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Headache-Related Neuroimaging

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41. Sex- and Age-Related Differences in the Clinical and Neuroimaging Characteristics of Patients With Spontaneous Intracranial Hypotension: A Records Review. (PubMed)

Sex- and Age-Related Differences in the Clinical and Neuroimaging Characteristics of Patients With Spontaneous Intracranial Hypotension: A Records Review. The significance of sex- and age-related differences in the clinical course of spontaneous intracranial hypotension (SIH) was investigated.We retrospectively studied 40 consecutive patients (female:male = 28:12, median age 41.5 years) treated under clinical diagnoses of SIH satisfying the International Classification of Headache Disorders 3rd (...) edition criteria, including 37 patients (92.5%) with diffuse pachymeningeal enhancement. The patients were divided into two groups by age and sex, and the clinical and neuroimaging findings in each group were investigated.Acute onset (female:male = 82.1%:50.0%, P = .042), severe headache (75.0%:41.7%, P = .045) occurred with higher frequency in females than in males, and SDH occurred with lower frequency in females than in males (28.6%:75.0%, P = .006). Duration until the consultation (2:14 days, P

2016 Headache

42. Non‐parametric combination and related permutation tests for neuroimaging (PubMed)

Non‐parametric combination and related permutation tests for neuroimaging In this work, we show how permutation methods can be applied to combination analyses such as those that include multiple imaging modalities, multiple data acquisitions of the same modality, or simply multiple hypotheses on the same data. Using the well-known definition of union-intersection tests and closed testing procedures, we use synchronized permutations to correct for such multiplicity of tests, allowing

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2016 Human brain mapping

43. Memory-related white matter tract integrity in amyotrophic lateral sclerosis: an advanced neuroimaging and neuropsychological study. (PubMed)

Memory-related white matter tract integrity in amyotrophic lateral sclerosis: an advanced neuroimaging and neuropsychological study. We aimed to investigate structural changes in vivo in memory-related white matter tracts (i.e., perforant pathway zone [PPZ]; uncinate fasciculus [UF]; fornix) using diffusion tensor tractography and evaluate possible associations with memory performance in nondemented patients with amyotrophic lateral sclerosis (ALS). Forty-two ALS patients and 25 healthy (...) -Immediate Recall; and (3) left PPZ FA and left UF axial diffusivity contributed to Babcock Story Recall Test-Immediate and Delayed Recall. Advanced neuroimaging techniques verified in this study previously reported neuropathological findings regarding PPZ degeneration in ALS. We also detected a unique contribution of microstructural changes in hippocampal and frontotemporal white matter tracts on patients' memory profile.Copyright © 2016 Elsevier Inc. All rights reserved.

2016 Neurobiology of Aging

44. Emotional Processing in Obsessive-Compulsive Disorder: A Systematic Review and Meta-analysis of 25 Functional Neuroimaging Studies.

Emotional Processing in Obsessive-Compulsive Disorder: A Systematic Review and Meta-analysis of 25 Functional Neuroimaging Studies. Patients with obsessive-compulsive disorder (OCD) experience aversive emotions in response to obsessions, motivating avoidance and compulsive behaviors. However, there is considerable ambiguity regarding the brain circuitry involved in emotional processing in OCD, especially whether activation is altered in the amygdala.We conducted a systematic literature review (...) and performed a meta-analysis-seed-based d mapping-of 25 whole-brain neuroimaging studies (including 571 patients and 564 healthy control subjects) using functional magnetic resonance imaging or positron emission tomography, comparing brain activation of patients with OCD and healthy control subjects during presentation of emotionally valenced versus neutral stimuli. Meta-regressions were employed to investigate possible moderators.Patients with OCD, compared with healthy control subjects, showed increased

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2018 Biological psychiatry. Cognitive neuroscience and neuroimaging

45. The Effects of Air Pollution on the Brain: a Review of Studies Interfacing Environmental Epidemiology and Neuroimaging (PubMed)

The Effects of Air Pollution on the Brain: a Review of Studies Interfacing Environmental Epidemiology and Neuroimaging An emerging body of evidence has raised concern regarding the potentially harmful effects of inhaled pollutants on the central nervous system during the last decade. In the general population, traffic-related air pollution (TRAP) exposure has been associated with adverse effects on cognitive, behavior, and psychomotor development in children, and with cognitive decline (...) . The detected brain damages could be involved in cognition changes. The effect of TRAP on cognition appears to be biologically plausible. Interfacing environmental epidemiology and neuroimaging is an emerging field with room for improvement. Future studies, together with inputs from experimental findings, should provide more relevant and detailed knowledge about the nature of the relationship between TRAP exposure and cognitive, behavior, and psychomotor disorders observed in the general population.

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2018 Current environmental health reports

46. Functional magnetic neuroimaging data on age-related differences in task switching accuracy and reverse brain-behavior relationships (PubMed)

Functional magnetic neuroimaging data on age-related differences in task switching accuracy and reverse brain-behavior relationships The data presented in this article is related to the research article entitled "Age-related Differences in BOLD Modulation to Cognitive Control Costs in a Multitasking Paradigm: Global Switch, Local Switch, and Compatibility-Switch Costs" (Nashiro et al., 2018) [1]. This article describes age-related differences in accuracies for various cognitive costs incurred (...) during task switching across three different age-cohorts: younger (18-35 years), younger-old (50-64 years) and older-old (65-80 years). The cognitive costs evaluated were global switch costs (GSC), local switch costs (LSC) and compatibility switch costs (CSC). Whole brain analyses were conducted to determine the brain regions sensitive to these cognitive costs, irrespective of age. Furthermore, age-related differences in brain-behavior relationships were evaluated by correlating activations from

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2018 Data in brief

47. The Appropriate Use of Neuroimaging in the Diagnostic Work-Up of Dementia

The Appropriate Use of Neuroimaging in the Diagnostic Work-Up of Dementia The Appropriate Use of Neuroimaging in the Diagnostic Work-Up of Dementia: OHTAC Recommendation. February 2014; pp. 1–12 The Appropriate Use of Neuroimaging in the Diagnostic Work-Up of Dementia: OHTAC Recommendation Ontario Health Technology Advisory Committee February 2014 The Appropriate Use of Neuroimaging in the Diagnostic Work-Up of Dementia: OHTAC Recommendation. February 2014; pp. 1–12 2 Suggested Citation (...) This report should be cited as follows: Ontario Health Technology Advisory Committee (OHTAC). The appropriate use of neuroimaging in the diagnostic work-up of dementia: OHTAC recommendation [Internet]. Toronto: Queen's Printer for Ontario; 2014 February. 12 p. Available from: http://www.hqontario.ca/evidence/publications-and-ohtac-recommendations/ontario-health- technology-assessment-series/imaging-for-dementia. Permission Requests All inquiries regarding permission to reproduce any content in Health

2014 Health Quality Ontario

48. The appropriate use of neuroimaging in the diagnostic work-up of dementia: an economic literature review and cost-effectiveness analysis

by Health Quality Ontario, Canada. Bibliographic details Bermingham SL. The appropriate use of neuroimaging in the diagnostic work-up of dementia: an economic literature review and cost-effectiveness analysis. Toronto, ON, Canada: Health Quality Ontario. Ontario Health Technology Assessment Series; 14(2). 2014 PubMedID Original Paper URL Other publications of related interest Neumann PJ, Hermann R, Kuntz K, Araki SS, Duff SB, Leon J, et al. Cost-effectiveness of donepezil in the treatment of mild (...) The appropriate use of neuroimaging in the diagnostic work-up of dementia: an economic literature review and cost-effectiveness analysis The appropriate use of neuroimaging in the diagnostic work-up of dementia: an economic literature review and cost-effectiveness analysis The appropriate use of neuroimaging in the diagnostic work-up of dementia: an economic literature review and cost-effectiveness analysis Bermingham SL Record Status This is an economic evaluation that meets the criteria

2014 NHS Economic Evaluation Database.

49. Functional and structural neuroimaging studies of delayed reward discounting in addiction: A systematic review. (PubMed)

Functional and structural neuroimaging studies of delayed reward discounting in addiction: A systematic review. Given the robust behavioral association between delayed reward discounting (DRD) and addictive behavior, there is an expanding literature investigating the neural correlates of this relationship. The objective of this systematic review was to characterize and critically appraise the existing literature examining the neural correlates of DRD in individuals exhibiting addictive behavior (...) the executive control, salience, and default mode networks in individuals exhibiting addictive behavior. Structural MRI studies reported highly heterogeneous findings and no consistent conclusions could be drawn. As a whole, this review suggests consistent differences in neural activation and connectivity relating to DRD in individuals with addictive disorders. It also reveals heterogeneity of methods and findings in this line of inquiry. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

2019 Psychological Bulletin

50. Predementia Brain Changes in Progranulin Mutation: A Systematic Review of Neuroimaging Evidence. (PubMed)

Predementia Brain Changes in Progranulin Mutation: A Systematic Review of Neuroimaging Evidence. Mutations in the progranulin (GRN) gene are a major cause of familial frontotemporal dementia. They result in a loss of progranulin levels and in GRN-related brain degenerative changes that unfold over years if not decades. The aim of our review was to summarize the evidence on emerging functional and structural brain abnormalities in carriers of GRN mutations.We performed a systematic search

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2019 Dementia and Geriatric Cognitive Disorders

51. Clinical Characteristics and Neuroimaging Findings in Internal Jugular Venous Outflow Disturbance. (PubMed)

Clinical Characteristics and Neuroimaging Findings in Internal Jugular Venous Outflow Disturbance. Recently, internal jugular vein stenosis (IJVS) is gaining increasing attention from clinical researchers due to a series of confounding symptoms that impair the quality of life in affected individuals but cannot be explained by other well-established causes. In this study, we aimed to elucidate the clinical features, neuroimaging characteristics and pathogenesis of IJVS, and explore (...) evaluated by single-photon emission computed tomography (SPECT). Of the 43 patients (46.0 ± 16.0 years old; 30 female), 14 (32.6%) had bilateral and 29 had unilateral IJVS. The common clinical symptoms at admission were tinnitus (60.5%), tinnitus cerebri (67.6%), headache (48.8%), dizziness (32.6%), visual disorders (39.5%), hearing impairment (39.5%), neck discomfort (39.5%), sleep disturbance (60.5%), anxiety or depression (37.5%) and subjective memory decline (30.2%). The presence of bilateral

2019 Thrombosis and haemostasis

52. Neuroimaging auditory verbal hallucinations in schizophrenia patient and healthy populations. (PubMed)

Neuroimaging auditory verbal hallucinations in schizophrenia patient and healthy populations. Auditory verbal hallucinations (AVH) are a cardinal feature of schizophrenia, but they can also appear in otherwise healthy individuals. Imaging studies implicate language networks in the generation of AVH; however, it remains unclear if alterations reflect biologic substrates of AVH, irrespective of diagnostic status, age, or illness-related factors. We applied multimodal imaging to identify AVH

2019 Psychological Medicine

53. Structural brain alterations following adult non-CNS cancers: a systematic review of the neuroimaging literature. (PubMed)

Structural brain alterations following adult non-CNS cancers: a systematic review of the neuroimaging literature. Cancer and cancer treatments may impact the brain through several pathways leading to cognitive impairment. Neuroimaging evidence has begun to elucidate the neurobiological underpinnings of cancer-related cognitive impairment. The aim of this paper was to systematically review available literature on structural brain alterations following adult non-central nervous system (CNS (...) ) cancers and associated treatments.This review followed PRISMA guidelines and was registered in PROSPERO (ID#107387). Comprehensive searches were conducted in June 2018 using PubMed and Web of Science. Inclusion criteria were English peer-reviewed journal articles of formal, controlled studies that examined structural neuroimaging outcomes in adult non-CNS cancer patients and survivors. Selected articles were assessed for quality and risk of bias using the National Institutes of Health Quality

2019 Acta Oncologica

54. Do chronic pain and comorbidities affect brain function in sickle cell patients? A systematic review of neuroimaging and treatment approaches. (PubMed)

on brain function. Titles were screened using predefined criteria, including SCD, and abstracts and full texts were reviewed by 2 independent reviewers. A total of 1,167 SCD articles were identified and 86 full articles were included covering 3 sections: chronic pain (4 studies), psychosocial comorbidities (11 studies), and pharmacological and nonpharmacological treatments (71 studies). Neuroimaging evidence demonstrates aberrant neural processing related to chronic pain and psychosocial comorbidities (...) in SCD beyond ischemic stroke and cerebral hemorrhage. Although neuroimaging studies show an important role for psychological factors, pain management is nearly exclusively based on opioids. Behavior therapy appears useful to improve psychological symptoms as well as chronic pain and quality of life. Further investigation is required with larger cohorts, matched-controls, and examination of treatment-related neural mechanisms.

2019 Pain

55. Recent Insights in Migraine With Aura: A Narrative Review of Advanced Neuroimaging. (PubMed)

Recent Insights in Migraine With Aura: A Narrative Review of Advanced Neuroimaging. Migraine is a complex neurological disorder characterized by severe headaches associated with a plethora of sensory hypersensitivity and neurovegetative symptoms. In about one-third of the cases, a set of fully reversible focal neurological symptoms, the aura, accompanies the headache. In the last decades, advanced neuroimaging investigations allowed identification of structural, microstructural, and functional (...) phenomena, they have failed in identifying underlying pathophysiological mechanisms in their entirety. Nevertheless, functional and structural neuroimaging findings concerning the extrastriate visual cortex are characterized by a high level of reproducibility, so much so that they could be applied, in a not so far future, as diagnostic, prognostic, or therapeutic biomarkers for MwA.© 2019 American Headache Society.

2019 Headache

56. Olfactory Dysfunction Mediates Adiposity in Cognitive Impairment of Type 2 Diabetes: Insights From Clinical and Functional Neuroimaging Studies. (PubMed)

Olfactory Dysfunction Mediates Adiposity in Cognitive Impairment of Type 2 Diabetes: Insights From Clinical and Functional Neuroimaging Studies. Large numbers of people with type 2 diabetes are obese. However, changes in cognition and related brain function in obese people with diabetes have not been characterized. Here, we investigated cognition, olfactory function, and odor-induced brain alterations in these patients and therapeutic effects of glucagon-like peptide 1 receptor agonists (GLP (...) -1Ras) on their psychological behavior and olfactory networks.Cognitive, olfactory, and odor-induced brain activation assessments were administered to 35 obese and 35 nonobese people with type 2 diabetes and 35 control subjects matched for age, sex, and education. Among them, 20 obese individuals with diabetes with inadequate glycemic control and metformin monotherapy received GLP-1Ra treatment for 3 months and were reassessed for metabolic, cognitive, olfactory, and neuroimaging changes.Obese

2019 Diabetes Care

57. Comparison of Taiji and aerobic exercise for functional constipation: study protocol for a randomised controlled neuroimaging trial. (PubMed)

Comparison of Taiji and aerobic exercise for functional constipation: study protocol for a randomised controlled neuroimaging trial. Taiji has been proven to be effective for regulating both the physical and mental state compared with simple aerobic exercise. However, whether the improvement of Taiji for constipation is related to regulate imbalanced brain-gut axis and emotional disorder for functional constipation (FC) remains uncertain. The results of the study will demonstrate (...) the differences in regulation brain-gut balance between Taiji and simply aerobic exercise for patients with FC and provide a potential therapy for clinical treatment of FC, and a new approach for the research of mind-body exercise.In this randomised controlled neuroimaging trial, 80 patients with FC will be allocated into two groups: Taiji group and aerobic exercise group. The two groups will receive 10 weeks of Taiji exercise or aerobic exercise, respectively. The stool diary, Cleveland Constipation Score

2019 BMJ open

58. Variability of physicians' thresholds for neuroimaging in children with recurrent headache. (PubMed)

Variability of physicians' thresholds for neuroimaging in children with recurrent headache. We sought to determine the extent to which physicians agree about the appropriate decision threshold for recommending magnetic resonance imaging in a clinical practice guideline for children with recurrent headache.We surveyed attending physicians in Canada practicing in community pediatrics, child neurology, pediatric radiology, and pediatric neurosurgery. For children in each of six risk categories (...) they ordered neuroimaging less often than peers were less likely to recommend neuroimaging for the 1% risk group (all p < 0.05).There is no consensus among pediatric specialists regarding the appropriate decision threshold for neuroimaging in a clinical practice guideline for children with recurrent headache. Because of the impact that individual threshold preferences may have on guidelines, these findings support the need for careful composition of guideline committees and consideration of the role

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2014 BMC Pediatrics

59. Role of advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion: a systematic review. (PubMed)

Role of advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion: a systematic review. To conduct a systematic review of published literature on advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion (SRC).Computerised searches of Medline, PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, Scopus and Cochrane Library from 1 January 2000 to 31 December 2016 were (...) done. There were 3222 articles identified.In addition to medical subject heading terms, a study was included if (1) published in English, (2) represented original research, (3) involved human research, (4) pertained to SRC and (5) involved data from neuroimaging, fluid biomarkers or genetic testing collected within 6 months of injury. Ninety-eight studies qualified for review (76 neuroimaging, 16 biomarkers and 6 genetic testing).Separate reviews were conducted for neuroimaging, biomarkers

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2017 British Journal of Sports Medicine

60. The appropriate use of neuroimaging in the diagnostic work-up of dementia: An evidence-based analysis

made for the HTA database. Citation Health Quality Ontario. The appropriate use of neuroimaging in the diagnostic work-up of dementia: an evidence-based analysis. Toronto: Health Quality Ontario (HQO). Ontario Health Technology Assessment Series (OHTAS) 14(1). 2014 Authors' conclusions With the exception of dementia related to vascular disease, prevalence of potentially treatable dementias is low (< 10%), and improvement after treatment of the underlying condition is less than 1% (GRADE: Very low (...) The appropriate use of neuroimaging in the diagnostic work-up of dementia: An evidence-based analysis The appropriate use of neuroimaging in the diagnostic work-up of dementia: an evidence-based analysis The appropriate use of neuroimaging in the diagnostic work-up of dementia: an evidence-based analysis Health Quality Ontario Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been

2014 Health Technology Assessment (HTA) Database.

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