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3001. Effect of patient weight and scanning duration on contrast enhancement during pulmonary multidetector CT angiography. (PubMed)

Effect of patient weight and scanning duration on contrast enhancement during pulmonary multidetector CT angiography. To retrospectively evaluate the amount of contrast medium required with 16- and 64-section computed tomography (CT) for a given patient weight to achieve desirable contrast enhancement during pulmonary CT angiography.Institutional review board approval was obtained, and informed consent was not required for this HIPAA-compliant study. Eighty-five patients (35 men, 50 women

2007 Radiology

3002. Supraaortic arteries: contrast-enhanced MR angiography at 3.0 T--highly accelerated parallel acquisition for improved spatial resolution over an extended field of view. (PubMed)

were obtained for this HIPAA-compliant study. Eighty patients (44 men, 36 women; age range, 44-90 years) underwent contrast-enhanced MR angiography of the head and neck at 3.0 T with an eight-channel neurovascular array coil. By applying a generalized autocalibrating partially parallel acquisition algorithm with an acceleration factor of four, high-spatial-resolution (0.7 x 0.7 x 0.9 mm = 0.44-mm(3) voxels) three-dimensional contrast-enhanced MR angiography was performed during a 20-second breath

2007 Radiology

3003. Nephrogenic systemic fibrosis: risk factors and incidence estimation. (PubMed)

Nephrogenic systemic fibrosis: risk factors and incidence estimation. To retrospectively review data in 13 patients with biopsy-confirmed nephrogenic systemic fibrosis (NSF), assess the associated risk factors, and report the incidence of NSF at the authors' institution.This HIPAA-compliant study had institutional review board approval; informed consent was waived. Statistical analysis was performed for all available clinical and laboratory data in patients with biopsy-confirmed NSF. The data

2007 Radiology

3004. Blunt splenic trauma: delayed-phase CT for differentiation of active hemorrhage from contained vascular injury in patients. (PubMed)

Blunt splenic trauma: delayed-phase CT for differentiation of active hemorrhage from contained vascular injury in patients. To retrospectively evaluate delayed-phase computed tomography (CT) in the differentiation of active splenic hemorrhage requiring emergent treatment from contained vascular injuries (pseudoaneurysms or arteriovenous fistulas) that can be treated electively or managed conservatively.The institutional review board approved this HIPAA-compliant retrospective study

2007 Radiology

3005. Mammary angiosarcomas: imaging findings in 24 patients. (PubMed)

Mammary angiosarcomas: imaging findings in 24 patients. To retrospectively evaluate the clinical, imaging, and pathologic findings of mammary angiosarcomas in 24 patients.The institutional review board approved this HIPAA-compliant study and waived informed consent. Twenty-four patients with records in the surgical pathology database who had a diagnosis of mammary angiosarcoma (n = 26) and who underwent preoperative imaging with mammography, ultrasonography (US), or magnetic resonance (MR

2007 Radiology

3006. Lytic metastases in thoracolumbar spine: computer-aided detection at CT--preliminary study. (PubMed)

Lytic metastases in thoracolumbar spine: computer-aided detection at CT--preliminary study. To evaluate the sensitivity of a computer-aided detection (CAD) system for detection of lytic thoracolumbar spinal lesions at body CT, with results of manual lesion segmentation as the reference standard.The study was HIPAA compliant and institutional review board approved; the institutional review board waived the need for informed consent. The CAD system segments the spine on CT images and searches

2007 Radiology

3007. Does radiologist recommendation for follow-up with the same imaging modality contribute substantially to high-cost imaging volume? (PubMed)

Does radiologist recommendation for follow-up with the same imaging modality contribute substantially to high-cost imaging volume? To retrospectively measure repeat rates for high-cost imaging studies, determining their causes and trends, and the impact of radiologist recommendations for a repeat examination on imaging volume.This HIPAA-compliant study had institutional review board approval, with waiver of informed consent. Repeat examination was defined as a same-modality examination

2007 Radiology

3008. High-spatial-resolution whole-body MR angiography with high-acceleration parallel acquisition and 32-channel 3.0-T unit: initial experience. (PubMed)

High-spatial-resolution whole-body MR angiography with high-acceleration parallel acquisition and 32-channel 3.0-T unit: initial experience. The purpose of this HIPAA-compliant study was to prospectively evaluate the technical feasibility of a multistation high-spatial-resolution whole-body magnetic resonance (MR) angiography protocol in which high-acceleration parallel imaging (with acceleration factors of three and four) is performed with a 32-channel 3.0-T MR system. After institutional

2007 Radiology

3009. Pulmonary embolism: prognostic CT findings. (PubMed)

in compliance with HIPAA regulations. A total of 1193 patients with CT scans positive for PE from January 1, 1997, to December 31, 2002, who had given authorization for retrospective research were included. Scans were independently reviewed by two observers. CT findings were compared with risk of death by using univariate analysis (chi(2) statistic) and multivariate logistic regression. Interobserver variability (kappa statistic or intraclass correlation coefficient), sensitivity, and specificity of CT

2007 Radiology

3010. Pulmonary arterial hypertension: noninvasive detection with phase-contrast MR imaging. (PubMed)

Pulmonary arterial hypertension: noninvasive detection with phase-contrast MR imaging. To retrospectively identify pulmonary arterial (PA) flow parameters measured with phase-contrast magnetic resonance (MR) imaging that allow noninvasive diagnosis of chronic PA hypertension (PAH).The study was HIPAA compliant and was approved by the institutional review board; a waiver of informed consent was obtained. Fifty-nine patients (49 female patients; mean age, 46 years; range, 16-85 years) known

2007 Radiology

3011. Lower extremity deep venous thrombosis: evaluation with ferumoxytol-enhanced MR imaging and dual-contrast mechanism--preliminary experience. (PubMed)

Lower extremity deep venous thrombosis: evaluation with ferumoxytol-enhanced MR imaging and dual-contrast mechanism--preliminary experience. Institutional review board approval and informed consent were obtained for this HIPAA-compliant study, whose purpose was to prospectively evaluate the use of a dual-contrast mechanism in conjunction with an iron oxide blood pool contrast agent, ferumoxytol, to depict deep venous thrombosis (DVT). Nine patients with lower extremity DVT detected with duplex

2007 Radiology

3012. Digital mammography: effects of reduced radiation dose on diagnostic performance. (PubMed)

Digital mammography: effects of reduced radiation dose on diagnostic performance. To experimentally determine the relationship between radiation dose and observer accuracy in the detection and discrimination of simulated lesions for digital mammography.This HIPAA-compliant study received institutional review board approval; the informed consent requirement was waived. Three hundred normal craniocaudal images were selected from an existing database of digital mammograms. Simulated mammographic

2007 Radiology

3013. Colorectal cancer: screening double-contrast barium enema examination in average-risk adults older than 50 years. (PubMed)

Colorectal cancer: screening double-contrast barium enema examination in average-risk adults older than 50 years. To retrospectively determine the diagnostic yield of double-contrast barium enema examinations performed for colorectal cancer screening of neoplasms 1 cm or larger or advanced neoplastic lesions of any size in average-risk adults older than 50 years.The Institutional Review Board at the affiliated Veterans Affairs Medical Center approved this HIPAA-compliant study protocol and did

2006 Radiology

3014. Mammographic density measured with quantitative computer-aided method: comparison with radiologists' estimates and BI-RADS categories. (PubMed)

Mammographic density measured with quantitative computer-aided method: comparison with radiologists' estimates and BI-RADS categories. To retrospectively compare computer-aided mammographic density estimation (MDEST) with radiologist estimates of percentage density and Breast Imaging Reporting and Data System (BI-RADS) density classification.Institutional Review Board approval was obtained for this HIPAA-compliant study; patient informed consent requirements were waived. A fully automated MDEST

2006 Radiology

3015. Preoperative functional MR imaging localization of language and motor areas: effect on therapeutic decision making in patients with potentially resectable brain tumors. (PubMed)

Preoperative functional MR imaging localization of language and motor areas: effect on therapeutic decision making in patients with potentially resectable brain tumors. To prospectively evaluate the effect of preoperative functional magnetic resonance (MR) imaging localization of language and motor areas on therapeutic decision making in patients with potentially resectable brain tumors.The Institutional Review Board approved this HIPAA-compliant study, and each patient gave written informed

2006 Radiology

3016. Arterial wall imaging: evaluation with 16-section multidetector CT in blood vessel phantoms and ex vivo coronary arteries. (PubMed)

Arterial wall imaging: evaluation with 16-section multidetector CT in blood vessel phantoms and ex vivo coronary arteries. To evaluate the diagnostic performance of 16-section multidetector computed tomography (CT) for assessment of plaques in phantoms and ex vivo coronary arteries, with intravascular ultrasonography (US) and optical coherence tomography (OCT) as reference standards.Research protocol was HIPAA compliant and approved by institutional review board, without informed consent

2006 Radiology

3017. Classification of breast lesions with multimodality computer-aided diagnosis: observer study results on an independent clinical data set. (PubMed)

. The HIPAA-compliant observer study was conducted with five breast radiologists and five breast imaging fellows, all of whom gave confidence ratings and patient management decisions, both without and with the computer aid, for 97 lesions that were unknown to both the observers and the computer. The performance of each observer without and with the computer aid was quantified by using four performance measures: area under the receiver operating characteristic curve (A(z)) value, partial A(z) value

2006 Radiology

3018. MR elastography of the liver: preliminary results. (PubMed)

MR elastography of the liver: preliminary results. To develop a method for measuring liver stiffness with magnetic resonance (MR) elastography and to prospectively test this technique in healthy volunteers and patients with liver fibrosis.This HIPAA-compliant study was approved by an institutional review board, and informed consent was obtained from each subject. First, to determine the feasibility of applying shear waves to the liver, a pneumatic acoustic wave generator was developed

2006 Radiology

3019. Comparison of symptomatic and asymptomatic atherosclerotic carotid plaque features with in vivo MR imaging. (Full text)

Comparison of symptomatic and asymptomatic atherosclerotic carotid plaque features with in vivo MR imaging. To retrospectively determine if in vivo magnetic resonance (MR) imaging can simultaneously depict differences between symptomatic and asymptomatic carotid atherosclerotic plaque.Institutional review board approval and informed consent were obtained for this HIPAA-compliant study. Twenty-three patients (21 men, two women; mean age, 66.1 years +/- 11.0 [standard deviation]) with unilateral

2006 Radiology PubMed

3020. Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates. (PubMed)

review board. Informed consent was obtained from each donor, and HIPAA guidelines were followed for humans. Two paramagnetic myeloperoxidase substrates--that is, gadolinium-5-hydroxytryptamide-tetraazacyclododecane tetraacetic acid (Gd-5-HT-DOTA) and Gd-bis-5-HT-diethylenetriaminepentaacetic acid (Gd-bis-5-HT-DTPA)--were synthesized. Indium 111-labeled bis-5-HT-DTPA was used to determine biodistribution and target localization. A total of 22 mice were used in three models. In the first model, human

2006 Radiology

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