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Headache in Pregnancy

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261. The Effect of Patient Position on Postdural Puncture Headache

ÖZTÜRK, Diskapi Yildirim Beyazit Education and Research Hospital Study Details Study Description Go to Brief Summary: We aimed to investigate the association between the position in which spinal anesthesia was performed and postdural puncture headache occurrence. Condition or disease Intervention/treatment Pregnancy Headache Other: lateral Other: sitting Detailed Description: Records of patients who underwent caesarean section between January, 2013 and November, 2013 with spinal anesthesia (...) Headache Post-Dural Puncture Headache Pain Neurologic Manifestations Signs and Symptoms Headache Disorders, Secondary Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Anesthetics Central Nervous System Depressants Physiological Effects of Drugs

2014 Clinical Trials

262. The Efficacy of L-cysteine in Prevention of Headache Attacks in Migraine Patients

: Layout table for MeSH terms Migraine Disorders Headache Headache Disorders, Primary Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Pain Neurologic Manifestations Signs and Symptoms (...) The Efficacy of L-cysteine in Prevention of Headache Attacks in Migraine Patients The Efficacy of L-cysteine in Prevention of Headache Attacks in Migraine Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding

2014 Clinical Trials

263. The Efficacy of L-cysteine in Prevention of Cluster Headache

Posted: January 17, 2019 Last Verified: January 2019 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Keywords provided by Biohit Oyj: Cluster headache Migrainous neuralgia Horton's headache Histaminic cephalalgia Additional relevant MeSH terms: Layout table for MeSH terms Headache Cluster Headache Pain Neurologic Manifestations Signs and Symptoms Trigeminal Autonomic Cephalalgias Headache Disorders, Primary Headache Disorders Brain Diseases Central Nervous System Diseases (...) fertile and sexually active women who do not practise contraception other acute or chronic pain disorders severe psychiatric disease infections malignancy short life expectancy cardiovascular disease cerebrovascular disease uncontrolled hypertension degenerative central nervous system diseases pregnant and lactating women regular users of Acetium capsules for other indications renal dysfunction or cystinuria Contacts and Locations Go to Information from the National Library of Medicine To learn more

2014 Clinical Trials

264. Haldol/Diphenhydramine Versus Metoclopramide/Diphenhydramine for Treatment of Acute Headache in the Emergency Department: A Randomized Controlled Trial

intervals using a 100mm visual analog scale (VAS). Adequate pain control was considered to be patient satisfaction with symptomatic relief. If adequate pain relief was not obtained after 80 minutes, rescue medication was given at the treating physician's discretion. Adverse reactions were recorded and electrocardiograms (ECGs) were obtained before and after study medication administration. Follow up phone surveys were performed 72 hours after discharge to assess headache recurrence, adverse effects (...) anti-emetic within the past 24 hrs Concurrent administration or within 2 weeks of discontinuing an MAO inhibitor Concurrent management of hemiplegic or basilar migraine or known neurologic disorder Severe hepatic impairment Pregnancy or breastfeeding History of cancer (except non-melanoma skin cancer) Previous involvement in the study Febrile to 100.5 or greater Any indication for further diagnostic evaluation of this headache such as a lumbar puncture or CT scan. Headache differs from their normal

2014 Clinical Trials

265. Carbon Monoxide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow

table for eligibility information Ages Eligible for Study: 18 Years to 50 Years (Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: Healthy volunteers Aged 18-50 50-100 kg Exclusion Criteria: Tension type headache more than once/month Other primary headaches Daily medication except contraceptives Drug taken within 4 times the halflife for the specific drug except contraceptives Pregnant or lactating women Exposure to radiation within the last year (...) Last Update Posted: February 12, 2015 Last Verified: February 2015 Keywords provided by Nanna Arngrim, Danish Headache Center: Carbon monoxide Headache Migraine Additional relevant MeSH terms: Layout table for MeSH terms Migraine Disorders Headache Headache Disorders, Primary Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Pain Neurologic Manifestations Signs and Symptoms Carbon Monoxide Antimetabolites Molecular Mechanisms of Pharmacological Action

2014 Clinical Trials

266. Pilot Study of VVD-101 for the Treatment of Delayed Alcohol-Induced Headaches

to Complete Pain Freedom at Two Hours Post Treatment [ Time Frame: Immediately Prior to Treatment to 2 Hours Post Treatment ] Number of headaches relieved (no head pain) at 2 hours post treatment for VVD-101 vs. placebo. Headache severity was measured on a 4 point Likert scale with 0 = no pain, 1 = mild pain, 2 = moderate, 3 = severe pain. Number of Headaches With Sustained Pain Freedom at Twenty Four Hours Post Treatment [ Time Frame: Time of Treatment to 24 Hours Post Treatment ] Number of headaches (...) , nose, throat (ENT) disorders, or psychiatric disorders, cranial or cervical disorders or neuralgias) within the previous year. significant alcohol or drug use problems (score > 4 on the Simple Screening Instrument for Alcohol and Other Drugs (SSI-AOD)) or history of treatment or counseling for alcohol or drug abuse and or dependence. used acute headache medication including non-prescription medications, 15 or more days per month during the last 3 months. pregnant, actively trying to become pregnant

2014 Clinical Trials

267. IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Migraine and/or Episodic Tension-type Headache and Patients' Satisfaction With the Treatment in Routine Clinical Practice

Date : November 2015 Actual Study Completion Date : November 2015 Resource links provided by the National Library of Medicine related topics: related topics: Groups and Cohorts Go to Group/Cohort primary headaches Adults taking IndoProCaf for acute treatment of their primary headache attacks (migraine and/or episodic tension-type headache) as per routine clinical practice Outcome Measures Go to Primary Outcome Measures : Percentage of Patients With Significant Pain Reduction [ Time Frame: up to 2 (...) hours ] significant pain reduction defined as improvement to mild or no pain 2 hours post-dose by 4-point pain severity scale: 0 = no pain; 1 = mild headache, allowing normal activities; 2 = moderate headache, disturbing normal activities; 3 = severe headache, disabling activities, requiring bed-rest Percentage of Patients Who Are Satisfied With IndoProCaf Treatment [ Time Frame: up to 24 hours post dose ] Patients are asked to evaluate their satisfaction with headache pain reduction after treatment

2014 Clinical Trials

268. R-Verapamil for the Prophylaxis of Episodic Cluster Headache

relevant MeSH terms: Layout table for MeSH terms Headache Cluster Headache Pain Neurologic Manifestations Signs and Symptoms Trigeminal Autonomic Cephalalgias Headache Disorders, Primary Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Verapamil Anti-Arrhythmia Agents Calcium Channel Blockers Membrane Transport Modulators Molecular Mechanisms of Pharmacological Action Calcium-Regulating Hormones and Agents Physiological Effects of Drugs Vasodilator Agents (...) remaining duration of the cluster cycle must be at least 3 weeks from Baseline Day 1 visit Able to differentiate other headache types from cluster headaches Is using or agrees to use a medically acceptable form of contraception(female of child-bearing potential) Negative urine pregnancy test prior to study entry(female of child-bearing potential) Concomitant medication that, in the opinion of the investigator and the patient's general practitioner(GP), do not pose an unacceptable risk based upon

2014 Clinical Trials

269. Efficacy, Safety, Tolerability and Pharmacokinetics of BIBN 4096 BS Versus Placebo in the Treatment of a Single Attack of Acute Migraine Headache

measured on four-point scale [ Time Frame: up to 24 hours post start of infusion ] Time to sustained Headache Response [ Time Frame: up to 24 hours post start of infusion ] Worsening/Recurrence of Headache pain [ Time Frame: 2 - 24 hours post start of infusion ] Tmax (Time to maximum concentration of the analyte in plasma) [ Time Frame: up to 4 hours post start of infusion ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important (...) 6 months History of treatment resistance migraine attacks defined as a lack of response to a range of commonly used acute anti-migraine compounds Females who are nursing or pregnant (as determined by a serum pregnancy test at screening and a urine pregnancy test at baseline) or of childbearing potential (any woman who is not at least 1 year post-menopausal or surgically sterile is considered to be of childbearing potential) and not using a medically approved method of birth control as defined

2014 Clinical Trials

270. Gabapentin for Headache in Aneurysmal Subarachnoid Hemorrhage

Study Description Go to Brief Summary: The purpose of this study is to see how much gabapentin will reduce headaches associated with subarachnoid hemorrhage (SAH) and to reduce the amount of narcotic pain medication prescribed. Condition or disease Intervention/treatment Phase Aneurysmal Subarachnoid Hemorrhage Drug: Gabapentin Drug: Placebo Phase 4 Detailed Description: We plan to use gabapentin (GBP), an FDA approved non-narcotic pain medication for neuropathic pain, which is also an alpha-2-delta (...) (placebo) arm. To accomplish this aim, we plan to randomize 20 aSAH patients with headache to either GBP and standard of care pain treatment versus placebo and standard of care treatment. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 14 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary Purpose: Treatment Official Title: Gabapentin

2014 Clinical Trials

271. Sphenopalatine Ganglion Stimulation for the Treatment of Chronic Cluster Headache

. Subject has been diagnosed with chronic cluster headache according to the 2013 ICHD, 3rd edition (beta version), criterion 3.1.2. Subject reports a minimum of 4 cluster attacks per week on the side of their dominant headache laterality. Subjects who report more than 8 attacks per day or attack duration of less than 30 minutes (untreated or unsuccessfully treated) must have been tested to rule out other forms of trigeminal autonomic cephalalgias. Both subject and physician judge previously or currently (...) who is pregnant, nursing, or not using contraception. Subject is currently participating or has participated in the last month in another clinical study in which the subject has, is, or will be exposed to an investigational or non-investigational drug or device. Subject has demonstrated or is believed to be at risk of non-compliance with study procedures (e.g., for completing the diary or maintaining a stable headache medicine regimen or returning for required follow-up visits). Subject is at risk

2014 Clinical Trials

272. Treatment of Chronic Post-Traumatic Headache With OnabotulinumtoxinA

: October 23, 2018 Sponsor: University of Washington Information provided by (Responsible Party): Sylvia Lucas, University of Washington Study Details Study Description Go to Brief Summary: This study will provide evidence on whether the use of an FDA-approved drug therapy for the treatment of chronic migraine (OnabotulinumtoxinA) shows similar efficacy for treatment of chronic headaches caused by traumatic injury to the brain (TBI) from a direct hit to the head, or a fall, or a motor vehicle accident (...) by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: Treatment with OnabotulinumtoxinA OnabotulinumtoxinA Drug: OnabotulinumtoxinA 155 units of OnabotulinumtoxinA administered intramuscularly. Injections are divided across seven injection specific head/neck muscle areas every 12 weeks to prevent chronic migraine post traumatic headache Other Name: BOTOX Outcome Measures Go to Primary Outcome Measures : Change in Mean

2014 Clinical Trials

273. Acetylsalicylic Acid (ASA) + Paracetamol + Caffeine Combination Compared With ASA + Paracetamol as Well as ASA, Paracetamol, and Caffeine in Headache Patients

, 3 and 4 hours after administration of the study medication ] Ratio of weighted sum of pain intensity difference scores to maximum achievable sum of pain intensity differences (%SPIDweighted), evaluated on a VAS [ Time Frame: Up to the end of the study ] Extent of impairment of daily activities, evaluated on a 4-grade verbal scale (VRS) [ Time Frame: Before, 30 min., 1, 2, 3 and 4 hours after administration of study drug ] Duration of headache [ Time Frame: Up to 48 hours after onset of each (...) inhibitors Concomitant treatments with anti-emetics Drug abuse connected with the headache (defined as the administration of analgesics or other drugs for the treatment of acute headache on more than 10 days per month) Alcohol or drug abuse as defined by diagnostic and statistical manual of mental disorders (DSM-IV) Pregnancy and lactation Gastrointestinal ulcers Pathologically increased bleeding tendency Glucose-6-phosphate dehydrogenase deficiency Hypersensitivity to paracetamol, caffeine, ASA

2014 Clinical Trials

274. Efficacy and Tolerability of Metamizol in Patients With Episodic Moderate Headache

: Boehringer Ingelheim ClinicalTrials.gov Identifier: Other Study ID Numbers: 1093.16 First Posted: July 8, 2014 Last Update Posted: July 8, 2014 Last Verified: July 2014 Additional relevant MeSH terms: Layout table for MeSH terms Headache Migraine Disorders Pain Neurologic Manifestations Signs and Symptoms Headache Disorders, Primary Headache Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Aspirin Dipyrone Anti-Inflammatory Agents, Non-Steroidal Analgesics, Non-Narcotic (...) Efficacy and Tolerability of Metamizol in Patients With Episodic Moderate Headache Efficacy and Tolerability of Metamizol in Patients With Episodic Moderate Headache - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2014 Clinical Trials

275. A Study of LY2951742 in Participants With Migraine Headache

. Required feature "A" includes at least 2 of the following headache characteristics: unilateral location, pulsatile quality, moderate or severe pain intensity, or aggravation by or causing avoidance of routine physical activity. Required feature "B" includes at least 1 of the following during the headache: nausea and/or vomiting, or photophobia and phonophobia. Secondary Outcome Measures : Mean Change From Baseline in Number of Migraine Attacks in the Last 28-Day Period of the 12-Week Treatment Phase (...) headache characteristics: unilateral location, pulsatile quality, moderate or severe pain intensity, or aggravation by or causing avoidance of routine physical activity. Required feature "B" includes at least 1 of the following during the headache: nausea and/or vomiting, or photophobia and phonophobia. Least Squares (LS) mean was calculated using mixed model repeated measures (MMRM) methodology with treatment, pooled investigative site, period, and treatment-by-period interaction, baseline

2014 Clinical Trials

276. Manual Therapy for Tension Headache With Psychological Disorders

of Valencia Study Details Study Description Go to Brief Summary: Introduction. Tension-type headache is a highly prevalent disorder with a significant socio-economic impact, affecting psychological aspects. This study aims to assess aspects pertaining to anxiety, depression, headache frequency and pain intensity. Subjects and methods. A clinical trial was conducted on 84 participants suffering from tension-type headache, divided into 4 groups, the mean age being 39.76 years (SD 11.38). The first group (...) conditions and their interaction on reported depression, anxiety, and headache pain frequency and intensity. Condition or disease Intervention/treatment Phase Tension-type Headache Other: The suboccipital technique Other: The articulatory technique Other: Combined treatment Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 84 participants Allocation: Randomized Intervention Model: Factorial Assignment Masking: Double

2014 Clinical Trials

277. Feasibility Study of Normobaric Oxygen Delivered by a High Flow Concentrator in the Treatment of Chronic Headache

treatment or same prophylaxis treatment from more than one month Signed informed consent Exclusion Criteria: Pregnancy One or more failed withdrawal treatment analgesic treatment for another reason than headache Contraindication of normobaric oxygen therapy Contraindication of ketoprofen (rescue therapy) Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information (...) provided by Caroline ROOS, Association pour la Recherche au Centre d'Urgence des Céphalées: withdrawal therapy oxygen therapy Additional relevant MeSH terms: Layout table for MeSH terms Headache Headache Disorders Pain Neurologic Manifestations Signs and Symptoms Brain Diseases Central Nervous System Diseases Nervous System Diseases

2014 Clinical Trials

278. Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

log on a minimum of 80% of recordable days Women of childbearing potential must not be pregnant, planning to become pregnant during the study period, or nursing. Participation in a headache support group or other activity such as meditation or yoga intended to mitigate headache or other chronic pain must be stable for at least 4 weeks prior to beginning the preliminary screening period and should be intended to be continued for the duration of the trial. Participants will be encouraged to defer (...) Office of Research and Development: controlled clinical trial randomized controlled clinical trial Additional relevant MeSH terms: Layout table for MeSH terms Brain Injuries Brain Injuries, Traumatic Headache Brain Concussion Post-Concussion Syndrome Combat Disorders Post-Traumatic Headache Brain Diseases Central Nervous System Diseases Nervous System Diseases Craniocerebral Trauma Trauma, Nervous System Wounds and Injuries Pain Neurologic Manifestations Signs and Symptoms Head Injuries, Closed

2014 Clinical Trials

279. Exercise in Migraine and Co-existing Tension-type Headache and Neck Pain

using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 65 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Migraine Tension-type headache Neck pain Exclusion Criteria: Whiplash injury or other significant neck trauma Nerve root compression Post traumatic headache Medication overuse headache Cluster headache Trigeminal neuralgia Pregnancy and breast (...) Exercise in Migraine and Co-existing Tension-type Headache and Neck Pain Exercise in Migraine and Co-existing Tension-type Headache and Neck Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Exercise

2014 Clinical Trials

280. Guideline Supplement: Trauma in pregnancy

trauma patients Intervention Provision of best practice trauma assessment and emergency care for pregnant women Comparison NIL Outcome Emergency care requirements specific to the pregnant trauma patient are identified Queensland Clinical Guideline Supplement: Trauma in pregnancy Refer to online version, destroy printed copies after use Page 4 of 11 2.3 Clinical questions The following clinical questions were generated to inform the guideline scope and purpose: • How do normal physiological/anatomical (...) changes of pregnancy affect management of the pregnant trauma patient? • What assessments are required for the pregnant trauma patient beyond that required for the non-pregnant trauma patient? • What are common obstetric complications in the pregnant trauma patient and how should they be managed? • What care is indicated for pregnant woman following minor trauma? 2.4 Exclusions The following exclusions were identified in the guideline scope: 1. Standard/usual care that also applies to the non-pregnant

2014 Queensland Health

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