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181. Platelet-rich plasma and microneedling improves hair growth in patients ofandrogenetic alopecia when used as an adjuvant to minoxidil. (PubMed)

Platelet-rich plasma and microneedling improves hair growth in patients ofandrogenetic alopecia when used as an adjuvant to minoxidil. Platelet-rich plasma (PRP) is a popular procedure for the treatment of androgenetic alopecia (AGA).To ascertain the role of minoxidil 5% lotion alone versus minoxidil 5% lotion and PRP versus minoxidil 5% lotion, PRP with microneedling in AGA.Ninety-three AGA patients with Hamilton-Norwood score 1-5 were grouped into three groups A, B, and C. Patients in group (...) and experience. Hair pull test was performed before and during follow-up.Post-treatment, hair pull test was negative in 27 patients (87.1%, P < 0.01) of group C, 20 patients (64.5%, P < 0.05) of group B, and 15 patients (48.4%) of group A. Hair growth was better appreciated in group C (26/31) compared to groups B (17/31)and A (10/31).The patients' self-satisfaction score on a Likert scale was more than seven (high satisfaction) in 24/31 patients in group C. There was a statistically significant difference

2019 Journal of cosmetic dermatology Controlled trial quality: uncertain

182. Re: Impact of Hair Removal on Surgical Site Infection Rates: A Prospective Randomized Noninferiority Trial. (PubMed)

Re: Impact of Hair Removal on Surgical Site Infection Rates: A Prospective Randomized Noninferiority Trial. 28505909 2019 01 29 2019 01 29 1527-3792 197 6 2017 06 The Journal of urology J. Urol. Re: Impact of Hair Removal on Surgical Site Infection Rates: A Prospective Randomized Noninferiority Trial. 1462-1463 S0022-5347(17)39267-4 10.1016/j.juro.2017.03.050 Penson David F DF eng Journal Article Comment 2017 03 15 United States J Urol 0376374 0022-5347 AIM IM J Am Coll Surg. 2016 Nov;223(5 (...) ):704-711 27687471 Hair Removal Humans Preoperative Care Prospective Studies Surgical Wound Infection Time Factors 2017 5 17 6 0 2017 5 17 6 0 2019 1 30 6 0 ppublish 28505909 S0022-5347(17)39267-4 10.1016/j.juro.2017.03.050

2019 The Journal of urology Controlled trial quality: uncertain

183. Re: Impact of Hair Removal on Surgical Site Infection Rates: A Prospective Randomized Noninferiority Trial. (PubMed)

Re: Impact of Hair Removal on Surgical Site Infection Rates: A Prospective Randomized Noninferiority Trial. 29539908 2019 01 28 2019 01 28 1527-3792 197 5 2017 05 The Journal of urology J. Urol. Re: Impact of Hair Removal on Surgical Site Infection Rates: A Prospective Randomized Noninferiority Trial. 1278 S0022-5347(17)30222-7 10.1016/j.juro.2017.02.018 Wang David S DS eng Journal Article Comment 2017 02 09 United States J Urol 0376374 0022-5347 AIM IM J Am Coll Surg. 2016 Nov;223(5):704-711 (...) 27687471 Hair Removal Humans Preoperative Care Prospective Studies Surgical Wound Infection Time Factors 2018 3 16 6 0 2018 3 16 6 0 2019 1 29 6 0 ppublish 29539908 S0022-5347(17)30222-7 10.1016/j.juro.2017.02.018

2019 The Journal of urology Controlled trial quality: uncertain

184. Contact allergy to hair cosmetic allergens in Thailand. (PubMed)

Contact allergy to hair cosmetic allergens in Thailand. Hair cosmetics such as hair dyes, bleaching, waving, and cleansing products are composed of numerous chemical ingredients. Allergic reactions to these contact allergens, other than p-phenylenediamine, are rarely reported.To study the incidence of patch test reactions to hair cosmetic allergens and identify the factors associated with hair cosmetic allergy in Thailand.We retrospectively reviewed the case records of patients who underwent (...) patch testing from 2009 to 2018. Patients with at least one positive patch test reaction to a potential contact allergen associated with hair cosmetic ingredients were studied.Overall, 2842 patients were patch tested. Of the hair cosmetic allergen categories, preservatives had the highest rate of positive reactions, followed by surfactants and hair dyes. Perming agents were less problematic in comparison. The hands, head, and neck were the predominately affected sites of allergic reactions to hair

2019 Contact Dermatitis

185. Lasers for Reduction of Unwanted Hair in Skin of Color: A Systematic Review and Meta-analysis. (PubMed)

Lasers for Reduction of Unwanted Hair in Skin of Color: A Systematic Review and Meta-analysis. Light-based therapies are one of the most effective and widely used strategies for removal of undesired hair, with a broadly favorable safety profile. However, subjects with pigmented skin are found to be more prone to laser-related adverse events. While prolonged pulse-width and longer treatment duration were proposed to minimize adverse events, the optimal treatment option among available (...) phototherapy modalities-long-pulsed (Nd: YAG), pulsed diode, and alexandrite lasers as well as intense pulsed light (IPL)-remains unclear, particularly for skin of color. To determine superiority in terms of effectiveness and tolerability, we conducted a systematic review of literature on different types of in-office laser and IPL for hair removal in subjects with Fitzpatrick skin types III-VI. The meta-analysis was performed using Review Manager (RevMan) version 5.3 and included 12 eligible comparative

2019 Journal of the European Academy of Dermatology and Venereology

186. Associations of plasma, RBCs, and hair carbon and nitrogen isotope ratios with fish, meat, and sugar-sweetened beverage intake in a 12-wk inpatient feeding study. (PubMed)

Associations of plasma, RBCs, and hair carbon and nitrogen isotope ratios with fish, meat, and sugar-sweetened beverage intake in a 12-wk inpatient feeding study. Naturally occurring carbon and nitrogen stable isotope ratios [13C/12C (CIR) and 15N/14N (NIR)] are promising dietary biomarkers. As these candidate biomarkers have long tissue residence times, long-term feeding studies are needed for their evaluation.Our aim was to evaluate plasma, RBCs, and hair CIR and NIR as biomarkers of fish (...) % fat, 20% protein). Fasting blood samples were taken biweekly from baseline, and hair samples were collected at baseline and postintervention. Data were analyzed using multivariable regression.The postintervention CIR of plasma was elevated when diets included meat (β = 0.89, 95% CI: 0.73,1.05) and SSBs (β = 0.48, 95% CI: 0.32, 0.64). The postintervention NIR of plasma was elevated when diets included fish (β = 0.85, 95% CI: 0.64, 1.05) and meat (β = 0.61, 95% CI: 0.42, 0.8). Results were similar

2019 American Journal of Clinical Nutrition

187. The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses. (PubMed)

The Nitrogen Isotope Ratio Is a Biomarker of Yup'ik Traditional Food Intake and Reflects Dietary Seasonality in Segmental Hair Analyses. The nitrogen isotope ratio (NIR) is a promising index of traditional food intake for an Alaska Native (Yup'ik) population, which can be measured in blood and hair. However, the NIR has not been calibrated to high-quality measures of Yup'ik traditional food intake.Our primary objective was to examine associations between intakes of Yup'ik traditional food (...) groups, including fish, marine mammals, birds, land mammals, berries, greens, and total traditional foods, and the NIR. In an exploratory analysis, we also examined whether NIR analyzed sequentially along hair could reflect dietary seasonality.We recruited 68 participants from 2 Yup'ik communities in the Yukon Kuskokwim region of Southwest Alaska (49% female, aged 14-79 y). Participants completed 4 unscheduled 24-h food recalls over the period peak of RBC and hair synthesis preceding a specimen

2019 Journal of Nutrition

188. Splitting hairs and challenging guidelines: Defining the role of perioperative antibiotics in pediatric appendicitis patients. (PubMed)

Splitting hairs and challenging guidelines: Defining the role of perioperative antibiotics in pediatric appendicitis patients. Ambiguity regarding timing and duration of perioperative IV antibiotics in AA and CA exists. We wanted to determine if an association existed between surgical site infections (SSI) in children with acute (AA) or complicated appendicitis (CA) and timing and duration of perioperative antibiotics.We performed a single institution, case control observational study

2019 Journal of Pediatric Surgery

189. Understanding curly hair mechanics: Fibre strength. (PubMed)

Understanding curly hair mechanics: Fibre strength. The relationship between the geometric and mechanical profiles of hair fibres has been studied, with special focus on curly samples. Incidental observations pointed to a significantly different viscoelastic character with varying curliness. Further investigations confirmed initial observations, showing an initial distinct toe-region behaviour for curly-fibres on the stress-strain plot, which is absent for straight fibres. This behaviour (...) suggested a difference in viscoelastic nature of the curly fibre that is linked to mechanical energy stored in the fibre. Results also suggest that the strength of hair depends on two main components, and further pointed out that de facto methods of tensile testing may erode curly fibre strength during preparation. The main outcome of this study is that the tensile strength (σT), of hair fibres is composed of two (rather than one main) components, namely the toe-region (σt) and the elastic region (σε

2019 Journal of Investigative Dermatology

190. CD49f<sup>high</sup> Defines A Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance. (PubMed)

CD49fhigh Defines A Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance. Dermis harbor distinct mesenchymal stem cell populations, which play equally important roles as epidermal stem cells in skin homeostasis and regeneration. However, to reliably identify and directly isolate the in vivo counterpart of these cells is still challenging. Using the epidermal stem cell marker CD49f, we defined CD49fhigh distinct mesenchymal subpopulation (...) in the dermis. In vitro and in vivo differentiation assays and transcriptome analysis demonstrated that CD49fhigh cells possess neural crest-like cell characteristics. Further results showed that the formation of hair follicle-like budding structure and the expressions of key genes regulating hair follicle development were induced when hair follicle epithelial cells were co-cultured with CD49fhigh cells. Moreover, we found that CD49fhigh cells activated Notch signaling in co-cultured hair follicle

2019 Journal of Investigative Dermatology

191. "Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen effluvium in women". (PubMed)

"Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen effluvium in women". Miliacin, the main triterpenoid from millet, is known to stimulate keratinocyte metabolism and proliferation. Polar lipids are able to form vesicles with active compounds and to improve their bioavailability.We aimed to demonstrate potential benefits of a solution of miliacin encapsulated within polar lipids (MePL) on telogen effluvium prevention and hair condition (...) in women.After preliminary cell proliferation studies, a placebo-controlled, multicentric, randomized, double-blind trial was performed on sixty-five nonmenopausal women affected by telogen effluvium, to assess the efficacy of a 12-week oral supplementation with MePL. Telogen and anagen densities were determined by phototrichogram analysis. Scalp dryness and hair brightness were clinically evaluated using a Likert scale.MePL further enhanced cell proliferation in hair bulb from human scalp than miliacin

2019 Journal of cosmetic dermatology Controlled trial quality: predicted high

192. Comparison of efficacy and safety of a novel 755-nm diode laser with conventional 755-nm alexandrite laser in reduction of axillary hairs. (PubMed)

Comparison of efficacy and safety of a novel 755-nm diode laser with conventional 755-nm alexandrite laser in reduction of axillary hairs. The aim of this study was to compare the efficacy and safety of a novel diode system emitting 755 nm wavelength with conventional 755 nm alexandrite laser in skin types III and IV. It was a randomized, right-left comparison, assessor-blind, clinical study. Sixteen female volunteers age 29.52 ± 9.52 were randomly assigned to receive six treatment sessions (...) using 755 nm diode laser on one axilla and 755 nm alexandrite on the opposite axilla. Efficacy was assessed by counting of hairs per square centimeter, 6 months after the last treatment. Treatment outcome was also evaluated by blind reviewing of before and after pictures, using Physician Global Assessment scale (GAS). Subject satisfaction was assessed using visual analogue scale (VAS), pain level and adverse effects were recorded. Skin biophysical parameters (transepidermal water loss, skin sebum

2019 Lasers in medical science Controlled trial quality: uncertain

193. Comparing the Effects of Zinc Sulfate, Calcium Pantothenate, Their Combination and Minoxidil Solution Regimens on Controlling Hair Loss in Women: A Randomized Controlled Trial. (PubMed)

Comparing the Effects of Zinc Sulfate, Calcium Pantothenate, Their Combination and Minoxidil Solution Regimens on Controlling Hair Loss in Women: A Randomized Controlled Trial. This study was conducted to evaluate the combination of oral supplements with 2% minoxidil solution in four groups of women with hair loss.A prospective, randomized controlled trial was conducted from July to December 2016 in dermatology clinics affiliated to Isfahan University of Medical Sciences. A total of 73, 15-45 (...) -year-old, women with hair loss participated in this 4-month study. Simple randomization using Random Allocation Software was done to put the participants in four groups to receive coadministration of zinc sulfate and calcium pantothenate, zinc sulfate, calcium pantothenate, and 2% minoxidil solution. The primary endpoint was the change in hair density and diameter measured by dermatoscope. Secondary endpoints included the researcher's evaluation, dermatologist's opinion - which was blinded

2019 Journal of research in pharmacy practice Controlled trial quality: uncertain

194. Noncultured Extracted Hair Follicle Outer Root Sheath Cell Suspension versus Noncultured Epidermal Cell Suspension in the Treatment of Stable Vitiligo. (PubMed)

Noncultured Extracted Hair Follicle Outer Root Sheath Cell Suspension versus Noncultured Epidermal Cell Suspension in the Treatment of Stable Vitiligo. Various treatment modalities exist for vitiligo, yet none of them are curative. Vitiligo is still considered a challenging disease to manage. Surgical treatment offers an excellent option for patients with stable vitiligo, especially those who fail to respond to medical treatment. Cell suspension techniques carry the advantage of covering large (...) surface areas.To compare noncultured extracted hair follicle outer root sheath cell suspension (NCORSHFS) and noncultured epidermal cell suspension (NCES) in producing repigmentation.Twenty patients were randomly allocated into two groups. They were objectively evaluated for the extent of repigmentation (after 1, 2, and 3 months), complications, cosmetic outcome, and satisfaction.In NCORSHFS group, 10% showed excellent pigmentation, 20% showed good pigmentation, 50% fair, and 20% poor pigmentation

2019 Journal of cutaneous and aesthetic surgery Controlled trial quality: uncertain

195. Minoxidil 1 mg Orally versus Minoxidil 5% Solution Topically for the Treatment of Female Pattern Hair Loss: A Randomized Clinical Trial. (PubMed)

Minoxidil 1 mg Orally versus Minoxidil 5% Solution Topically for the Treatment of Female Pattern Hair Loss: A Randomized Clinical Trial. 31473295 2019 09 01 1097-6787 2019 Aug 29 Journal of the American Academy of Dermatology J. Am. Acad. Dermatol. Minoxidil 1 mg Orally versus Minoxidil 5% Solution Topically for the Treatment of Female Pattern Hair Loss: A Randomized Clinical Trial. S0190-9622(19)32666-0 10.1016/j.jaad.2019.08.060 Ramos Paulo Müller PM Dermatologist, M.D.; MSc, Departamento de (...) Journal Article 2019 08 29 United States J Am Acad Dermatol 7907132 0190-9622 IM Female pattern hair loss androgenetic alopecia hypertrichosis minoxidil oral topical treatment 2019 02 10 2019 08 10 2019 08 22 2019 9 2 6 0 2019 9 2 6 0 2019 9 2 6 0 aheadofprint 31473295 S0190-9622(19)32666-0 10.1016/j.jaad.2019.08.060

2019 Journal of the American Academy of Dermatology Controlled trial quality: uncertain

196. Novel shampoo reduces hair shedding by contracting the arrector pili muscle via the trace amine-associated receptor. (PubMed)

Novel shampoo reduces hair shedding by contracting the arrector pili muscle via the trace amine-associated receptor. Approximately 40% of women experience excessive hair shedding when washing their hair. Previously, we have demonstrated that a topically applied α1 adrenergic receptor agonist can be used to contract the arrector pili muscle of the follicular unit (ie, produce "goose bumps"), increasing the force required to pluck hair by as much as 400%. Subsequently, we reported a topical (...) cosmetic solution containing an α1 adrenergic receptor agonist that reduced hair shedding during brushing by a maximum of 77%.In this communication, we explore a novel mechanism to contract the arrector pili muscle. Trace amine-associated receptors (TAAR) have been shown to regulate smooth muscle tone in blood vessels, but have not been reported to be present in the skin. Here, we report on the anti-shedding efficacy of a shampoo containing a selective TAAR agonist, tyramine hydrochloride.A single

2019 Journal of cosmetic dermatology Controlled trial quality: uncertain

197. Comparing the Efficacy of Mesotherapy to Topical Minoxidil in the Treatment of Female Pattern Hair Loss Using Ultrasound Biomicroscopy: A Randomized Controlled Trial. (PubMed)

Comparing the Efficacy of Mesotherapy to Topical Minoxidil in the Treatment of Female Pattern Hair Loss Using Ultrasound Biomicroscopy: A Randomized Controlled Trial. The efficacy of mesotherapy in the treatment of female pattern hair loss (FPHL) has not yet been evaluated. Aim of the study was to compare the initial efficacy and safety of mesotherapy containing nutritional supplements to topical minoxidil 5% solution in FPHL. 30 patients with FPHL were randomly classified into two equal groups (...) : Group A applied minoxidil 5% lotion twice daily; Group B was injected with mesotherapy once weekly. For both groups ultrasound biomicroscopy (UBM) was performed before and at the end of the 12th week of treatment. After treatment, no significant difference was found between both groups with regard to either improvement of hair density and hair loss (P=0.27 and 0.056, respectively), nor the degree of improvement of Ludwig's classification as assessed by the investigator (P=0.210). A significant

2019 Acta dermatovenerologica Croatica : ADC Controlled trial quality: uncertain

198. Correlation of hair and plasma efavirenz concentrations in HIV-positive South Africans. (PubMed)

Correlation of hair and plasma efavirenz concentrations in HIV-positive South Africans. Antiretroviral concentrations in hair provide a longer window of drug detection and are useful for measuring longer-term drug exposure. Efavirenz is an important component of first-line treatment in resource-limited settings, but its concentrations in hair have not been well studied.This study is a supplementary to a randomised controlled trial of an adherence intervention using an electronic adherence (...) measuring device. Hair and plasma samples were collected from human immunodeficiency virus-positive patients in Cape Town, South Africa. Previously validated liquid chromatography tandem mass spectrometry methods were used to measure efavirenz concentrations in the collected hair and plasma samples. CYP2B6 genotyping of participants was also performed. Data analysis was performed using descriptive and comparative statistics as well as regression modelling.Hair samples were collected from 59% of patients

2019 Southern African journal of HIV medicine Controlled trial quality: uncertain

199. Hair micro transplant using follicular unit extraction technique for alopecia

Hair micro transplant using follicular unit extraction technique for alopecia Hair micro transplant using follicular unit extraction technique for alopecia Hair micro transplant using follicular unit extraction technique for alopecia Macchiavello D, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A, López A, Rey-Ares L., Hernandez Vásquez A Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA (...) . No evaluation of the quality of this assessment has been made for the HTA database. Citation Macchiavello D, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A, López A, Rey-Ares L., Hernandez Vásquez A. Hair micro transplant using follicular unit extraction technique for alopecia. Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Documentos de Evaluación de Tecnologías Sanitarias, Informe de Respuesta Rápida N° 444, Buenos Aires, Argentina

2015 Health Technology Assessment (HTA) Database.

200. Laser hair removal for prevention of pilonidal sinus recurrence

Laser hair removal for prevention of pilonidal sinus recurrence Laser hair removal for prevention of pilonidal sinus recurrence Laser hair removal for prevention of pilonidal sinus recurrence Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Laser hair removal for prevention of pilonidal sinus recurrence. Lansdale: HAYES, Inc.. Healthcare Technology Brief (...) Publication. 2014 Authors' conclusions Pilonidal disease is a pathologic condition characterized by at least 1 abnormal pocket (sinus) or cyst located under the skin and filled with hair and skin debris. It is an acquired condition related to the presence of hair in the natal cleft, caused either by a reaction to loose hair that has penetrated and embedded in the skin or a reaction to a rupture of a hair follicle that may occur with stretching of the deep layers of skin or with the hormone-induced changes

2014 Health Technology Assessment (HTA) Database.

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