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Hamilton Anxiety Scale

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1. Psychometric Properties of the Reconstructed Hamilton Depression and Anxiety Scales (PubMed)

Psychometric Properties of the Reconstructed Hamilton Depression and Anxiety Scales Although widely used, the Hamilton Rating Scale for Depression (HRSD) and Hamilton Anxiety Rating Scale (HARS) discriminate poorly between depression and anxiety. To address this problem, Riskind, Beck, Brown, and Steer (J Nerv Ment Dis. 175:474-479, 1987) created the Reconstructed Hamilton Scales by reconfiguring HRSD and HARS items into modified scales. To further analyze the reconstructed scales, we examined (...) their factor structure and criterion-related validity in a sample of patients with major depressive disorder and no comorbid anxiety disorders (n = 215) or with panic disorder and no comorbid mood disorders (n = 149). Factor analysis results were largely consistent with those of Riskind et al. The correlation between the new reconstructed scales was small. Compared with the original scales, the new reconstructed scales correlated more strongly with diagnosis in the expected direction. The findings

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2017 The Journal of nervous and mental disease

2. Hamilton Anxiety Scale

Hamilton Anxiety Scale Hamilton Anxiety Scale Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Hamilton Anxiety Scale Hamilton Anxiety (...) Scale Aka: Hamilton Anxiety Scale , HAM-A II. Background Authored by Max Hamilton in 1959 Public domain anxiety rating scale III. Criteria: Symptom Rating Scale (0=Not Present, 4=Disabling) Anxious Mood Worries Anticipates worst Tension Startles Cries easily Restless Trembling Fears Fear of the dark Fear of strangers Fear of being alone Fear of animal Difficulty falling asleep or staying asleep Difficulty with s Intellectual Poor concentration Memory Depressed Mood Decreased interest in activities

2018 FP Notebook

3. The Major Depressive Disorder Hierarchy: Rasch Analysis of 6 items of the Hamilton Depression Scale Covering the Continuum of Depressive Syndrome. (PubMed)

The Major Depressive Disorder Hierarchy: Rasch Analysis of 6 items of the Hamilton Depression Scale Covering the Continuum of Depressive Syndrome. Melancholic features of depression (MFD) seem to be a unidimensional group of signs and symptoms. However, little importance has been given to the evaluation of what features are related to a more severe disorder. That is, what are the MFD that appear only in the most depressed patients. We aim to demonstrate how each MFD is related to the severity (...) of the major depressive disorder.We evaluated both the Hamilton depression rating scale (HDRS-17) and its 6-item melancholic subscale (HAM-D6) in 291 depressed inpatients using Rasch analysis, which computes the severity of each MFD. Overall measures of model fit were mean (±SD) of items and persons residual = 0 (±1); low χ2 value; p>0.01.For the HDRS-17 model fit, mean (±SD) of item residuals = 0.35 (±1.4); mean (±SD) of person residuals = -0.15 (±1.09); χ2 = 309.74; p<0.00001. For the HAM-D6 model fit

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2017 PLoS ONE

4. Hamilton Depression Scale

Depression Scale Aka: Hamilton Depression Scale , Ham-D II. Background Twenty one question Survey completed by physician III. Questions Depressed mood (0 to 4) Feelings of guilt (0 to 4) (0 to 4) Early (0 to 2) Middle (0 to 2) Late (0 to 2) Work activities (0 to 4) Retardation to stupor (0 to 4) (0 to 2) Fear (0 to 4) Anxiety (0 to 4) Gastrointestinal symptoms (0 to 2) Systemic somatic symptoms (0 to 2) Decreased libido or menstrual disturbance (0 to 2) (0 to 4) Weight loss (0 to 2) Diminished insight (0 (...) Hamilton Depression Scale Hamilton Depression Scale Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Hamilton Depression Scale Hamilton

2018 FP Notebook

5. The efficacy of paroxetine and placebo in treating anxiety and depression: a meta-analysis of change on the hamilton rating scales. (PubMed)

The efficacy of paroxetine and placebo in treating anxiety and depression: a meta-analysis of change on the hamilton rating scales. Previous meta-analyses of published and unpublished trials indicate that antidepressants provide modest benefits compared to placebo in the treatment of depression; some have argued that these benefits are not clinically significant. However, these meta-analyses were based only on trials submitted for the initial FDA approval of the medication and were limited (...) examined the data from all placebo-controlled, double-blind trials of paroxetine that included change scores on the Hamilton Rating Scale for Anxiety (HRSA) and/or the Hamilton Rating Scale for Depression (HRSD). For the treatment of anxiety (k = 12), the efficacy difference between paroxetine and placebo was modest (d = 0.27), and independent of baseline severity of anxiety. Overall change in placebo-treated individuals replicated 79% of the magnitude of paroxetine response. Efficacy was superior

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2014 PloS one

6. Anxiety rating scales in Parkinson's disease: A validation study of the Hamilton anxiety rating scale, the Beck anxiety inventory, and the hospital anxiety and depression scale. (PubMed)

Anxiety rating scales in Parkinson's disease: A validation study of the Hamilton anxiety rating scale, the Beck anxiety inventory, and the hospital anxiety and depression scale. Anxiety is a prevalent and disabling condition in Parkinson's disease (PD). The lack of anxiety rating scales validated for this population hampers research into anxiety in PD. The aim of this study is to assess the clinimetric properties of the Hamilton anxiety rating scale (HARS), the Beck anxiety inventory (BAI (...) ), and the hospital anxiety and depression scale (HADS) in PD patients.Three hundred forty-two PD patients underwent a standardized assessment including a structured interview for diagnostic and statistical manual diagnoses of anxiety disorders and completion of the HARS, BAI, and HADS. Inter-rater reliability of the HARS was assessed in 60 patients; test-retest reliability of the BAI and HADS in 213 and 217 patients, respectively.Thirty-four percent of patients suffered from an anxiety disorder, whereas

2011 Movement Disorders

7. Alpha-Stim AID for anxiety

, cranial electrotherapy stimulation; FDADS, four-dimensional anxiety and depression scale-anxiety subscale; GAD, generalised anxiety disorder; HAM-A, Hamilton Anxiety Rating Scale; HAM-D, Hamilton Depression Rating Scale; SAS, self-rating anxiety; SDS, self-rating depression; SD, standard deviation. Recent and ongoing studies CES in the treatment of post-traumatic stress disorder. ClinicalTrial.gov identifier: NCT 03757494. Status: recruiting. Indication: post-traumatic stress disorder. Intervention (...) . Intervention and comparator(s) Alpha-Stim SCS. No comparator. Key outcomes Mean HAM-A score decreased significantly from 21.25 (SD=5.82) at baseline to 12.67 (SD=5.47) the end of the study (6 weeks, p=0.01). Six patients (50%) had a 50% decrease on HAM-A and a score of 1 or 2 on the Clinical Global Impression – Improvement scale and GAD was considered to respond to treatment. The FDADS-anxiety subscale score reduced significantly from 30.58 (SD=11.24) at baseline to 23.83 (SD=7.57) at the end of the study

2019 National Institute for Health and Clinical Excellence - Advice

8. Worsening Anxiety, Irritability, Insomnia, or Panic Predicts Poorer Antidepressant Treatment Outcomes: Clinical Utility and Validation of the Concise Associated Symptom Tracking (CAST) Scale (PubMed)

and overall worsening with remission was tested with logistic regression analyses.The 5-domain structure had adequate model fit on confirmatory factor analysis (GFI=0.93, CFI=0.89, and RMSEA=0.07). Scores on anxiety, panic, insomnia, and mania significantly correlated with Hamilton Rating Scale for Depression anxiety subscale (rs=0.27), Psychiatric Diagnostic Screening Questionnaire-panic scale (rs=0.35), sum of 3 Quick Inventory of Depressive Symptomatology Self-Report insomnia items (rs=0.55 (...) Worsening Anxiety, Irritability, Insomnia, or Panic Predicts Poorer Antidepressant Treatment Outcomes: Clinical Utility and Validation of the Concise Associated Symptom Tracking (CAST) Scale We report on the psychometric properties of the 16-item Concise Associated Symptom Tracking Scale self-report scale and its clinical utility.The 5-domain (irritability, anxiety, mania, insomnia, and panic) structure of Concise Associated Symptom Tracking Scale was validated with confirmatory factor analysis

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2017 International Journal of Neuropsychopharmacology

9. Systematic Review - Relationship of Deployment-related Mild Traumatic Brain Injury to Posttraumatic Stress Disorder, Depressive Disorders, Substance Use Disorders, Suicidal Ideation, and Anxiety Disorders

Depression CPT Cognitive Processing Therapy CTBIE Comprehensive Traumatic Brain Injury Evaluation DoD Department of Defense DSM-IV Diagnostic and Statistical Manual of Mental Disorders, 4 th edition DVBIC Defense and Veterans Brain Injury Center ES Effect size HAM-A Hamilton Anxiety Rating Scale HBO2 Hyperbaric Oxygen Therapy HSR&D Health Services Research & Development ICD International Classification of Diseases ISS Injury Severity Score LOC Loss of consciousness MADRS Montgomery-Asberg Depression (...) Acceptance and Commitment Therapy AIS Abbreviated Injury Scale AOC Alteration of consciousness AS Altered state AUDIT-(C) Alcohol Use Disorders Identification Test-(Consumption) BAI Beck Anxiety Inventory BDI Beck Depression Inventory BHM Behavioral Health Measure BSI Brief Symptom Inventory CAGE Cutting down, Annoyance by criticism, Guilty feeling, and Eye openers CAPS (CAPS- IV) Clinician Administered PTSD Scale (CAPS for DSM-IV) CCT Controlled clinical trial CESD Center for Epidemiologic Studies

2019 Veterans Affairs Evidence-based Synthesis Program Reports

10. Hamilton Anxiety Scale

Hamilton Anxiety Scale Hamilton Anxiety Scale Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Hamilton Anxiety Scale Hamilton Anxiety (...) Scale Aka: Hamilton Anxiety Scale , HAM-A II. Background Authored by Max Hamilton in 1959 Public domain anxiety rating scale III. Criteria: Symptom Rating Scale (0=Not Present, 4=Disabling) Anxious Mood Worries Anticipates worst Tension Startles Cries easily Restless Trembling Fears Fear of the dark Fear of strangers Fear of being alone Fear of animal Difficulty falling asleep or staying asleep Difficulty with s Intellectual Poor concentration Memory Depressed Mood Decreased interest in activities

2015 FP Notebook

11. Interventions for treating anxiety after stroke. (PubMed)

= 0.926, P value = 0.001; 19 participants analysed).The second trial randomised 81 participants with co-morbid anxiety and depression to paroxetine, paroxetine plus psychotherapy, or standard care. Mean levels of anxiety severity scores based on the Hamilton Anxiety Scale (HAM-A) at follow-up were 5.4 (SD ± 1.7), 3.8 (SD ± 1.8), and 12.8 (SD ± 1.9), respectively (P value < 0.01).The third trial randomised 94 stroke patients, also with co-morbid anxiety and depression, to receive buspirone (...) included three trials (four interventions) involving 196 participants with stroke and co-morbid anxiety. One trial (described as a 'pilot study') randomised 21 community-dwelling stroke survivors to four-week use of a relaxation CD or to wait list control. This trial assessed anxiety using the Hospital Anxiety and Depression Scale and reported a reduction in anxiety at three months among participants who had used the relaxation CD (mean (standard deviation (SD) 6.9 (± 4.9) and 11.0 (± 3.9)), Cohen's d

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2017 Cochrane

12. The Parkinson Anxiety Scale (PAS): Development and validation of a new anxiety scale. (PubMed)

analysis and a Rasch analysis of items of the Hamilton Anxiety Rating Scale (HARS) and the Beck Anxiety Inventory (BAI) from a previously published study. Validation was done in a cross-sectional international multicenter study involving 362 patients with idiopathic PD. Patients underwent a single screening session in which the PAS was administered, along with the Hamilton Depression Rating Scale, the HARS, and the BAI. The Mini International Neuropsychiatric Interview was administered to establish (...) The Parkinson Anxiety Scale (PAS): Development and validation of a new anxiety scale. Existing anxiety rating scales have limited construct validity in patients with Parkinson's disease (PD). This study was undertaken to develop and validate a new anxiety rating scale, the Parkinson Anxiety Scale (PAS), that would overcome the limitations of existing scales. The general structure of the PAS was based on the outcome of a Delphi procedure. Item selection was based on a canonical correlation

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2014 Movement Disorders

13. Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis. (PubMed)

on randomised trials in adult outpatients with generalised anxiety disorder identified from MEDLINE, Web of Science, Cochrane Library, ClinicalTrials.gov, Chinese National Knowledge Infrastructure (CNKI), Wanfang data, Drugs@FDA and commercial pharmaceutical registries. Placebo and active control trials were included. Data were extracted from all manuscripts and reports. Primary outcomes were efficacy (mean difference [MD] in change in Hamilton Anxiety Scale Score) and acceptability (study discontinuations (...) Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis. Generalised anxiety disorder is a disease that can be associated with substantial dysfunction. Pharmacological treatment is often the first choice for clinicians because of the cost and resource constraints of psychological alternatives, but there is a paucity of comparative information for the multiple available drug choices.A systematic review and network meta-analysis was performed

2019 Lancet

14. Do some anxiety disorders belong to the prodrome of bipolar disorder? A clinical study combining retrospective and prospective methods to analyse the relationship between anxiety disorder and bipolar disorder from the perspective of biorhythms. (PubMed)

of reduction in scores on the Hamilton Anxiety Scale and Yale-Brown Obsessive Compulsive Scale, and the changes in Clinical Global Impression scores at different follow-up times: the anxiety group and the atypical BD group (who used mood stabilizers to treat AD). All subjects also completed the NEO Five-Factor Inventory and supplied blood samples to be tested for several endocrine indices (TSH, T3, FT3, T4, FT4, ACTH,PTC) and inflammatory cytokines (IL-6, IL-8, IL-10, TNF-α, CRP) at enrolment.In total, 14 (...) Do some anxiety disorders belong to the prodrome of bipolar disorder? A clinical study combining retrospective and prospective methods to analyse the relationship between anxiety disorder and bipolar disorder from the perspective of biorhythms. In clinical practice, some patients diagnosed with anxiety disorder (AD) may develop bipolar disorder (BD) many years later, and some cases of AD may be cured by the use of mood stabilizers. However, the relationship between AD and BD should be explored

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2017 BMC Psychiatry

15. Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers

: Anxiety sub-scale of the Hospital Anxiety and Depression Scale [ Time Frame: Baseline (1-2 weeks after enrollment) and Follow-up (7-9 weeks after baseline) ] Change in anxiety from baseline to follow-up Hamilton Anxiety Rating Scale [ Time Frame: Baseline (1-2 weeks after enrollment) and Follow-up (7-9 weeks after baseline) ] Change in anxiety from baseline to follow-up Secondary Outcome Measures : Depression sub-scale of the Hospital Anxiety and Depression Scale [ Time Frame: Baseline (1-2 weeks (...) of the patient-caregiver dyad, at least one member reports elevated anxiety as defined by a score of 8 or greater on the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS) As per self-report, residency in New York or ability to complete sessions in New York Able to communicate over the phone for sessions Willingness to be audio-recorded for assessments and, if applicable, study sessions CAREGIVERS: Age 21 or older As determined by the patient‟s primary oncologist and/or study staff

2017 Clinical Trials

16. LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders

-IV or a state-trait anxiety inventory score >40 in the STAI trait or state scale) with or without life-threatening illness. Main outcome measures: Reduction in anxiety (STAI), depression (Hamilton depression rating scale, HDRS and Beck depression inventory, BDI), and general psychopathological symptoms (Symptom Check List 90 items, SCL-90) at 2, 8, and 16 weeks after LSD- compared with placebo-assisted psychotherapy. Significance: Anxiety disorder (alone or in the context of life-threatening (...) )-IV or have a score of at least 40 on the state- or trait STAI scale at study inclusion. 40% or more of the participants should have a diagnosis of advanced-stage potentially fatal illness (autoimmune, neurological, or cancer without central nervous system (CNS) involvement). Patients should be ambulatory and not terminal and likely to have a roughly estimated life expectancy of > twelve months. Patients without advanced-stage potentially fatal illness need to meet DSM-IV criteria for anxiety

2017 Clinical Trials

17. On the Differential Diagnosis of Anxious from Nonanxious Major Depression by means of the Hamilton Scales (PubMed)

On the Differential Diagnosis of Anxious from Nonanxious Major Depression by means of the Hamilton Scales Anxious major depressive disorder (A-MDD) is differentially diagnosed from nonanxious MDD (NA-MDD) as MDD with a cut-off score ≥ 7 on the HAM-D anxiety-somatization factor (ASF). We investigated whether additional HAM-D items discriminate A-MDD from NA-MDD. Moreover, we tested the validity of ASF criterion against HAM-A, gold standard of anxiety severity assessment.164 consecutive female (...) middle-aged inpatients, diagnosed as A-MDD (n = 92) or NA-MDD (n = 72) by the normative HAM-A score for moderate-to-severe anxiety (≥ 25), were compared regarding 17-item HAM-D scores. The validity of ASF ≥ 7 criterion was assessed by receiver-operating characteristics (ROC) analysis.We found medium and large effect size differences between A-MDD and NA-MDD patients in only four out of the six ASF items, as well as in three further HAM-D items, namely, those of agitation, middle insomnia, and delayed

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2013 The Scientific World Journal

18. Detecting anxiety in individuals with Parkinson disease: A systematic review

. Pooled prevalence of anxiety was calculated using Mantel-Haenszel-weighted DerSimonian and Laird models.A total of 6,300 citations were reviewed with 6 full-text articles included for synthesis. Tools included within this study were the Beck Anxiety Inventory, Geriatric Anxiety Inventory (GAI), Hamilton Anxiety Rating Scale, Hospital Anxiety and Depression Scale-Anxiety, Parkinson's Anxiety Scale (PAS), and Mini-Social Phobia Inventory. Anxiety diagnoses made included generalized anxiety disorder (...) Detecting anxiety in individuals with Parkinson disease: A systematic review To examine diagnostic accuracy of anxiety detection tools compared with a gold standard in outpatient settings among adults with Parkinson disease (PD).A systematic review was conducted. MEDLINE, EMABASE, PsycINFO, and Cochrane Database of Systematic Reviews were searched to April 7, 2017. Prevalence of anxiety and diagnostic accuracy measures including sensitivity, specificity, and likelihood ratios were gathered

2018 EvidenceUpdates

19. Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders

Psychiatry 2014, 14(Suppl 1):S1 http://www.biomedcentral.com/1471-244X/14/S1/S1 Page 8 of 83no functional impairment in fully recovered patients as measured by a scale such as the Sheehan Disability Scale or SF-36 [32,119,120]. Objective scales can be used to help assess a patient’s progress. The Clinical Global Impression (CGI) scale is brief, comprehensive, and can easily be used at each appointment to assess improvement. The clinician-rated Hamilton Anxiety Rating Scale (HARS) can assess anxi- ety (...) symptoms in general and is often used in clinical trials but is less practical in clinical practice. A variety of self-report and clinician-rated scales are available to assess the specific anxiety or related disorder. Panic disorder and agoraphobia Epidemiology The lifetime and 12-month prevalence of panic disorder have been estimated at 4.7-5.1% and 2.1-2.8%, respec- tively [121,122]. The estimated prevalence of panic attacks is considerably greater at 28.3% (lifetime) and 6.4-11.2% (12-month

2014 CPG Infobase

20. Second Generation Antidepressants for Pediatric patients with Major Depressive Disorder and Anxiety Disorder

Hamilton depression rating scale (HDRS, HAM-D), children?s depression rating scale (CDRS), clinical global impression (CGI), Pediatric anxiety rating scale (PARS), multidimensional anxiety scale for children (SCARED)) Clinical harms (including long-term harms) Study Designs Systematic reviews, meta-analyses, randomized controlled trials, nonrandomized studies Second Generation Antidepressants for Pediatric Patients 4 Exclusion Criteria Articles were excluded if there were a duplicate report of the same (...) on sertraline (62%), no between-group differences were observed for the clinical efficacy parameters, such as: final Hamilton Rating Scale for Depression (HAM-D) scores or relapse-free probability when adjusted by gender and baseline HAM-D scores. 28 In contrast, Emslie et al. 29 noted that the adjusted risk ratio for relapse for patients on placebo compared to fluoxetine was 2.2 (95% CI 1.2 to 3.8 P = 0.005). The probability of relapse was higher for the placebo group at both week 6 (placebo 38.7% vs

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

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