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Healing by Secondary Intention

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21. Excision and Reconstruction of the Natal Cleft With a Parasacral Perforator Flap Versus Open Excision With Secondary Healing, in the Management of Sacrococcygeal Pilonidal Disease.

sacrococcygeal pilonidal disease is a common acquired condition associated with hirsutism that predominantly affects young male patients. Morbidity from this disease results in pain, embarrassment and loss of normal activities, causing absenteeism from work and school. Various surgical procedures have been described for the treatment of both primary and recurrent pilonidal disease counting: open excision and healing by secondary intention, marsupialization, excision and primary closure (midline or off (...) cluster versus 7.5% in the excision with healing by secondary intention cluster. The time for complete wound healing was also significantly amended . The reconstruction of the natal cleft with a Karydakis or Limberg flap seemed to be superior in terms of recurrence compared to open excision. But those flaps led to a significant and discernable scar. The parasacral perforator flap has been described by Garrido et al. in 2002. It appears to be a good alternative, offering all the benefits

2017 Clinical Trials

22. Pressurised irrigation versus swabbing method in cleansing wounds healed by secondary intention: A randomised controlled trial with cost-effectiveness analysis. (Abstract)

Pressurised irrigation versus swabbing method in cleansing wounds healed by secondary intention: A randomised controlled trial with cost-effectiveness analysis. Wound cleansing should create an optimal healing environment by removing excess debris, exudates, foreign and necrotic material which are commonly present in the wounds that heal by secondary intention. At present, there is no research evidence for whether pressurised irrigation has better wound healing outcomes compared (...) with conventional swabbing practice in cleansing wound.This study investigated the differences between pressurised irrigation and swabbing method in cleansing wounds that healed by secondary intention in relation to wound healing outcomes and cost-effectiveness.Multicentre, prospective, randomised controlled trial.The study took place in four General Outpatient Clinics in Hong Kong.Two hundred and fifty six patients with wounds healing by secondary intention were randomly assigned by having a staff independent

2014 International journal of nursing studies Controlled trial quality: predicted high

23. Healing Septal Perforations by Secondary Intention Using Acellular Dermis as a Bioscaffold. (Abstract)

Healing Septal Perforations by Secondary Intention Using Acellular Dermis as a Bioscaffold. Several techniques are described in the literature for nasal septal perforation repair. Most of these involve interposition grafts in conjunction with local pedicled mucosal flaps. The following article describes our experience using acellular dermis as a bioscaffold to support the regrowth of nasal septal mucosa by secondary intention.Retrospective chart review of all patients who underwent repair (...) technique and were able to be completely closed with a single additional procedure.Acellular dermis offers an alternative to most currently described complex flaps. The method can be used in patients with defects less than 2 cm, but initial data suggest caution when using in those with wound healing impediments. This technique is also an excellent choice for patients with multiple small septal perforations.© The Author(s) 2014.

2014 Rhinology and Laryngology

24. The Role of the Undermining during Circular Excision of Secondary Intention Healing. (Abstract)

The Role of the Undermining during Circular Excision of Secondary Intention Healing. Circular excision by secondary intention healing is useful for small skin defects. The study compared the effect of the neighboring undermining on wound healing. Patients undergoing circular excision (diameters less than 20 mm) were divided into four groups in sequence by the range of neighboring subcutaneous undermining. Key outcome measures were complication rate, healing time, mature scar width, and quality (...) , but there was no difference between Groups 3 and 4. The undermining of the surrounding tissue is useful to promote secondary intention healing of small skin defects and to improve the cosmetic results of the final scar. The study compared the effect of neighboring undermining on wound secondary healing of circular excision. Key outcome measures were complication rate, healing time, mature scar width, and quality. Statistical differences between different undermining types were used.

2014 The American surgeon Controlled trial quality: uncertain

25. A prospective case series of secondary intention healing for surgical wounds on the dorsum of the hand. (Abstract)

A prospective case series of secondary intention healing for surgical wounds on the dorsum of the hand. The dorsum of the hand is a common site for squamous cell carcinoma, and excision with appropriate margins often results in surgical defects that cannot be repaired by primary side-to-side closure.To assess healing time, complications and resulting scars when surgical wounds on the dorsum of the hand were allowed to heal by secondary intention.This was a prospective study of 28 surgical (...) defects on the dorsum of the hand, which were allowed to heal by secondary intention. Patients were followed up on days 2, 7 and 14, and then every 2 weeks until the wounds healed. Wound dressings were changed 2-3 times per week. Patients' tolerance of this treatment and their degree of satisfaction with the final results was determined.The defect diameters ranged from 15 to 46 mm (median 24 mm). The time to heal was determined in 24 patients, and ranged from 22 to 63 days (median 44 days). There were

2013 Clinical & Experimental Dermatology

26. Secondary intention healing in skin surgery: our own experience and expanded indications in hidradenitis suppurativa, rhinophyma and non-melanoma skin cancers. (Abstract)

Secondary intention healing in skin surgery: our own experience and expanded indications in hidradenitis suppurativa, rhinophyma and non-melanoma skin cancers. There are many situations in integument surgery in which secondary intention healing (SIH) may bring results comparable or even superior to those obtained with primary intention healing.To present our own methods of employing SIH in surgical treatment of different skin lesions. Moreover, to delineate the extended indications for SIH (...) defects after the excision of non-melanoma skin cancers and hidradenitis suppurativa lesions. Depending on localization, the mean extent of the post-operative wounds prepared for SIH ranged from 0.8to 85.7 cm(2). The healing lasted 2-12 weeks. The most important factor was the size of the wound (r = 0.59; P < 0.001). The assessment at 12 months revealed that cosmetic/functional outcomes were evaluated as 'good' or 'excellent' in 89/83% and 72/70% cases, according to patients and physicians

2013 Journal of the European Academy of Dermatology and Venereology

27. Comparison of negative pressure wound therapy and secondary intention healing after excision of acral lentiginous melanoma on the foot. (Abstract)

Comparison of negative pressure wound therapy and secondary intention healing after excision of acral lentiginous melanoma on the foot. Melanoma in dark-skinned individuals often develops in an acral lentiginous fashion on the foot and wide excision usually results in a substantial defect. Various repair methods, including free flap, full-thickness skin graft and secondary intention healing (SIH), are used to repair these defects. Recently, use of negative pressure wound treatment (NPWT) has (...) been shown to accelerate wound healing in different types of wound.To compare the functional and cosmetic results of NPWT and SIH in patients who underwent wide excision of melanomas on the foot.The wound defects of 22 patients after wide excision of melanoma on the foot were treated using SIH (n = 13) or NPWT (n = 9).There was no significant difference in time to complete wound healing between the two groups. However, evaluation using the Vancouver Burn Scar Assessment Scale at the time

2013 British Journal of Dermatology

28. Perineorrhaphy Compared With Pelvic Floor Muscle Therapy in Women With Late Consequences of a Poorly Healed Second-Degree Perineal Tear: A Randomized Controlled Trial Full Text available with Trip Pro

at least 6 months postpartum. Methods: We performed a single center, open-label, randomized controlled trial. After informed consent, patients with a poorly healed second-degree perineal tear at minimum 6 months postpartum were randomized to either surgery or physical therapy. The primary outcome was treatment success, as defined by Patient Global Impression of Improvement, at 6 months. Secondary outcomes included the Pelvic Floor Distress Inventory, the Pelvic Floor Impact Questionnaire, the Pelvic (...) to physical therapy regarding all secondary endpoints. Conclusion: Surgical treatment is effective and superior to pelvic floor muscle training in relieving symptoms related to a poorly healed second-degree perineal tear in women presenting at least 6 months postpartum. Clinical trial registration: ClinicalTrials.gov, . Similar articles L Leeman et al. Birth 43 (4), 293-302. Dec 2016. PMID 27797099. Women having second-degree lacerations are not at increased risk for pelvic floor dysfunction other than

2020 EvidenceUpdates

29. Negative pressure wound therapy for treating surgical wounds healing by secondary intention [Cochrane Protocol]

Negative pressure wound therapy for treating surgical wounds healing by secondary intention [Cochrane Protocol] Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence (...) of administration, frequency of administration, route of administration, vehicle. ">Data to be extracted: intervention of interest Example: Serum creatinine; continuous; umol/L (may be recalculated from mg/dL). ">Data to be extracted: primary outcome(s) Example: Blood urea nitrogen; continuous; mmol/L (may be recalculated from mg/dL); Renal histological damage as assessed by Jablonski scale; continuous; Jablonski score. ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication

2015 PROSPERO

30. Antibiotics and antiseptics for surgical wounds healing by secondary intention [Cochrane Protocol]

Antibiotics and antiseptics for surgical wounds healing by secondary intention [Cochrane Protocol] Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web (...) of administration, route of administration, vehicle. ">Data to be extracted: intervention of interest Example: Serum creatinine; continuous; umol/L (may be recalculated from mg/dL). ">Data to be extracted: primary outcome(s) Example: Blood urea nitrogen; continuous; mmol/L (may be recalculated from mg/dL); Renal histological damage as assessed by Jablonski scale; continuous; Jablonski score. ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data

2015 PROSPERO

31. Healing by Secondary Intention

Healing by Secondary Intention Healing by Secondary Intention Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Healing by Secondary (...) Intention Healing by Secondary Intention Aka: Healing by Secondary Intention , Secondary Healing From Related Chapters II. Indications Prolonged delay between and treatment See Minor soft tissue amputations without bone loss Less than 1 cm square in size No significant volar pulp loss If unsure Temporize with management below Arrange follow-up and possible graft in 1-2 days III. Management Cleansing Debridement Healing by Secondary Intention Dressing Changes Twice daily for 2 days after injury

2015 FP Notebook

32. Doubleblinded RCT of the Omnilux on Lower Extremity Surgical Wounds Left to Heal by Second Intention

Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Surgical defect on the lower extremity left to heal by secondary intention. If women of child bearing potential, contraceptive measures should be used Maximum size of wound is 5cm x5cm; there is no minimum size for the wound. Exclusion Criteria: History of porphyria photosensitive eruptions, diabetes mellitus, history of venous insufficiency, known history of peripheral arterial disease (ABI <0.8) Use of any ointments or creams containing (...) Identifier: Other Study ID Numbers: 20120475 First Posted: March 9, 2015 Last Update Posted: November 9, 2017 Last Verified: November 2017 Keywords provided by Keyvan Nouri, University of Miami: wound secondary intention healing lower extremity Additional relevant MeSH terms: Layout table for MeSH terms Wounds and Injuries Surgical Wound

2015 Clinical Trials

33. Primary & Secondary Prevention of CVD

Primary & Secondary Prevention of CVD 2016 1 STATEMENT OF INTENT This guideline was developed to be a guide for best clinical practice in the prevention of cardiovascular disease, based on the best available evidence at the time of development. Specific attempts were made to use local data and publications to ensure local relevance. Adherence to this guideline does not necessarily lead to the best clinical outcome in individual patient care as this depends on other clinical factors like co (...) in mortality rates in overweight diabetic individuals following an intentional weight loss of 20-29 lb (9-13 kg). 96 A randomized trial however, focusing on weight loss using intensive lifestyle intervention, did not reduce the rate of CV events in overweight or obese adults with type 2 diabetes. 97 Bariatric surgery in obese individuals has been associated with improved survival in the long term. 98-100 Primary & Secondary Prevention of Cardiovascular Disease 201738 5.2.5 Hypertension Epidemiological

2017 Ministry of Health, Malaysia

34. Topical Nitroglycerin for Peripheral Circulation and Wound Healing in the Elderly

Topical Nitroglycerin for Peripheral Circulation and Wound Healing in the Elderly Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should (...) identified. PREPARED BY: Canadian Agency for Drugs and Technologies in Health Tel: 1-866-898-8439 www.cadth.ca Topical Nitroglycerin for Peripheral Circulation and Wound Healing in the Elderly 4 APPENDIX – FURTHER INFORMATION: Systematic Reviews and Meta-analyses – Unclear Population Age 1. Herrick A. Raynaud's phenomenon (secondary). Clin Evid (Online) [Internet]. 2008;2008 [cited 2015 Feb 17]. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907943 PubMed: PM19445801 Randomized Controlled

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

35. Efficacy of hypnosis on pain, wound-healing, anxiety, and stress in children with acute burn injuries: a randomized controlled trial Full Text available with Trip Pro

presenting for their first dressing change were randomly assigned to a Hypnosis Group who received hypnosis plus standard care or a Standard Care Group who received standard pharmacological and nonpharmacological intervention. Repeated measures of pain intensity, anxiety, stress, and wound-healing were taken at dressing changes until ≥95% wound re-epithelialization. Data for 62 children were analyzed on an intent-to-treat basis using Generalized Estimating Equations (n = 35 Standard Care Group; n = 27 (...) Hypnosis Group). An effect on the primary outcomes of pain and wound healing was not supported {self-reported pain intensity largest Mean Difference [MD] = -0.85 (95% confidence interval [CI]: -1.91 to 0.22), P = 0.12; MD for re-epithelialization = -0.46 [95% CI: -4.27 to 3.35], P = 0.81}. Some support was found for an effect on the secondary outcomes of preprocedural anxiety (MD = -0.80 [95% CI: -1.50 to -0.10], P = 0.03 before the second dressing change) and heart rate as a measure of stress (MD

2018 EvidenceUpdates

36. Comparison of Full-Thickness Skin Grafts Versus Second-Intention Healing for Mohs Defects of the Helix. (Abstract)

scale (VAS). Patient questionnaires and retrospective chart analysis were used to assess secondary outcomes.The average second-intention VAS score was 82.1 (standard deviation [SD] = 7.6), and the average FTSG VAS score was 75.2 (SD = 16.7) (difference of 6.9, 95% confidence interval: -1.3 to 15.1, p = .061). A subsequent noninferiority test indicated that cosmetic outcome of second-intention healing was at least as good as that of FTSG in the authors' study (p < .001). Retrospective chart analysis (...) Comparison of Full-Thickness Skin Grafts Versus Second-Intention Healing for Mohs Defects of the Helix. Two repair options for Mohs defects of the helix include full-thickness skin grafting and second-intention healing. Limited long-term data exist comparing these 2 repair options.To compare outcomes of full-thickness skin grafts (FTSG) versus second-intention wound healing for Mohs defects on the helix.In this study, 29 second-intention and 18 FTSG repairs were evaluated using a visual analog

2014 Dermatologic Surgery

37. Purse-String Suture vs Second Intention Healing: Results of a Randomized, Blind Clinical Trial. Full Text available with Trip Pro

for the secondary intention group, a nonsignificant difference (P = .41). Similarly, there were no significant differences for any of the following secondary outcome measures: mean total patient POSAS score (P = .96), mean scar-to-defect area (P = .61), and mean pain level at week 1 (P = .19). Statistical trends toward significance were seen in the mean healing time in favor of purse-string suture (P = .10) and scar relief, which favored second intention healing (P = .07).The purse-string suture results (...) in similar cosmetic outcomes, scar sizes, and pain levels compared with second intention healing for circular or oval wounds on the trunk and extremities. A larger study might better define the potential differences in our secondary outcome measures of healing time and scar relief.clinicaltrials.gov Identifier: NCT02062866.

2014 JAMA dermatology (Chicago, Ill.) Controlled trial quality: predicted high

38. Consciousness Field Project: Intention Host Device-mediated Distant Intentionality

for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Dr. Gabriele Hilberg, PhD, MFT, Merraki Institute: Intention Distant Healing Wellness Distant Intentionality Distant Healing Intention (...) Consciousness Field Project: Intention Host Device-mediated Distant Intentionality Consciousness Field Project: Intention Host Device-mediated Distant Intentionality - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2017 Clinical Trials

39. Intentional partial odontectomy—a long-term follow-up study Full Text available with Trip Pro

Intentional partial odontectomy—a long-term follow-up study The surgical extraction of the third molar is the most frequently encountered procedure in oral and maxillofacial surgery and is related with a variety of complications. This study examined the efficacy of intentional partial odontectomy (IPO) in the third molars which have no periapical lesions and are located near important anatomical structures such as inferior alveolar nerve.Seven patients (four males, three females, 39.1 ± 11.6 (...)  years), who received IPO to reduce the risk of inferior alveolar nerve injury (IANI), were followed long-term. The treated teeth were horizontally impacted third molars in the mandibular left (n = 5) or mandibular right (n = 4) areas and were all ankylosed with the surrounding alveolar bone. During the IPO, the bone around the crown was removed to expose the crown, and then the tooth was resected at cement-enamel junction (CEJ). Any secondary trauma to the healthy root was minimized and remained

2017 Maxillofacial Plastic and Reconstructive Surgery

40. Secondary suturing compared to non-suturing for broken down perineal wounds following childbirth. Full Text available with Trip Pro

scientific evidence and no clear guidelines to inform best practice. For most women the wound will be managed expectantly whereas, others may be offered secondary suturing.To evaluate the therapeutic effectiveness of secondary suturing of dehisced perineal wounds compared to non-suturing (healing by secondary intention, expectancy).We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (31 July 2013) and reference lists of retrieved studies.Randomised controlled trials of secondary (...) Secondary suturing compared to non-suturing for broken down perineal wounds following childbirth. Each year approximately 350,000 women in the United Kingdom and millions more worldwide, experience perineal suturing following childbirth. The postpartum management of perineal trauma is a core component of routine maternity care. However, for those women whose perineal wound dehisces (breaks down), the management varies depending on individual practitioners preferences as there is limited

2013 Cochrane

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