right ventricular dilatation and dysfunction (both p=0.001). Lower DHEA-S levels were associated with shorter 6-min walking distance (6MWD) (p=0.01) and worse functional class (p=0.004). Each Ln(1 µg·dL-1) decrease in DHEA

2018 European Respiratory Journal

13. Biological versus mechanical heart valve prosthesis during pregnancy in women with congenital heart disease. (PubMed)

Biological versus mechanical heart valve prosthesis during pregnancy in women with congenital heart disease. We evaluate pregnancy outcome and anticoagulation regimes in women with mechanical and biological prosthetic heart valves (PHV) for congenital heart disease.Retrospective multicenter cohort studying pregnancy outcomes in an existing cohort of patients with PHV.52 women had 102 pregnancies of which 78 pregnancies (46 women) ≥20 weeks duration (59 biological, 19 mechanical PHV (...) ). Miscarriages (n = 19, ≤20 weeks) occurred more frequently in women using anticoagulation (P < .05). During 42% of pregnancies of women with mechanical PHV a combined low molecular weight heparin (LMWH) vitamin-K-antagonist anticoagulation regime was used (n = 8). Overall, cardiovascular, obstetric and fetal/neonatal complications occurred in 17% (n = 13), 68% (n = 42) and 42% (n = 27) of the pregnancies. Women with mechanical PHV had significantly higher cardiovascular (12% vs 32%, P < .05), obstetric (59

2018 International journal of cardiology

14. Long-term mortality and estimated functional capacity among women with symptoms of ischemic heart disease: From the NHLBI-sponsored Women's Ischemia Syndrome Evaluation. (PubMed)

Long-term mortality and estimated functional capacity among women with symptoms of ischemic heart disease: From the NHLBI-sponsored Women's Ischemia Syndrome Evaluation. The aim of this study was to determine the long-term prognostic value of the Duke Activity Status Index-estimated metabolic equivalents (METs) values among women with suspected ischemic heart disease. At a median of 9.6 years, the incidence of death was 23.4% in those with METs <4.8 versus 8.2% in METs >9.9, P < .01 (...) . In conclusion, use of the simple, patient-reported Duke Activity Status Index could help identify higher-risk women with suspected ischemic heart disease for targeted risk management.Copyright © 2018 Elsevier Inc. All rights reserved.

2018 American Heart Journal

15. [Application of sevoflurane and laryngeal mask in cesarean section in women with heart disease]. (PubMed)

[Application of sevoflurane and laryngeal mask in cesarean section in women with heart disease]. To compare the safety of sevoflurane anesthesia with laryngeal mask and tracheal intubation in cesarean section in women with heart disease.Fifty-two pregnant women with heart diseases undergoing cesarean section were randomized into laryngeal mask (LAM) group and tracheal intubation group. In LAM group, 6% sevoflurane was given at the rate of 6 L/min for induction with a maintenance sevoflurane (...) section in women with heart disease.

2019 Nan fang yi ke da xue xue bao = Journal of Southern Medical University

16. Artificially Sweetened Beverages and Stroke, Coronary Heart Disease, and All-Cause Mortality in the Women's Health Initiative. (PubMed)

Artificially Sweetened Beverages and Stroke, Coronary Heart Disease, and All-Cause Mortality in the Women's Health Initiative. Background and Purpose- We examine the association between self-reported consumption of artificially sweetened beverages (ASB) and stroke and its subtypes, coronary heart disease, and all-cause mortality in a cohort of postmenopausal US women. Methods- The analytic cohort included 81 714 women from the Women's Health Initiative Observational Study, a multicenter (...) to never or rarely (<1/wk) had significantly greater likelihood of all end points (except hemorrhagic stroke), after controlling for multiple covariates. Adjusted models indicated that hazard ratios and 95% confidence intervals were 1.23 (1.02-1.47) for all stroke; 1.31 (1.06-1.63) for ischemic stroke; 1.29 (1.11-1.51) for coronary heart disease; and 1.16 (1.07-1.26) for all-cause mortality. In women with no prior history of cardiovascular disease or diabetes mellitus, high consumption of ASB

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2019 Stroke

17. Pregnancy in women with pre-existent ischaemic heart disease: a systematic review with individualised patient data. (PubMed)

Pregnancy in women with pre-existent ischaemic heart disease: a systematic review with individualised patient data. Studies on pregnancy risk in women with ischaemic heart disease (IHD) have mainly excluded pregnancies in women with pre-existent IHD. There is a need for better information about the pregnancy risks in these women and their offspring.We performed a systematic review searching the PubMed/MEDLINE public database for pregnancy in women with pre-existent IHD analysing the cardiac (...) and fetal/neonatal complications in 42% (n=47).Pregnancies in women with pre-existing IHD are high-risk pregnancies. These women have a high risk of ischaemic cardiovascular complications including 2% maternal mortality. The risk of ischaemic complications is especially high among women with atherosclerotic coronary artery disease.© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

2019 Heart

18. Menopausal symptoms and risk of coronary heart disease in middle-aged women: A nationwide population-based cohort study. (PubMed)

Menopausal symptoms and risk of coronary heart disease in middle-aged women: A nationwide population-based cohort study. To assess the relationship between coronary heart disease (CHD) and menopausal symptoms in middle-aged women in Taiwan.The present study identified 14,340 symptomatic menopausal women without a history of CHD from the Taiwan National Health Insurance Research Database from January 1, 2000, to December 31, 2013. A total of 14,340 age- and Charlson-comorbidity-index-score (...) -matched asymptomatic women were used as controls. Possible comorbidity-attributable risks of CHD were surveyed to assess whether the symptomatic menopausal cohort had a higher incidence of CHD.The incidence of CHD was higher in the symptomatic menopausal cohort than in the control cohort (17.18 vs. 12.05 per 1000 person-years). After adjustment in multivariate Cox analysis, the risk of CHD was significantly higher in the symptomatic menopausal cohort (adjusted hazard ratio = 1.344, 95% confidence

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2018 PLoS ONE

19. Maternal Comorbidities and Complications of Delivery in Pregnant Women With Congenital Heart Disease. (PubMed)

Maternal Comorbidities and Complications of Delivery in Pregnant Women With Congenital Heart Disease. Pregnant women with congenital heart defects (CHDs) may be at increased risk for adverse events during delivery.This study sought to compare comorbidities and adverse cardiovascular, obstetric, and fetal events during delivery between pregnant women with and without CHDs in the United States.Comorbidities and adverse delivery events in women with and without CHDs were compared in 22,881,691 (...) to 238.0), congestive heart failure (aOR: 49.1; 95% CI: 37.4 to 64.3), and coronary artery disease (aOR: 31.7; 95% CI: 21.4 to 47.0). Greater odds of adverse events were observed, including heart failure (aOR: 22.6; 95% CI: 20.5 to 37.3), arrhythmias (aOR: 12.4; 95% CI: 11.0 to 14.0), thromboembolic events (aOR: 2.4; 95% CI: 2.0 to 2.9), pre-eclampsia (aOR: 1.5; 95% CI: 1.3 to 1.7), and placenta previa (aOR: 1.5; 95% CI: 1.2 to 1.8). Cesarean section, induction, and operative vaginal delivery were more

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2019 Journal of the American College of Cardiology

20. Exploratory analysis of traditional risk factors of ischemic heart disease (IHD) among predominantly Malay Malaysian women. (PubMed)

Exploratory analysis of traditional risk factors of ischemic heart disease (IHD) among predominantly Malay Malaysian women. The risk factors of ischemic heart disease (IHD) specific for women are less well studied. However, knowing the risk factors of IHD for women will empower women themselves to be better informed and thus can help them in decision making concerning their health condition. The objective of this study is to explore the commonly studied risk factors of ischemic heart disease (...) (IHD) among a group of Malaysian women.A case control study was conducted among 142 newly diagnosed IHD women patients registered in government hospitals in Terengganu, Malaysia and their 1:1 frequency matched population controls. Data on sociodemographic and socioeconomic profile, co-morbidities, lifestyle factors related to physical activities, dietary fat intake, stress, passive smoking history, anthropometric measurements and biochemical markers were obtained.Middle aged women were recruited

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2019 BMC Public Health

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