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Headache in Pregnancy

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201. A Prospective Observational Registry of Primary Headache Patients Treated With Ausanil

: VR1 Corporation Information provided by (Responsible Party): VR1 Corporation Study Details Study Description Go to Brief Summary: This study is an observational study with the primary objective to assess the safety and tolerability of Ausanil in the treatment of primary headache disorders. The secondary objective is to assess headache pain, functional outcome, time loss to headache and patient satisfaction with Ausanil treatment. Condition or disease Intervention/treatment Primary Headache (...) provided by VR1 Corporation: migraine cluster headache primary headache Ausanil capsicum annuum Additional relevant MeSH terms: Layout table for MeSH terms Headache Headache Disorders Headache Disorders, Primary Pain Neurologic Manifestations Signs and Symptoms Brain Diseases Central Nervous System Diseases Nervous System Diseases

2015 Clinical Trials

202. Auditory function following post-dural puncture headache treated with epidural blood patch. A long-term follow-up. (Abstract)

Auditory function following post-dural puncture headache treated with epidural blood patch. A long-term follow-up. Epidural analgesia is commonly used for pain management during labor. Sometimes, accidental dural puncture (ADP) occurs causing severely debilitating headache, which may be associated with transient hearing loss. We investigated if auditory function may be impaired several years after ADP treated with epidural blood patch (EBP).Sixty women (ADP group) without documented hearing (...) disability, who received EBP following ADP during labor between the years 2005-2011 were investigated in 2013 for auditory function using the following tests: otoscopic examination, tympanometry, pure tone audiometry, and transient-evoked otoacoustic emissions. Additionally, they responded to a questionnaire, the Speech, Spatial and Qualities (SSQ) of hearing, concerning perceived hearing impairment. The results were compared to a control group of 20 healthy, non-pregnant women in the same age group.The

2015 Acta Anaesthesiologica Scandinavica

203. Effectiveness of Manual Treatment on Pregnancy Symptoms: Usefulness of Manual Treatment in Treating Pregnancy Symptoms Full Text available with Trip Pro

was unsuccessful underwent second round of treatment after a pause of a minimum 3 days. Patients for whom the treatment was initially successful but later relapsed also repeated whole procedure. Pregnancy symptoms analyzed in this study were heartburn, nausea, vomiting, dizziness, headache, insomnia, neck pain, hyperosmia and hypersalivating.Manual treatment successfully treated pregnancy symptoms in 91 (79.1%) patients, it was partially successful for 22 (19.1%), and unsuccessful for 2 patients (1.7%) after (...) the first treatment. After the second treatment, out of a total 56 patients, the treatment was completely successful in 40 (71.4%), partially successful in 14 (25%), and unsuccessful in 2 (3.6%) patients. The highest success rate was in eliminating headache (97.3%), vomiting (95.9%), dizziness (94.5%), nausea (92.9%), neck pain (92.9%), insomnia (91.9%), heartburn (88.8%), hyperosmia (78.5%) and hyper salivating (78%).Manual therapy in pregnancy is a drugless, etiological, usually highly effective

2018 Medical Archives

204. Polycystic ovary syndrome: metformin in women not planning pregnancy

. Metformin use is associated with gastrointestinal adverse effects (nausea, vomiting and diarrhoea), which can be severe. The Cochrane review found that metformin caused a significantly higher incidence of gastrointestinal adverse effects that were severe (leading to treatment discontinuation) compared with co-cyprindiol, and a significantly lower incidence of other severe adverse effects (weight gain, high blood pressure, depression, chest pain and headache). Among all 9 trials there was significant (...) , cardiovascular events or endometrial cancer in women with PCOS. Gastrointestinal adverse effects, which occasionally caused women to stop treatment, were more commonly reported with metformin than co-cyprindiol. Other adverse effects that caused women to stop treatment (weight gain, high blood pressure, depression, chest pain and headache) were more commonly reported with co-cyprindiol than metformin. Summary of the evidence This section gives a brief summary of the main evidence. A more thorough analysis

2013 National Institute for Health and Clinical Excellence - Advice

205. Chickenpox in Pregnancy

or postpartum is an option that should be considered for women who are found to be seronegative for varicella-zoster virus immunoglobulin G (VZV IgG). While universal serological antenatal testing is not recommended in the UK (see below), seronegative women identified in pregnancy could be offered postpartum immunisation. Women who are vaccinated postpartum can be reassured that it is safe to breastfeed. Can varicella be prevented in the pregnant woman at her initial antenatal visit? Women booking (...) for antenatal care should be asked about previous chickenpox/shingles infection. Women who have not had chickenpox, or are known to be seronegative for chickenpox, should be advised to avoid contact with chickenpox and shingles during pregnancy and to inform healthcare workers of a potential exposure without delay. Can varicella infection be prevented in the pregnant woman who gives a history of contact with chickenpox or shingles? When contact occurs with chickenpox or shingles, a careful history must

2015 Royal College of Obstetricians and Gynaecologists

206. The Acute Management of Thrombosis and Embolism during Pregnancy and the Puerperium

) or with other complicating factors (for example, with renal impairment or recurrent VTE). Routine platelet count monitoring should not be carried out. Obstetric patients who are postoperative and receiving unfractionated heparin should have platelet count monitoring performed every 2–3 days from days 4 to 14 or until heparin is stopped. [New 2015] How should massive life-threatening PE in pregnancy and the puerperium be managed? Collapsed, shocked women who are pregnant or in the puerperium should (...) disposal of needles and syringes. Outpatient follow-up should include clinical assessment and advice with monitoring of blood platelets and peak anti-Xa levels if appropriate (see sections 5 and 6.3). Pregnant women who develop heparin-induced thrombocytopenia or have heparin allergy and require continuing anticoagulant therapy should be managed with an alternative anticoagulant under specialist advice. Can vitamin K antagonists be used during pregnancy for the maintenance treatment of VTE? Because

2015 Royal College of Obstetricians and Gynaecologists

207. Reducing the Risk - Thrombosis and Embolism during Pregnancy and the Puerperium

with previous VTE be managed in pregnancy? (see Appendix IV) Single previous VTE Women with previous VTE should be offered prepregnancy counselling and a prospective management plan for thromboprophylaxis in pregnancy made. Those who become pregnant before receiving such counselling should be referred at the earliest opportunity in pregnancy to a clinician with expertise in thrombosis in pregnancy. C C C D D D D P PRCOG Green-top Guideline No. 37a © Royal College of Obstetricians and Gynaecologists 3 of 40 (...) be avoided antenatally and intrapartum because of the risk of anaphylactoid reaction. Oral thrombin and Xa inhibitors Non-vitamin K antagonist oral anticoagulants (NOACs) should be avoided in pregnant women. [New 2015] Use of NOACs is not currently recommended in women who are breastfeeding. [New 2015] Anti-embolism stockings The use of properly applied anti-embolism stockings (AES) of appropriate size and providing graduated compression with a calf pressure of 14–15 mmHg is recommended in pregnancy

2015 Royal College of Obstetricians and Gynaecologists

208. Itch in pregnancy: Chlorphenamine

— dizziness, restlessness, tinnitus, psychomotor impairment, headaches, sedation that can persist for up to 12 hours (affected people should not drive or operate heavy machinery), muscle twitching. Anticholinergic effects — blurred vision, dry mouth, and urinary retention. Skin — urticaria, rash, exfoliative dermatitis, photosensitivity. Gastrointestinal — nausea, vomiting, abdominal pain, diarrhoea, dyspepsia, anorexia, hepatitis. Cardiovascular — palpitations, tachycardia, arrhythmias, hypotension (...) Itch in pregnancy: Chlorphenamine Chlorphenamine | Prescribing information | Itch in pregnancy | CKS | NICE Search CKS… Menu Chlorphenamine Itch in pregnancy: Chlorphenamine Last revised in April 2020 Chlorphenamine Contraindications and cautions Chlorphenamine is not contraindicated in pregnancy (but is not specifically licensed for use in pregnancy). Use around the time of delivery may cause irritability, paradoxical excitability, and tremor in the neonate. Chlorphenamine should be used

2019 NICE Clinical Knowledge Summaries

209. Antenatal care - uncomplicated pregnancy: Scenario: Managing common minor ailments

of the available scientific evidence carried out by the UK Teratology Information Service (UKTIS) [ ; ]. Vaginal discharge Advise the woman that an increase in vaginal discharge is normal during pregnancy. If the discharge is associated with itch, soreness, offensive smell, or pain on passing urine, investigate for an underlying cause, such as bacterial vaginosis, vaginal candidiasis, or trichomoniasis, and manage as appropriate. For more information, see the CKS topics on , , , and . The UK Teratology (...) on expert opinion in the National Institute of Health and Care Excellence (NICE) guideline Antenatal Care for Uncomplicated Pregnancies [ ]. Further information is derived from a Department of Health (DoH) publication The Pregnancy Book [ ]. Backache Advise the women that exercising in water, massage therapy, and group or individual back care classes might help to ease back pain during pregnancy. Paracetamol is generally considered to be safe to use in pregnancy. The UK Teratology Information Service

2019 NICE Clinical Knowledge Summaries

210. COVID-19 in Children, Pregnancy and Neonates: A Review of Epidemiologic and Clinical Features. Full Text available with Trip Pro

COVID-19 in Children, Pregnancy and Neonates: A Review of Epidemiologic and Clinical Features. The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has spread rapidly across the globe. In contrast to initial reports, recent studies suggest that children are just as likely as adults to become infected with the virus but have fewer symptoms and less severe disease. In this review, we summarize the epidemiologic and clinical features of children infected with SARS-CoV-2 (...) reported in pediatric case series to date. We also summarize the perinatal outcomes of neonates born to women infected with SARS-CoV-2 in pregnancy. We found 11 case series including a total of 333 infants and children. Overall, 83% of the children had a positive contact history, mostly with family members. The incubation period varied between 2 and 25 days with a mean of 7 days. The virus could be isolated from nasopharyngeal secretions for up to 22 days and from stool for more than 30 days. Co

2020 Pediatric Infectious Dsease Journal

211. Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know. Full Text available with Trip Pro

. For severe acute respiratory syndrome, the largest series of 12 pregnancies had a case-fatality rate of 25%. Complications included acute respiratory distress syndrome in 4, disseminated intravascular coagulopathy in 3, renal failure in 3, secondary bacterial pneumonia in 2, and sepsis in 2 patients. Mechanical ventilation was 3 times more likely among pregnant compared with nonpregnant women. Among 7 first-trimester infections, 4 ended in spontaneous abortion. Four of 5 women with severe acute (...) respiratory syndrome after 24 weeks' gestation delivered preterm. For Middle East respiratory syndrome, there were 13 case reports in pregnant women, of which 2 were asymptomatic, identified as part of a contact investigation; 3 patients (23%) died. Two pregnancies ended in fetal demise and 2 were born preterm. No evidence of in utero transmission was seen in severe acute respiratory syndrome or Middle East respiratory syndrome. Currently no coronavirus-specific treatments have been approved by the US

2020 American Journal of Obstetrics and Gynecology

212. Elevated Blood Lead Levels in Children and Pregnant Women: Screening

, and financial costs associated with return visits and repeated tests. Children with significantly elevated blood lead levels might receive chelation therapy, which is associated with a wide range of harms, including injection site pain or abscess, headache, paresthesia, tremors, rash, neutropenia, elevation of serum liver transaminase, hypertension, tachycardia, fever, nausea, vomiting, or other gastrointestinal upset. Current Practice There are no data on the proportion of clinicians who screen (...) systems, including the cardiovascular, renal, and hepatic systems, with most symptoms occurring at blood lead levels of 50 μg/dL or greater. Very high levels of inorganic lead exposure may result in death or long-term neurologic symptoms in children. However, behavioral disorders are associated with blood lead levels as low as 5 μg/dL in young children. Adverse effects of very high maternal blood lead levels during pregnancy include abortion, stillbirth, preterm delivery, decreased neonatal head

2019 U.S. Preventive Services Task Force

213. What are the recommended clinical assessment and screening tests during pregnancy?

but also deleterious effects on pregnant women such as overdiagnosis, overtreatment, and related anxiety. 1.2. Remit of the guideline The main objectives pursued by this guideline are to offer information on best practices for baseline clinical care of all pregnancies and comprehensive information for the follow-up of the low-risk pregnant women. The scope of this guideline was defined in collaboration with the guideline development group (GDG) members and stakeholders which decided to focus on low (...) information on the additional care that some women will require due to specific risk factors or pre-existing conditions. Although the guideline addresses screening for many of the complications of pregnancy, it does not include information on the investigation and appropriate management of these complications (for example, the management of pre-eclampsia, fetal anomalies and multiple pregnancies). In addition, this guideline does not provide advices about general lifestyle and nutrition of pregnant women

2015 Belgian Health Care Knowledge Centre

214. Itch in pregnancy: Promethazine

— promethazine may thicken or dry lung secretions and impair expectoration. [ ; ] Adverse effects Adverse effects of promethazine include: Neurological — dizziness, restlessness, headaches, nightmares, sedation that can persist for up to 12 hours (affected people should not drive or operate heavy machinery), muscle spasms and tic-like movements of the head and face, extrapyramidal effects. Anticholinergic effects — blurred vision, dry mouth, urinary retention. Skin — urticaria, rash, pruritus (...) Itch in pregnancy: Promethazine Promethazine | Prescribing information | Itch in pregnancy | CKS | NICE Search CKS… Menu Promethazine Itch in pregnancy: Promethazine Last revised in April 2020 Promethazine Contraindications and cautions Promethazine is not contraindicated in pregnancy (but is not specifically licensed for use in pregnancy). Use around the time of delivery may cause irritability, paradoxical excitability, and tremor in the neonate. Promethazine should not be used in people

2018 NICE Clinical Knowledge Summaries

215. Guideline supplement: Hypertensive disorders of pregnancy

worsening of the disorder and the necessity to contact their care provider when experiencing symptoms (severe headache, pain upper right abdominal or epigastric pain, hyperreflexia, vision disorders and convulsions) Section 3.3 Queensland Clinical Guideline Supplement: Hypertensive disorders of pregnancy Refer to online version, destroy printed copies after use Page 11 of 13 4.5 Safety and quality Implementation of this guideline provides evidence of compliance with the NSQHS and Australian Council (...) Guideline supplement: Hypertensive disorders of pregnancy Maternity and Neonatal C linical G uideline Queensland Health Supplement: Hypertensive disorders of pregnancy Queensland Clinical Guideline Supplement: Hypertensive disorders of pregnancy Refer to online version, destroy printed copies after use Page 2 of 13 Table of Contents 1 Introduction 3 1.1 Funding 3 1.2 Conflict of interest 3 1.3 Guideline review 3 2 Methodology 4 2.1 Topic identification 4 2.2 Scope 4 2.3 Clinical questions 4 2.4

2016 Queensland Health

216. Hypertensive disorders of pregnancy

for all women 13 Advice if high risk of preeclampsia • Advise women at high risk of hypertensive disorders of pregnancy (HDP) of the symptoms of preeclampsia and to seek immediate advice from a health care professional if symptoms present. • Symptoms include 13 : o Severe headache o Problems with vision (e.g. blurring or flashing before the eyes) o Severe pain just below the ribs on the right side o Vomiting o Sudden swelling of the face, hands or feet Therapies unsupported by evidence (...) IV rapid bolus Onset: 3–5 minutes Repeat: after 5 minutes Maximum 150 mg/dose Monitor Blood Glucose Levels Note: *Refer to the Queensland Health List of Approved Medicines (LAM) for prescribing restrictions # Special Access Scheme (SAS) authority required Queensland Clinical Guideline: Hypertensive disorders of pregnancy Refer to online version, destroy printed copies after use Page 14 of 32 5 Preeclampsia Severe hypertension, headache, epigastric pain, oliguria or nausea and vomiting are ominous

2016 Queensland Health

217. IBD: Pregnancy

containing dibutyl phthalate (DBP), we suggest switching to a 5-ASA drug without DBP. GRADE: Conditional recommendation, very low-quality evidence. Statement4A. In womenwithIBDwho aretakingmethotrexateandcontemplating pregnancy, werecommend stoppingmethotrexateat least 3monthsbeforeattemptingtoconceivetominimizetheriskofteratogenicity.GRADE:Strongrecommendation,verylow-qualityevidence. Statement 4B. If a woman becomes pregnant while taking methotrexate, we recommend immediate discontinuation (...) of methotrexate and referral for obstetric counseling. GRADE: Strong recommendation, very low-quality evidence. Statement 5. In pregnant women with active or complicated IBD, we recommend consultation with an obstetrician, preferably one af?liated with a high-risk obstetrics program. GRADE: Strong recommendation, very low-quality evidence. Statement 6. In pregnant women with IBD, we recommend their IBD be managed by a gastroenterologist throughout pregnancy. GRADE: Strong recommendation, very low-quality

2016 Canadian Association of Gastroenterology

218. WHO recommendations on antenatal care for a positive pregnancy experience

WHO recommendations on antenatal care for a positive pregnancy experience WHO recommendations on antenatal care for a positive pregnancy experienceWHO Library Cataloguing-in-Publication Data WHO recommendations on antenatal care for a positive pregnancy experience. I.World Health Organization. ISBN 978 92 4 154991 2 Subject headings are available from WHO institutional repository © World Health Organization 2016 All rights reserved. Publications of the World Health Organization are available (...) Health Organization (WHO) envisions a world where every pregnant woman and newborn receives quality care throughout the pregnancy, childbirth and the postnatal period. Within the continuum of reproductive health care, antenatal care (ANC) provides a platform for important health-care functions, including health promotion, screening and diagnosis, and disease prevention. It has been established that by implementing timely and appropriate evidence-based practices, ANC can save lives. Crucially, ANC

2016 World Health Organisation Guidelines

219. Assessment and Treatment of Pregnant Women With Suspected or Confirmed Influenza

on a variety of symptoms, including but not limited to fever of 100.4 ◦ F or higher, cough, fatigue, headache, and body aches. It is important to note that not all people infected with influenza will develop a fever; therefore, the absence of fever should not rule out an influenza diagnosis (see Fig. 1). Initial triage and treatment by telephone is acceptable to help reduce the spread of disease among other pregnant patients in the office. Following symptom assessment, obstetrician–gynecologists and other (...) influenza infection. Pregnancy itself is a high-risk condition, making the potential adverse effects of influenza particularly serious in pregnant women. If a pregnant woman has other underlying health conditions, the risk of adverse effects from influenza is even greater. Antiviral treatment is necessary for all pregnant women with suspected or confirmed influenza, regardless of vaccination status. Obstetrician–gynecologists and other obstetric care providers should promptly recognize the symptoms

2018 American College of Obstetricians and Gynecologists

220. Syphilis Infection in Pregnant Women: Screening

but individualize decision making to the specific patient or situation. Similarly, the USPSTF notes that policy and coverage decisions involve considerations in addition to the evidence of clinical benefits and harms. Importance Syphilis is an infection that is primarily sexually transmitted. Untreated syphilis infection in pregnant women can also be transmitted to the fetus (congenital syphilis) at any time during pregnancy or at birth. Congenital syphilis is associated with stillbirth, neonatal death (...) The USPSTF found adequate evidence that screening tests can accurately detect syphilis infection in pregnant women. Benefits of Detection and Early Treatment The USPSTF found convincing evidence that early universal screening for syphilis infection in pregnant women reduces the incidence of congenital syphilis and the adverse outcomes of pregnancy associated with maternal infection. Harms of Detection and Early Treatment Screening for syphilis infection in pregnant women may result in potential harms

2018 U.S. Preventive Services Task Force

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