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Headache in Pregnancy

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21. Neuromodulation for the Acute and Preventive Therapy of Migraine and Cluster Headache. Full Text available with Trip Pro

as safe and effective acute and preventive treatment options. In this review, we focus on neuromodulation devices that have been studied for migraine and cluster headache, with special attention to those that have gained food and drug administration (FDA) clearance. We will also explore how these devices can be used in patients who might have limited pharmacologic options, including the elderly, children, and pregnant women.© 2019 American Headache Society. (...) Neuromodulation for the Acute and Preventive Therapy of Migraine and Cluster Headache. Headache disorders are among the most common and disabling medical conditions worldwide. Pharmacologic acute and preventive treatments are often insufficient and poorly tolerated, and the majority of patients are unable to adhere to their migraine treatments due to these issues. With improvements in our understanding of migraine and cluster headache pathophysiology, neuromodulation devices have been developed

2019 Headache

22. A 32-Year-Old Woman With Miscarriage, Headache, Hepatitis, and Pulmonary Disease. Full Text available with Trip Pro

A 32-Year-Old Woman With Miscarriage, Headache, Hepatitis, and Pulmonary Disease. A 32-year-old Nigerian woman, who became pregnant after undergoing in vitro fertilization, was admitted with nausea and abdominal pain. She had a history of two miscarriages and infertility because of tubal blockage treated by salpingectomy. One week prior, she presented to an outside hospital with premature rupture of membranes resulting in stillborn delivery of twins. Endometrial cultures from dilatation

2019 Chest

23. Headache - cluster

listed below should be considered: Headache not associated with an underlying condition – primary headache: Migraine . Tension-type headache . Trigeminal autonomic cephalalgias other than cluster headache such as paroxysmal hemicranias. Other primary headache disorders such as primary cough headache and cold-stimulus headache. Secondary headachesheadache attributed to an underlying condition including: Trauma or injury to the head and/or neck . Cranial or cervical vascular disorders for example (...) Headache - cluster Headache - cluster - NICE CKS Share Headache - cluster: Summary Cluster headache is a rare but severe primary headache disorder — it is the most common trigeminal autonomic cephalalgia. It is characterized by: Recurrent attacks of one-sided pain, in or around the eye or temporal region. Ipsilateral autonomic symptoms such as conjunctival injection and/or lacrimation, nasal congestion and/or rhinorrhoea, eyelid oedema, forehead and facial sweating or flushing. Brief attacks

2017 NICE Clinical Knowledge Summaries

24. Headache - assessment

. Trigeminal autonomic cephalgias such as cluster headache. Other primary headache disorders such as primary cough headache or cold-stimulus headache. Secondary headachesheadaches which occur as a result of underlying local or systemic pathology for example: Trauma or injury to the head and/or neck. Cranial or cervical vascular disorders such as intracerebral haemorrhage, central venous thrombosis or giant cell arteritis. Non-vascular intracranial disorders such as idiopathic intracranial hypertension (...) such as primary cough headache and cold-stimulus headache. Secondary headachesheadache attributed to an underlying condition including: Trauma or injury to the head and/or neck . Cranial or cervical vascular disorders for example intracerebral haemorrhage, central venous thrombosis or giant cell arteritis. Non-vascular intracranial disorders for example idiopathic intracranial hypertension or neoplasm. Exposure to, or withdrawal from, a substance such as carbon monoxide, cocaine or alcohol — medication

2017 NICE Clinical Knowledge Summaries

25. Effect of pre-administration with aminophylline on the occurrence of post-dural puncture headache in women undergoing caesarean section by combined spinal-epidural anaesthesia. Full Text available with Trip Pro

Effect of pre-administration with aminophylline on the occurrence of post-dural puncture headache in women undergoing caesarean section by combined spinal-epidural anaesthesia. To investigate the effect of the pre-administration with aminophylline on the occurrence of post-dural puncture headache (PDPH) in women undergoing caesarean section by combined spinal-epidural anaesthesia (CSEA).The study enrolled women undergoing elective caesarean sections with CSEA and randomly allocated them (...) aminophylline administration.A total of 120 patients aged 24-38 years (pregnancy range, 38-42 weeks) were randomly allocated into two groups ( n = 60). The incidence of PDPH in group A was significantly lower than group C (two of 59 [3.4%] versus 10 of 58 [17.2%], respectively). There were no related side-effects within 24 h after aminophylline administration in group A.Intraoperative intravenous infusion of 250 mg aminophylline reduced the incidence of PDPH after caesarean section under CSEA with no side

2018 The Journal of international medical research Controlled trial quality: uncertain

26. Red and orange flags for secondary headaches in clinical practice: SNNOOP10 list. Full Text available with Trip Pro

: (1) systemic symptoms including fever; (2) neoplasm history; (3) neurologic deficit (including decreased consciousness); (4) sudden or abrupt onset; (5) older age (onset after 65 years); (6) pattern change or recent onset of new headache; (7) positional headache; (8) precipitated by sneezing, coughing, or exercise; (9) papilledema; (10) progressive headache and atypical presentations; (11) pregnancy or puerperium; (12) painful eye with autonomic features; (13) posttraumatic onset of headache; (14 (...) Red and orange flags for secondary headaches in clinical practice: SNNOOP10 list. A minority of headache patients have a secondary headache disorder. The medical literature presents and promotes red flags to increase the likelihood of identifying a secondary etiology. In this review, we aim to discuss the incidence and prevalence of secondary headaches as well as the data on sensitivity, specificity, and predictive value of red flags for secondary headaches. We review the following red flags

2018 Neurology

27. Prediction of Post-dural Puncture Headache in Parturients Undergoing Elective Caesarean Section

a compensatory reflex vasodilatation occur in the same pain sensitive blood vessels and this result in pain. The association of common risk factors like female gender, particularly females during pregnancy, age groups of 20 - 40 years, a prior history of chronic headache, and a lower body mass index expose the patient to PDPH. The identification of factors that predict the likelihood of PDPH is important so that measures can be taken to minimize this painful complication resulting from spinal anesthesia (...) develops between 5 and 14 days after the technique however it may immediately occur after dural puncture but it is rare and should pay attention of the physician to alternative causes. The pain is increased by head movement, upright posture and relieved by lying down. It resolves either spontaneously within 7 days or within 48 h after effective treatment which is usually consists of fluid therapy, analgesics, sumatriptan and caffeine. Epidural blood patch remained the gold standard therapy

2018 Clinical Trials

28. Primary Headache and Psychological Factors, Mental Functioning and Attachment Modalities.

is concerned. WHO estimates that 1.7-4% of the global adult population is affected by headache for at least 15 days a month. Headaches are disabling, for patients (pain, suffering, fatigue, unavailability ...) but also for society (socio-economic cost as frequent work stoppages and drug costs). They are a public health problem. In 2002, the High Authority of Health published its recommendations for the diagnosis and management of migraine patients. In addition, the French Society for Migraine and Headache (...) table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Centre Hospitalier Universitaire de Besancon: psychological factors Additional relevant MeSH terms: Layout table for MeSH terms Headache Headache Disorders Headache Disorders, Primary Pain Neurologic Manifestations Signs and Symptoms Brain Diseases Central Nervous System Diseases Nervous System Diseases

2018 Clinical Trials

29. A Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache

research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 65 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: Age 18 to 65 years Presenting chief complaint of headache, migraine, tension headache, cluster headache, or headache not otherwise specified Report of pain 4 using a standard 11-point numerical scale (0 to 10; 0=no pain and 10=worst (...) possible pain) Exclusion Criteria: Age < 18 years or > 65 years Inability to provide informed consent Physical or mental disability hindering adequate response to assessment of pain Hemodynamic instability/medical condition requiring acute life-saving medical intervention Documented or suspected pregnancy or currently breastfeeding Known brain mass, intracranial hemorrhage, skull fracture Known allergy, hypersensitivity, or prior adverse reaction to acetaminophen, NSAIDs, diphenhydramine

2018 Clinical Trials

30. Two Fluid Strategies for Prevention of Post-dural Puncture Headache

Go to Primary Outcome Measures : Incidence of post-dural puncture headache [ Time Frame: 48 hours ] the number of patients who develop post-dural puncture headache defined as pain scale above 4 Secondary Outcome Measures : incidence of post-spinal hypotension [ Time Frame: 60 minutes ] number of patients who develop hypotension defined as decrease of systolic blood pressure by more than 20% from the baseline reading after subarachnoid block Wong-Baker faces pain scale [ Time Frame: 48 hours (...) Criteria: History of migraine headache Hypertensive disorders of pregnancy Cardiac morbidities, Baseline systolic blood pressure < 100 mmHg Contraindication of regional anesthesia. Patients with more than one single attempt for spinal block Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its

2018 Clinical Trials

31. Testing myWHI: Online Self-help Programs for Headaches

of four headache days during 4 weeks that they are asked to use an electronic headache diary Exclusion criteria: health care professional has not ruled out any underlying medical condition related to their headaches (e.g., head trauma, meningitis) are pregnant, planning to get pregnant (in the next 4 to 6 months), or breastfeeding, as hormonal changes are known to exert potent influences on migraine headaches have an impairment which compromises their ability to give informed consent having been (...) Testing myWHI: Online Self-help Programs for Headaches Testing myWHI: Online Self-help Programs for Headaches - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Testing myWHI: Online Self-help Programs

2018 Clinical Trials

32. PACAP27 Headache Properties in Migraine Without Aura Patients

either Intra Uterine Device (IUD), birth control pills, surgical sterilization of the woman or depot progestogen. Exclusion Criteria: Tension Type headache for more than 5 days the month on average in the last year. All other primary headaches . Headache later than 48 hours before trial start. Daily intake of any medicine other than oral contraception. Ingestion of any form of medicinal product later than 4 times the plasma half-life substance (on trial day), except for oral contraception. Pregnant (...) Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Migraine Disorders Headache Migraine without Aura Headache Disorders, Primary Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Pain Neurologic Manifestations Signs and Symptoms Pituitary Adenylate Cyclase-Activating Polypeptide Growth Substances Physiological Effects

2018 Clinical Trials

33. Using the S100B Protein for Emergency Headache Management Care

/10 Blood sample can be taken within 1 hour following the emergency admission VAS > 6 or Glasgow < 8 Signed and dated informed consent by patient, or trusted person, or family Exclusion Criteria: Patient presenting headache after head trauma Pregnant or breastfeeding women Patient with a pathology causing the elevation of PS100B's rate such as Alzheimer's disease, Creuzfeld-Jacob's disease, Multiple Sclerosis, cerebral tumour, trisomy 21, melanoma (diabetes excluded) Patient covered by social (...) negative predictive value headache intracranial hemorrhage Additional relevant MeSH terms: Layout table for MeSH terms Emergencies Hemorrhage Headache Migraine Disorders Disease Attributes Pathologic Processes Pain Neurologic Manifestations Signs and Symptoms Headache Disorders, Primary Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases

2018 Clinical Trials

34. Salivary Inflammatory Markers in Tension Type Headache and Migraine

International Classification of Headache Disorders, 3rd edition (beta version) Exclusion Criteria: abnormal plasma CRP, Interleukin-1β and Interleukin-6 levels (>10 mg/L) smoking cigarettes > 1 pack/day; current pregnancy, lactation, or hormonal contraceptive use alcohol or substance abuse drug use such as anticoagulants, statins, or hormonal drugs anti-inflammatory therapy other primary or secondary headaches major psychiatric disease oral health problems. Contacts and Locations Go to Information from (...) headaches CRP Interleukin1β Interleukin6 markers Additional relevant MeSH terms: Layout table for MeSH terms Migraine Disorders Headache Tension-Type Headache Headache Disorders, Primary Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Pain Neurologic Manifestations Signs and Symptoms

2018 Clinical Trials

35. Effectiveness of Dry Needling of the Sternocleidomastoid in Patients With Cervicogenic Headaches

of this study is to determine whether individuals with cervicogenic headache respond favorably to a program of manual therapy in combination with dry needling of the major muscle between chest bone and the head (sternocleidomastoid muscle) compared to manual therapy directed to the upper body quadrant alone. The researchers will conduct a randomized clinical trial to assess the effectiveness of a manual therapy and dry needling approach (group 1) vs. manual therapy only. (group 2) Study Design Go to Layout (...) spine Chiropractic, Physical Therapy, or Acupuncture treatment for their neck pain in the last 6-months Workers compensation or pending legal action regarding their headaches Insufficient English language skills to complete all questionnaires Inability to comply with treatment and follow-up schedule Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information

2018 Clinical Trials

36. A Study to Describe Pain Intensity, Pain Relief and Safety of Neosaldina in the Treatment of Tension-type Headaches (TTH) in Healthy Participants

A Study to Describe Pain Intensity, Pain Relief and Safety of Neosaldina in the Treatment of Tension-type Headaches (TTH) in Healthy Participants A Study to Describe Pain Intensity, Pain Relief and Safety of Neosaldina in the Treatment of Tension-type Headaches (TTH) in Healthy Participants - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study to Describe Pain Intensity, Pain Relief and Safety of Neosaldina in the Treatment of Tension-type Headaches (TTH) in Healthy Participants The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk

2018 Clinical Trials

37. rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head

rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head (TOPiCS-rTMS) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03691272 Recruitment Status : Active

2018 Clinical Trials

38. Ondansetron 8 mg and 4 mg with normal saline against post-operative headache and nausea/vomiting after spinal anesthesia: a randomized double-blind trial Full Text available with Trip Pro

Ondansetron 8 mg and 4 mg with normal saline against post-operative headache and nausea/vomiting after spinal anesthesia: a randomized double-blind trial The study aims to evaluate the efficacy of ondansetron in preventing post-spinal headache, considering the high prevalence of the headache in pregnant women and the common use of the adjuvants for prophylaxis against post-operative nausea and vomiting (PONV). This double-blind clinical trial included the 195 patients who were referred (...) to Taleghani Hospital (in Arak, Iran) for cesarean section (C/S) under spinal anesthesia, and then the subjects were assigned to three equally sized groups using block randomization. Participants in the first, second, and control groups received 8 mg, 4 mg of ondansetron, and normal saline, respectively, 5 minutes before surgery. A final volume of 5 cc was prepared by adding normal saline. Participants were examined for headache one week after surgery, and then data analysis was performed using SPSS 20

2018 Medical gas research Controlled trial quality: predicted high

39. Behavioral Approaches for Primary Headaches: Recent Advances. (Abstract)

, valuable impact disability and quality of life was observed, as well as improvements in depression, anxiety, self-efficacy, and intake of medications.Behavioral approaches are effective and less prone to produce side or harmful effects, which makes them a valid option particularly for women who are pregnant or nursing, people with other chronic conditions requiring pharmacological treatments putting them at risk for drug-drug interactions, and children.© 2018 American Headache Society. (...) Behavioral Approaches for Primary Headaches: Recent Advances. Behavioral treatments in the management of primary headache disorders in adults and children are increasingly being recognized as effective; however, the level and durability of their effectiveness is still a matter of debate. This review aims to provide more updated information on the effects of behavioral therapies in adults and adolescents with primary headache disorders, with a special focus on new and emerging behavioral

2018 Headache

40. Effect of Infusion of Calcitonin Gene-Related Peptide on Cluster Headache Attacks: A Randomized Clinical Trial. Full Text available with Trip Pro

randomized, double-blind, placebo-controlled, 2-way crossover study set at the Danish Headache Center, Rigshospitalet Glostrup, in Denmark. Analyses were intent to treat. Inclusion took place from December 2015 to April 2017. Inclusion criteria were diagnosis of episodic/chronic cluster headache, patients aged 18 to 65 years, and safe contraception in women. Exclusion criteria were a history of other primary headache (except episodic tension-type headache <5 days/mo), individuals who were pregnant (...) Effect of Infusion of Calcitonin Gene-Related Peptide on Cluster Headache Attacks: A Randomized Clinical Trial. Signaling molecule calcitonin gene-related peptide (CGRP) induces migraine attacks and anti-CGRP medications abort and prevent migraine attacks. Whether CGRP provokes cluster headache attacks is unknown.To determine whether CGRP induces cluster headache attacks in episodic cluster headache in active phase, episodic cluster headache in remission phase, and chronic cluster headache.A

2018 JAMA neurology Controlled trial quality: predicted high

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