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Healing by Secondary Intention

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162. Programs and services for suicide prevention

Results 10 Discussion of key findings 11 What works to reduce suicide? 12 Gaps in the evidence 12 Policy implications and recommendations 13 Conclusion 15 Background 16 Methods 18 Peer-reviewed literature 18 Procedure and quality assessment 19 Included studies 21 Results 23 Secondary sources (systematic and literature reviews) 24 Overview of secondary sources 24 Universal programs 27 Selective Interventions 30 Targeted interventions 32 Other programs 38 Promising programs 39 Non-clinical promising (...) of strategic alignment 52 Policy implications and recommendations 54 Do no harm 54 The changing nature of suicide 54 Top-down versus bottom-up approaches to suicide prevention 55 Multicomponent programs for priority populations 55 Appendix 1: Screening checklist 59 Appendix 2: Search strings 60 Appendix 3: Summary of secondary sources 63 Appendix 4: Summary of universal programs 76 Appendix 5: Summary of selective programs 82 Appendix 6: Summary of targeted programs 89 Appendix 7: Summary of other programs

2018 Sax Institute Evidence Check

163. Improving social and emotional wellbeing for Aboriginal and Torres Strait Islander people

and community education. The SAM Our Way program targeted Indigenous youth aged 16–24 in five sites in remote and regional Australia. Activities included collaboration with secondary and tertiary education institutions; art, music and sports; bush camps; promotion of culture and identity; building individual, organisational and community capacity; collaborative, community-driven initiatives; education sessions on alcohol and other drugs, mental health and violence; drawing on content from Save-a-Mate

2018 Sax Institute Evidence Check

165. Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Luminal Crohn’s Disease

: TNF; 5-ASA; Guidance; Mucosal Healing Crohn’s disease (CD) is a lifelong illness with substantial mor- bidity and mortality. Studies have shown that up to one-third of patients require hospitalization within the first year after diagnosis and more than half within 5 years. 1 In addition to in- creased risk of mortality from digestive conditions, CD is also associated with a significantly increased risk of all-cause mortal - ity compared with the general population (standardized mor- tality ratio (...) that certain clinical parameters carry an increased risk of progres- sive and disabling disease. In addition, as the association be- tween mucosal healing and improved short-term and long-term outcomes has been increasingly recognized, 4,5 this is becoming an important treatment goal. 6 Evidence suggests that initia- tion of highly effective therapies can lead to symptomatic im- provement and mucosal healing. For this reason the present consensus statements generally recommend that management strategies

2019 Canadian Association of Gastroenterology

166. What is the evidence on the methods, frameworks and indicators used to evaluate health literacy policies, programmes and interventions at the regional, national and organizational levels?

instruments 65iv ABBREVIATIONS AAHLS All Aspects of Health Literacy Scale e-HEALS e-Health Literacy Scale HeLLO Tas! self-assessment checklist for an organization's health literacy HEN Health Evidence Network HLQ Health Literacy Questionnaire HLS-EU European Health Literacy Survey MiMi With Migrants for Migrants – Intercultural Health in Germany (programme) M-POHL Network WHO Action Network on Population and Organizational Health Literacy ÖPGK Austrian Platform for Health Literacy SILS Single Item (...) interaction with health providers and services included adherence to medication, changes in help-seeking intentions and behaviours, changes in access to services, engagement with health providers (including communication) and trust in health providers. Domains relating to organizational health literacy (responsiveness) included changes in the confidence, behaviours and health literacy practices of health practitioners; increased knowledge and awareness of health providers; increased understanding

2019 WHO Health Evidence Network

167. What are the roles of intercultural mediators in health care and what is the evidence on their contributions and effectiveness in improving accessibility and quality of care for refugees and migrants in the WHO European Region?

(26,38,53,54). An example would be translating and adapting health education materials to the cultural characteristics and needs of the target population (32,55,62,97). 2.1.3 Preventing conflict and supporting resolution A common role of intercultural mediators is to anticipate, prevent, negotiate and resolve divergent viewpoints or conflicts between health-care providers and patients (46–48,51,53). These issues may relate to divergent views of health and healing, and highlight the possibility (...) for training programmes vary from completion of lower secondary education to a university degree (for access to a postgraduate

2019 WHO Health Evidence Network

168. WHO consolidated guideline on self-care interventions for health: sexual and reproductive health and rights

or lack of alternatives, it can increase vulnerabilities. TARGET AUDIENCE The primary target audience for this guideline is national and international policy-makers, researchers, programme managers, health workers (including pharmacists), donors and civil society organizations responsible for making decisions or advising on delivery or promotion of self-care interventions. The secondary target audience is product developers. This new guideline is also expected to support persons affected

2019 World Health Organisation Guidelines

170. Management of Acute ST Segment Elevation Myocardial Infarction (STEMI) – (4th Edition)

Management of Acute ST Segment Elevation Myocardial Infarction (STEMI) – (4th Edition) CLINICAL PRACTICE GUIDELINE: MANAGEMENT OF ACUTE ST SEGMENT ELEVATION MYOCARDIAL INFARCTION (STEMI) 4 th EDITION 2019 NATIONAL HEART ASSOCIATION OF MALAYSIA MOH/P/PAK/420.19(GU)-eMANAGEMENT OF ACUTE ST SEGMENT ELEVATION MYOCARDIAL INFARCTION (STEMI) 2019 2 STATEMENT OF INTENT This guideline was developed to be a guide for best clinical practice, based on the best available evidence at the time of development (...) OF ACUTE ST SEGMENT ELEVATION MYOCARDIAL INFARCTION (STEMI) 2019 6 TABLE OF CONTENTS STATEMENT OF INTENT 2 MESSAGE FROM DIRECTOR GENERAL OF HEALTH 3 MEMBERS OF THE EXPERT PANEL 4 EXTERNAL REVIEWERS 5 TABLE OF CONTENTS 6-7 RATIONALE AND PROCESS OF GUIDELINE DEVELOPMENT 8-13 GRADES OF RECOMMENDATION AND LEVELS OF EVIDENCE 14 GLOSSARY 15-18 WHAT’S NEW IN THE CURRENT GUIDELINES 19-22 SUMMARY 23-28 KEY RECOMMENDATIONS 29-32 FLOW CHARTS AND TABLES 33-37 1 INTRODUCTION 38-40 2 DEFINITION AND PATHOGENESIS 41

2019 Ministry of Health, Malaysia

172. Global Vascular Guidelines for patients with chronic limb-threatening ischemia Full Text available with Trip Pro

several leading vascular societies determined to launch the Global Vascular Guidelines (GVG) initiative, CLTI was considered the first priority disease area of focus. The primary goal of this practice guideline on CLTI is to improve the quality of care for all patients with CLTI as well as for those at risk for CLTI. An important secondary goal is to identify key research priorities in need of further basic, translational, clinical, and health services investigation to advance those aims. GVG (...) the term “consider” to denote a conditional recommendation. The level of evidence for each recommendation is considered high quality (A), moderate quality (B), or low quality (C). The guideline also includes good practice recommendations. These ungraded good practice recommendations are supported by a wealth of indirect evidence but no direct evidence, and the benefit of pursuing the recommended actions is considered to outweigh any plausible harm. The intention of these good practice recommendations

2019 Society for Vascular Surgery

173. Darvadstrocel (Alofisel) - non-active / mildly active luminal Crohn’s disease

cytokines. These inflammatory cytokines, particularly interferon-? released by activated lymphocytes, activate eASC. Once activated, eASC impair proliferation of activated lymphocytes and reduce the release of pro-inflammatory cytokines. This immunoregulatory activity reduces inflammation, which may allow the tissues around the fistula tract to heal. 1, 2 The evidence to support the use of darvadstrocel comes from the pivotal, randomised, double- blind, placebo-controlled, phase III study (ADMIRE-CD (...) to study treatment. A combined remission at week 24 was achieved by 50% (53/107) of patients in the darvadstrocel group and 34% (36/105) of patients in the placebo group: difference of 15% (97.5% confidence interval [CI]: 0.2 to 30), p=0.024. There were two key secondary outcomes, clinical remission and clinical response, which were not significantly different between darvadstrocel and placebo at week 24. Clinical remission was defined as closure of all external openings that were draining at baseline

2019 Scottish Medicines Consortium

174. Clinical practice guideline on peri- and postoperative care of arteriovenous fistulas and grafts for haemodialysis in adults Full Text available with Trip Pro

Graded statements within a CPG intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options. Patency See primary unassisted patency or secondary patency. Pre-emptive intervention Intervention aimed at resolving a stenosis or another problem in an AV access that is still adequately providing dialysis; the intention is to avoid the AV access becoming dysfunctional. Primary AV access failure An AV access (...) unassisted patency or secondary patency. Pre-emptive intervention Intervention aimed at resolving a stenosis or another problem in an AV access that is still adequately providing dialysis; the intention is to avoid the AV access becoming dysfunctional. Primary AV access failure An AV access that, despite radiological or surgical intervention, cannot be used successfully for dialysis by a given time point (usually up to three months) following its creation (synonym: dialysis suitability failure). Primary

2019 European Renal Best Practice

175. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder

elements to be abstracted. We dually reviewed citations from the literature search, and then the full text of potentially includable articles for eligibility, resolving any disagreements using consensus. One team member abstracted data from included RCTs into evidence tables, and a second reviewer checked abstracted data for accuracy and completeness. The primary publication for each RCT was abstracted; data and citations from any secondary publications (i.e., companion papers) appear in the same

2019 Effective Health Care Program (AHRQ)

177. Management of Rhinosinusitis in Adolescents and Adults

acknowledgement to MaHTAS is included and the content is not changed, not sold, nor used to promote or endorse any product or service, and not used in an inappropriate or misleading context. ISBN: 978-967-0769-63-9 Available on the following websites: http://www.moh.gov.my http://www.acadmed.org.my http://www.msohns.com Also available as an apps for Android and IOS platform: MyMaHTAS STATEMENT OF INTENT These clinical practice guidelines (CPG) are meant to be guides for clinical practice, based on the best (...) : a) early diagnosis b) treatment c) prevention CLINICAL QUESTIONS Refer to Appendix 2 TARGET POPULATION All adolescents and adults (patients aged >12 years old) with rhinosinusitis (RS) TARGET GROUP/USER This CPG is intended to guide those involved in the management of RS in adolescents and adults either in primary or secondary/tertiary care namely: i. Medical officers and specialists ii. Allied health professionals iii. Trainees and medical students iv. Patients and their advocates v. Professional

2019 Ministry of Health, Malaysia

178. Treatment of Diabetes in Older Adults Full Text available with Trip Pro

heart failure, the following oral hypoglycemic agents should be prescribed with caution to prevent worsening of heart failure: glinides, rosiglitazone, pioglitazone, and dipeptidyl peptidase-4 inhibitors. (Ungraded Good Practice Statement) Management of atherosclerosis in older adults with diabetes 5.9 In patients aged 65 years and older with diabetes and a history of atherosclerotic cardiovascular disease, we recommend low-dosage aspirin (75 to 162 mg/d) for secondary prevention of cardiovascular (...) identified 23 randomized trials. For primary prevention, statins reduced the risk of coronary artery disease and myocardial infarction, but not all-cause or cardiovascular mortality or stroke. These effects were imprecise in patients with diabetes, but there was no significant interaction between diabetes status and the intervention effect. For secondary prevention, statins reduced all-cause mortality, cardiovascular mortality, coronary artery disease, myocardial infarction, and revascularization

2019 The Endocrine Society

179. Bioresorbable Stents in cardiovascular indications (coronary artery disease)

) • Cohort study 1mm in >2 contiguous leads, or (presumably new) left bundle branch block, or true posterior MI with ST depression of >1 mm in >2 contiguous anterior leads • Primary PCI within 24 hours of symptom onset • 1 or more acute infarct artery target vessel with one or more coronary artery stenoses in a native coronary artery (Maximumø 2.50-3.80 mm) Primary endpoint • Optical frequency domain imaging-derived healing score at 6 months Maximumfollow-up Angiographic: 6 months Clinical: 36 months

2019 EUnetHTA

180. The economic evaluation of early intervention with Anti-Tumor Necrosis Factor-alpha treatments in pediatric Crohn's disease

6 1.3 Anti-TNF-a Interventions and How They Might Work 7 1.4 Clinical Efficacy of Anti-TNF-a Treatments in Pediatric Crohn’s Disease 8 1.4.1 Studies and Reviews of the Clinical Efficacy of Anti-TNF-a Treatments 8 1.5 Economic Evaluations and Health Technology Assessments of Anti-TNF-a Treatments in Crohn’s Disease 13 1.6 Treatment Pathway in Crohn’s Disease 18 1.7 Theoretical Framework 19 1.8 The Problem 23 1.9 Primary Objective 23 1.10 Secondary Objective 24 1.11 Research Design 25 Methods 27 (...) at week 26 compared to the standard care (“step-up”) group (35.9%) (Geert D'Haens et al., 2008), and, more importantly, greater likelihood of sustained mucosal healing (Baert et al., 2010). Another similar trial in adult CD patients showed similar remission rates among early intervention and step-up comparator groups at 24 months, but a lower adverse event rate in the early anti-TNF-a intervention group (Khanna et al., 2015). A review of predominantly adult studies has concluded

2019 SickKids Reports

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