How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,873 results for

Healing by Secondary Intention


Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

141. Esomeprazole

peptic ulcers are a common disorder. However, whether or not aspirin should be continued during treatment (...) for aspirin-related ulcers remains unclear. To compare esomeprazole alone with esomeprazole plus aspirin in the treatment of aspirin-related peptic ulcers and to investigate the independent factors associated with the failure of ulcer healing. From January 2008 to July 2011, patients with aspirin-related peptic ulcers were randomized to receive esomeprazole (40 mg per day) alone (...) 20 mg (standard therapy) or 40 mg (double-dose therapy), each given twice daily. At intention-to-treat analysis, H. pylori infection was cured in 73.9 2016 11. Esomeprazole for the Treatment of GERD in Infants Ages 1-11 Months. 26422097 2015 10 01 2016 06 29 2015 10 01 1536-4801 60 Suppl 1 2015 Jul Journal of pediatric gastroenterology and nutrition J. Pediatr. Gastroenterol. Nutr. Esomeprazole for the Treatment of GERD in Infants Ages 1-11 Months. S9-15 10.1097/MPG.0b013e3182496b35

2018 Trip Latest and Greatest

142. Programs and services for suicide prevention

Results 10 Discussion of key findings 11 What works to reduce suicide? 12 Gaps in the evidence 12 Policy implications and recommendations 13 Conclusion 15 Background 16 Methods 18 Peer-reviewed literature 18 Procedure and quality assessment 19 Included studies 21 Results 23 Secondary sources (systematic and literature reviews) 24 Overview of secondary sources 24 Universal programs 27 Selective Interventions 30 Targeted interventions 32 Other programs 38 Promising programs 39 Non-clinical promising (...) of strategic alignment 52 Policy implications and recommendations 54 Do no harm 54 The changing nature of suicide 54 Top-down versus bottom-up approaches to suicide prevention 55 Multicomponent programs for priority populations 55 Appendix 1: Screening checklist 59 Appendix 2: Search strings 60 Appendix 3: Summary of secondary sources 63 Appendix 4: Summary of universal programs 76 Appendix 5: Summary of selective programs 82 Appendix 6: Summary of targeted programs 89 Appendix 7: Summary of other programs

2018 Sax Institute Evidence Check

144. Improving social and emotional wellbeing for Aboriginal and Torres Strait Islander people

and community education. The SAM Our Way program targeted Indigenous youth aged 16–24 in five sites in remote and regional Australia. Activities included collaboration with secondary and tertiary education institutions; art, music and sports; bush camps; promotion of culture and identity; building individual, organisational and community capacity; collaborative, community-driven initiatives; education sessions on alcohol and other drugs, mental health and violence; drawing on content from Save-a-Mate

2018 Sax Institute Evidence Check

145. BSG consensus guidelines on the management of inflammatory bowel disease in adults

in ‘histological healing’[41] • Treat to target: The goal being more than symptomatic remission with the intention of reducing risk of future relapse or complications (e.g. ileal strictures or colon cancer) resulting from uncontrolled but asymptomatic inflammation.[41, 42] Future studies are required to define targets, the practicality of achieving targets, and to examine the balance of benefit vs. risk and cost • Therapeutic Drug Monitoring (TDM): Measurement of drug (+/- anti-drug antibody) levels to assess (...) -recommendations for pharmacological, non- pharmacological and surgical interventions, as well as optimal service delivery in the management of both ulcerative colitis and Crohn’s disease. Comprehensive, up-to-date guidance is provided regarding indications for, initiation and monitoring of immunosuppressive therapies, nutrition interventions, pre-, peri- and post-operative management, as well as structure and function of the multidisciplinary team, and integration between primary and secondary care. Twenty

2019 British Society of Gastroenterology

146. Clinical practice guideline on peri- and postoperative care of arteriovenous fistulas and grafts for haemodialysis in adults (Full text)

Graded statements within a CPG intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options. Patency See primary unassisted patency or secondary patency. Pre-emptive intervention Intervention aimed at resolving a stenosis or another problem in an AV access that is still adequately providing dialysis; the intention is to avoid the AV access becoming dysfunctional. Primary AV access failure An AV access (...) unassisted patency or secondary patency. Pre-emptive intervention Intervention aimed at resolving a stenosis or another problem in an AV access that is still adequately providing dialysis; the intention is to avoid the AV access becoming dysfunctional. Primary AV access failure An AV access that, despite radiological or surgical intervention, cannot be used successfully for dialysis by a given time point (usually up to three months) following its creation (synonym: dialysis suitability failure). Primary

2019 European Renal Best Practice

147. WHO consolidated guideline on self-care interventions for health: sexual and reproductive health and rights

or lack of alternatives, it can increase vulnerabilities. TARGET AUDIENCE The primary target audience for this guideline is national and international policy-makers, researchers, programme managers, health workers (including pharmacists), donors and civil society organizations responsible for making decisions or advising on delivery or promotion of self-care interventions. The secondary target audience is product developers. This new guideline is also expected to support persons affected

2019 World Health Organisation Guidelines

148. Global Vascular Guidelines for patients with chronic limb-threatening ischemia (Full text)

several leading vascular societies determined to launch the Global Vascular Guidelines (GVG) initiative, CLTI was considered the first priority disease area of focus. The primary goal of this practice guideline on CLTI is to improve the quality of care for all patients with CLTI as well as for those at risk for CLTI. An important secondary goal is to identify key research priorities in need of further basic, translational, clinical, and health services investigation to advance those aims. GVG (...) the term “consider” to denote a conditional recommendation. The level of evidence for each recommendation is considered high quality (A), moderate quality (B), or low quality (C). The guideline also includes good practice recommendations. These ungraded good practice recommendations are supported by a wealth of indirect evidence but no direct evidence, and the benefit of pursuing the recommended actions is considered to outweigh any plausible harm. The intention of these good practice recommendations

2019 Society for Vascular Surgery

149. Darvadstrocel (Alofisel) - non-active / mildly active luminal Crohn’s disease

cytokines. These inflammatory cytokines, particularly interferon-? released by activated lymphocytes, activate eASC. Once activated, eASC impair proliferation of activated lymphocytes and reduce the release of pro-inflammatory cytokines. This immunoregulatory activity reduces inflammation, which may allow the tissues around the fistula tract to heal. 1, 2 The evidence to support the use of darvadstrocel comes from the pivotal, randomised, double- blind, placebo-controlled, phase III study (ADMIRE-CD (...) to study treatment. A combined remission at week 24 was achieved by 50% (53/107) of patients in the darvadstrocel group and 34% (36/105) of patients in the placebo group: difference of 15% (97.5% confidence interval [CI]: 0.2 to 30), p=0.024. There were two key secondary outcomes, clinical remission and clinical response, which were not significantly different between darvadstrocel and placebo at week 24. Clinical remission was defined as closure of all external openings that were draining at baseline

2019 Scottish Medicines Consortium

150. Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children: A Joint Position Paper From the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for

transplantation was defined as ‘‘a transfer of biologic material containing a minimally manipulated community of microorganisms from a human donor to a human recipient (including autologous use) with the intent of affecting the microbiota of the recipient’’ (1). In the case of FMT, fecal material is used. Throughout this manuscript, the term FMT is used. Other Received April 4, 2018; accepted October 3, 2018. From the Department of Pediatric Gastroenterology, Digestive Diseases, Hepatology, and Nutrition (...) microbiome may affect its ability to tolerate or resist a transplanted microbiome and enable mucosal healing. Furthermore, both safety and efficacy take on a new meaning when applied to children with 20 to 30 additional life-years compared to adults. In a letter to the FDA, the Joint Society Consensus Recommendation (JSCR) (102) states that ‘‘children could also potentially serve as donors as long as both parental consent and child assent are obtained.’’ Further research on age-matched donors

2019 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

152. The economic evaluation of early intervention with Anti-Tumor Necrosis Factor-alpha treatments in pediatric Crohn's disease

6 1.3 Anti-TNF-a Interventions and How They Might Work 7 1.4 Clinical Efficacy of Anti-TNF-a Treatments in Pediatric Crohn’s Disease 8 1.4.1 Studies and Reviews of the Clinical Efficacy of Anti-TNF-a Treatments 8 1.5 Economic Evaluations and Health Technology Assessments of Anti-TNF-a Treatments in Crohn’s Disease 13 1.6 Treatment Pathway in Crohn’s Disease 18 1.7 Theoretical Framework 19 1.8 The Problem 23 1.9 Primary Objective 23 1.10 Secondary Objective 24 1.11 Research Design 25 Methods 27 (...) at week 26 compared to the standard care (“step-up”) group (35.9%) (Geert D'Haens et al., 2008), and, more importantly, greater likelihood of sustained mucosal healing (Baert et al., 2010). Another similar trial in adult CD patients showed similar remission rates among early intervention and step-up comparator groups at 24 months, but a lower adverse event rate in the early anti-TNF-a intervention group (Khanna et al., 2015). A review of predominantly adult studies has concluded

2019 SickKids Reports

153. Bioresorbable Stents in cardiovascular indications (coronary artery disease)

) • Cohort study 1mm in >2 contiguous leads, or (presumably new) left bundle branch block, or true posterior MI with ST depression of >1 mm in >2 contiguous anterior leads • Primary PCI within 24 hours of symptom onset • 1 or more acute infarct artery target vessel with one or more coronary artery stenoses in a native coronary artery (Maximumø 2.50-3.80 mm) Primary endpoint • Optical frequency domain imaging-derived healing score at 6 months Maximumfollow-up Angiographic: 6 months Clinical: 36 months

2019 EUnetHTA

154. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder

elements to be abstracted. We dually reviewed citations from the literature search, and then the full text of potentially includable articles for eligibility, resolving any disagreements using consensus. One team member abstracted data from included RCTs into evidence tables, and a second reviewer checked abstracted data for accuracy and completeness. The primary publication for each RCT was abstracted; data and citations from any secondary publications (i.e., companion papers) appear in the same

2019 Effective Health Care Program (AHRQ)

156. Treatment of Diabetes in Older Adults

heart failure, the following oral hypoglycemic agents should be prescribed with caution to prevent worsening of heart failure: glinides, rosiglitazone, pioglitazone, and dipeptidyl peptidase-4 inhibitors. (Ungraded Good Practice Statement) Management of atherosclerosis in older adults with diabetes 5.9 In patients aged 65 years and older with diabetes and a history of atherosclerotic cardiovascular disease, we recommend low-dosage aspirin (75 to 162 mg/d) for secondary prevention of cardiovascular (...) identified 23 randomized trials. For primary prevention, statins reduced the risk of coronary artery disease and myocardial infarction, but not all-cause or cardiovascular mortality or stroke. These effects were imprecise in patients with diabetes, but there was no significant interaction between diabetes status and the intervention effect. For secondary prevention, statins reduced all-cause mortality, cardiovascular mortality, coronary artery disease, myocardial infarction, and revascularization

2019 The Endocrine Society

158. Management of Rhinosinusitis in Adolescents and Adults

acknowledgement to MaHTAS is included and the content is not changed, not sold, nor used to promote or endorse any product or service, and not used in an inappropriate or misleading context. ISBN: 978-967-0769-63-9 Available on the following websites: Also available as an apps for Android and IOS platform: MyMaHTAS STATEMENT OF INTENT These clinical practice guidelines (CPG) are meant to be guides for clinical practice, based on the best (...) : a) early diagnosis b) treatment c) prevention CLINICAL QUESTIONS Refer to Appendix 2 TARGET POPULATION All adolescents and adults (patients aged >12 years old) with rhinosinusitis (RS) TARGET GROUP/USER This CPG is intended to guide those involved in the management of RS in adolescents and adults either in primary or secondary/tertiary care namely: i. Medical officers and specialists ii. Allied health professionals iii. Trainees and medical students iv. Patients and their advocates v. Professional

2019 Ministry of Health, Malaysia

159. British Association of Dermatologists and U.K. Curaneous Lymphoma Group (CLG) guidelines for the management of primary cutaneous lymphomas

of primary cutaneous CD30 + lymphoproliferative disorders and is de?ned by a history of recurrent, self-healing papules and nodules, and characteristic pathology. CBCL presents with nodules, plaques and tumours with a characteristic pathology and immunophenotype, and site local- ization can be an important distinguishing feature. A de?nitive diagnosis can only be made on a representative biopsy, prefer- ably an excision or elliptical biopsy. Borrelia burgdorferi infection has been reported in association (...) required for other CTCL variants and for high- grade PCLBCL leg type. Bone marrow biopsy and aspirate is considered optional for low-grade PCMZL but should be con- sidered for PCFCL, as systemic follicle centre lymphoma with secondary cutaneous involvement may occur. 19,20 Serum lac- tate dehydrogenase has prognostic signi?cance and should be checked at diagnosis. 21 Existing staging systems for nodal lymphomas are not appli- cable for primary cutaneous lymphomas. The original TNM (primary tumour

2019 British Association of Dermatologists

160. Syphilis in pregnancy

Primary · Lesions begin as a raised papule that ulcerates (chancre) and may 16,26,4 : o Be painless or painful (approximately half reported as painful) 33 o Be solitary or multiple (approximately one third reported as multiple) 33 o Typically occur at the site of inoculation (e.g. vagina, penis, anus, rectum, lips, in or on the mouth) o Discharge clear serum—may also be purulent, destructive o Spontaneously heals within three to six weeks without treatment Secondary · Follows untreated primary stage (...) primary, secondary and early latent stages). Consider the possibility of infectious syphilis if duration is unknown and there are no symptoms and/or no evidence of adequate treatment. Syphilis requiring treatment in pregnancy In this guideline, syphilis requiring treatment in pregnancy is used to mean infectious syphilis that is treated during the current pregnancy OR syphilis of unknown duration or late latent syphilis that is untreated, has been inadequately treated, or where there is no history

2019 Queensland Health

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>