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Glucose Tolerance Test 3 hour

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101. Oral Glucose Tolerance Testing After Gestational Diabetes

Oral Glucose Tolerance Testing After Gestational Diabetes Oral Glucose Tolerance Testing After Gestational Diabetes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Oral Glucose Tolerance Testing After (...) or disease Gestational Diabetes Pregnancy Obesity Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 150 participants Observational Model: Cohort Time Perspective: Prospective Official Title: Oral Glucose Tolerance Testing After Gestational Diabetes Study Start Date : October 2012 Actual Primary Completion Date : May 4, 2016 Estimated Study Completion Date : December 31, 2018 Resource links provided by the National Library of Medicine related topics

2014 Clinical Trials

102. Exercise training improves insulin release during glucose tolerance testing in stable chronic heart failure patients. (PubMed)

randomized into training (EX, n = 15) and control (CON, n = 7) groups. Before and after a 12-week training intervention involving endurance and resistance training, glucose tolerance (2-hour oral glucose tolerance test), exercise tolerance (cardiopulmonary exercise test), muscle strength (isokinetic dynamometer), heart function (echocardiography), glycated hemoglobin, body composition (dual-energy x-ray absorptiometry), and quality of life (EQ5D) were assessed.At baseline, glucose levels 2 hours after (...) Exercise training improves insulin release during glucose tolerance testing in stable chronic heart failure patients. Chronic heart failure (CHF) patients often present with (pre)diabetes, which negatively influences prognosis. Unlike the proven effect of exercise on glucose regulation in the general population, its effect in CHF is unclear. Therefore, this study aimed at investigating the effect of exercise training on glucose regulation in stable CHF patients.Twenty-two CHF patients were

2014 Journal of cardiopulmonary rehabilitation and prevention Controlled trial quality: uncertain

103. Effect of an Acute Bout of Kettlebell Exercise on Glucose Tolerance in Sedentary Men: A Preliminary Study (PubMed)

Effect of an Acute Bout of Kettlebell Exercise on Glucose Tolerance in Sedentary Men: A Preliminary Study Impaired glucose tolerance can have significant health consequences. The purposes of this preliminary study were to examine whether a single session of kettlebell exercise improves acute post-exercise glucose tolerance in sedentary individuals, and whether it was as effective as high-intensity interval running. Six sedentary male subjects underwent a two-hour oral glucose tolerance test (...) following three different conditions: 1) control (no exercise); 2) kettlebell exercise (2 sets of 7 exercises, 15 repetitions per exercise with 30 seconds rest between each exercise); or 3) high-intensity interval running (10 one-minute intervals at a workload corresponding to 90% VO2max interspersed with one-minute active recovery periods). Blood glucose and insulin levels were measured before (0 minutes), and 60 and 120 minutes after glucose ingestion. Both kettlebell and high-intensity interval

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2016 International journal of exercise science

104. Effect of Polyherbal Compound for Control of Blood Sugar in Impaired Glucose Tolerance and Diabetes

: Polyherbal capsule coccinia, bougainvillea, catharanthus A unique combination of 3 herbs that lower blood sugars Other Name: Sugar Balance (SB) Placebo Comparator: Placebo Placebo will contain an inert substance Drug: Placebo Similar looking inactive powder Outcome Measures Go to Primary Outcome Measures : Number of diabetes subjects achieving glycemic control [ Time Frame: 6 months ] a 0.5% reduction in baseline A1c and/or fasting plasma glucose below 125 mg/dl or 2 hour postprandial glucose <180 mg/dl (...) -h Post load Glucose ≥140 mg/dL during an Oral Glucose Tolerance Test (OGTT). The test should be performed as described by the World Health Organisation(WHO), using a glucose load containing the equivalent of 75 g anhydrous glucose dissolved in water. OR Glycosylated haemoglobin (A1C) ≥5.7%. The test should be performed in a laboratory using a method that is National Accreditation Board for Testing and Calibration Laboratories certified and standardized. OR In a patient with classic symptoms

2016 Clinical Trials

105. Glucose Tolerance, Meal Timing and MTNR1B

melatonin concentrations results in impaired glucose control and that this effect is stronger in homozygous MTNR1B risk carriers than in non-carriers. To do so we will test glucose tolerance using identical mixed meals under two dinner conditions: a) delayed dinner or Late Eating (LE): starting1 hour before usual bed time, b) advanced dinner or Early Eating (EE): starting 4 hours before habitual bed time, in a randomized, cross-over study design. These findings could support a clinical application (...) of meal timing with endogenous melatonin concentrations Behavioral: Dinner timing Glucose tolerance after a late diner (1 hour before habitual bedtime) differs from early dinner (4 hours before habitual bedtime) due to the concurrence of meal timing with different levels of endogenous melatonin. This effect can be different among risk allele carriers (G) or non-rick allele carriers (C) of the MTNR1B. Experimental: Late Dinner Timing Test the concurrence of meal timing with elevated endogenous

2016 Clinical Trials

106. The Effects of Aspartame on Appetite, Body Composition and Oral Glucose Tolerance

an oral glucose tolerance test at the beginning and end of a 12 week intervention. . Participants will report to the lab weekly for 12 weeks to pick up their next week's intervention products and measurements for body weight, waist circumference, blood pressure and heart rate. They will consume their intervention products daily for 12 weeks. They will record appetite sensations and collect a 24 hour urine sample at weeks 0, 4, 8, and 12. Study Design Go to Layout table for study information Study Type (...) to Primary Outcome Measures : change oral glucose tolerance [ Time Frame: week 0 4 hours ] sample taken at time point 0 change oral glucose tolerance [ Time Frame: week 0 4 hours ] sample taken at time point 15 minutes post glucola change oral glucose tolerance [ Time Frame: week 0 4 hours ] sample taken at time point 30 minutes post glucola change oral glucose tolerance [ Time Frame: week 0 4 hours ] sample taken at time point 60 minutes post glucola change oral glucose tolerance [ Time Frame: week 0 4

2016 Clinical Trials

107. Effect of Gymnema Sylvestre on Patients With Impaired Glucose Tolerance.

Placebo Comparator: Placebo Patients with IGT Drug: Placebo Placebo, 300mg capsules 2 times daily with the first bite of breakfast and dinner Other Name: Calcined Magnesia Outcome Measures Go to Primary Outcome Measures : Fasting plasma glucose [ Time Frame: 90 days ] Before and after intervention by spectrophotometry 2 hour oral glucose tolerance test (2-h OGTT) [ Time Frame: 90 days ] Before and after intervention by spectrophotometry A1C [ Time Frame: 90 days ] Before and after intervention by high (...) Intervention/treatment Phase Impaired Glucose Tolerance Drug: Gymnema Sylvestre Drug: Placebo Phase 2 Detailed Description: The target is to evaluate the effect of the administration of Gymnema Sylvestre on glycemic control, insulin secretion and insulin sensibility on patients with IGT. The investigators will conduct a double-blind trial, randomized, placebo control group, each group 12 female and male patients, between 30 and 59 years old with IGT (2-h values in the oral glucose tolerance test [OGTT

2016 Clinical Trials

108. Effect of Lumacaftor-ivacaftor on Glucose Handling and Tolerance in Cystic Fibrosis Phe508del

glucose tolerance test (OGTT) protocol; and blood work for glucose and insulin at 30, 60, 90 and 120 minutes after the glucose load. This will be scheduled at a time that is convenient to the patient, with an attempt to coordinate with the patient's visit to the CF clinic prior to starting lumacaftor-ivacaftor combination drug. At the 2nd study visit (Visit 2), which will take place 3 months after starting the combination drug, the participant will again come to the Diabetes Center after an overnight (...) A subject is given an oral glucose load and insulin and glucose measurements are taken at specified time periods. Other Name: Oral Glucose tolerance test Outcome Measures Go to Primary Outcome Measures : Change in Fasting Glucose [ Time Frame: 3 months ] This will be compared from baseline to 3 months after starting the medication Change in Fasting Glucose [ Time Frame: 6 months ] This will compare baseline to 6 months after starting the medication Secondary Outcome Measures : Genetic risk score [ Time

2016 Clinical Trials

109. Meta-analysis of glucose tolerance, insulin, and insulin resistance in antipsychotic-naïve patients with nonaffective psychosis. (PubMed)

Meta-analysis of glucose tolerance, insulin, and insulin resistance in antipsychotic-naïve patients with nonaffective psychosis. Some studies have suggested that antipsychotic-naïve patients with nonaffective psychosis (NAP) have glucose intolerance.To conduct a systematic review and meta-analysis of fasting glucose (FG), two hour values in the oral glucose tolerance test (2HG), fasting insulin concentration (INS), and insulin resistance (IR).We identified possibly relevant studies (...) a slight increase in FG, which most of them maintain in the normal range despite a small increase in IR by secreting additional INS. When faced with a physiological challenge such as a glucose tolerance test or antipsychotics, they are no longer able to maintain a normal glucose concentration.Copyright © 2016 Elsevier B.V. All rights reserved.

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2016 Schizophrenia Research

110. Diabetes, glucose tolerance, and the risk of sudden cardiac death. (PubMed)

44 years, 52.6 % male, follow-up duration 35-41 years) was divided into diabetes patients (n = 82), subjects with IGT (n = 3806, plasma glucose ≥9.58 mmol/l in one-hour glucose tolerance test), and controls (n = 6706).Diabetes patients had an increased risk of SCD after adjustment confounders (hazard ratio 2.62, 95 % confidence interval 1.46-4.70, p = 0.001) but risk for non-sudden cardiac death was similarly increased and the proportion of SCD of cardiac deaths was not increased. The SCD risk (...) Diabetes, glucose tolerance, and the risk of sudden cardiac death. Diabetes predisposes to sudden cardiac death (SCD). However, it is uncertain whether greater proportion of cardiac deaths are sudden among diabetes patients than other subjects. It is also unclear whether the risk of SCD is pronounced already early in the course of the disease. The relationship of impaired glucose tolerance (IGT) and SCD is scarcely documented.A general population cohort of 10594 middle-aged subjects (mean age

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2016 BMC Cardiovascular Disorders

111. Mechanisms underlying the pathogenesis of isolated impaired glucose tolerance in humans. (PubMed)

Mechanisms underlying the pathogenesis of isolated impaired glucose tolerance in humans. Prediabetes is a heterogeneous disorder classified on the basis of fasting glucose concentrations and 2-hour glucose tolerance.We sought to determine the relative contributions of insulin secretion and action to the pathogenesis of isolated impaired glucose tolerance (IGT).The study consisted of an oral glucose tolerance test and a euglycemic clamp performed in two cohorts matched for anthropometric (...) characteristics and fasting glucose but discordant for glucose tolerance.An inpatient clinical research unit at an academic medical center.Twenty-five subjects who had normal fasting glucose (NFG) and normal glucose tolerance (NGT) and 19 NFG/IGT subjects participated in this study.Subjects underwent a seven-sample oral glucose tolerance test and a 4-hour euglycemic, hyperinsulinemic clamp on separate occasions. Glucose turnover during the clamp was measured using tracers, and endogenous hormone secretion

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2016 Journal of Clinical Endocrinology and Metabolism

112. Physical Activity is Associated with Glucose Tolerance Independent of Microvascular Function: The Maastricht Study. (PubMed)

Physical Activity is Associated with Glucose Tolerance Independent of Microvascular Function: The Maastricht Study. Moderate-to-vigorous physical activity (MVPA) and physical fitness (PF) are positively associated with glucose tolerance. Such associations may be partly conditioned by microvascular function, which is a common correlate to MVPA, PF, and glucose tolerance. To test this hypothesis, the present study sought to investigate independent associations of MVPA and PF with glucose (...) tolerance and to what extent these associations are mediated by microvascular function. Design, Setting, Participants, and Outcome Measures: Data from The Maastricht Study were used (n = 512 for MVPA and n = 488 for PF analyses; mean age, 59 [SD = 9] y, 52 % men). Glucose tolerance was assessed by 2-hour postload plasma glucose levels (2hPG). The total number of weekly hours of MVPA was estimated with the Community Healthy Activities Model Program for Seniors questionnaire. Walking speed during the 6

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2016 Journal of Clinical Endocrinology and Metabolism

113. Prevalence of impaired glucose tolerance and other types of dysglycaemia among young twins and singletons in Guinea-Bissau. (PubMed)

and demographic surveillance system site in the capital Bissau. Twins (n = 209) and singletons (n = 182) were recruited from a previously established cohort. Oral glucose tolerance tests (OGTT) were performed, along with anthropometrics and collection of clinical and dietary data.Median age was 16.6 and 14.2 years between twins and singletons, respectively (P = 0.08). Mean birth weight was 2410 vs. 3090 g, respectively (P < 0.001). Twins had higher median fasting- and two hour capillary plasma glucose, 5.4 (...) Prevalence of impaired glucose tolerance and other types of dysglycaemia among young twins and singletons in Guinea-Bissau. Twins may be at increased risk of dysglycaemic disorders due to adverse fetal conditions. Data from Africa regarding this association is limited. We studied impaired glucose tolerance (IGT) and other types of dysglycemia among twins and singletons in Guinea-Bissau.The study was conducted from February 2011 until March 2012 at the Bandim Health Project, a health

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2016 BMC Endocrine Disorders

114. Effect of vitamin D supplementation on oral glucose tolerance in individuals with low vitamin D status and increased risk for developing type 2 diabetes (EVIDENCE): a double-blind, randomized, placebo-controlled clinical trial. (PubMed)

on plasma glucose after a 2 hour-75 g oral glucose tolerance test (2hrPC glucose), insulin sensitivity and β-cell function.A total of 71 participants with serum 25(OH)D ≤65 nmol/L, impaired fasting glucose and elevated glycated hemoglobin were randomly assigned to receive 28 000 IU of vitamin D3 (VitD; n = 35) or placebo (n = 36) in cheese once weekly for 24 weeks. The primary outcome was the change in 2hPC glucose. Secondary outcomes were fasting glucose, fasting and postprandial insulin, indices (...) of insulin sensitivity and β-cell function, glycated hemoglobin and lipid profile. Participants underwent an oral glucose tolerance test to determine 2hPC glucose.Mean baseline serum 25(OH)D was 48.1 and 47.6 nmol/L in the VitD and placebo groups, respectively. Serum 25(OH)D significantly increased to 98.7 nmol/L (51 nmol/L increase; P < .0001) in the VitD group. No significant differences in fasting ( P = .42) or 2hPC glucose ( P = .55) or other indices of glucose metabolism, including β-cell function

2016 obesity & metabolism Controlled trial quality: predicted high

115. Modest Salt Reduction Lowers Blood Pressure and Albumin Excretion in Impaired Glucose Tolerance and Type 2 Diabetes Mellitus: A Randomized Double-Blind Trial. (PubMed)

of salt restriction with salt or placebo tablets, each for 6 weeks, in 46 individuals with diet-controlled type 2 diabetes mellitus or impaired glucose tolerance and untreated normal or high normal blood pressure (BP). From salt to placebo, 24-hour urinary sodium was reduced by 49±9 mmol (2.9 g salt). This reduction in salt intake led to fall in clinic BP from 136/81±2/1 mm Hg to 131/80±2/1 mm Hg, (systolic BP; P<0.01). Mean ambulatory 24-hour BP was reduced by 3/2±1/1 mm Hg (systolic BP, P<0.01 (...) Modest Salt Reduction Lowers Blood Pressure and Albumin Excretion in Impaired Glucose Tolerance and Type 2 Diabetes Mellitus: A Randomized Double-Blind Trial. The role of salt restriction in patients with impaired glucose tolerance and diabetes mellitus is controversial, with a lack of well controlled, longer term, modest salt reduction trials in this group of patients, in spite of the marked increase in cardiovascular risk. We carried out a 12-week randomized double-blind, crossover trial

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2016 Hypertension Controlled trial quality: uncertain

116. Dietary Intervention for Glucose Tolerance In Teens (DIG IT): Protocol of a randomized controlled trial using health coaching to prevent youth-onset type 2 diabetes. (PubMed)

in adolescents with prediabetes. Eligible participants will be randomized to receive 6months of health coaching or a single dietary consultation that is standard-of-care. The primary outcome will be 2-hour oral glucose tolerance test concentration. Secondary outcomes will include measures of glycemia and insulin action as well as dietary, physical activity and sedentary behaviors measured using an electronic food record, and by inclinometer. Data will be collected before and after the intervention (...) Dietary Intervention for Glucose Tolerance In Teens (DIG IT): Protocol of a randomized controlled trial using health coaching to prevent youth-onset type 2 diabetes. Youth-onset type 2 diabetes (T2D) is a disease that is newly emerging and behavioral strategies for its prevention are limited. Interventions that target the lifestyle behaviors of adolescents, to improve poor dietary quality and reduce excessive sedentariness, promise to reduce the risk of developing T2D. Health coaching

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2016 Contemporary clinical trials Controlled trial quality: uncertain

117. Effects of the internal circadian system and circadian misalignment on glucose tolerance in chronic shift workers. (PubMed)

Effects of the internal circadian system and circadian misalignment on glucose tolerance in chronic shift workers. Shift work is a risk factor for diabetes. The separate effects of the endogenous circadian system and circadian misalignment (ie, misalignment between the central circadian pacemaker and 24-hour environmental/behavioral rhythms such as the light/dark and feeding/fasting cycles) on glucose tolerance in shift workers are unknown.The objective of the study was to test the hypothesis (...) that the endogenous circadian system and circadian misalignment separately affect glucose tolerance in shift workers, both independently from behavioral cycle effects.A randomized, crossover study with two 3-day laboratory visits.Center for Clinical Investigation at Brigham and Women's Hospital.Healthy chronic shift workers.The intervention included simulated night work comprised of 12-hour inverted behavioral and environmental cycles (circadian misalignment) or simulated day work (circadian alignment

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2016 Journal of Clinical Endocrinology and Metabolism Controlled trial quality: uncertain

118. Impact of glucose excursion and mean glucose concentration in oral glucose-tolerance test on oxidative stress among Japanese Americans (PubMed)

Impact of glucose excursion and mean glucose concentration in oral glucose-tolerance test on oxidative stress among Japanese Americans To evaluate the impact of glucose excursion (GE) and mean glucose concentration (MGC) on oxidative stress among persons with or without diabetes.We examined 775 Japanese Americans who had normal glucose tolerance (NGT), impaired glucose tolerance, or diabetes according to the 75 g oral glucose-tolerance test, using fasting, 1-hour, and 2-hour glucose data. We (...) ). Association between GE and isoprostane was significant when adjustment was made for age, sex, smoking status, body mass index, C-reactive protein, glucose tolerance status, and homeostatic model assessment (P=0.029), but the association with MGC was not significant.Our results suggest the possibility that GE might result in oxidative stress, and the relationship is stronger than that for MGC.

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2013 Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

119. Five-hour Oral Glucose Tolerance Test in Obese Children (PubMed)

Five-hour Oral Glucose Tolerance Test in Obese Children 5129181 1972 02 25 2018 11 13 1468-2044 46 250 1971 Dec Archives of disease in childhood Arch. Dis. Child. Five-hour oral glucose tolerance test in obese children. 791-4 Court J M JM Dunlop M M Leonard I I Leonard R F RF eng Journal Article England Arch Dis Child 0372434 0003-9888 0 Blood Glucose 0 Fatty Acids, Nonesterified IY9XDZ35W2 Glucose PDC6A3C0OX Glycerol IM Administration, Oral Adolescent Age Factors Blood Glucose analysis Child (...) Child, Preschool Diabetes Mellitus genetics Fasting Fatty Acids, Nonesterified blood Female Glucose Glucose Tolerance Test Glycerol blood Humans Male Obesity diagnosis Time Factors 1971 12 1 1971 12 1 0 1 1971 12 1 0 0 ppublish 5129181 PMC1647907 J Clin Invest. 1965 Dec;44(12):2010-20 5851958 Ann N Y Acad Sci. 1965 Oct 8;131(1):662-72 5217000 Acta Med Scand. 1966 Feb;179(2):221-7 5908977 J Lab Clin Med. 1968 Mar;71(3):368-77 5645883 Clin Chim Acta. 1968 Jul;21(1):127-32 5658943 Diabetes. 1969 Nov;18

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1971 Archives of Disease in Childhood

120. Effect of empagliflozin monotherapy on postprandial glucose and 24-hour glucose variability in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled, 4-week study. (PubMed)

empagliflozin 10 mg (n = 20), empagliflozin 25 mg (n = 19) or placebo (n = 21) once daily as monotherapy for 28 days. A meal tolerance test and continuous glucose monitoring (CGM) for 24 hours were performed at baseline and on days 1 and 28. The primary endpoint was change from baseline in area under the glucose concentration-time curve 3 hours after breakfast (AUC1-4h for PPG) at day 28.Adjusted mean (95%) differences versus placebo in changes from baseline in AUC1-4h for PPG at day 1 were -97.1 (-126.5 (...) Effect of empagliflozin monotherapy on postprandial glucose and 24-hour glucose variability in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled, 4-week study. This study evaluated the effect of empagliflozin on postprandial glucose (PPG) and 24-hour glucose variability in Japanese patients with type 2 diabetes mellitus (T2DM).Patients (N = 60; baseline mean [SD] HbA1c 7.91 [0.80]%; body mass index 24.3 [3.2] kg/m(2)) were randomized to receive

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2015 Cardiovascular diabetology Controlled trial quality: predicted high

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