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Gonococcal Conjunctivitis

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1. Gonococcal Conjunctivitis

Gonococcal Conjunctivitis Gonococcal Conjunctivitis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Gonococcal Conjunctivitis (...) Gonococcal Conjunctivitis Aka: Gonococcal Conjunctivitis , Gonorrhea Conjunctivitis , Gonorrheal Conjunctivitis , Hyperacute Bacterial Conjunctivitis From Related Chapters II. Causes III. Signs Profuse purulent exudate ("waterfall of pus") Profound lid edema ation Occurs in newborns within 24-48 hours of birth IV. Management: Newborns ral Measures Frequent saline until no discharge Treat mother and partners for and Treat newborn also for Antibiotic ( ) 25 to 50 mg/kg up to 250 mg IV/IM x1 dose (preferred

2018 FP Notebook

2. Conjunctivitis: Bacterial, Viral and Allergic

– glaucoma Hyper-purulent discharge (copious amounts of thick yellow-green pus) with very rapid onset – gonococcal conjunctivitis Visible corneal haze or opacities – keratitis, iritis, glaucoma Focal rather than diffuse redness Contact lens wearer – higher risk of infection, corneal ulceration 1) Non-pharmacologic Avoid contact lens use until symptoms have resolved Discard any eye drop bottles used during infection No-tears baby shampoo (weak solution with warm water) can be used to cleanse crusts from (...) Conjunctivitis: Bacterial, Viral and Allergic Conjunctivitis: Bacterial, Viral and Allergic - medSask Home - College of Pharmacy and Nutrition - University of Saskatchewan Toggle Menu Search the U of S Search Conjunctivitis: Bacterial, Viral and Allergic Infectious or non-infectious Inflammation of the conjunctiva of one or both eyes The conjunctiva is the translucent covering of the sclera (white area) of the eye (bulbar area) and the undersurface of the eyelids (palpebral area) Infectious

2018 medSask

3. Severe Disseminated Gonococcal Infection with Polyarticular Gout: Two Cases in Older Travelers. (PubMed)

Severe Disseminated Gonococcal Infection with Polyarticular Gout: Two Cases in Older Travelers. Two male travelers with histories of gout and hazardous alcohol consumption, presented with a triad of severe culture-positive disseminated gonococcal infection, crystal-positive polyarticular gout, and gonococcal soft tissue collections, following unprotected sexual contact in The Philippines. Both men initially attributed symptoms to gout, since their usual joints were affected, but clinical (...) deterioration occurred with self-administration of anti-inflammatory agents alone. The clinical courses were severe and protracted, requiring aggressive management of infection with prolonged intravenous antimicrobials and repeated surgery, and prolonged anti-inflammatory agents for gout. Joint symptom onset in each case occurred within a week of sexual exposure in conjunction with hazardous alcohol ingestion. We speculate that acute dissemination of infection to previously damaged joints triggered

2018 American Journal of Tropical Medicine & Hygiene

4. Treatment and Recommendations for Homeless Patients with Chlamydial or Gonococcal Infections

history of mother Ask mother about her sexual behaviors and partner(s) in a nonjudgmental way. ? Access to care Inquire about parental/partner treatment for STIs. ? Prenatal/neonatal care Ask mother how many prenatal care visits she had and where child was delivered. Physical Examination ? Confine interview to history. Defer physical exam; refer to pediatric specialist with expertise in evidentiary and post-assault evaluation. Diagnostic Tests For chlamydial/gonococcal conjunctivitis or pneumonia (...) Treatment and Recommendations for Homeless Patients with Chlamydial or Gonococcal Infections 1 A DAPTING YOUR PR A CTICE Treatment and Recommendations for Homeless Patients with Chlamydial or Gonococcal Infections Chlamydial or Gonococcal Infections 2013 Edition 2 ADAPTING YOUR PRACTICE Treatment and Recommendations for Homeless Patients with Chlamydial or Gonococcal Infections Health Care for the Homeless Clinicians’ Network 2013 Edition 3 All material in this document is in the public domain

2013 National Health Care for the Homeless Council

5. Gonococcal Conjunctivitis

Gonococcal Conjunctivitis Gonococcal Conjunctivitis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Gonococcal Conjunctivitis (...) Gonococcal Conjunctivitis Aka: Gonococcal Conjunctivitis , Gonorrhea Conjunctivitis , Gonorrheal Conjunctivitis , Hyperacute Bacterial Conjunctivitis From Related Chapters II. Causes III. Signs Profuse purulent exudate ("waterfall of pus") Profound lid edema ation Occurs in newborns within 24-48 hours of birth IV. Management: Newborns ral Measures Frequent saline until no discharge Treat mother and partners for and Treat newborn also for Antibiotic ( ) 25 to 50 mg/kg up to 250 mg IV/IM x1 dose (preferred

2015 FP Notebook

6. Moxifloxacin 0.5 % eye drop solution (Vigamox) for bacterial conjunctivitis

or treatment of gonococcical conjunctivitis, including neo- natal gonococcical opthalmia, or for the man- agement of Chlamydia trachomatis. Contact lenses are not recommended when signs or symptoms of bacterial conjunctivitis appear. Use in special situations 1 Pregancy and lactation: can be employed. Liver and renal impairment: no dose adjust- ments required. Children: the safety profile and efficacy of moxifloxacin has not been evaluated in neonates and therefore it should be avoided. Nor has (...) Moxifloxacin 0.5 % eye drop solution (Vigamox) for bacterial conjunctivitis 14/2011 Moxifloxacin 0.5% eye drop solution (Vigamox ® ) for bacterial conjunctivitis Cheaper eye drops are just as useful to us Indications 1 Moxifloxacin eye drops are indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of Corynebacterium spp, Micrococcus luteus, S. aureus, S. epidermidis, S. haemolyticus, S. hominis, S. warneri, S. pneumoniae Mechanism of action and pharmacokinetics

2012 Drug and Therapeutics Bulletin of Navarre (Spain)

7. Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Placebo

seasonal/perennial allergic conjunctivitis) or non-adenoviral ocular infection (example: bacterial, fungal, acanthamoebal, or other parasitic). Note: History or concomitant presence of presumed seasonal or perennial allergic conjunctivitis signs/symptoms is not exclusionary. Neonates or infants (that is (ie,) participants < 12 months of age) who have suspected or confirmed (based on the result of any test conducted prior to screening) conjunctivitis of gonococcal, chlamydial, herpetic or chemical (...) Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Placebo Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Placebo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Treatment

2016 Clinical Trials

8. Treatment of Bacterial Conjunctivitis With SHP640 Compared to PVP-Iodine and Placebo

conjunctivitis (except presumed seasonal/perennial allergic conjunctivitis) or non-bacterial ocular infection (eg, viral, fungal, acanthamoebal, or other parasitic). Note: history or concomitant presence of presumed seasonal or perennial allergic conjunctivitis signs/symptoms is not exclusionary. Neonates or infants (ie, subjects less than 12 months of age) who have suspected or confirmed (based on the result of any test conducted prior to screening) conjunctivitis of gonococcal, chlamydial, herpetic (...) Treatment of Bacterial Conjunctivitis With SHP640 Compared to PVP-Iodine and Placebo Treatment of Bacterial Conjunctivitis With SHP640 Compared to PVP-Iodine and Placebo - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2016 Clinical Trials

9. Gonococcal conjunctivitis: accidental infection. (Full text)

Gonococcal conjunctivitis: accidental infection. 974946 1976 12 30 2018 11 13 0008-4409 115 7 1976 Oct 09 Canadian Medical Association journal Can Med Assoc J Gonococcal conjunctivitis: accidental infection. 609, 612 Diena B B BB Wallace R R Ashton F E FE Johnson W W Platenaude B B eng Case Reports Letter Canada Can Med Assoc J 0414110 0008-4409 AIM IM Animals Conjunctivitis etiology Gonorrhea Humans Laboratory Infection Male Mice 1976 10 9 1976 10 9 0 1 1976 10 9 0 0 ppublish 974946 PMC1878787

1976 Canadian Medical Association Journal PubMed

10. Gonococcal Conjunctivitis: A Comparison of Sulfanilamide, Sulfapyridine, and Sulfathiazole in the Treatment of 120 Cases (Full text)

Gonococcal Conjunctivitis: A Comparison of Sulfanilamide, Sulfapyridine, and Sulfathiazole in the Treatment of 120 Cases 16693257 2006 06 01 2008 11 20 0065-9533 39 1941 Transactions of the American Ophthalmological Society Trans Am Ophthalmol Soc Gonococcal Conjunctivitis: A Comparison of Sulfanilamide, Sulfapyridine, and Sulfathiazole in the Treatment of 120 Cases. 322-34 Lewis P M PM eng Journal Article United States Trans Am Ophthalmol Soc 7506106 0065-9533 1941 1 1 0 0 1941 1 1 0 1 1941 1

1941 Transactions of the American Ophthalmological Society PubMed

11. Gonococcal Conjunctivitis Of the Newborn (Full text)

Gonococcal Conjunctivitis Of the Newborn 18730389 2010 06 28 2010 06 28 0008-1264 113 1 1970 Jul California medicine Calif Med Gonococcal conjunctivitis of the newborn. 62 Pearson H E HE eng Journal Article United States Calif Med 0410260 0008-1264 1970 7 1 0 0 1970 7 1 0 1 1970 7 1 0 0 ppublish 18730389 PMC1501210

1970 California Medicine PubMed

12. The value of systematic bacteriologic and microscopic study in the treatment of gonococcal conjunctivitis (Full text)

The value of systematic bacteriologic and microscopic study in the treatment of gonococcal conjunctivitis 16692103 2006 06 01 2008 11 20 0065-9533 11 Pt 2 1907 Transactions of the American Ophthalmological Society Trans Am Ophthalmol Soc The value of systematic bacteriologic and microscopic study in the treatment of gonococcal conjunctivitis. 263-5 Oliver C A CA eng Journal Article United States Trans Am Ophthalmol Soc 7506106 0065-9533 1907 1 1 0 0 1907 1 1 0 1 1907 1 1 0 0 ppublish 16692103

1907 Transactions of the American Ophthalmological Society PubMed

13. GONOCOCCAL CONJUNCTIVITIS IN A SOCKET (Full text)

GONOCOCCAL CONJUNCTIVITIS IN A SOCKET 18168807 2008 01 11 2008 11 20 0007-1161 13 8 1929 Aug The British journal of ophthalmology Br J Ophthalmol GONOCOCCAL CONJUNCTIVITIS IN A SOCKET. 406 Doggart J H JH London. eng Journal Article England Br J Ophthalmol 0421041 0007-1161 1929 8 1 0 0 1929 8 1 0 1 1929 8 1 0 0 ppublish 18168807 PMC512085

1929 The British journal of ophthalmology PubMed

14. Twenty Minutes' talk on Gonococcal Conjunctivitis (Full text)

Twenty Minutes' talk on Gonococcal Conjunctivitis 21773216 2011 11 10 2011 07 20 0007-134X 12 3 1936 Jul The British journal of venereal diseases Br J Vener Dis Twenty Minutes' talk on Gonococcal Conjunctivitis. 202-5 Caddy A A Surgeon Royal Westminster Ophthalmic Hospital. eng Journal Article England Br J Vener Dis 0421042 0007-134X 2011 7 21 6 0 1936 7 1 0 0 1936 7 1 0 1 ppublish 21773216 PMC1053049

1936 British Journal of Venereal Diseases PubMed

15. Update on Treatment Options for Gonococcal Infections. (PubMed)

Update on Treatment Options for Gonococcal Infections. The incidence of Neisseria gonorrhoeae infections in the United States has grown over the past decade. The most recent data provided by the Centers for Disease Control and Prevention (CDC) indicate that reported cases have increased by almost 10% over the last 5 years. In conjunction with this rise, the presence of multidrug-resistant strains of N. gonorrhoeae has also emerged. The 2015 CDC guidelines recommend dual therapy (...) with intramuscular ceftriaxone and oral azithromycin as first-line treatment, although components of this regimen are met with a high level of resistance. Although ceftriaxone resistance has not yet been reported in the United States, it is only a matter of time before such isolates are detected, thus ushering in a new era of difficult-to-manage uncomplicated gonococcal infection. The potential public health crisis and patient-associated sequelae (e.g., pelvic inflammatory disease, epididymitis, and human

2015 Pharmacotherapy

16. Gonococcal Infections (Diagnosis)

the image below. This patient presented with gonococcal urethritis, which became systemically disseminated, leading to gonococcal conjunctivitis of the right eye. Courtesy of the CDC/Joe Miller, VD. See , a Critical Images slideshow, to help make an accurate diagnosis. Signs and symptoms History In women, the major genitourinary symptoms of gonorrhea include the following: Vaginal discharge: The most common presenting symptom of gonorrhea, vaginal discharge from endocervicitis is usually described (...) and often occurs in conjunction with a urethral exudate Urethral strictures: Have become uncommon in the antibiotic era, but they can present with a decreased and abnormal urine stream, as well as with the secondary complications of prostatitis and cystitis Rectal infection: May present with pain, pruritus, discharge, or tenesmus In males and females, the classic presentation of disseminated gonococcal infection (DGI) is an arthritis-dermatitis syndrome. Joint or tendon pain is the most common

2014 eMedicine.com

17. Gonococcal Infections (Overview)

the image below. This patient presented with gonococcal urethritis, which became systemically disseminated, leading to gonococcal conjunctivitis of the right eye. Courtesy of the CDC/Joe Miller, VD. See , a Critical Images slideshow, to help make an accurate diagnosis. Signs and symptoms History In women, the major genitourinary symptoms of gonorrhea include the following: Vaginal discharge: The most common presenting symptom of gonorrhea, vaginal discharge from endocervicitis is usually described (...) and often occurs in conjunction with a urethral exudate Urethral strictures: Have become uncommon in the antibiotic era, but they can present with a decreased and abnormal urine stream, as well as with the secondary complications of prostatitis and cystitis Rectal infection: May present with pain, pruritus, discharge, or tenesmus In males and females, the classic presentation of disseminated gonococcal infection (DGI) is an arthritis-dermatitis syndrome. Joint or tendon pain is the most common

2014 eMedicine.com

18. Gonococcal Infections (Treatment)

by susceptibility testing, after 1-2 days of significant clinical improvement is documented to complete a total course of at least 7 days. [ ] Gonococcal conjunctivitis Treatment recommendations for adults are single doses of ceftriaxone 1 g IM plus azithromycin 1 g PO with saline irrigation. [ , ] Topical antibiotic solutions may also be considered. If the cornea is involved or if corneal involvement cannot be excluded due to lid swelling or chemosis, some physicians treat with a 3-day course of IV antibiotics (...) for patients with severe pelvic inflammatory disease (PID) and for any pregnant patient with an STD Pediatrician - Should be consulted for any child with an STD Ophthalmologist - Should be consulted for every patient with gonococcal conjunctivitis, as this disease may progress rapidly and can cause permanent loss of vision Infectious disease specialist - May be of benefit in cases of disseminated gonococcal infection (DGI) or complicated disease courses In cases of suspected rape or abuse in pediatric

2014 eMedicine.com

19. Gonococcal Infections (Follow-up)

by susceptibility testing, after 1-2 days of significant clinical improvement is documented to complete a total course of at least 7 days. [ ] Gonococcal conjunctivitis Treatment recommendations for adults are single doses of ceftriaxone 1 g IM plus azithromycin 1 g PO with saline irrigation. [ , ] Topical antibiotic solutions may also be considered. If the cornea is involved or if corneal involvement cannot be excluded due to lid swelling or chemosis, some physicians treat with a 3-day course of IV antibiotics (...) for patients with severe pelvic inflammatory disease (PID) and for any pregnant patient with an STD Pediatrician - Should be consulted for any child with an STD Ophthalmologist - Should be consulted for every patient with gonococcal conjunctivitis, as this disease may progress rapidly and can cause permanent loss of vision Infectious disease specialist - May be of benefit in cases of disseminated gonococcal infection (DGI) or complicated disease courses In cases of suspected rape or abuse in pediatric

2014 eMedicine.com

20. Conjunctivitis - allergic

Conjunctivitis - allergic Conjunctivitis - allergic - NICE CKS Clinical Knowledge Summaries Share Conjunctivitis - allergic: Summary Allergic conjunctivitis is a term used to describe a group of ocular conditions associated with an immunoglobulin E (IgE) hypersensitivity reaction including: Seasonal allergic conjunctivitis — occurs periodically and is associated with seasonal allergens (such as tree and grass pollen). Perennial allergic conjunctivitis — associated with non-seasonal (...) environmental allergens often found in the home (such as house dust mites, mould spores or animal dander). Vernal keratoconjunctivitis — commonest and most severe in hot arid environments (such as the Mediterranean, West Africa and India). Atopic keratoconjunctivitis — severe and usually associated with atopic dermatitis of the eyelids. Giant papillary conjunctivitis — also has a mechanical component and can occur as a result of chronic micro-trauma (for example from contact lens wear, ocular prostheses

2012 NICE Clinical Knowledge Summaries

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