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Green Coffee Extract

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1. Effects of green coffee extract supplementation on anthropometric indices, glycaemic control, blood pressure, lipid profile, insulin resistance and appetite in patients with the metabolic syndrome: a randomised clinical trial. (PubMed)

Effects of green coffee extract supplementation on anthropometric indices, glycaemic control, blood pressure, lipid profile, insulin resistance and appetite in patients with the metabolic syndrome: a randomised clinical trial. This study was conducted to elucidate the effects of decaffeinated green coffee bean extract (GCE) on anthropometric indices, glycaemic control, blood pressure, lipid profile, insulin resistance and appetite in patients with the metabolic syndrome (Mets). Subjects were

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2019 The British journal of nutrition Controlled trial quality: uncertain

2. Coffee polyphenols extracted from green coffee beans improve skin properties and microcirculatory function. (PubMed)

Coffee polyphenols extracted from green coffee beans improve skin properties and microcirculatory function. Coffee polyphenols (CPPs), including chlorogenic acid, exert various physiological activities. The purpose of this study was to investigate the effects of CPPs on skin properties and microcirculatory function in humans. In this double-blind, placebo-controlled study, 49 female subjects with mildly xerotic skin received either a test beverage containing CPPs (270 mg/100 mL/day

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2017 Bioscience, biotechnology, and biochemistry Controlled trial quality: uncertain

3. New fluorescence spectroscopic method for the simultaneous determination of alkaloids in aqueous extract of green coffee beans (PubMed)

New fluorescence spectroscopic method for the simultaneous determination of alkaloids in aqueous extract of green coffee beans There is no fluorescence spectroscopic method for the determination of trigonelline and theobromine in green coffee beans. Therefore, the objective of this study was to develop a new fluorescence spectroscopic method to determine the alkaloids simultaneously in the aqueous extract of green coffee beans.The calibration curves were linear in the range 2-6, 1-6, 1-5 mg/L (...) for caffeine, theobromine and trigonelline, respectively, with R2 ≥ 0.9987. The limit of detection and limit of quantification were 2, 6 and 7 µg/L and 40, 20 and 20 µg/L for caffeine, theobromine and trigonelline, respectively. Caffeine and trigonelline exhibited well separated fluorescence excitation spectra and therefore the two alkaloids were selectively quantified in the aqueous extract of green coffee. While theobromine showed overlapping fluorescence excitation spectra with caffeine and hence

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2018 Chemistry Central journal

4. Effects of Green Coffee Extract Supplementation on Adropin, Irisin, Vaspine,Systemic Inflammation and Oxidative Stress in Breast Cancer Survivors

Effects of Green Coffee Extract Supplementation on Adropin, Irisin, Vaspine,Systemic Inflammation and Oxidative Stress in Breast Cancer Survivors Effects of Green Coffee Extract Supplementation on Adropin, Irisin, Vaspine,Systemic Inflammation and Oxidative Stress in Breast Cancer Survivors - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effects of Green Coffee Extract Supplementation on Adropin, Irisin, Vaspine,Systemic Inflammation and Oxidative Stress in Breast Cancer Survivors The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk

2017 Clinical Trials

5. Effects of Green Coffee Extract Supplementation on Leptin, Ghrelin, Adiponectin,Anthropometric Measurements, Lipid Profile in Breast Cancer Survivors

Effects of Green Coffee Extract Supplementation on Leptin, Ghrelin, Adiponectin,Anthropometric Measurements, Lipid Profile in Breast Cancer Survivors Effects of Green Coffee Extract Supplementation on Leptin, Ghrelin, Adiponectin,Anthropometric Measurements, Lipid Profile in Breast Cancer Survivors - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved (...) Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effects of Green Coffee Extract Supplementation on Leptin, Ghrelin, Adiponectin,Anthropometric Measurements, Lipid Profile in Breast Cancer Survivors The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical

2017 Clinical Trials

6. Green Coffee Extract Supplementation and Oxidative Stress, Systemic and Vascular Inflammation

Green Coffee Extract Supplementation and Oxidative Stress, Systemic and Vascular Inflammation Green Coffee Extract Supplementation and Oxidative Stress, Systemic and Vascular Inflammation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Green Coffee Extract Supplementation and Oxidative Stress, Systemic and Vascular Inflammation The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03265184 Recruitment Status : Completed First Posted : August 29, 2017 Last Update Posted : August 29, 2017 Sponsor: National

2017 Clinical Trials

7. Effect of green coffee extract on rheological, physico-sensory and antioxidant properties of bread (PubMed)

Effect of green coffee extract on rheological, physico-sensory and antioxidant properties of bread Green coffee extract, GCE (Coffee canephora) was used at 1.0, 1.5 and 2.0% levels for making bioactive rich bread. The processed GCE from the green coffee beans had 21.42% gallic acid equivalents (GAE) total polyphenols (TPP), 37.28% chlorogenic acid (CGA) and 92.73% radical scavenging activity (RSA), at 100 ppm concentration of GCE and caffeine content (1.75%). Rheological, physico-sensory (...) and antioxidant properties of GCE incorporated breads were analysed and compared with control bread. The results revealed not much significant change in the rheological characteristics of dough up to 1.5% level; an increase in bread volume; greenness of bread crumb and mostly unchanged textural characteristics of the bread with increased addition of GCE from 0 to 2.0%. Sensory evaluation showed that maximum level of incorporation of GCE without adverse effect on the overall quality of bread (especially taste

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2017 Journal of food science and technology

8. NMR Confirmation and HPLC Quantification of Javamide-I and Javamide-II in Green Coffee Extract Products Available in the Market (PubMed)

NMR Confirmation and HPLC Quantification of Javamide-I and Javamide-II in Green Coffee Extract Products Available in the Market Javamide-I/javamide-II are phenolic amides found in coffee. Recent reports suggested that they may contain several biological activities related to human health. Therefore, there is emergent interest about their quantities in coffee-related products. Green coffee extract is a powder extract made of unroasted green coffee beans, available as a dietary supplement (...) . However, there is little information about the amounts of javamide-I/javamide-II in green coffee extract products in the market. Therefore, in this paper, javamide-I/javamide-II were extracted from green coffee extract products and their identifications were confirmed by NMR. After that, the amounts of javamide-I/javamide-II were individually quantified from seven different green coffee extract samples using the HPLC method coupled to an electrochemical detector. The HPLC method provided accurate

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2017 International Journal of Analytical Chemistry

9. Energy restriction combined with green coffee bean extract affects serum adipocytokines and the body composition in obese women. (PubMed)

Energy restriction combined with green coffee bean extract affects serum adipocytokines and the body composition in obese women. Obesity has become a public health problem and is a cause of some preventable illnesses. Among several methods for treating obesity, the use of food supplements is highly common. A commonly used food supplement is green coffee bean extract. The objective of this study was to evaluate the efficacy of green coffee bean extract combined with an energy-restricted diet (...) on the body composition and serum adipocytokines in obese women.In this randomised clinical trial, 64 obese women aged 20-45 years were selected and divided into two groups: an intervention group (receiving 400 mg green coffee bean extract for 8 weeks) and control group (receiving placebo). All participants were on an energy-restricted diet. The body composition, leptin, adiponectin, lipid profile, free fatty acids (FFAs), and fasting blood sugar were compared between the two groups.We observed

2017 Asia Pacific journal of clinical nutrition Controlled trial quality: uncertain

10. Effect of Green Coffee Bean Extract on Streptococcus mutans Count: A Randomised Control Trial (PubMed)

Effect of Green Coffee Bean Extract on Streptococcus mutans Count: A Randomised Control Trial Mouth rinses have been popularly used as a supplementary oral hygiene aid. A lot of commercially available mouth rinses possess few adverse effects, which has necessitated the search for alternative and herbal mouth rinses.The aim of the study was to assess the effect of rinsing with green coffee bean extract in comparison with chlorhexidine mouthwash and sterile water on salivary Streptococcus mutans (...) count.A randomized parallel controlled clinical trial was planned and 45 subjects aged between 18-22 years were selected. The subjects were divided into three groups (n=15 in each group): Group A: Study group: 2% Green coffee bean extract, Group B: Positive control: 0.2% Chlorhexidine (CHX), Group C: Negative control: Sterile water. Group A subjects rinsed mouth with 5 ml of 2% Green coffee bean extract for one minute. Group B subjects rinsed mouth with 5 ml 0.2% CHX mouthwash for one minute. Group C

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2017 Journal of clinical and diagnostic research : JCDR Controlled trial quality: uncertain

11. Green Coffee Extract and Metabolic Syndrome

Green Coffee Extract and Metabolic Syndrome Green Coffee Extract and Metabolic Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Green Coffee Extract and Metabolic Syndrome The safety and scientific (...) Study Details Study Description Go to Brief Summary: Metabolic syndrome (Mets) is an assemblage of risk factors which can increase the risk of developing type 2 diabetes mellitus and cardiovascular disease. Green coffee extract (GCE) is derived from unroasted coffee beans and has substantial amounts of polyphenols primarily chlorogenic acids (CGA). It has been shown that GCE and CGA can exert a positive influence over Mets components including blood pressure, blood glucose, inflammation, oxidative

2016 Clinical Trials

12. Green Coffee Extract

Green Coffee Extract Green Coffee Extract Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Green Coffee Extract Green Coffee Extract (...) Aka: Green Coffee Extract From Related Chapters II. Components (variable per product, some products are decaffeinated) Stimulant Chlorogenic acid Polyphenol with antioxidant effects III. Indications Promoted and sold as a weight loss drug IV. Efficacy Prescriber's Letter does not recommend as of 2012 due to evidence of effect being too preliminary V. References (2012) Presc Lett 19(9): 50 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search

2018 FP Notebook

13. Safety and Efficacy of Banaba–Moringa oleifera–Green Coffee Bean Extracts and Vitamin D3 in a Sustained Release Weight Management Supplement (PubMed)

Safety and Efficacy of Banaba–Moringa oleifera–Green Coffee Bean Extracts and Vitamin D3 in a Sustained Release Weight Management Supplement This 60-day, 30-subject pilot study examined a novel combination of ingredients in a unique sustained release (Carbopol matrix) tablet consumed twice daily. The product was composed of extracts of banaba leaf, green coffee bean, and Moringa oleifera leaf and vitamin D3. Safety was assessed using a 45-measurement blood chemistry panel, an 86-item self

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2016 Phytotherapy Research

14. Short-term effects of a green coffee extract-, Garcinia c ambogia- and L-carnitine-containing chewing gum on snack intake and appetite regulation. (PubMed)

Short-term effects of a green coffee extract-, Garcinia c ambogia- and L-carnitine-containing chewing gum on snack intake and appetite regulation. Different studies have assessed the influence of chewing gum to aid control of appetite and reduce food intake.The aims of the present study were to evaluate the effects of chewing gum on satiety, food hedonics and snack intake and to explore the potential effects of the combination of Garcinia c ambogia, green coffee extract and L-carnitine

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2016 European journal of nutrition Controlled trial quality: uncertain

15. Polyphenols in Green Tea and Coffee Show Anti-Carious Effects

Polyphenols in Green Tea and Coffee Show Anti-Carious Effects UTCAT2837, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Polyphenols in Green Tea and Coffee Show Anti-Carious Effects Clinical Question In an adult population, will dietary bioflavonoids found in green tea reduce risk of dental caries compared to antioxidant-rich coffee? Clinical Bottom Line Research on bioflavonoid supplementation in vitro has shown (...) adherence of Sreptococcus mutans to the tooth surface. #2) Meckelburg/2014 Deciduous molars from children and saliva taken from middle-aged adults Laboratory study Key results The study revealed the coffee species Coffea canephora had an inhibitory action against dental biofim. "C. canephora caused bacterial lysis and consequent release of calcium into the medium." However, the results indicate that the coffee extract did not show a significant difference compared the negative control, purified water

2015 UTHSCSA Dental School CAT Library

16. Assessment of Anti-cancerous Effect of Green, Roasted and Decaffeinated Coffee on Oral Squamous Cell Carcinoma Cell Line

for eligibility information Ages Eligible for Study: Child, Adult, Older Adult Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: human cell lines only oral squamous cell carcinoma cell line green coffee extract roasted coffee extract decaffeinated coffee extract Exclusion Criteria: - mixed tumors animal cell lines Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study (...) Assessment of Anti-cancerous Effect of Green, Roasted and Decaffeinated Coffee on Oral Squamous Cell Carcinoma Cell Line Assessment of Anti-cancerous Effect of Green, Roasted and Decaffeinated Coffee on Oral Squamous Cell Carcinoma Cell Line - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2018 Clinical Trials

17. A Prospective Randomized, Double‐Blind, Two‐Period Crossover Pharmacokinetic Trial Comparing Green Coffee Bean Extract—A Botanically Sourced Caffeine—With a Synthetic USP Control (PubMed)

crossover study was to determine the comparative pharmacokinetics of CGAs with caffeine (natural extract) with synthetic caffeine (US Pharmacopeia [USP] standard). Sixteen healthy male subjects were randomly assigned to take 1 dose of product 1, 60 mg of botanically sourced caffeine from 480 mg of green coffee bean extract, or product 2, 60 mg of synthetic USP caffeine, with 5 days between. Blood analysis was done to determine the levels of CGA compounds, more specifically 3-, 4-, and 5-caffeoylquinic (...) A Prospective Randomized, Double‐Blind, Two‐Period Crossover Pharmacokinetic Trial Comparing Green Coffee Bean Extract—A Botanically Sourced Caffeine—With a Synthetic USP Control Coffee is a primary dietary source of the chlorogenic acids (CGAs) of phenolic compounds. Coffee contains caffeine and other phytonutrients, including CGAs. Caffeine on its own has been well characterized and descried pharmacokinetically in the literature, less so for CGAs. The purpose of this double-blind

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2018 Clinical pharmacology in drug development Controlled trial quality: uncertain

18. The influence of high-temperature heating on composition and thermo-oxidative stability of the oil extracted from Arabica coffee beans. (PubMed)

The influence of high-temperature heating on composition and thermo-oxidative stability of the oil extracted from Arabica coffee beans. The aim of the present study was to establish the influence of high-temperature heating on the composition and thermal behavior of coffee oils obtained from Arabica green and roasted coffee beans, respectively. Morphological studies performed using scanning electron microscopy revealed the oil bodies uniformly distributed within the cells in both types (...) of coffee beans analyzed. The obtained oils have a fatty acid composition rich in linoleic acid, palmitic acid, oleic acid, stearic acid, arachidic acid and linolenic acid. The total content of saturated fatty acids of investigated oils was 49.38 and 46.55%, the others being unsaturated fatty acids. The thermal behavior and thermo-oxidative stability of coffee oils extracted from green coffee beans and roasted coffee beans, the coffee oil high-temperature heated up to 200 °C, were investigated using

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2018 PLoS ONE

19. Bioavailability of Green Tea and Coffee Polyphenols

Details Study Description Go to Brief Summary: There is little information on the dietary intake, absorption, metabolism and bioavailability (degree to which a substance becomes available to the target tissues upon administration) of polyphenols (natural substances present in a variety of foods) in human participants. This study assessed the bioavailability in healthy participants of polyphenols from 2 supplements containing green tea and green coffee extracts. Eleven participants were recruited (...) and their habitual diet was assessed to estimate polyphenol intake. After completing a 24-hour urine collection, participants were given six green tea extract and three green coffee extract tablets, which they took daily for a period of 8 weeks. No tablets were taken during the last 4 weeks of the study. Further 24-hour urines were collected at 2, 4, 8 and 12 weeks. Participants were required to attend HNR (medical laboratory) the day after each 24hour urine collection. At these visits, they were asked to bring

2017 Clinical Trials

20. Cell-specific and roasting-dependent regulation of the Keap1/Nrf2 pathway by coffee extracts (PubMed)

Cell-specific and roasting-dependent regulation of the Keap1/Nrf2 pathway by coffee extracts Coffee is a popular beverage that contains various bioactive compounds. However, its molecular mechanism of action is not fully elucidated. In this context, two previously characterized coffee extracts, a lightly roasted and the corresponding green one, were investigated for their effect on nuclear factor erythroid 2‑related factor 2 (Nrf2) target gene expression in myoblasts and endothelial cells using (...) quantitative PCR. The tested concentrations were non‑cytotoxic and led to improved redox cell status, as was evident by increased reduced glutathione (GSH) levels. In both cell lines, the roasted extract upregulated gene expression more readily than its green counterpart leading to increased NAD(P)H quinone dehydrogenase 1 and γ‑glutamyl cysteine ligase catalytic subunit, among others. The green extract had a mixed effect on the endothelial cells, while, as regards the myoblasts it caused

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2018 Molecular medicine reports

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