How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

7,013 results for

Glucose Tolerance Test 3 hour

by
...
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

141. Diagnostic Accuracies of Glycated Hemoglobin, Fructosamine, and Homeostasis Model Assessment of Insulin Resistance in Predicting Impaired Fasting Glucose, Impaired Glucose Tolerance, or New Onset Diabetes After Transplantation. (Abstract)

Diagnostic Accuracies of Glycated Hemoglobin, Fructosamine, and Homeostasis Model Assessment of Insulin Resistance in Predicting Impaired Fasting Glucose, Impaired Glucose Tolerance, or New Onset Diabetes After Transplantation. New onset diabetes after transplantation (NODAT) is associated with a 3-fold greater risk of cardiovascular disease events, with early identification and treatment potentially attenuating this risk. The optimal screening test to identify those with NODAT remains unclear (...) , and the aim of this study was to examine the diagnostic accuracies of 4 screening tests in identifying impaired fasting glucose, impaired glucose tolerance (IGT), and NODAT.This is a single-center prospective cohort study of 83 nondiabetic kidney transplant recipients between 2008 and 2011. Oral glucose tolerance test was considered the gold standard in identifying IFG/IGT or NODAT. Diagnostic accuracies of random blood glucose, glycated hemoglobin (HBA1c), fructosamine, and Homeostasis Model Assessment

2015 Transplantation

142. Dietary Fatty Acids Differentially Associate with Fasting Versus 2-Hour Glucose Homeostasis: Implications for The Management of Subtypes of Prediabetes Full Text available with Trip Pro

controls (n = 15), athletes (n = 14), and obese (n = 23), as well as people with prediabetes (n = 10) and type 2 diabetes (n = 11), were queried about their habitual diet using a Food Frequency Questionnaire. All subjects were screened by an oral glucose tolerance test (OGTT) and studied using the hyperinsulinemic/euglycemic clamp with infusion of 6,62H2-glucose. Multiple regression was performed to examine relationships between dietary fat intake and 1) fasting plasma glucose, 2) % suppression (...) of endogenous glucose production, 3) 2-hour post-OGTT plasma glucose, and 4) skeletal muscle insulin sensitivity (glucose rate of disappearance (Rd) and non-oxidative glucose disposal (NOGD)). The %kcal from saturated fat (SFA) was positively associated with fasting (β = 0.303, P = 0.018) and 2-hour plasma glucose (β = 0.415, P<0.001), and negatively related to % suppression of hepatic glucose production (β = -0.245, P = 0.049), clamp Rd (β = -0.256, P = 0.001) and NOGD (β = -0.257, P = 0.001). The %kcal

2016 PloS one

143. Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association Full Text available with Trip Pro

or elimination of secondary causes and intensive diet and lifestyle changes are recommended before direct pharmacotherapy. Such changes include weight loss, increased physical activity, limited alcohol consumption, and adoption of various healthy dietary practices such as decreased consumption of refined carbohydrates and simple sugars, substitution of saturated and trans fats with unsaturated fats, and increased consumption of seafood (especially species high in omega-3 fatty acids [n-3 FAs]). The 2002 AHA (...) -intensity statins and niacin also may have substantial triglyceride-lowering effects, which are proportional to baseline triglycerides. Safety and tolerability considerations for these products have been reviewed in detail elsewhere. , Ezetimibe and proprotein convertase subtilisin kexin type 9 monoclonal antibodies have minimal to modest effects and are not indicated for triglyceride lowering. Table 2. Triglyceride-Lowering Efficacy of Non–n-3 FA Agents Drug Approximate Efficacy, % Triglyceride

2019 American Heart Association

144. Relationship Between 1-Hour Glucose Challenge Test Results and Perinatal Outcomes. Full Text available with Trip Pro

Relationship Between 1-Hour Glucose Challenge Test Results and Perinatal Outcomes. To estimate the relationship between 1-hour 50 g glucose challenge test values and perinatal outcomes.This was a secondary analysis of data from a multicenter treatment trial of mild gestational diabetes mellitus. Women with glucose challenge test values of 135-199 mg/dL completed a 3-hour oral glucose tolerance test. Mild gestational diabetes mellitus was defined as fasting glucose less than 95 mg/dL and two (...) or more abnormal oral glucose tolerance test values: 1-hour 180 mg/dL or more; 2-hour 155 mg/dL or more; and 3-hour 140 mg/dL or more. Our study included untreated women with glucose challenge test values of 135-139 mg/dL and 140-199 mg/dL and a comparison group with values less than 120 mg/dL. Primary outcomes included a perinatal composite (stillbirth, neonatal death, hypoglycemia, hyperbilirubinemia, neonatal hyperinsulinemia, and birth trauma), large for gestational age (LGA, birth weight above

2013 Obstetrics and Gynecology

145. Oral Glucose Tolerance Testing After Gestational Diabetes

Oral Glucose Tolerance Testing After Gestational Diabetes Oral Glucose Tolerance Testing After Gestational Diabetes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Oral Glucose Tolerance Testing After (...) or disease Gestational Diabetes Pregnancy Obesity Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 150 participants Observational Model: Cohort Time Perspective: Prospective Official Title: Oral Glucose Tolerance Testing After Gestational Diabetes Study Start Date : October 2012 Actual Primary Completion Date : May 4, 2016 Estimated Study Completion Date : December 31, 2018 Resource links provided by the National Library of Medicine related topics

2014 Clinical Trials

146. Exercise training improves insulin release during glucose tolerance testing in stable chronic heart failure patients. (Abstract)

randomized into training (EX, n = 15) and control (CON, n = 7) groups. Before and after a 12-week training intervention involving endurance and resistance training, glucose tolerance (2-hour oral glucose tolerance test), exercise tolerance (cardiopulmonary exercise test), muscle strength (isokinetic dynamometer), heart function (echocardiography), glycated hemoglobin, body composition (dual-energy x-ray absorptiometry), and quality of life (EQ5D) were assessed.At baseline, glucose levels 2 hours after (...) Exercise training improves insulin release during glucose tolerance testing in stable chronic heart failure patients. Chronic heart failure (CHF) patients often present with (pre)diabetes, which negatively influences prognosis. Unlike the proven effect of exercise on glucose regulation in the general population, its effect in CHF is unclear. Therefore, this study aimed at investigating the effect of exercise training on glucose regulation in stable CHF patients.Twenty-two CHF patients were

2014 Journal of cardiopulmonary rehabilitation and prevention Controlled trial quality: uncertain

147. TNFα dynamics during the oral glucose tolerance test varies according to the level of insulin resistance trimester in pregnant women. Full Text available with Trip Pro

prospectively at 5-16 weeks and 24-28 weeks of pregnancy. Anthropometric measures and blood samples were collected at both visits. A 75-g oral glucose tolerance test (OGTT) was conducted at the second trimester to assess insulin sensitivity status (homeostasis model of assessment of insulin resistance and Matsuda index). TNFα was measured at the first trimester (nonfasting) and at each time point of the OGTT.Participants were 28.4 ± 4.4 years old and had a mean body mass index of 25.5 ± 5.5 kg/m(2) at first (...) TNFα dynamics during the oral glucose tolerance test varies according to the level of insulin resistance trimester in pregnant women. TNFα is suspected to play a role in inflammation and insulin resistance leading to higher risk of metabolic impairment. Controversies exist concerning the role of TNFα in gestational insulin resistance. We investigated the interrelations between TNFα and insulin resistance in a large population-based cohort of pregnant women.Women (n = 756) were followed

2014 Journal of Clinical Endocrinology and Metabolism

148. Clinical Practice Guideline for the Treatment of Intrinsic Circadian Rhythm Sleep-Wake Disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep Wake Rhythm Disorder (N24SWD), and Irregular Sleep-W

). A parallel group design was used to test 28 days of daily evening exposure to a white broad-spectrum light (∼265 lux) versus a dim red light control (∼2 lux) among 47 patients (mean age 70.0 ± 6.4 years). The light source consisted of a rice paper shade over a vertical light tube, and the protocol instructed subjects to sit within 1 meter of the light source, for 2–3 hours in duration, ending 1 hour before habitual bedtime. There were no significant posttreatment group differences with respect to most (...) -Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). An Update for 2015 R. Robert Auger, MD 1 ; Helen J. Burgess, PhD 2 ; Jonathan S. Emens, MD 3 ; Ludmila V. Deriy, PhD 4 ; Sherene M. Thomas, PhD 4 ; Katherine M. Sharkey, MD, PhD 5 1 Mayo Center for Sleep Medicine, Rochester, MN; 2 Rush University Medical Center, Chicago, IL; 3 Portland VA Medical Center, Portland, OR; 4 American

2015 American Academy of Sleep Medicine

149. A Human Clinical Trial Evaluating the Effect of MealShapeâ„¢ on Blood Glucose Level Following Consumption of Standard Meal

blood glucose level > 140 mg/dl during an Oral Glucose Tolerance Test. Subject with any sensitivity or allergy to any of the products used within this clinical trial. Intake of product (food and dietary supplement) having an effect on glycemia and insulinemia. Intake of all chronic medication excepted oestroprogestative or progestative contraception started at least three months preceding the screening visit. Contacts and Locations Go to Information from the National Library of Medicine To learn (...) on biomedical experimentation. Exclusion Criteria: Subject with type 1 or 2 diabetes Smoker. Light smoker (less than 5 cigarettes per day) or former smoker (smoking more than 5 cigarettes per day) having stopped less than three months. Smoking (or use of smoking substitute e.g. nicotine patch) is not permitted from screening throughout the study. Subject with fasting capillary blood glucose level > 110 mg/dl. Subject with fasting capillary blood glucose level ≤ 110 mg/dl and 2 hours postprandial capillary

2014 Clinical Trials

150. Dose Comparisons of Leucine-Metformin Combinations on Blood Glucose Levels In Type 2 Diabetic Patients

changes in baseline-corrected plasma glucose and insulin area under the concentration curves from baseline to day 28 and changes in insulin secretory rates as assessed during a 3-hour meal tolerance test. Finally the effects of gastrointestinal symptoms will be assessed by subject questionnaires. The study will include a total of 3 periods: screening or washout of current diabetic monotherapy, a pre-treatment period to ensure subjects will be compliant, and a treatment period of 4 weeks (...) , with the first dosing of medication on day 1 of the study. Each day blood glucose readings will be measured and recorded by patients. Three-hour standardized meal tests will be performed at Baseline (Day 1) and at Study Termination (Day 28). In addition, two, 7-day continuous glucose assessments will be conducted, as well as two seven point glucose profiles. Patients will also be asked about any gastrointestinal side effects they experience. Study Design Go to Layout table for study information Study Type

2014 Clinical Trials

151. Blood Glucose Variability in Obese Youth Participating in a Lifestyle Modification Program

glucose levels with a glucometer 3 times a day, at least every 12 hours (ideally on waking in the morning before eating, before dinner, and before bedtime), to calibrate the sensor. Subjects will be given a glucometer to obtain fingerstick blood sugar values and receive instruction regarding its use. During the follow up visits the CGM will be removed, and the CGM and glucometer will be downloaded and collected. The food record will be collected. Study Design Go to Layout table for study information (...) the program and reversal of early abnormalities in glucose metabolism. While abnormalities on standardized oral glucose tolerance testing are well described in obese youth, this test may not reflect the "real life" glycemia changes in obese children. Understanding early glycemic changes in obese youth is important to better identify those at risk and strategize effective treatment plans, to avoid progression to prediabetes and diabetes. Thus the use of a continuous glucose monitor (CGM) may be a helpful

2014 Clinical Trials

152. One-hour plasma glucose as a predictor of the development of Type 2 diabetes in Japanese adults. (Abstract)

One-hour plasma glucose as a predictor of the development of Type 2 diabetes in Japanese adults. To test the hypothesis that 1-h plasma glucose in an oral glucose tolerance test is a better predictor of the development of diabetes than 2-h plasma glucose, independently of indices of insulin secretion or action in Japanese adults.A historical cohort study was conducted in 1445 Japanese workers who did not have diabetes. The association between 1-h plasma glucose and the development of Type 2 (...) of 2-h plasma glucose was diminished and was no longer significant after adjustments for 1-h plasma glucose.One-hour plasma glucose had a greater association with the future development of Type 2 diabetes than did 2-h plasma glucose, independently of oral glucose tolerance test-derived indices of insulin action in a Japanese population.© 2015 Diabetes UK.

2015 Diabetic Medicine

153. One-hour post-load hyperglycemia is a stronger predictor of type 2 diabetes than impaired fasting glucose. Full Text available with Trip Pro

One-hour post-load hyperglycemia is a stronger predictor of type 2 diabetes than impaired fasting glucose. Subjects with normal glucose tolerance (NGT) but 1-h postload glucose ≥ 155 mg/dL (NGT-1h-high) exhibit an intermediate cardiometabolic risk profile between individuals with NGT and impaired glucose tolerance (IGT).This study aimed to evaluate whether NGT-1h-high subjects have different cardiometabolic characteristics and an increased risk of type 2 diabetes compared with individuals (...) with isolated impaired fasting glucose (IFG).A cross-sectional analysis was performed on 595 nondiabetic subjects who underwent an oral glucose tolerance test and an euglycemic hyperinsulinemic clamp in an ambulatory care setting. In addition, a longitudinal analysis was performed on 392 individuals, who were reexamined after a followup of 5.2 ± 0.9 y.Insulin sensitivity, beta-cell function, and risk of developing diabetes were measured.Subjects with NGT-1h-high have a significant reduction of peripheral

2015 Journal of Clinical Endocrinology and Metabolism

154. Eight Hours of Nightly CPAP Treatment of Obstructive Sleep Apnea Improves Glucose Metabolism in Prediabetes: A Randomized Controlled Trial. Full Text available with Trip Pro

was the overall glucose response as quantified by the area under the curve for glucose during 2-hour oral glucose tolerance testing. Secondary outcomes included fasting and 2-hour glucose and insulin, the area under the curves for insulin and insulin secretion, norepinephrine, insulin sensitivity, acute insulin response to glucose, and 24-hour blood pressure.The overall glucose response was reduced (treatment difference: -1,276.9 [mg/dl] · min [95% confidence interval, -2,392.4 to -161.5]; P = 0.03 (...) parallel group study, 39 participants were randomly assigned to receive either 8-hour nightly CPAP (n = 26) or oral placebo (n = 13). Sleep was polysomnographically recorded in the laboratory on each night. CPAP adherence was ensured by continuous supervision. Participants continued their daily routine activities outside the laboratory. Glucose metabolism was assessed at baseline and after 2 weeks of assigned treatment using both the oral and intravenous glucose tolerance tests. The primary outcome

2015 American Journal of Respiratory and Critical Care Medicine Controlled trial quality: predicted high

155. CRACKCast E126 – Diabetes Mellitus and Disorders of Glucose Homeostasis

. Normally, our body’s glucose is derived from three sources—intestinal absorption from the diet, endogenous production from the breakdown of glycogen (glycogenolysis), and the formation of glucose from precursors (gluconeogenesis), including lactate, pyruvate, amino acids, and glycerol. Insulin receptors on the beta cells of the pancreas sense elevations in the blood glucose concentration and trigger insulin release into the blood. It sticks around for 3-10 minutes before it is broken down in the liver (...) in a severely acidemic patient, we do not recommend routine bicarbonate administration. [3] What is euglycemic DKA? Answer: Euglycemic DKA (blood glucose level ≤ 16.6 (300 mg/dL)) This phenomenon has been reported in up to 18% of patients. Categories of oral agents may be divided into those that increase the insulin supply, including sulfonylureas, secretagogues, and insulin itself. Medications that decrease insulin resistance include the biguanides and thiazolidinediones; drugs that reduce the rate

2017 CandiEM

156. Prednisone affects inflammation, glucose tolerance, and bone turnover within hours of treatment in healthy individuals. Full Text available with Trip Pro

hypersensitivity, patients received placebo or prednisone 10, 25 or 60 mg daily for 7 days.Effects on peripheral white blood cell (WBC) count, ex vivo whole blood lipopolysaccharide (LPS)-stimulated TNF-α release and response to cutaneous allergen challenge were assessed concurrently with biomarkers for glucose tolerance and bone turnover.Differential peripheral WBC counts changed significantly within hours of prednisone administration. Ex vivo, LPS-stimulated TNF-α was significantly reduced by all prednisone (...) Prednisone affects inflammation, glucose tolerance, and bone turnover within hours of treatment in healthy individuals. Use of glucocorticoids for anti-inflammatory efficacy is limited by their side effects. This study examined, in the same individuals, prednisone's acute, dose-dependent effects on inflammation as well as biomarkers of glucose regulation and bone homeostasis.In this randomized, double-blind, parallel-design trial of healthy adults demonstrating cutaneous allergen-induced

2012 European journal of endocrinology / European Federation of Endocrine Societies Controlled trial quality: uncertain

157. Bone Turnover Markers in Patients with Non-Alcoholic Fatty Liver Disease and/or Type 2 Diabetes during Oral Glucose and Isoglycemic iv Glucose. Full Text available with Trip Pro

is uncertain but may involve the gut-bone axis.We investigated the influence of the gut on glucose-induced changes in plasma bone turnover markers in healthy controls and patients with T2D and/or biopsy-verified NAFLD.Cross-sectional cohort study.Patients with NAFLD with normal glucose tolerance, patients with NAFLD and T2D, patients with T2D without liver disease, and healthy controls.Four-hour 50-g oral glucose tolerance test (OGTT) and an isoglycemic intravenous glucose infusion (IIGI).Collagen type 1 C (...) Bone Turnover Markers in Patients with Non-Alcoholic Fatty Liver Disease and/or Type 2 Diabetes during Oral Glucose and Isoglycemic iv Glucose. Nonalcoholic fatty liver disease (NAFLD) is associated with type 2 diabetes (T2D) and vice versa, and both conditions are associated with an increased risk of fractures and altered bone turnover. Although patients with NAFLD typically suffer from decreased bone mineral density (BMD), T2D is associated with normal to high BMD. The pathophysiology

2018 Journal of Clinical Endocrinology and Metabolism

158. HTA of C-reactive protein point-of-care testing to guide antibiotic prescribing

heterogeneity across trials in the estimated treatment effect. ? Due to limited data, it is unclear what impact CRP POCT testing has on antibiotic prescribing in children. There were no studies that met our inclusion criteria that provided data specifically on patients from long-term care facilities or out-of-hours clinics. As trials were based on short term follow-up data at three months, it is unclear whether clinicians continue to use CRP POCT as a decision support tool over the longer term. ? The use (...) of CRP POCT does not lead to an increase in adverse effects such as mortality, hospitalisations, or reconsultations. There was limited evidence regarding other outcomes of clinical effectiveness and safety. ? CRP POCT devices generally demonstrate acceptable analytical performance in a laboratory setting. When used at the point of care, however, the accuracy and precision of the devices was more variable. The overall time taken for the test to be completed ranges from just over 3 minutes to over 13

2019 Health Information and Quality Authority

159. The Collaborative Assessment, OTCA12, on “C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections (RTIs)

was presented. Planned subgroup analysis (children, older adults [=65 years of age] patients attending out-of-hours (OOH) services and those in long-term care (LTC) facilities) were not possible due to limited data. Only one study included children (aged 3 months to 15 years) and no study specifically reported on CRP testing in older adults. Therefore no conclusions can be drawn on the diagnostic test accuracy of CRP testing in these subgroups and instead, results should be interpreted in terms (...) The Collaborative Assessment, OTCA12, on “C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections (RTIs) Dec2015 © EUnetHTA, 2015. Reproduction is authorised provided EUnetHTA is explicitly acknowledged 1 EUnetHTA Joint Action 3 WP4 Version 1.4, +31 January 2019] Rapid assessment of other technologies using the HTA Core Model ® for Rapid Relative Effectiveness Assessment C-REACTIVE PROTEIN POINT-OF-CARE

2019 EUnetHTA

160. Influence of breastfeeding during the postpartum oral glucose tolerance test on plasma glucose and insulin. Full Text available with Trip Pro

Influence of breastfeeding during the postpartum oral glucose tolerance test on plasma glucose and insulin. To examine the effect of breastfeeding during the postpartum oral glucose tolerance test (OGTT) on maternal blood glucose and insulin among women with recent gestational diabetes mellitus.Participants were enrolled in the Study of Women, Infant Feeding, and Type 2 Diabetes, a prospective observational cohort study of 1,035 Kaiser Permanente Northern California members who had been (...) ) duration of breastfeeding during the OGTT was 15.3 (8.1) minutes. Compared with not having breastfed during the OGTT, having breastfed during the test was associated with lower adjusted mean (95% confidence interval) 2-hour glucose (mg/dL) by -6.2 (-11.5 to -1.0; P=.02), 2-hour insulin (microunits/mL) by -15.1 (-26.8 to -3.5; P=.01), and natural log 2-hour insulin by -0.15 (-0.25 to -0.06; P<.01), and with higher insulin sensitivity index0,120 by 0.08 (0.02-0.15; P=.02), but no differences in plasma

2012 Obstetrics and Gynecology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>