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1. Effectiveness of tapering from methadone or buprenorphine maintenance treatment compared to traditional maintenance treatment for people with opiate addiction: systematic review

Effectiveness of tapering from methadone or buprenorphine maintenance treatment compared to traditional maintenance treatment for people with opiate addiction: systematic review Effectiveness of tapering from methadone or buprenorphine maintenance treatment compared to traditional maintenance treatment for people with opiate addiction: systematic review - NIPH Selected items added to basket Close Search for: Søk Meny Infectious diseases & Vaccines Close Mental & Physical health Close (...) Environment & Lifestyle Close Health in Norway Close Quality & Knowledge Close Research & Access to data Close About NIPH Close Effectiveness of tapering from methadone or buprenorphine maintenance treatment compared to traditional maintenance treatment for people with opiate addiction: systematic review Have you found an error? Order Download: Key message In Norway we offer opioid maintenance treatment with methadone or buprenorphine for people with opioid dependence. For most people who use methadone

2017 Norwegian Institute of Public Health

2. Olaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer

Olaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer Overview | Olaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer | Guidance | NICE Olaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer Technology appraisal guidance [TA620] Published date: 15 January 2020 Share Save Guidance on olaparib (Lynparza) for maintenance (...) then. Commercial arrangement There is a simple discount patient access scheme and a commercial access agreement for olaparib. These form part of the . Contact for details. Guidance development process This guidance updates and replaces NICE technology appraisal guidance 381 Your responsibility The recommendations in this guidance represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, health professionals are expected to take this guidance

2020 National Institute for Health and Clinical Excellence - Technology Appraisals

3. Prevalence and Safety of Intravenous Immunoglobulin Administration During Maintenance Chemotherapy in Children with Acute Lymphoblastic Leukemia in First Complete Remission: A Health Maintenance Organization Perspective Full Text available with Trip Pro

Prevalence and Safety of Intravenous Immunoglobulin Administration During Maintenance Chemotherapy in Children with Acute Lymphoblastic Leukemia in First Complete Remission: A Health Maintenance Organization Perspective Children with acute lymphoblastic leukemia (ALL) in first complete remission (CR1) experience hypogammaglobulinemia and are at risk of sepsis during maintenance chemotherapy. Intravenous immunoglobulin (IVIG) has been used to try to circumvent this risk, but no data exist (...) regarding its safety and prevalence in a health maintenance organization.To evaluate the prevalence and safety of IVIG in children with ALL in CR1 during maintenance chemotherapy.A multicenter, retrospective cohort study of consecutive children with ALL in CR1 during maintenance chemotherapy from 2008 to 2014. Groups treated with or without IVIG were compared using nonparametric statistics. Multivariate logistic regression involved all variables available before maintenance therapy began.One hundred

2018 The Permanente journal

4. [Survey of periodontal health in medical college students after 3 years of periodontal health maintenance]. (Abstract)

[Survey of periodontal health in medical college students after 3 years of periodontal health maintenance]. To observe and evaluate the status of periodontal disease in young people and the effect of intervention to control the development of periodontal diseases.One hundred and fifty-three medical college students were randomly divided into group A (receiving interventions) and group B (no interventions). They were followed up for 3 years. The subjects in group A received oral health education (...) , including selection of the toothbrush, the right way to brush teeth, the use of dental floss and interdental brush. At the same time ,they were given initial periodontal treatment according to the actual situation, and received oral health education, periodontal maintenance treatment, and reinforced plaque control every six months. The changes of debris index (DI), calculus index (CI), probing depth (PD), clinical attachment loss (CAL), bleeding on probing (BOP) and gingival index (GI) before and after

2019 Shanghai kou qiang yi xue = Shanghai journal of stomatology Controlled trial quality: uncertain

5. Health-related quality of life and patient-centred outcomes with olaparib maintenance after chemotherapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT Ov-21): a placebo-controlled, phase 3 randomised tria (Abstract)

Health-related quality of life and patient-centred outcomes with olaparib maintenance after chemotherapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT Ov-21): a placebo-controlled, phase 3 randomised tria In the phase 3 SOLO2 trial (ENGOT Ov-21), maintenance therapy with olaparib tablets significantly prolonged progression-free survival (primary endpoint) compared with placebo in patients with a germline BRCA1 or BRCA2 (BRCA1/2) mutation (...) and platinum-sensitive, relapsed ovarian cancer who had received two or more lines of previous chemotherapy. The most common subjective adverse effects included fatigue, nausea, and vomiting, which were typically low grade and self-limiting. Our a-priori hypothesis was that maintenance olaparib would not negatively affect health-related quality of life (HRQOL) and additionally that the prolongation of progression-free survival with olaparib would be underpinned by additional patient-centred benefits.In

2018 EvidenceUpdates

6. Gym-based exercise was more costly compared with home-based exercise with telephone support when used as maintenance programs for adults with chronic health conditions: cost-effectiveness analysis of a randomised trial Full Text available with Trip Pro

Gym-based exercise was more costly compared with home-based exercise with telephone support when used as maintenance programs for adults with chronic health conditions: cost-effectiveness analysis of a randomised trial What is the comparative cost-effectiveness of a gym-based maintenance exercise program versus a home-based maintenance program with telephone support for adults with chronic health conditions who have previously completed a short-term, supervised group exercise program (...) an additional AUD491,572 from a societal perspective to gain 1 quality-adjusted life year or 1year gained in perfect health compared with the home-based approach. There was considerable uncertainty in this finding, in that there was a 37% probability that the home-based approach was both less costly and more effective than the gym-based approach.The gym-based approach was more costly than the home-based maintenance intervention with telephone support. The uncertainty of these findings suggests

2018 EvidenceUpdates

7. Olaparib for maintenance treatment of BRCA mutation-positive advanced ovarian, fallopian tube or peritoneal cancer after response to first-line platinum-based chemotherapy

Olaparib for maintenance treatment of BRCA mutation-positive advanced ovarian, fallopian tube or peritoneal cancer after response to first-line platinum-based chemotherapy Olaparib for maintenance treatment of Olaparib for maintenance treatment of BR BRCA mutation-positiv CA mutation-positive advanced e advanced o ovarian, fallopian tube or peritoneal varian, fallopian tube or peritoneal cancer after response to first-line cancer after response to first-line platinum-based chemother platinum (...) -based chemotherap apy y T echnology appraisal guidance Published: 28 August 2019 www.nice.org.uk/guidance/ta598 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guidance represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, health professionals are expected to take this guidance

2019 National Institute for Health and Clinical Excellence - Technology Appraisals

8. Rucaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer

equality of opportunity and to reduce health inequalities. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Rucaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer (TA611) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms (...) Rucaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer Rucaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer T echnology appraisal guidance Published: 13 November 2019 www.nice.org.uk/guidance/ta611 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility

2019 National Institute for Health and Clinical Excellence - Technology Appraisals

9. Effectiveness of a novel oral health education technique in maintenance of gingival health and plaque removal efficacy among institutionalized visually impaired children of Bhubaneswar city: A randomized controlled trial. (Abstract)

Effectiveness of a novel oral health education technique in maintenance of gingival health and plaque removal efficacy among institutionalized visually impaired children of Bhubaneswar city: A randomized controlled trial. This study aimed to assess the effectiveness of a novel health education method-Audio Tactile Performance (ATP) technique-in maintenance of gingival health and plaque removal efficacy among institutionalized visually impaired children of Bhubaneswar city.A parallel arm, single (...) blinded randomized controlled trial was conducted among 10- to 15-year-old visually impaired children. Clinical examinations were done by the examiner blinded to group allocations. Oral health education materials (Braille and audio) were given to control group and ATP technique was given to test group. Clinical examinations for plaque and gingival scores were assessed at baseline, 30 days interval, and 90 days interval. The trial was registered with the Clinical Trial Registry of India (CTRI/2017/05

2018 Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry Controlled trial quality: uncertain

10. Predictors of long term weight loss maintenance in patients at high risk of type 2 diabetes participating in a lifestyle intervention program in primary health care: The DE-PLAN study. Full Text available with Trip Pro

Predictors of long term weight loss maintenance in patients at high risk of type 2 diabetes participating in a lifestyle intervention program in primary health care: The DE-PLAN study. Lifestyle interventions in type 2 diabetes (DM2) prevention implementation studies can be effective and lasting. Long-term weight loss maintenance enhances the intervention effect through a significant decrease in diabetes incidence over time. Our objective was to identify factors predicting long-term successful (...) weight reduction maintenance achieved during a DM2 prevention program in patients with high DM2 risk in primary health care. Study participants (n = 263), middle-aged, slightly obese with baseline increased DM2 risk (Finnish Diabetes Risk Score (FINDRISC)>14), but no diabetes were invited to receive 11 lifestyle counselling sessions, guided physical activity sessions and motivational support during 10-months. The study participants had three clinical examinations during the study (baseline, one

2018 PLoS ONE

11. Rucaparib (ovarian, fallopian tube or peritoneal cancer; maintenance treatment) - Benefit assessment according to §35a Social Code Book V

and legally binding. IQWiG Reports – Commission No. A19-23 Rucaparib (ovarian cancer; maintenance treatment) – Benefit assessment according to §35a Social Code Book V 1 Extract of dossier assessment A19-23 Version 1.1 Rucaparib (ovarian cancer; maintenance treatment) 7 August 2019 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher: Institute for Quality and Efficiency in Health Care Topic: Rucaparib (ovarian cancer; maintenance treatment) – Benefit assessment (...) cancer; maintenance treatment) 7 August 2019 Institute for Quality and Efficiency in Health Care (IQWiG) - iii - Table of contents Page List of tables iv List of abbreviations v 2 Benefit assessment 1 2.1 Executive summary of the benefit assessment 1 2.2 Research question 6 2.3 Information retrieval and study pool 6 2.3.1 Studies included 7 2.3.2 Study characteristics 7 2.3.2.1 Description of the study design of the ARIEL3 study 7 2.3.2.2 Implementation of the appropriate comparator therapy

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)

12. Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn's disease. Full Text available with Trip Pro

Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn's disease. Crohn's disease (CD) is a chronic relapsing inflammatory condition and maintenance of remission is a major issue as many patients fail to achieve remission with medical management and require surgical interventions. Purine analogues such as azathioprine (AZA) and 6-mercaptopurine (6-MP) have been used to maintain surgically-induced remission in CD, but the effectiveness, tolerability and safety (...) of these agents remains controversial.To assess the efficacy and safety of purine analogues (AZA and 6-MP) for maintenance of surgically-induced remission in CD.We searched PubMed, MEDLINE, Embase, CENTRAL, and the Cochrane IBD Group Specialized Register from inception to 26 July 2018 (and from inception to 31 July 2019). In addition, we searched reference lists of all included studies and relevant reviews, conference proceedings and trials registers.Randomised controlled trials (RCTs) with a duration

2019 Cochrane Controlled trial quality: predicted high

13. Niraparib for maintenance treatment of relapsed, platinum-sensitive ovarian, fallopian tube and peritoneal cancer

to have due regard to the need to eliminate unlawful discrimination, to advance equality of opportunity and to reduce health inequalities. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Niraparib for maintenance treatment of relapsed, platinum-sensitive ovarian, fallopian tube and peritoneal cancer (TA528) © NICE 2018. All (...) Niraparib for maintenance treatment of relapsed, platinum-sensitive ovarian, fallopian tube and peritoneal cancer Nir Niraparib for maintenance treatment of aparib for maintenance treatment of relapsed, platinum-sensitiv relapsed, platinum-sensitive o e ovarian, varian, fallopian tube and peritoneal cancer fallopian tube and peritoneal cancer T echnology appraisal guidance Published: 4 July 2018 nice.org.uk/guidance/ta528 © NICE 2018. All rights reserved. Subject to Notice of rights (https

2018 National Institute for Health and Clinical Excellence - Technology Appraisals

14. The Role of Chinese Medicine in Health Maintenance and Disease Prevention: Application of Constitution Theory. (Abstract)

The Role of Chinese Medicine in Health Maintenance and Disease Prevention: Application of Constitution Theory. Traditional Chinese medicine (TCM) has guided health maintenance and disease treatment for thousands of years and has been widely used in many countries around the world. TCM regards each individual as unique so all corresponding therapeutic and preventive approaches in TCM are personalized. Personalized medicine, also referred to as precision medicine, is an emerging medical paradigm (...) significantly. This review will introduce and discuss the application of the TCM constitution for health maintenance and disease prevention. In last decade, a number of modern techniques have been employed in the constitution research to evaluate the health status of individuals. The TCM constitution reflects the current status and future trends of human health in four aspects, i.e., individual differences, life processes, psychological condition and adaptability to natural and social environments. This TCM

2019 American Journal of Chinese Medicine

15. Operationalizing the reach, effectiveness, adoption, implementation, maintenance (RE-AIM) framework to evaluate the collective impact of autonomous community programs that promote health and well-being. Full Text available with Trip Pro

Operationalizing the reach, effectiveness, adoption, implementation, maintenance (RE-AIM) framework to evaluate the collective impact of autonomous community programs that promote health and well-being. The RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework is a useful tool for evaluating the impact of programs in community settings. RE-AIM has been applied to evaluate individual programs but seldom used to evaluate the collective impact of community-based (...) , public health programming developed and delivered by multiple autonomous organizations. The purposes of this paper were to (a) demonstrate how RE-AIM can be operationalized and applied to evaluate the collective impact of similar autonomous programs that promote health and well-being and (b) provide preliminary data on the collective impact of Canadian spinal cord injury (SCI) peer mentorship programs on the delivery of peer mentorship services.Criteria from all five RE-AIM dimensions were

2019 BMC Public Health

16. Persuasive System Design Principles and Behavior Change Techniques to Stimulate Motivation and Adherence in Electronic Health Interventions to Support Weight Loss Maintenance: Scoping Review. Full Text available with Trip Pro

Persuasive System Design Principles and Behavior Change Techniques to Stimulate Motivation and Adherence in Electronic Health Interventions to Support Weight Loss Maintenance: Scoping Review. Maintaining weight after weight loss is a major health challenge, and eHealth (electronic health) solutions may be a way to meet this challenge. Application of behavior change techniques (BCTs) and persuasive system design (PSD) principles in eHealth development may contribute to the design of technologies (...) that positively influence behavior and motivation to support the sustainable health behavior change needed.This review aimed to identify BCTs and PSD principles applied in eHealth interventions to support weight loss and weight loss maintenance, as well as techniques and principles applied to stimulate motivation and adherence for long-term weight loss maintenance.A systematic literature search was conducted in PsycINFO, Ovid MEDLINE (including PubMed), EMBASE, Scopus, Web of Science, and AMED, from January 1

2019 Journal of medical Internet research

17. Peer support for the maintenance of physical activity and health in cancer survivors: the PEER trial - a study protocol of a randomised controlled trial. Full Text available with Trip Pro

Peer support for the maintenance of physical activity and health in cancer survivors: the PEER trial - a study protocol of a randomised controlled trial. Despite an overwhelming body of evidence showing the benefits of physical activity (PA) and exercise for cancer survivors, few survivors meet the exercise oncology guidelines. Moreover, initiating, let alone maintaining exercise programs with cancer survivors continues to have limited success. The aim of this trial is to evaluate the influence (...) of peer support on moderate-to-vigorous PA (MVPA) and various markers of health 12 months following a brief supervised exercise intervention in cancer survivors.Men and women previously diagnosed with histologically-confirmed breast, colorectal or prostate cancer (n = 226), who are >1-month post-treatment, will be invited to participate in this trial. Once enrolled, participants will complete 4 weeks (12 sessions) of supervised high intensity interval training (HIIT). On completion of the supervised

2019 BMC Cancer Controlled trial quality: predicted high

18. Maintenance of World Health Organization Risk Drinking Level Reductions and Posttreatment Functioning Following a Large Alcohol Use Disorder Clinical Trial. Full Text available with Trip Pro

Maintenance of World Health Organization Risk Drinking Level Reductions and Posttreatment Functioning Following a Large Alcohol Use Disorder Clinical Trial. Reductions in the World Health Organization (WHO) risk drinking levels have been proposed as an alternative primary outcome for alcohol clinical trials. Yet, little is known about whether reductions in WHO risk drinking levels can be maintained over time. The current study examined whether reductions in WHO risk drinking levels were (...) maintained for up to 1 year following treatment, and whether reductions over time were associated with improvements in functioning.Secondary data analysis of individuals with alcohol dependence (n = 1,226) enrolled in the COMBINE study, a multisite, randomized, placebo-controlled clinical trial. Logistic regression was used to examine the maintenance of end-of-treatment WHO risk level reductions and WHO risk level reductions at the 1-year follow-up. Repeated-measures mixed models were used to examine

2019 Alcoholism, clinical and experimental research Controlled trial quality: uncertain

19. Significant improvement in cardiometabolic health in healthy nonobese individuals during caloric restriction-induced weight loss and weight loss maintenance. Full Text available with Trip Pro

Significant improvement in cardiometabolic health in healthy nonobese individuals during caloric restriction-induced weight loss and weight loss maintenance. Calorie restriction (CR) triggers benefits for healthspan including decreased risk of cardiometabolic disease (CVD). In an ancillary study to CALERIE 2, a 24-mo 25% CR study, we assessed the cardiometabolic effects of CR in 53 healthy, nonobese (BMI: 22-28 kg/m2) men ( n = 17) and women ( n = 36). The aim of this study was to investigate (...) whether CR can reduce risk factors for CVD and insulin resistance in nonobese humans and, moreover, to assess whether improvements are exclusive to a period of weight loss or continue during weight maintenance. According to the energy balance method, the 25% CR intervention ( n = 34) produced 16.5 ± 1.5% (mean ± SE) and 14.8 ± 1.5% CR after 12 and 24 mo (M12, M24), resulting in significant weight loss (M12 -9 ± 0.5 kg, M24 -9 ± 0.5 kg, P < 0.001). Weight was maintained in the group that continued

2019 American journal of physiology. Endocrinology and metabolism Controlled trial quality: uncertain

20. Exploring the Effects of Vitamin D Supplementation on Cognitive Functions and Mental Health Status in Subjects Under Methadone Maintenance Treatment. (Abstract)

Exploring the Effects of Vitamin D Supplementation on Cognitive Functions and Mental Health Status in Subjects Under Methadone Maintenance Treatment. Vitamin D deficiency may be linked to several mental complications including cognitive deficits, depression, and anxiety in patients under methadone maintenance treatment (MMT). This study was designed to explore the effect of vitamin D supplementation on cognitive functions and mental health parameters in subjects under MMT.This randomized (...) , double-blinded, placebo-controlled clinical trial was carried out among 64 patients under MMT. Participants were randomly allocated to receive either 50,000 IU vitamin D supplements (n = 32) or placebo (n = 32) every 2 weeks for 24 weeks. Cognitive functions and mental health parameters were taken at baseline and posttreatment to evaluate relevant variables.After the 24-week intervention, compared with the placebo, serum 25(OH) vitamin D levels significantly increased in participants who received

2019 Journal of addiction medicine Controlled trial quality: predicted high

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