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Headache in Pregnancy

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81. Cervical ripening before first trimester surgical evacuation for non-viable pregnancy. (PubMed)

are required to determine whether the benefits of this treatment outweigh the risks. Further research should be powered to assess the rate of cervical and uterine injury between interventions. Future research should also guide clinicians in deciding whether the benefits of reduced manual cervical dilatation outweigh the risks of adverse effects associated with these agents (nausea, vomiting, headache, fever, diarrhoea and pain). Women's satisfaction and outcomes of future pregnancies should also (...) Cervical ripening before first trimester surgical evacuation for non-viable pregnancy. Medications or mechanical dilators are often used to soften and dilate the cervix prior to surgical evacuation of the uterus for non-viable pregnancy, or miscarriage. The majority of miscarriages occur in the first trimester. The aim of cervical ripening is to reduce the possibility of injury to the uterus and cervix and improve the surgical ease of the procedure. Cervical ripening agents can have adverse

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2015 Cochrane

82. PRAC recommends new measures to avoid valproate exposure in pregnancy

PRAC recommends new measures to avoid valproate exposure in pregnancy PRAC recommends new measures to avoid valproate exposure in pregnancy | European Medicines Agency Search Search Menu PRAC recommends new measures to avoid valproate exposure in pregnancy Press release 09/02/2018 New restrictions on use; pregnancy prevention programme to be put in place The European Medicines Agency's experts in medicines safety, the ( ) are recommending new measures to avoid exposure of babies to valproate (...) medicines in the womb. Babies exposed are at risk of malformations and developmental problems. What are the main measures recommended by the ? Where licensed for migraine or bipolar disorder : In pregnancy - valproate must not be used. In female patients from the time they become able to have children – valproate must not be used unless the conditions of a new pregnancy prevention programme ( ) are met. For epilepsy: In pregnancy - valproate must not be used. However it is recognised that for some women

2018 European Medicines Agency - EPARs

83. Stroke in Pregnancy: A Focused Update. (PubMed)

Stroke in Pregnancy: A Focused Update. Ischemic stroke (IS) and hemorrhagic stroke (HS) can be devastating complications during pregnancy and the puerperium that are thought to occur in approximately 30 in 100,000 pregnancies. In high-risk groups, such as women with preeclampsia, the incidence of both stroke subtypes, combined, is up to 6-fold higher than in pregnant women without these disorders. IS or HS may present in young women with atypical symptoms including headache, seizure, extremity (...) weakness, dizziness, nausea, behavioral changes, and visual symptoms. Obstetric anesthesiologists who recognize these signs and symptoms of pregnancy-related stroke are well positioned to facilitate timely care. Acute stroke of any type is an emergency that should prompt immediate coordination of care between obstetric anesthesiologists, stroke neurologists, high-risk obstetricians, nurses, and neonatologists. Historically, guidelines have not addressed the unique situation of maternal stroke

2019 Anesthesia and Analgesia

84. Epidemiology and Treatment of Menstrual Migraine and Migraine During Pregnancy and Lactation: A Narrative Review. (PubMed)

Epidemiology and Treatment of Menstrual Migraine and Migraine During Pregnancy and Lactation: A Narrative Review. The peak prevalence of migraine occurs in women of reproductive age, and women experience a higher burden of migraine symptoms and disability compared to men. This increased burden of migraine in women is related to both developmental and temporally variable activational effects of female sex hormones. Changing levels of female sex hormones affect the expression of migraine during (...) pregnancy, and, to a lesser degree, lactation, and are the mechanism underlying menstrual migraine. This review describes the evidence for sex differences in the expression of migraine across the reproductive epoch; reviews the epidemiology of migraine during pregnancy, lactation, and menses; and summarizes the available evidence for safety and efficacy of acute treatments during pregnancy and lactation and for menstrual migraine. Areas of controversy in treatment of migraine during pregnancy, including

2019 Headache

85. Circadian Rhythm and Attack-timing in Episodic Cluster Headache Patients in- and Outside of Bout: an Actigraphic Study

medication within 2 weeks before the study initiation and during the 2 weeks. Serious somatic and/or psychiatric disorders Alcohol intake > 50 units pr.week Pregnancy / breastfeeding Patient cannot accept the conditions of the trial Patient does not understand Danish. CONTROLS Inclusion Criteria: - Age between 18 and 65 years of age Exclusion Criteria: Circumstances, determined by the PI, that makes the patient ineligible. Any primary headache more than 1 day / month Diagnosed with a secondary headache (...) Circadian Rhythm and Attack-timing in Episodic Cluster Headache Patients in- and Outside of Bout: an Actigraphic Study Circadian Rhythm and Attack-timing in Episodic Cluster Headache Patients in- and Outside of Bout: an Actigraphic Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2016 Clinical Trials

86. Role of Prophylaxis by Oral Fluid Supplementation in Prevention of Postdural Puncture Headache

Role of Prophylaxis by Oral Fluid Supplementation in Prevention of Postdural Puncture Headache Role of Prophylaxis by Oral Fluid Supplementation in Prevention of Postdural Puncture Headache - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Role of Prophylaxis by Oral Fluid Supplementation in Prevention of Postdural Puncture Headache (PROPHYDRA) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02859233 Recruitment Status : Unknown Verified February 2017 by Nantes University Hospital. Recruitment status

2016 Clinical Trials

87. Prazosin for Post-Concussive Headaches

Prazosin for Post-Concussive Headaches Prazosin for Post-Concussive Headaches - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Prazosin for Post-Concussive Headaches The safety and scientific validity (...) brain injuries, people with mTBI can have problems with their memory and concentration. People with mTBI can also find they are more irritable, have more anxiety, and have trouble with their mood and sleep. The purpose of this study is to see if a medication called prazosin can help treat chronic headaches in people with mTBI. The Food and Drug Administration (FDA) has approved prazosin for treating people with high blood pressure. At this time, the FDA has not approved prazosin in the treatment

2016 Clinical Trials

88. Is Detoxification Needed in Medication-overuse Headache?

. Exclusion Criteria: Severe physical illness or psychiatric disorders. Addiction to alcohol or other drugs. Current treatment with headache prophylaxis. Patients can be included minimum 5 weeks after stop of prophylaxis. Pregnancy, breastfeeding or planned pregnancy within the next 12 months. Inability to provide reliable information about medical history. Criteria for Control group 1 - Episodic migraineurs: Episodic migraine, with/without concomitant tension-type headache, according to the ICHD-III beta (...) . Headache days / month ≤ 6 at time of inclusion. Days with analgesics / month ≤ 6 at time of inclusion. Prophylactics are allowed. Age ≥ 18 years old. Ability to fill out headache calendar. No previous medication overuse. No significant co-morbid pain, physical or psychiatric disorders. No addiction to alcohol or drug-abuse. No pregnancy, breastfeeding or planned pregnancy within the next 12 months. Criteria for Control group 2 - Healthy volunteers: •≥ 2 days with headache in the past month at time

2016 Clinical Trials

89. Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department

may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patients who present with a headache or migraine with onset less than or equal to 72 hours Exclusion Criteria: Known pregnancy Breast-feeding women Known history of arrhythmias or QT prolongation (450 ms (...) Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2016 Clinical Trials

90. Thoracic Spine Thrust Manipulation for Cervicogenic Headaches: A Randomized Clinical Trial

Thoracic Spine Thrust Manipulation for Cervicogenic Headaches: A Randomized Clinical Trial Thoracic Spine Thrust Manipulation for Cervicogenic Headaches: A Randomized Clinical Trial - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Thoracic Spine Thrust Manipulation for Cervicogenic Headaches: A Randomized Clinical Trial The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT02708953 Recruitment Status : Recruiting First Posted

2016 Clinical Trials

91. The Association Between Pain Catastrophizing Scale Score and Postspinal Headache

The Association Between Pain Catastrophizing Scale Score and Postspinal Headache The Association Between Pain Catastrophizing Scale Score and Postspinal Headache - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) more. The Association Between Pain Catastrophizing Scale Score and Postspinal Headache The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02727244 Recruitment Status : Completed First Posted : April 4, 2016 Last Update Posted : June 19, 2018 Sponsor: Tokat Gaziosmanpasa University Information provided

2016 Clinical Trials

92. Yoga for Chronic Headache in Adolescents

Yoga for Chronic Headache in Adolescents Yoga for Chronic Headache in Adolescents - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Yoga for Chronic Headache in Adolescents The safety and scientific validity (...) controlled trial to investigate the efficacy of yoga on tension type headache and / or migraine in adolescents between 12 and 16 years, consisting of a four group design which includes an 12 week yoga course and a three-month follow-up period. Both adolescent and one parent will be randomized either to yoga or no treatment. Primary outcome will be pain frequency in adolescents considering pain catastrophizing of parents. Condition or disease Intervention/treatment Phase Tension Type Headache Migraine

2016 Clinical Trials

93. Headache Analysis and Intervention

for eligibility information Ages Eligible for Study: 20 Years to 50 Years (Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria Headache-group: Males and females between 20 and 50 years Confirmed medical diagnosis of tension-type headache, cervicogenic headache or a mixture Headache can be provoked by awkward cervical and/or head postures Exclusion Criteria Headache-group: Pregnancy History of pericranial surgery Serious pathology (neurological/cardiovascular (...) /endocrine/musculoskeletal) Red flags Physical or manual therapy treatment for headache < 4 weeks prior the study Excessive (> 10 days/month for > 3 months) use of: ergotamine, NSAID's, opioids, triptans, acetylsalicylic acid and simple analgesics Psychiatric comorbidity Visual or temporo-mandibular dysfunction Inclusion Criteria Control-group: Males and females between 20 and 50 years Asymptomatic, no headache-history Exclusion Criteria Control-group: Pregnancy History of pericranial surgery Excessive

2016 Clinical Trials

94. Comparison of Two Detoxification Protocols for Treatment of Medication-overuse Headache

Pregnancy or breastfeeding Inadequate language skills to follow the patient education and filling out questionnaires. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02903329 Locations Layout table for location information Denmark Danish Headache Center (...) Comparison of Two Detoxification Protocols for Treatment of Medication-overuse Headache Comparison of Two Detoxification Protocols for Treatment of Medication-overuse Headache - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2016 Clinical Trials

95. Specific Neck Rehabilitation for Unilateral Neck Related Headache and Structural Changes in the Brain

Specific Neck Rehabilitation for Unilateral Neck Related Headache and Structural Changes in the Brain Specific Neck Rehabilitation on Patients With Cervicogenic Headache, and Structural and Functional Changes in the Brain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. Specific Neck Rehabilitation on Patients With Cervicogenic Headache, and Structural and Functional Changes in the Brain The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov

2016 Clinical Trials

96. Evaluation of the Effectiveness and Tolerance of Tetracosactide Synacthen® in the Treatment of Post Dural Puncture Headaches (ESYBRECHE)

Evaluation of the Effectiveness and Tolerance of Tetracosactide Synacthen® in the Treatment of Post Dural Puncture Headaches (ESYBRECHE) Evaluation of the Effectiveness and Tolerance of Tetracosactide Synacthen® in the Treatment of Post Dural Puncture Headaches (ESYBRECHE) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study (...) Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Evaluation of the Effectiveness and Tolerance of Tetracosactide Synacthen® in the Treatment of Post Dural Puncture Headaches (ESYBRECHE) (ESYBRECHE) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your

2016 Clinical Trials

97. Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache.

Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache. Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02746250 Recruitment Status : Completed First Posted : April 21, 2016 Last Update Posted : February 27, 2019

2016 Clinical Trials

98. Buccal Prochlorperazine Versus Intravenous Prochlorperazine for Migraine Headaches, a RCT

Buccal Prochlorperazine Versus Intravenous Prochlorperazine for Migraine Headaches, a RCT Buccal Prochlorperazine Versus Intravenous Prochlorperazine for Migraine Headaches, a RCT - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Buccal Prochlorperazine Versus Intravenous Prochlorperazine for Migraine Headaches, a RCT The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02779959 Recruitment Status : Active, not recruiting First Posted : May 23, 2016 Last Update Posted : January 5, 2018 Sponsor: Los

2016 Clinical Trials

99. IV Haloperidol for the Treatment of Headache in the ED

IV Haloperidol for the Treatment of Headache in the ED IV Haloperidol for the Treatment of Headache in the ED - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. IV Haloperidol for the Treatment of Headache (...) University School of Medicine Study Details Study Description Go to Brief Summary: Single center, double-blind, randomized, placebo-controlled trial evaluating analog pain scores in patients who present to the emergency department (ED) with a complaint of headache. A total of 150 patients age 13-55 presenting to the emergency department with headache will be enrolled from October 2015 - October 2016. Patients will be randomized and pain scores and side effects will be recorded at 0, 30, 60, and 90

2016 Clinical Trials

100. Precutaneous High Risk Patent Foramen Ovale to Treat Migraine Headaches

Precutaneous High Risk Patent Foramen Ovale to Treat Migraine Headaches Precutaneous High Risk Patent Foramen Ovale to Treat Migraine Headaches - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Precutaneous (...) High Risk Patent Foramen Ovale to Treat Migraine Headaches The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT02777359 Recruitment Status : Recruiting First Posted : May 19, 2016 Last Update Posted : July 19, 2017 See

2016 Clinical Trials

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