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Headache in Pregnancy

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41. Behavioral Approaches for Primary Headaches: Recent Advances. (Abstract)

, valuable impact disability and quality of life was observed, as well as improvements in depression, anxiety, self-efficacy, and intake of medications.Behavioral approaches are effective and less prone to produce side or harmful effects, which makes them a valid option particularly for women who are pregnant or nursing, people with other chronic conditions requiring pharmacological treatments putting them at risk for drug-drug interactions, and children.© 2018 American Headache Society. (...) Behavioral Approaches for Primary Headaches: Recent Advances. Behavioral treatments in the management of primary headache disorders in adults and children are increasingly being recognized as effective; however, the level and durability of their effectiveness is still a matter of debate. This review aims to provide more updated information on the effects of behavioral therapies in adults and adolescents with primary headache disorders, with a special focus on new and emerging behavioral

2018 Headache

42. Effect of Infusion of Calcitonin Gene-Related Peptide on Cluster Headache Attacks: A Randomized Clinical Trial. Full Text available with Trip Pro

randomized, double-blind, placebo-controlled, 2-way crossover study set at the Danish Headache Center, Rigshospitalet Glostrup, in Denmark. Analyses were intent to treat. Inclusion took place from December 2015 to April 2017. Inclusion criteria were diagnosis of episodic/chronic cluster headache, patients aged 18 to 65 years, and safe contraception in women. Exclusion criteria were a history of other primary headache (except episodic tension-type headache <5 days/mo), individuals who were pregnant (...) Effect of Infusion of Calcitonin Gene-Related Peptide on Cluster Headache Attacks: A Randomized Clinical Trial. Signaling molecule calcitonin gene-related peptide (CGRP) induces migraine attacks and anti-CGRP medications abort and prevent migraine attacks. Whether CGRP provokes cluster headache attacks is unknown.To determine whether CGRP induces cluster headache attacks in episodic cluster headache in active phase, episodic cluster headache in remission phase, and chronic cluster headache.A

2018 JAMA neurology Controlled trial quality: predicted high

43. Anesthetic approach to postdural puncture headache in the peripartum period: An Israeli national survey. (Abstract)

Anesthetic approach to postdural puncture headache in the peripartum period: An Israeli national survey. Accidental dural puncture frequency among pregnant women is about 1.5%, while approximately 60% of these women will suffer from post-dural puncture headache (PDPH) that may be debilitating.Following IRB approval, we conducted a national survey of the lead anesthesiologist in 23 labor and delivery rooms in Israel. Each survey inquired about medical center annual delivery volume, training

2018 Acta Anaesthesiologica Scandinavica

44. The Efficacy and Safety of Sphenopalatine Ganglion Pulsed Radiofrequency Treatment for Cluster Headache

radiofrequency Additional relevant MeSH terms: Layout table for MeSH terms Headache Cluster Headache Pain Neurologic Manifestations Signs and Symptoms Trigeminal Autonomic Cephalalgias Headache Disorders, Primary Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases (...) Triamcinolone + 2 ml of 1% Bupivacaine + 2 ml of 2% mepivacaine + 1:100000 epinephrine is injected for nerve block treatment using a puncture needle. Outcome Measures Go to Primary Outcome Measures : Duration of the cluster period [ Time Frame: Within 1 year (the cluster period is not over 3 months generally) ] The duration of the cluster period is defined as the total duration of the headache, including the pain attack time before and after treatment. Secondary Outcome Measures : The degree of pain during

2018 Clinical Trials

45. The Role of Inflammation and Vasodilatation in PACAP38-induced Headache Using MRI on Healthy Subjects

Aged 18-50 50-100 kg Exclusion Criteria: Tension type headache more than 5 dag /month Other primary headaches Daily medication except contraceptives Drug taken within 4 times the half-life for the specific drug except contraceptives Pregnant or lactating women Exposure to radiation within the last year Headache within the last 24 hours before start of trial Hypertension Hypotension Respiratory or cardiac disease Primary relatives with current or previous migraine Contacts and Locations Go (...) Product: No Additional relevant MeSH terms: Layout table for MeSH terms Inflammation Headache Pathologic Processes Pain Neurologic Manifestations Signs and Symptoms Ketorolac Ketorolac Tromethamine Sumatriptan Pituitary Adenylate Cyclase-Activating Polypeptide Anti-Inflammatory Agents, Non-Steroidal Analgesics, Non-Narcotic Analgesics Sensory System Agents Peripheral Nervous System Agents Physiological Effects of Drugs Anti-Inflammatory Agents Antirheumatic Agents Cyclooxygenase Inhibitors Enzyme

2018 Clinical Trials

46. Continuous Positive Airway Pressure as a Potential New Treatment for Cluster Headache

3.1.2. is able to separate cluster headache attacks from other types of headache. agrees to maintain current preventive headache and sleep medication regimens (no change in type, frequency, or dose) during the whole study period. Signed informed consent. Exclusion Criteria: disorders with contraindications for use of continuous positive airway pressure (e.g. unable to remove the ventilation mask due to a movement disorders). Nightly cluster headache attacks Pregnancy or planned pregnancy having had (...) a change in type, dosage or dose frequency of preventive headache or sleep medications < 1 months prior to inclusion. Severe depression or other psychiatric disorder that may interfere with the treatment. Abuse of alcohol or illicit drugs. Other severe chronic pain conditions Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please

2018 Clinical Trials

47. Neuroinflammatory Response and Headache Control in Patients After Subarachnoid Hemorrhage

First Posted : July 27, 2018 Last Update Posted : July 27, 2018 See Sponsor: Maine Medical Center Information provided by (Responsible Party): Elizabeth Glisic, Maine Medical Center Study Details Study Description Go to Brief Summary: The purpose of this study is to determine the relationship between the Neuroinflammatory response and headache pain after subarachnoid hemorrhage. Condition or disease Subarachnoid Hemorrhage, Aneurysmal Headache Subarachnoid Hemorrhage Detailed Description: Persistent (...) to determine the magnitude and dynamics of their neuroinflammatory response. In addition, the investigators will collect and analyze observational data about the success of medications to treat headache, with a specific focus on the anti-inflammatory agent dexamethasone, in managing acute headache pain and preventing the development of persistent headaches in patients after SAH. Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 40 participants

2018 Clinical Trials

48. Reproductive Headache? Investigating Acetaminophen as a Potential Endocrine Disruptor Full Text available with Trip Pro

Animals Endocrine Disruptors therapeutic use Female Headache drug therapy Humans Male Pregnancy Reproduction drug effects 2017 07 06 2017 07 06 2018 3 13 6 0 2018 3 13 6 0 2019 2 5 6 0 epublish 29529598 10.1289/EHP2478 EHP2478 PMC6071750 Paediatr Perinat Epidemiol. 2012 Sep;26(5):456-67 22882790 Schizophr Res. 2011 Mar;126(1-3):220-5 21146371 Int J Epidemiol. 2016 Dec 1;45(6):1987-1996 27353198 Hum Reprod. 2016 Sep;31(9):2119-27 27412248 Toxicol Sci. 2016 Mar;150(1):178-89 26732887 Arch Dis Child (...) Reproductive Headache? Investigating Acetaminophen as a Potential Endocrine Disruptor 29529598 2019 02 04 2019 02 15 1552-9924 126 3 2018 03 09 Environmental health perspectives Environ. Health Perspect. Reproductive Headache? Investigating Acetaminophen as a Potential Endocrine Disruptor. 032001 10.1289/EHP2478 Konkel Lindsey L eng Journal Article 2018 03 09 United States Environ Health Perspect 0330411 0091-6765 0 Endocrine Disruptors 362O9ITL9D Acetaminophen IM Acetaminophen therapeutic use

2018 Environmental health perspectives

49. SubArachnoid Hemorrhage HEadache Treated by Lumbar Puncture

: University Hospital, Toulouse Information provided by (Responsible Party): University Hospital, Toulouse Study Details Study Description Go to Brief Summary: Headache control is one of the major challenges in patients who suffered an acute aneurysmal subarachnoid hemorrhage (aSAH). Headache affects 90% of the patient and is resistant to the major pain medication. It results from the increased intracranial pressure and the inflammation caused by the accumulation of arterial blood in the subarachnoid space (...) Aneurysmal Subarachnoid Hemorrhage Headache Procedure: Lumbar puncture Not Applicable Detailed Description: After aneurysmal subarachnoid hemorrhage (aSAH) almost 90 % of patients experience a severe headache during their hospital stay. Pain control often requires high doses of opioid drugs and sedation that remain only partially efficacious. In addition, there is to the investigator's knowledge currently no recommendation or consensus on aSAH related headache management. aSAH related headache results

2018 Clinical Trials

50. Endogenous Modulation and Central Sensitization in New Daily Persistent Headache ( NDPH ) in Children

Recruitment Status : Recruiting First Posted : February 27, 2018 Last Update Posted : July 30, 2018 See Sponsor: Boston Children’s Hospital Information provided by (Responsible Party): Alyssa Lebel, MD, Boston Children’s Hospital Study Details Study Description Go to Brief Summary: New daily persistent headache (NDPH) is a primary headache disorder characterized by the daily and unremitting headache pain patients experience with a distinct onset. Despite the known significant impairment associated (...) or disease Intervention/treatment Phase New Daily Persistent Headache (NDPH) Drug: Naltrexone HCl (Bulk) Powder Phase 1 Phase 2 Detailed Description: The purpose of this study is to investigate low-dose naltrexone for the treatment of new daily persistent headache (NDPH) in adolescents ages 10-17. New daily persistent headache (NDPH) is a primary headache disorder characterized by continuous pain experienced for at least 3 months from distinct onset. Patients with NDPH have compromised academic

2018 Clinical Trials

51. Headaches Through a Woman's Life. (Abstract)

Headaches Through a Woman's Life. Headaches affect women across their life span, with menses, pregnancy, and menopause being times that pose unique challenges in diagnosis and treatment. The correct diagnosis and treatment of headache can prevent unnecessary interventions, the worsening of chronic headache disorders, and complications of secondary headaches.The objective of this article is to educate women's health care providers about the diagnosis, differential diagnosis, and treatment (...) of headache during menses, pregnancy, the puerperium, and menopause to improve the quality of care for women with chronic and acute headache.Current articles were reviewed addressing headache during menses, pregnancy, the postpartum period, and menopause. Articles with the highest level of evidence were compiled in this article to provide a summary of recommendations.Multiple diagnostic and therapeutic options for chronic and acute headache are available for women regardless of their stage in life

2018 Obstetrical & Gynecological Survey

52. Comparison of Effects of Peripheral Nerve Block and Topiramate in the Treatment of Medication Overuse Headaches

and older (Child, Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Chronic migraine diagnosis according to International Classification of Headache-2 Disorders (ICHD) w/o pregnancy or breastfeeding. w/o acute or chronic psychiatric disorders. w/o nephrolithiasis. w/o medication of anticoagulant and antiaggregant. w/o allergy to topiramate or bupivacaine. w/o prophylaxis within the last three months with any of; propranolol, nebivolol (...) Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Mustafa Ceylan, Ataturk University: Medication overuse headache; Greater occipital nerve block; supratrochlear nerve block; topiramate. Additional relevant MeSH terms: Layout table for MeSH terms Headache Headache Disorders, Secondary Pain Neurologic Manifestations Signs and Symptoms Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Topiramate Anticonvulsants Hypoglycemic

2018 Clinical Trials

53. Hypertension in pregnancy: diagnosis and management

Reducing the risk of hypertensive disorders in pregnancy Symptoms of pre-eclampsia Symptoms of pre-eclampsia 1.1.1 Advise pregnant women to see a healthcare professional immediately if they experience symptoms of pre-eclampsia. Symptoms include: severe headache problems with vision, such as blurring or flashing before the eyes severe pain just below the ribs vomiting sudden swelling of the face, hands or feet. See the NICE guideline on antenatal care for advice on risk factors and symptoms of pre (...) are in a critical care setting if birth is planned within 24 hours. [2010] [2010] 1.8.3 Consider the need for magnesium sulfate treatment, if 1 or more of the following features of severe pre-eclampsia is present: ongoing or recurring severe headaches visual scotomata nausea or vomiting epigastric pain oliguria and severe hypertension Hypertension in pregnancy: diagnosis and management (NG133) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

54. Ectopic pregnancy and miscarriage: diagnosis and initial management

and miscarriage: diagnosis and initial management (NG126) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 3 of 33This guideline replaces CG154. This guideline is the basis of QS69. Ov Overview erview This guideline covers diagnosing and managing ectopic pregnancy and miscarriage in women with complications, such as pain and bleeding, in early pregnancy (that is, up to 13 completed weeks of pregnancy). It aims to improve how (...) for an ultrasound scan Ectopic pregnancy and miscarriage: diagnosis and initial management (NG126) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 5 of 33what to expect during the course of her care (including expectant management), such as the potential length and extent of pain and/or bleeding, and possible side effects. This information should be tailored to the care she receives information about post-operative care

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

55. Headache in Pregnancy: An Approach to Emergency Department Evaluation and Management Full Text available with Trip Pro

Headache in Pregnancy: An Approach to Emergency Department Evaluation and Management Headache is a common presenting complaint in the emergency department. The differential diagnosis is broad and includes benign primary causes as well as ominous secondary causes. The diagnosis and management of headache in the pregnant patient presents several challenges. There are important unique considerations regarding the differential diagnosis, imaging options, and medical management. Physiologic changes (...) induced by pregnancy increase the risk of cerebral venous thrombosis, dissection, and pituitary apoplexy. Preeclampsia, a serious condition unique to pregnancy, must also be considered. A high index of suspicion for carbon monoxide toxicity should be maintained. Primary headaches should be a diagnosis of exclusion. When advanced imaging is indicated, magnetic resonance imaging (MRI) should be used, if available, to reduce radiation exposure. Contrast agents should be avoided unless absolutely

2015 Western Journal of Emergency Medicine

56. The Role of Headache in the Classification and Management of Hypertensive Disorders in Pregnancy. (Abstract)

The Role of Headache in the Classification and Management of Hypertensive Disorders in Pregnancy. Hypertensive disorders of pregnancy remain among the leading causes of maternal morbidity and mortality. The onset of headaches in patients with hypertensive disorders of pregnancy has been considered as a premonitory symptom for eclampsia and other adverse maternal outcomes. Headaches are very common symptoms during pregnancy and the postpartum period with a reported incidence of 39%; however (...) , headache is absent in 30-50% of women before the onset of eclampsia and is a poor predictor of eclampsia and adverse maternal outcomes. If included in the definition of cerebral or visual disturbances, headache may be considered a symptom of preeclampsia, a diagnostic feature of preeclampsia with severe features, a premonitory symptom of eclampsia, and an indication for delivery. Inclusion of this nonspecific symptom in the diagnosis and management of hypertensive disorders of pregnancy in the absence

2015 Obstetrics and Gynecology

57. Coronavirus (COVID-19) infection and pregnancy

Coronavirus (COVID-19) infection and pregnancy 1 Information for healthcare professionals Version 9: Published Wednesday 13 May 2020 Coronavirus (COVID-19) Infection in Pregnancy2 Contents Summary of updates 3-5 1. Introduction 6-11 2. Advice for health professionals to share with pregnant women 12-19 3. Advice for all midwifery and obstetric services caring for pregnant women 20-36 4. Advice for services caring for women with suspected or confirmed COVID-19 37-39 Acknowledgements 40 Appendix 1 (...) for antibiotics at presentation, with early review and rationalisation of antibiotics if COVID-19 is confirmed.’ 9 13.5.20 3.6: Statement added: ‘A woman with moderate or severe COVID symptoms who happens to be pregnant but with no immediate pregnancy issue should be cared for by the same multidisciplinary team as a non-pregnant woman with additional input from the maternity team. The labour ward should not be the default location for all pregnant women.’6 1. Introduction7 1. Introduction The following advice

2020 Royal College of Obstetricians and Gynaecologists

58. Coronavirus (COVID-19) infection and pregnancy

with or for COVID-19. 15 Similar findings were reported in a large systematic review of 2,567 pregnancies with COVID-19, where 50.8% of women were from a BAME background. 38.2% of the women were obese and 32.5% had chronic comorbidities such as asthma and hypertension. 28 The association with BAME is particularly apparent and echoes previous findings that UK BAME pregnant women generally have worse outcomes in pregnancy and birth. 23 Furthermore, 13% of the UK’s total population identifies as being from a BAME (...) affects 5% of pregnant women in the UK, with the majority (88%) of women with diabetes in pregnancy affected by gestational diabetes. 39 In the UKOSS study, comorbidities such as diabetes were associated with pregnant women being admitted to hospital with COVID-19. 15 In non-pregnant individuals, a UK study of 20,133 patients admitted to high dependency and intensive care with COVID-19 found uncomplicated diabetes was one of the most common comorbidities (21%, 3650/17599); a further 7% (n=1299

2020 Royal College of Obstetricians and Gynaecologists

59. Coronavirus (COVID-19) infection and pregnancy

professionals based on a combination of available evidence, good practice and expert consensus opinion. The priorities are: (i) The reduction of transmission of COVID-19 to pregnant women. (ii) The provision of safe, personalised and woman-centred care during pregnancy, birth and the early postnatal period during the COVID-19 pandemic. (iii) The provision of safe, personalised and woman-centred care to pregnant and postnatal women with suspected/confirmed COVID-19. Please be aware that this is very much (...) clinical advice or information for specific organisational requirements via this email address. Information for pregnant women and their families is available in question and answer format, with accompanying videos in some cases, on the RCOG COVID-19 hub. 1.1 Identification and assessment of evidence This guidance document is updated regularly following a review of the evolving literature during this pandemic. Weekly literature reviews are generated using the following search terms, MESH headings

2020 Royal College of Obstetricians and Gynaecologists

60. NZSHS Syphilis in Pregnancy Guideline

10.2.2 Late syphilis in pregnancy and syphilis of unknown duration (all three trimesters) . 14 10.2.3 Neurosyphilis (all trimesters) 14 10.3 Special considerations 15 10.3.1 Syphilis infection treated prior to pregnancy 15 10.3.2 Penicillin allergy 15 10.3.3 Syphilis diagnosis > 20 weeks of pregnancy 16 10.3.4 Jarisch-Herxheimer (JH) reaction 16 10.3.5 HIV positive pregnant woman with syphilis 17 10.3.6 Management of sexual contacts and other children 17 Syphilis in Pregnancy Sept 2020 V1 3 Table 2 (...) 17 10.3.7 Management of pregnant sexual contacts of infectious syphilis 17 10.3.8 Follow up 18 10.3.9 Labour and birth 19 10.3.10 Contact Precautions 19 10.3.11 Handling of placenta (whenua) 19 11. Care of the new-born (birth to 1 month) 20 11.1 Infant assessment and management summary (infants 2 years since acquisition with no symptoms) and tertiary syphilis (symptomatic late syphilis e.g. gummas, cardiovascular and neurological involvement). Syphilis in Pregnancy Sept 2020 V1 8 Primary syphilis

2020 New Zealand Sexual Health Society

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