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3201. Multiple sclerosis: hyperintense lesions in the brain on nonenhanced T1-weighted MR images evidenced as areas of T1 shortening. (PubMed)

Multiple sclerosis: hyperintense lesions in the brain on nonenhanced T1-weighted MR images evidenced as areas of T1 shortening. To retrospectively document hyperintense lesions on nonenhanced T1-weighted magnetic resonance (MR) images in patients with multiple sclerosis (MS) and study their relationship to physical disability, disease course, and other MR markers of tissue damage (brain atrophy).Institutional review board approval was obtained; informed consent was waived for this HIPAA

2007 Radiology

3202. Abduction and external rotation in shoulder impingement: an open MR study on healthy volunteers initial experience. (PubMed)

Abduction and external rotation in shoulder impingement: an open MR study on healthy volunteers initial experience. To prospectively evaluate rotator cuff contact with the glenoid in healthy volunteers placed in the unloaded and loaded abduction and external rotation (ABER) positions in an open magnetic resonance (MR) imager.The study was institutional review board approved and HIPAA compliant, and informed consent was received. Eight male volunteers with no history of shoulder pain

2007 Radiology

3203. Hepatocellular carcinoma with indeterminate or false-negative findings at initial MR imaging: effect on eligibility for curative treatment initial observations. (PubMed)

Hepatocellular carcinoma with indeterminate or false-negative findings at initial MR imaging: effect on eligibility for curative treatment initial observations. To retrospectively evaluate the effect of indeterminate or false-negative findings at magnetic resonance (MR) imaging on eligibility for curative treatment of hepatocellular carcinoma (HCC).This HIPAA-compliant retrospective study was approved by the institutional review board; the need for informed consent was waived. Of 166 patients

2007 Radiology

3204. Breast lesions: imaging with contrast-enhanced subharmonic US--initial experience. (PubMed)

Breast lesions: imaging with contrast-enhanced subharmonic US--initial experience. To prospectively compare accuracy of gray-scale subharmonic imaging (SHI) with that of standard gray-scale ultrasonography (US), power Doppler US (with and without contrast material), and mammography for the diagnosis of breast cancer, with histopathologic or clinical follow-up results as the reference standard.This HIPAA-compliant pilot study had institutional review board approval; all subjects gave written

2007 Radiology

3205. CT in the evaluation of nontraumatic abdominal pain in pregnant women. (PubMed)

CT in the evaluation of nontraumatic abdominal pain in pregnant women. To retrospectively determine sensitivity and specificity of computed tomography (CT) for the diagnosis of appendicitis in pregnant women with nontraumatic abdominal pain and retrospectively compare findings at CT and ultrasonography (US) in patients who underwent both examinations, with surgery or clinical follow-up as a reference standard.Institutional review board approval was obtained, and the study was HIPAA compliant

2007 Radiology

3206. Differentiating benign from malignant solid breast masses with US strain imaging. (PubMed)

Differentiating benign from malignant solid breast masses with US strain imaging. To prospectively evaluate the sensitivity and specificity of ultrasonographic (US) strain imaging for distinguishing between benign and malignant solid breast masses, with biopsy results as the reference standard.The study was institutional review board approved and HIPAA compliant. Informed consent was obtained from all participating patients. US strain imaging of 403 breast masses was performed. The 50 malignant

2007 Radiology

3207. Early invasive cervical cancer: CT and MR imaging in preoperative evaluation - ACRIN/GOG comparative study of diagnostic performance and interobserver variability. (PubMed)

Early invasive cervical cancer: CT and MR imaging in preoperative evaluation - ACRIN/GOG comparative study of diagnostic performance and interobserver variability. To retrospectively compare diagnostic performance and interobserver variability for computed tomography (CT) and magnetic resonance (MR) imaging in the pretreatment evaluation of early invasive cervical cancer, with surgical pathologic findings as the reference standard.This HIPAA-compliant study had institutional review board

2007 Radiology

3208. Utilization of diagnostic medical imaging: comparison of radiologist referral versus same-specialty referral. (PubMed)

Utilization of diagnostic medical imaging: comparison of radiologist referral versus same-specialty referral. To retrospectively compare the frequency with which patients underwent diagnostic medical imaging procedures during episodes of outpatient medical care according to whether their physicians referred patients for imaging to themselves and/or physicians in their same specialty or to radiologists.Institutional review board approval was not necessary for this HIPAA-compliant study

2007 Radiology

3209. Blood vessel morphologic changes depicted with MR angiography during treatment of brain metastases: a feasibility study. (PubMed)

obtained for this HIPAA-compliant study. Twenty-two women aged 31-61 years underwent brain MR angiography prior to and 2 months after initiation of lapatinib therapy for brain metastases from breast cancer. Vessels were extracted from MR angiograms with a computer program. Changes in vessel number, radius, and tortuosity were calculated mathematically, normalized with values obtained in 34 healthy control subjects (19 women, 15 men; age range, 19-72 years), and compared with subsequent assessments

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2007 Radiology

3210. Pancreatic adenocarcinoma: value of multidetector CT angiography in preoperative evaluation. (PubMed)

Pancreatic adenocarcinoma: value of multidetector CT angiography in preoperative evaluation. To retrospectively assess the sensitivity and specificity of multidetector computed tomographic (CT) angiography in the preoperative evaluation of pancreatic adenocarcinoma by using surgical findings as the reference standard.The institutional review board approved this HIPAA-compliant study; informed consent was waived. We reviewed CT reports, surgical notes, and pathology reports from 114 patients

2007 Radiology

3211. Pure ductal carcinoma in situ: kinetic and morphologic MR characteristics compared with mammographic appearance and nuclear grade. (PubMed)

Pure ductal carcinoma in situ: kinetic and morphologic MR characteristics compared with mammographic appearance and nuclear grade. To retrospectively compare the kinetic and morphologic characteristics of pure ductal carcinoma in situ (DCIS) lesions depicted on dynamic contrast material-enhanced magnetic resonance (MR) images with the nuclear grade and conventional mammographic appearance of these lesions.This HIPAA-compliant retrospective study was institutional review board approved

2007 Radiology

3212. Bone and soft-tissue sarcoma: preoperative staging with fluorine 18 fluorodeoxyglucose PET/CT and conventional imaging. (PubMed)

Bone and soft-tissue sarcoma: preoperative staging with fluorine 18 fluorodeoxyglucose PET/CT and conventional imaging. To retrospectively compare the diagnostic accuracy of positron emission tomography (PET)/computed tomography (CT), PET, conventional imaging, and combined PET/CT and conventional imaging for tumor staging of bone and soft-tissue sarcomas, by using histologic or follow-up imaging findings as the reference standard.Institutional review board approval was received for this HIPAA

2007 Radiology

3213. Bowel transition points: multiplicity and posterior location at CT are associated with small-bowel volvulus. (PubMed)

Bowel transition points: multiplicity and posterior location at CT are associated with small-bowel volvulus. To retrospectively evaluate the sensitivity and specificity of the number and location of bowel transition points at computed tomography (CT) in the diagnosis of small-bowel volvulus, with surgical findings as the reference standard.This HIPAA-compliant study had institutional review board approval; informed consent was waived. One hundred adult patients who had undergone preoperative CT

2007 Radiology

3214. Enhancing nonmass lesions in the breast: evaluation with proton (1H) MR spectroscopy. (PubMed)

Enhancing nonmass lesions in the breast: evaluation with proton (1H) MR spectroscopy. To prospectively evaluate the sensitivity and specificity of proton (hydrogen 1 [1H]) magnetic resonance (MR) spectroscopy for diagnosing malignant enhancing nonmass lesions identified at breast MR imaging, with histologic examination as the reference standard.In this HIPAA-compliant, institutional review board-approved study, in which all participants gave written informed consent, proton (1H) MR spectroscopy

2007 Radiology

3215. Evaluation of computer-aided detection systems in the detection of small invasive breast carcinoma. (PubMed)

Evaluation of computer-aided detection systems in the detection of small invasive breast carcinoma. To retrospectively compare two CAD systems for detecting invasive breast cancers manifesting as noncalcified masses smaller than 16 mm.Waiver of informed consent was granted by the Institutional Review Board that approved this HIPAA-compliant study. Mammograms obtained from two institutions providing consecutive invasive carcinomas manifesting as noncalcified masses smaller than 16 mm were

2007 Radiology

3216. Computer-aided detection of colorectal polyps: can it improve sensitivity of less-experienced readers? Preliminary findings. (PubMed)

. Institutions from the United States were HIPAA compliant. Written informed consent was waived at all institutions. The CT colonographic studies in 30 patients from six institutions were collected; 24 images depicted at least one confirmed polyp 6 mm or larger (39 total polyps) and six depicted no polyps. By using an investigational software package, seven less-experienced readers from two institutions evaluated the CT colonographic images and marked or scored polyps by using a five-point scale before

2007 Radiology

3217. Cortical deactivation in mild cognitive impairment: high-field-strength functional MR imaging. (PubMed)

Cortical deactivation in mild cognitive impairment: high-field-strength functional MR imaging. To prospectively identify brain regions in which task-related changes in activation during a memory encoding task, measured with functional magnetic resonance (MR) imaging, correlate with degree of memory impairment across Alzheimer disease (AD), mild cognitive impairment (MCI), and elderly control subjects.The institutional review board approved this HIPAA-compliant study, and each patient gave

2007 Radiology

3218. Recent myocardial infarction: assessment with unenhanced T1-weighted MR imaging. (PubMed)

Recent myocardial infarction: assessment with unenhanced T1-weighted MR imaging. The purpose of the study was to prospectively evaluate a T1-weighted technique for detection of myocardial edema resulting from recent myocardial infarction (MI) or intervention. This study was HIPAA compliant and institutional review board approved. Fifteen men and one woman (mean age, 57.8 years+/-11.5 [standard deviation]) were examined with T1-weighted magnetic resonance (MR) imaging and inversion-recovery cine

2007 Radiology

3219. Differentiation between symptomatic Chiari I malformation and asymptomatic tonsilar ectopia by using cerebrospinal fluid flow imaging: initial estimate of imaging accuracy. (PubMed)

of the University of Wisconsin Hospital and Clinics approved our HIPAA-compliant retrospective study and granted a waiver for informed consent. Seventeen patients (five male, 12 female; aged 4-43 years) with tonsils extending more than 5 mm below the foramen magnum were classified by the neurosurgeon as symptomatic for Chiari I malformation or asymptomatic for tonsilar ectopia. The CSF flow images of the two groups were read independently in blinded fashion by four neuroradiologists. Reader agreement

2007 Radiology

3220. Detection of prostate cancer with MR spectroscopic imaging: an expanded paradigm incorporating polyamines. (PubMed)

Detection of prostate cancer with MR spectroscopic imaging: an expanded paradigm incorporating polyamines. To characterize benign and malignant prostate peripheral zone (PZ) tissue retrospectively by using a commercial magnetic resonance (MR) spectroscopic imaging package and incorporating the choline plus creatine-to-citrate ratio ([Cho + Cr]/Cit) and polyamine (PA) information into a statistically based voxel classification procedure.The institutional review board approved this HIPAA

2007 Radiology

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