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HIV Course

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15701. Developing a national HIV/AIDS Prevention Program through state health departments. (PubMed)

Developing a national HIV/AIDS Prevention Program through state health departments. The Centers for Disease Control (CDC) shaped the basic development and direction of the HIV/AIDS Prevention Program through technical support and financial assistance for State and local health departments and other organizations. Through this provision of support, CDC has responded to the course of the human immunodeficiency virus (HIV)-acquired immunodeficiency syndrome (AIDS) epidemic by creating programs

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1991 Public Health Reports

15702. HIV safety guidelines and laboratory training. NIOSH. (PubMed)

HIV safety guidelines and laboratory training. NIOSH. At the Centers for Disease Control (CDC), educational activities concerning acquired immunodeficiency syndrome (AIDS) are directed to many target audiences; important among these are health care and public safety workers. Several CDC programs are designed to address the specific education and training needs of these groups. The National Institute for Occupational Safety and Health (NIOSH) has developed a set of occupational safety guidelines (...) directed to fire service personnel, emergency medical technicians, paramedics, and law enforcement and correctional facility personnel. These guidelines provide information on modes of transmission of human immunodeficiency virus (HIV) in the workplace, the risk of transmission, the control of risk, and specific risk-control recommendations. NIOSH also has developed a model curriculum, based on the principles and practices discussed in the guidelines, for use in training workers. The Hospital

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1991 Public Health Reports

15703. Murine immune response to HIV-1 p24 core protein following subcutaneous, intraperitoneal and intravenous immunization. (PubMed)

Murine immune response to HIV-1 p24 core protein following subcutaneous, intraperitoneal and intravenous immunization. The murine immune response to baculovirus-produced human immunodeficiency virus type-1 (HIV-1)p24 was examined after injection by three different routes: subcutaneously (s.c.), intraperitoneally (i.p.) and intravenously (i.v.). Both antigen-specific T-cell proliferation and serum antibody were induced by i.p. injection. In contrast, s.c. and i.v. injection of antigen resulted (...) . administration of high doses of antigen, the median antibody titres continued to rise after a third injection, but plateaued in animals injected by the i.p. route. In contrast, low doses of antigen given i.p. increased the median titre during and after the course of four injections. A low antigen dose given s.c. resulted in a plateau of median titre between the third and fourth injections. In i.v.-injected animals the median titre decreased between the third and fourth injections. IgG1 p24-specific

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1991 Immunology

15704. Pursuit eye movement dysfunction in HIV-1 seropositive individuals. (PubMed)

Pursuit eye movement dysfunction in HIV-1 seropositive individuals. Studies of smooth pursuit eye movements were conducted in 30 ambulatory drug-free HIV-1 seropositive patients who did not yet manifest marked clinical signs of the AIDS Dementia Complex. Seropositive patients demonstrated disturbances in pursuit eye movements that were correlated with extent of immunosuppression, with impairments on neuropsychological tests of fine motor control/speed, and with independent clinical staging (...) of the AIDS Dementia Complex. The results provide quantitative evidence that oculomotor disturbances are present in HIV-1 seropositive individuals before the manifestation of marked AIDS Dementia Complex. For this reason, and because more severe eye movement impairments have been observed in patients with AIDS, quantitative eye movement studies may provide a useful neurobehavioral procedure for characterizing and monitoring progression of CNS involvement associated with HIV-1 infection from early in its

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1991 Journal of Psychiatry and Neuroscience

15705. Cutaneous hypersensitivity reactions due to thiacetazone in the treatment of tuberculosis in Zambian children infected with HIV-I. (PubMed)

(1 April 1990 to 31 October 1991) in 237 children with a clinical diagnosis of tuberculosis (125 boys and 112 girls; 88/237 (37%) infected with HIV-I) and 242 control children (149 boys and 93 girls; 26/242 (11%) infected with HIV-I). Twenty two (9%) of the 237 children with tuberculosis developed hypersensitivity skin reactions during the course of treatment. Adverse skin reactions were seen more often in children infected with HIV than in those who were not (odds ratio 11.65, 95% confidence (...) Cutaneous hypersensitivity reactions due to thiacetazone in the treatment of tuberculosis in Zambian children infected with HIV-I. Tuberculosis is one of the most common infections in Zambian adults and children infected with HIV. In Africa, cutaneous hypersensitivity reactions attributed to thiacetazone during treatment of tuberculosis in adults infected with HIV-I have been well documented. This study monitored adverse drug reactions during treatment for tuberculosis over an 18 month period

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1993 Archives of Disease in Childhood

15706. Changes in sexual behaviour and the fall in incidence of HIV infection among homosexual men. (PubMed)

Changes in sexual behaviour and the fall in incidence of HIV infection among homosexual men. To investigate the epidemiology and normal course of infection with HIV the prevalence and incidence of the infection were studied among two cohorts of homosexual men in Amsterdam in 1980-7. The cumulative incidence of infection increased from a weighted 2.2% in 1980 to 39.0% in 1987. The estimated yearly incidence of HIV was 3.0% in 1981, rose to 8.8% in 1984, and fell gradually to 0% in 1987. During (...) the study the sexual behaviour of the cohorts was examined. The number of men with whom anopenetrative intercourse was practised fell from a mean of 10.6 to 1.4 for those positive for HIV antibody, whereas the number with whom anoreceptive intercourse was practised fell from a mean of 3.7 to 0.5 for those negative for the antibody. In addition, there was a reduction in the number of cases of hepatitis B and syphilis among men in general. The decline in infection with HIV was assumed to be linked

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1989 BMJ : British Medical Journal

15707. Outcome of untreated infection with Entamoeba histolytica in homosexual men with and without HIV antibody. (PubMed)

Outcome of untreated infection with Entamoeba histolytica in homosexual men with and without HIV antibody. Among homosexual men the prevalence of infection with Entamoeba histolytica is high. To determine the clinical importance of this infection 55 homosexual men carrying the parasite were investigated in detail. No clinical, serological, or histological evidence of invasive amoebiasis was found in any of them. The patients were not treated and were followed up for 12 to 29 months (mean 21.6 (...) months), during which period none developed symptoms that could be attributed to E histolytica. Spontaneous loss of the parasite occurred in 17 patients, some of whom later became reinfected. Sixteen patients had antibody to human immunodeficiency virus, and infection with E histolytica showed the same benign course in them as in the patients who did not have antibody. Throughout the study classification of the isolates of E histolytica consistently showed that they belonged only to non-pathogenic

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1988 BMJ : British Medical Journal

15708. Sexual behavior changes and HIV antibody in a cohort of New York City gay men. (PubMed)

Sexual behavior changes and HIV antibody in a cohort of New York City gay men. A sample of 357 gay/bisexual men, ages 20 to 65, were interviewed in 1985 regarding their sexual patterns over the course of the AIDS (acquired immunodeficiency syndrome) epidemic. Within four months after the interview, men were tested for antibody to HIV (human immunodeficiency virus) and 36 per cent were found positive. Cessation of receptive anal intercourse was associated with HIV negative antibody status (...) , (OR greater than 3.0). Reducing the number of sexual partners, becoming monogamous, or eliminating other forms of sexual contact were not related to risk of HIV.

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1989 American Journal of Public Health

15709. Significant Genetic and Antigenic Variability within the env Gene of Systemic Human Immunodeficiency Virus Type 1 Group O Populations during the Natural Course of a Heterosexual Infection: a Pilot Study (PubMed)

Significant Genetic and Antigenic Variability within the env Gene of Systemic Human Immunodeficiency Virus Type 1 Group O Populations during the Natural Course of a Heterosexual Infection: a Pilot Study We assessed the genetic and the antigenic variability within the env gene of peripheral blood human immunodeficiency virus (HIV) type 1 (HIV-1) group O populations during the natural course of a female heterosexual infection. Our data revealed the existence of a significant increase in amino (...) acid sequence variability within the C2-V3 and gp41 regions (P = 0.023 and P < 0.001, respectively) in association with substitutions within neutralizing epitope sequences usually selected for HIV serological assays. These antigenic variations might significantly decrease the sensitivity of classical HIV enzyme-linked immunosorbent assays with blood samples of subjects heterosexually infected by HIV-1 group O strains. These findings may be of significant use both to devise diagnostic tools

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2007 Journal of clinical microbiology

15710. A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome

of second course of betamethasone Already receiving corticosteroids for other conditions (e.g. Lupus, asthma) Maternal condition contraindicating the use of steroids (e.g. HIV, active Tuberculosis) Participation in conflicting study Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov (...) A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2005 Clinical Trials

15711. Safety and Tolerability of Repeat Courses of IM Alefacept

Safety and Tolerability of Repeat Courses of IM Alefacept Safety and Tolerability of Repeat Courses of IM Alefacept - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Safety and Tolerability of Repeat Courses (...) is to determine whether repeat courses of alefacept, administered intramuscularly, are safe when given to chronic plaque psoriasis patients who are receiving standard dermatology treatments. Condition or disease Intervention/treatment Phase Chronic Plaque Psoriasis Drug: Alefacept Phase 3 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Enrollment : 400 participants Allocation: Non-Randomized Intervention Model: Single Group Assignment Masking: None (Open

2005 Clinical Trials

15712. Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia

Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00260819 Recruitment Status : Completed First Posted : December 2, 2005 Last Update Posted : October 17, 2008 Sponsor

2005 Clinical Trials

15713. Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease

Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease (BIOAIR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00555607 Recruitment Status : Active, not recruiting First Posted : November 8, 2007 Last Update Posted : March 20, 2018

2007 Clinical Trials

15714. Short Course of Miltefosine and Antimony to Treat Cutaneous Leishmaniasis in Bolivia

Short Course of Miltefosine and Antimony to Treat Cutaneous Leishmaniasis in Bolivia Short Course of Miltefosine and Antimony to Treat Cutaneous Leishmaniasis in Bolivia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Short Course of Miltefosine and Antimony to Treat Cutaneous Leishmaniasis in Bolivia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00537953 Recruitment Status : Unknown Verified September 2007 by Centro de Investigaciones Bioclínicas de la Fundación Fader. Recruitment status

2007 Clinical Trials

15715. [Short-course isoniazid and rifampin compared with isoniazid for latent tuberculosis infection: a randomized clinical trial]. (PubMed)

[Short-course isoniazid and rifampin compared with isoniazid for latent tuberculosis infection: a randomized clinical trial]. The aim of this study was to compare the adherence to, and side effects of a 3-month short-course treatment for latent tuberculosis infection as compared to the standard 6-month course.Prospective, comparative, randomized, open trial including patients with a positive tuberculin skin test and appropriate criteria for treatment in accordance with the CDC guidelines (...) , and excluding patients with HIV infection. Group I (6H) was assigned to isoniazid 300 mg per day for 6 months and Group II (3HR) was assigned to isoniazid 300 mg per day plus rifampin 600 mg per day for 3 months. The patients were followed up for five years.A total of 105 patients were included, among which 9 refused treatment; 45 patients were placed in Group I and 51 patients in Group II. Both groups were comparable at baseline. Hepatotoxicity was 44% in Group 6H and 29% in Group 3HR (P = 0.07

2007 Enfermedades infecciosas y microbiología clínica

15716. A Phase II Study To Assess Safety and Efficacy Of Short-Course Regimens Of Amphotericin B Emulsion In Kala-Azar

A Phase II Study To Assess Safety and Efficacy Of Short-Course Regimens Of Amphotericin B Emulsion In Kala-Azar A Phase II Study To Assess Safety and Efficacy Of Short-Course Regimens Of Amphotericin B Emulsion In Kala-Azar - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved (...) studies (100). Please remove one or more studies before adding more. A Phase II Study To Assess Safety and Efficacy Of Short-Course Regimens Of Amphotericin B Emulsion In Kala-Azar The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00497601 Recruitment Status : Completed First Posted : July 6, 2007 Last

2007 Clinical Trials

15717. Time Course of the Antiproteinuric and Blood Pressure Lowering Effects After Initiation of Renin Inhibition With Aliskiren in Type 2 Diabetes

Time Course of the Antiproteinuric and Blood Pressure Lowering Effects After Initiation of Renin Inhibition With Aliskiren in Type 2 Diabetes Time Course of the Antiproteinuric and Blood Pressure Lowering Effects After Initiation of Renin Inhibition With Aliskiren in Type 2 Diabetes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Time Course of the Antiproteinuric and Blood Pressure Lowering Effects After Initiation of Renin Inhibition With Aliskiren in Type 2 Diabetes The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details

2007 Clinical Trials

15718. Short-Course Isoniazid and Rifampin Compared With Isoniazid for Latent Tuberculosis Infection

, in accordance with the guidelines of the CDC, excluding HIV infection. 105 patients were included. In Conclusion, a short course with isoniazid plus rifampin during 3 months shown better compliance with a lower percentage of abandonment that the course 6H. Tolerance is similar in the two courses. Condition or disease Intervention/treatment Phase Tuberculosis Drug: I ( isoniazid), II (isoniazid + rifampin ) Phase 4 Detailed Description: Introduction: The objective of the study was to compare the compliance (...) and the side effects of a short course to treatment of latent tuberculosis infection during 3 months with the standard course for 6 months. Methods: Prospective, comparative, randomized and open trial of patients with positive TST and the suitable criteria for treatment, in accordance with the guidelines of the CDC, excluding HIV infection. the group I was assigned to isoniazid (H) at a dose of 300 mg per day for 6 months and the group II was assigned to isoniazid at a dose of 300 mg per day plus rifampin

2006 Clinical Trials

15719. Short Course of Miltefosine and Liposomal Amphotericin B for Kala-azar

Short Course of Miltefosine and Liposomal Amphotericin B for Kala-azar Short Course of Miltefosine and Liposomal Amphotericin B for Kala-azar - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Short Course (...) : Non-Randomized Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: The Efficacy and Safety of a Short Course of Miltefosine and Liposomal Amphotericin B for Visceral Leishmaniasis in India Study Start Date : October 2007 Actual Primary Completion Date : August 2009 Actual Study Completion Date : February 2010 Resource links provided by the National Library of Medicine related topics: available for: resources: Arms and Interventions Go

2006 Clinical Trials

15720. Effectiveness of Short-Course Versus Standard Antibiotic Therapy in ICU Patients

Effectiveness of Short-Course Versus Standard Antibiotic Therapy in ICU Patients Effectiveness of Short-Course Versus Standard Antibiotic Therapy in ICU Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) more. Effectiveness of Short-Course Versus Standard Antibiotic Therapy in ICU Patients The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00410527 Recruitment Status : Completed First Posted : December 13, 2006 Last Update Posted : July 2, 2017 Sponsor: National Institutes of Health Clinical Center (CC

2006 Clinical Trials

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