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Headache-Related Neuroimaging

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141. Validation of the Ottawa Subarachnoid Hemorrhage Rule in patients with acute headache (Full text)

Validation of the Ottawa Subarachnoid Hemorrhage Rule in patients with acute headache We previously derived the Ottawa Subarachnoid Hemorrhage Rule to identify subarachnoid hemorrhage (SAH) in patients with acute headache. Our objective was to validate the rule in a new cohort of consecutive patients who visited an emergency department.We conducted a multicentre prospective cohort study at 6 university-affiliated tertiary-care hospital emergency departments in Canada from January 2010 (...) to January 2014. We included alert, neurologically intact adult patients with a headache peaking within 1 hour of onset. Treating physicians in the emergency department explicitly scored the rule before investigations were started. We defined subarachnoid hemorrhage as detection of any of the following: subarachnoid blood visible upon computed tomography of the head (from the final report by the local radiologist); xanthochromia in the cerebrospinal fluid (by visual inspection); or the presence

2017 EvidenceUpdates PubMed

142. Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Headache: Approved by the ACEP Board of Directors June 26, 2019 Clinical Policy Endorsed by the Emergency Nurses Associat (PubMed)

a systematic review of the literature to derive evidence-based recommendations to answer the following clinical questions: (1) In the adult emergency department patient presenting with acute headache, are there risk-stratification strategies that reliably identify the need for emergent neuroimaging? (2) In the adult emergency department patient treated for acute primary headache, are nonopioids preferred to opioid medications? (3) In the adult emergency department patient presenting with acute headache (...) Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Headache: Approved by the ACEP Board of Directors June 26, 2019 Clinical Policy Endorsed by the Emergency Nurses Associat This clinical policy from the American College of Emergency Physicians addressed key issues in the evaluation and management of adult patients presenting to the emergency department with acute headache. A writing subcommittee conducted

2019 Annals of Emergency Medicine

143. Does This Patient with Minor Head Trauma Need Neuroimaging?

Does This Patient with Minor Head Trauma Need Neuroimaging? SystematicReviewSnapshot TAKE-HOME MESSAGE The Canadian CT Head Rule may be useful in reducing unnecessary neuroimaging in patients with minor head injuries. METHODS DATA SOURCES The authors reviewed potentially relevant studies identi?ed through electronic searches of MEDLINE, EMBASE, CINAHL, and CEN- TRAL up to April 2009, supple- mented with an update from MEDLINE to March 2010. Refer- ence lists in key publications were used (...) were resolved by consen- sus or by a third reviewer. Be- cause of signi?cant heterogeneity, a meta-analysis could not be per- formed; instead, the authors re- ported the range of diagnostic accuracy across cohorts. Does This Patient With Minor Head Trauma Need Neuroimaging? EBEM Commentators Dylan D. Cooper, MD Rawle A. Seupaul, MD Department of Emergency Medicine Indiana University School of Medicine Indianapolis, IN Results Table 1. Range of point estimates for sensitivity and speci?city

2012 Annals of Emergency Medicine Systematic Review Snapshots

144. Headache - assessment

[ ]. Severe hypertension (often described as greater than 180mm Hg systolic or 110 mm Hg diastolic), [ ] is a rare cause of secondary headache [ ] Neurological examination Physical examination is important to rule out serious causes of headache (such as tumour) [ ]. A study looking at 1876 consecutive patients with non-acute headache in a neurology clinic found that only 0.9% (95% CI 0.5-1.4) without neurological signs had significant pathology on neuroimaging [ ]. Investigations The diagnosis of primary (...) system cancer in young people (birth to 24 years of age) with newly abnormal cerebellar or other central neurological function. Progressive headache A headaches that worsens with time may be the result of a progressive intracranial lesion such as tumour, subdural hematoma, or hydrocephalus. As neurological examination may not always be abnormal, the Institute for Clinical Systems Improvement recommend neuroimaging to assess for serious underlying causes in such cases [ ]. New onset headache over

2017 NICE Clinical Knowledge Summaries

145. Headache - cluster

. If clinical features are consistent with cluster headache refer to/discuss with a neurologist or GP with a special interest in headache all: People presenting with a first bout of cluster headache — confirmation of diagnosis by a specialist is required and may involve neuroimaging. Preventative treatment (such as verapamil) may be considered. People with confirmed cluster headache who have developed new symptoms or signs suggestive of a serious underlying secondary cause. Pregnant or breastfeeding women (...) ) [ ] recommends: Consideration of neuroimaging and specialist assessment in people presenting with a first bout of cluster headache. Referral of all pregnant women with cluster headache to neurology. The British Association for the Study of Headache (BASH) recommend management of cluster headache by specialists who see the disorder frequently [ ]. Acute treatment of confirmed cluster headache Evidence based treatments for relief of individual cluster attacks include subcutaneous or nasal triptans and oxygen

2017 NICE Clinical Knowledge Summaries

146. Guideline for primary care management of headache in adults

. Medications for tension-type headache View this table: Table 4. Medications for cluster headache: Consider early specialist referral. Box 1. General practice points for managing primary headache in adults The following are general practice points for the management of primary headache in adults: Rule out secondary headache when diagnosing a primary headache disorder Neuroimaging is not indicated in patients with recurrent headache with the clinical features of migraine, normal neurologic examination (...) findings, and no red flags Neuroimaging, sinus or cervical spine x-ray scans, and electroencephalograms are not recommended for the routine assessment of patients with headache: history and physical and neurologic examination findings are usually sufficient to make a diagnosis of migraine or tension-type headache Migraine is by far the most common headache type in patients seeking help for headache from physicians Migraine is historically underdiagnosed and undertreated; many patients with migraine

2015 Institute of Health Economics

147. Neuroimaging and Neuromonitoring in Critically Ill Children With Sepsis

Observational Model: Cohort Time Perspective: Prospective Official Title: Neuroimaging and Neuromonitoring in Critically Ill Children With Sepsis Actual Study Start Date : February 1, 2017 Estimated Primary Completion Date : December 31, 2020 Estimated Study Completion Date : December 31, 2020 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Group/Cohort Intervention/treatment Sepsis Children with severe sepsis or septic shock Diagnostic Test: MR imaging (...) Neuroimaging and Neuromonitoring in Critically Ill Children With Sepsis Neuroimaging and Neuromonitoring in Critically Ill Children With Sepsis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Neuroimaging

2017 Clinical Trials

148. Neuroimaging Studies of Practice and Smoking

Neuroimaging Studies of Practice and Smoking Neuroimaging Studies of Practice and Smoking - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Neuroimaging Studies of Practice and Smoking (COPE) The safety (...) ) Primary Purpose: Prevention Official Title: Smoking Cessation and Brain Activation: How Practice Changes the Brain Actual Study Start Date : December 2016 Estimated Primary Completion Date : June 30, 2019 Estimated Study Completion Date : June 30, 2019 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Practice Participants will be asked to delay time to smoking first cigarette of the day for up to two weeks

2017 Clinical Trials

149. Synchronous rTMS and Computer-integrated Speech Training Applied in Aphasic Patients and the Neuroimaging Study

Synchronous rTMS and Computer-integrated Speech Training Applied in Aphasic Patients and the Neuroimaging Study Synchronous rTMS and Computer-integrated Speech Training Applied in Aphasic Patients and the Neuroimaging Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Synchronous rTMS and Computer-integrated Speech Training Applied in Aphasic Patients and the Neuroimaging Study The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03059225 Recruitment Status : Unknown Verified January 2017 by Taipei

2017 Clinical Trials

150. ADHD, Smoking Withdrawal and Inhibitory Control: Results of a Neuroimaging Study with Methylphenidate Challenge. (PubMed)

ADHD, Smoking Withdrawal and Inhibitory Control: Results of a Neuroimaging Study with Methylphenidate Challenge. Smoking withdrawal negatively impacts inhibitory control, and these effects are greater for smokers with preexisting attention problems, such as attention deficit/hyperactivity disorder (ADHD). The current study preliminarily evaluated changes in inhibitory control-related behavior and brain activation during smoking withdrawal among smokers with ADHD. Moreover, we investigated (...) analysis of task-related BOLD signal revealed a significant group-by-abstinence interaction in occipital/parietal cortex during sustained inhibition, with greater abstinence-induced decreases in activation observed among ADHD smokers compared with non-ADHD smokers. Changes in behavioral performance during abstinence were associated with changes in activation in regions of occipital and parietal cortex and bilateral insula during sustained inhibition in both groups. MPH administration improved

2017 Neuropsychopharmacology

151. Machine learning applied to neuroimaging for diagnosis of adult classic Chiari malformation: role of the basion as a key morphometric indicator. (PubMed)

Machine learning applied to neuroimaging for diagnosis of adult classic Chiari malformation: role of the basion as a key morphometric indicator. OBJECTIVE The current diagnostic criterion for Chiari malformation Type I (CM-I), based on tonsillar herniation (TH), includes a diversity of patients with amygdalar descent that may be caused by a variety of factors. In contrast, patients presenting with an overcrowded posterior cranial fossa, a key characteristic of the disease, may remain (...) model based on 3 parameters, all related to the basion location, to discern classic CM-I with 90% accuracy and suggest considering the anterior alterations in the evaluation of surgical procedures and outcomes.

2017 Journal of Neurosurgery

152. Neuroimaging Biomarker for Seizures

Neuroimaging [ Time Frame: Baseline and week 13 ] Brain MRI scans Secondary Outcome Measures : Beck Depression Inventory-II (BDI-II) [ Time Frame: Baseline, Weeks 1,2,3,4,5,6,7,8,9,10,11,12, 8 months post baseline, 12 months post baseline ] The BDI-II assesses depression severity from "0" (no Depression-related symptom) to "3" (severe) on each question. The highest possible score is "51", relating to the worst outcome. Beck Anxiety Inventory (BAI) [ Time Frame: Baseline, Weeks 6 and 10, 8 months post (...) Neuroimaging Biomarker for Seizures Neuroimaging Biomarker for Seizures - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Neuroimaging Biomarker for Seizures (NIBMSZS) The safety and scientific validity

2017 Clinical Trials

153. Abnormal brain activation during threatening face processing in schizophrenia: A meta-analysis of functional neuroimaging studies. (PubMed)

Abnormal brain activation during threatening face processing in schizophrenia: A meta-analysis of functional neuroimaging studies. Impairment of face perception in schizophrenia is a core aspect of social cognitive dysfunction. This impairment is particularly marked in threatening face processing. Identifying reliable neural correlates of the impairment of threatening face processing is crucial for targeting more effective treatments. However, neuroimaging studies have not yet obtained robust (...) conclusions. Through comprehensive literature search, twenty-one whole brain datasets were included in this meta-analysis. Using seed-based d-Mapping, in this voxel-based meta-analysis, we aimed to: 1) establish the most consistent brain dysfunctions related to threating face processing in schizophrenia; 2) address task-type heterogeneity in this impairment; 3) explore the effect of potential demographic or clinical moderator variables on this impairment. Main meta-analysis indicated that patients

2017 Schizophrenia Research

154. Correlations between clinical characteristics and neuroimaging in Chinese patients with subtypes of frontotemporal lobe degeneration. (Full text)

Correlations between clinical characteristics and neuroimaging in Chinese patients with subtypes of frontotemporal lobe degeneration. The aim of the study was to obtain an overview of the clinical and neuroimaging features of Chinese patients with subtypes of frontotemporal lobe degeneration (FTLD).We evaluated the demographic features, clinical presentation, and lobe atrophy depicted by magnetic resonance imaging (MRI) in 133 patients with FTLD. Two positron emission tomography (PET) scans (...) significantly correlated with the degree of overall atrophy. The severity of abnormal behavior was correlated with right anterior and right posterior temporal atrophy scores. The overall atrophy scores and atrophy score in the left temporal region were related to cognitive outcomes and Activities of Daily Living scores. Most of the bvFTD patients presented symmetric/asymmetric hypometabolism in the bilateral temporal cortex, frontal cortex, anterior cingulate cortex, insula, and caudate nucleus. All

2017 Medicine PubMed

155. Structural Neuroimaging and Neuropsychologic Signatures of Vertically Acquired HIV. (PubMed)

performances nor laboratory markers corresponded to brain volumes in the HIV-infected children.Outcomes of the present study suggest abnormal brain maturation among HIV-infected pediatric survivors. Longitudinal studies of brain integrity and related resilience factors are needed to determine the impact of neuroimaging abnormalities on psychosocial function in pediatric HIV. (...) Structural Neuroimaging and Neuropsychologic Signatures of Vertically Acquired HIV. Children with vertically acquired HIV exhibit persistent cognitive impairments, yet the corresponding neuroimaging signature of vertical infection remains unclear.Fifty healthy control children and 51 vertically infected children were included in the study. The HIV-infected group consisted of survivors who had not received antiretroviral therapy at birth. The HIV-infected group averaged 11.4 (2.5) years of age

2017 Pediatric Infectious Dsease Journal

156. Tracking Brain Development and Dimensional Psychiatric Symptoms in Children: A Longitudinal Population-Based Neuroimaging Study. (PubMed)

Tracking Brain Development and Dimensional Psychiatric Symptoms in Children: A Longitudinal Population-Based Neuroimaging Study. Psychiatric symptomatology during childhood predicts persistent mental illness later in life. While neuroimaging methodologies are routinely applied cross-sectionally to the study of child and adolescent psychopathology, the nature of the relationship between childhood symptoms and the underlying neurodevelopmental processes remains unclear. The authors used (...) microstructural measures over time.Higher ratings for externalizing and internalizing symptoms at baseline predicted smaller increases in both subcortical gray matter volume and global fractional anisotropy over time. The reverse relationship did not hold; thus, baseline measures of gray matter and white matter were not significantly related to changes in symptom ratings over time.Children presenting with behavioral problems at an early age show differential subcortical and white matter development. Most

2017 American Journal of Psychiatry

157. Science News » Neuroimaging technique may help predict autism among high-risk infants

of 93 percent. “Although the findings are early-stage, the study suggests that in the future, neuroimaging may be a useful tool to diagnose autism or help health care providers evaluate a child’s risk of developing the disorder,” said Joshua Gordon, M.D., Ph.D., NIMH Director. Overall, the team found 974 functional connections in the brains of 6-month-olds that were associated with autism-related behaviors. The authors propose that a single neuroimaging scan may accurately predict autism among high (...) Science News » Neuroimaging technique may help predict autism among high-risk infants NIMH » Neuroimaging Technique May Help Predict Autism among High-Risk Infants Mental Health Information Outreach Research Funding News & Events About Us Transforming the understanding and treatment of mental illnesses. Search the NIMH Website: > > Recent News March 26, 2019 March 19, 2019 March 13, 2019 March 11, 2019 February 20, 2019 News by Year News by Topic Disorders Populations Prevention Research Other

2017 NIMH blog

158. Defining the Neural Substrate of the Adult Outcome of Childhood ADHD: A Multimodal Neuroimaging Study of Response Inhibition. (Full text)

Defining the Neural Substrate of the Adult Outcome of Childhood ADHD: A Multimodal Neuroimaging Study of Response Inhibition. Understanding the neural processes tied to the adult outcome of childhood attention deficit hyperactivity disorder (ADHD) could guide novel interventions to improve its clinical course. It has been argued that normalization of prefrontal cortical activity drives remission from ADHD, while anomalies in subcortical processes are "fixed," present even in remission. Using (...) multimodal neuroimaging of inhibitory processes, the authors tested these hypotheses in adults followed since childhood, contrasting remitted against persistent ADHD.Adult participants (persistent ADHD, N=35; remit-ted ADHD, N=47; never affected, N=99) were scanned with functional MRI (fMRI) (N=85), magnetoencephalography (N=33), or both (N=63) during a response inhibition task.In fMRI analyses, during inhibition, right caudate anomalies reflected a childhood ADHD history and were present even among

2017 American Journal of Psychiatry PubMed

159. Effects of computerized cognitive training on neuroimaging outcomes in older adults: a systematic review. (Full text)

Effects of computerized cognitive training on neuroimaging outcomes in older adults: a systematic review. Worldwide, the population is aging and the number of individuals diagnosed with dementia is rising rapidly. Currently, there are no effective pharmaceutical cures. Hence, identifying lifestyle approaches that may prevent, delay, or treat cognitive impairment and dementia in older adults is becoming increasingly important. Computerized Cognitive Training (CCT) is a promising strategy (...) to combat cognitive decline. Yet, the underlying mechanisms of the effect of CCT on cognition remain poorly understood. Hence, the primary objective of this systematic review was to examine peer-reviewed literature ascertaining the effect of CCT on both structural and functional neuroimaging measures among older adults to gain insight into the underlying mechanisms by which CCT may benefit cognitive function.In accordance with PRISMA guidelines, we used the following databases: MEDLINE, EMBASE

2017 BMC geriatrics PubMed

160. The influence of emotional interference on cognitive control: A meta-analysis of neuroimaging studies using the emotional Stroop task. (Full text)

The influence of emotional interference on cognitive control: A meta-analysis of neuroimaging studies using the emotional Stroop task. The neural correlates underlying the influence of emotional interference on cognitive control remain a topic of discussion. Here, we assessed 16 neuroimaging studies that used an emotional Stroop task and that reported a significant interaction effect between emotion (stimulus type) and cognitive conflict. There were a total of 330 participants, equaling 132 (...) foci for an activation likelihood estimation (ALE) analysis. Results revealed consistent brain activation patterns related to emotionally-salient stimuli (as compared to emotionally-neutral trials) during cognitive conflict trials [incongruent trials (with task-irrelevant information interfering), versus congruent/baseline trials (less disturbance from task-irrelevant information)], that span the lateral prefrontal cortex (dorsolateral prefrontal cortex and inferior frontal gyrus), the medial

2017 Scientific reports PubMed

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