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Glucose Tolerance Test 3 hour

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81. Clinical Trial of Efficacy and Safety of Subetta in the Treatment of Impaired Glucose Tolerance

the tablets in your mouth, not swallowing, until completely they are dissolved. Outcome Measures Go to Primary Outcome Measures : Change in 2-hour plasma glucose after a 75-g oral glucose tolerance test [ Time Frame: baseline and 12 weeks of treatment ] For oral glucose tolerance testing, the subject is given 75 g of oral glucose and measurement is taken at 2 hours post-glucose ingestion. All measurements are done in a central laboratory. Secondary Outcome Measures : Percentage of patients with 2-hour (...) , Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Outpatients aged 18 to 70 years, inclusive. Impaired glucose tolerance (plasma glucose from 7.8 to 11.0 mmol / L 2 hours after a 75 g oral glucose load when performing an oral glucose tolerance test, while fasting plasma glucose <7.0 mmol / L). HbA1c in the range of 5.7-6.4%. The body mass index is 25.0-39.9 kg / m^2. Consent to use reliable contraceptive methods during the study (for men and women

2018 Clinical Trials

82. Effect of Medicago Sativa on Oral Glucose Tolerance in Healthy Adults

. They will be select from the same neighborhood and socioeconomic status. After a fasting blood sample patients will be assigned at random-order through a closed-envelope selection, to receive one of two possible sequences during which they received either single oral doses of Medicago sativa or homologated placebo in 1,500 mg and were crossover with a difference of at least 7 days washout interval. Thirty minutes after each intervention patients underwent a 75-g oral glucose tolerant test (OGTT). Area under (...) them. ] Glucose concentration after overnight fasting (10 to 12-h) determined by spectrophotometry methods. Expressed in mmol/L. 2 hour oral glucose tolerance test (2h-PG) [ Time Frame: After the acute administration of placebo and Medicago sativa. 15 days wash period between them. ] Glucose concentration after 75-g oral dextrose load, determined by spectrophotometry methods. Expressed in mmol/L First Phase of Insulin Secretion [ Time Frame: After the acute administration of placebo and Medicago

2018 Clinical Trials

83. Hepatic fat and glucose tolerance in women with recent gestational diabetes Full Text available with Trip Pro

and determinants thereof in women with and without recent gestational dysglycemia.Two hundred and fifty-seven women underwent an antepartum oral glucose tolerance test (OGTT), which diagnosed 97 with GDM, 40 with gestational impaired glucose tolerance (GIGT), and 120 with normal glucose tolerance (NGT). At a mean of 4.8 years post partum, they underwent an OGTT (which revealed that 52 had progressed to pre-diabetes/diabetes) and hepatic ultrasound, on which liver fat was graded as none (n=164), mild (n=66 (...) Hepatic fat and glucose tolerance in women with recent gestational diabetes Women with a history of gestational diabetes mellitus (GDM) have an elevated risk of ultimately developing pre-diabetes and diabetes later in life. They also have an increased prevalence of fatty liver, but recent studies have reported conflicting findings on whether hepatic fat affects their risk of pre-diabetes/diabetes. Thus, we sought to evaluate the associations of liver fat with glucose homeostasis

2018 BMJ open diabetes research & care

84. The Effect of a Single Bout of High Intensity Intermittent Exercise on Glucose Tolerance in Non-diabetic Older Adults Full Text available with Trip Pro

, with the response to an oral glucose tolerance test (OGTT) determined <24 hours after. Inflammatory, haematological, and lipid parameters were also assessed the day after each trial. There was an effect of the trials on the insulin response to an OGTT (P=0.047), but not the glucose response. Following an acute bout of HIIT, insulin concentration during an OGTT was elevated at 60 min compared to the control trial (P=0.045), indicating more insulin was secreted, but glucose concentration was unchanged in all (...) The Effect of a Single Bout of High Intensity Intermittent Exercise on Glucose Tolerance in Non-diabetic Older Adults Our aim was to investigate the acute effects of a single bout of high intensity intermittent training (HIIT) on glucose tolerance and other physiological and metabolic markers in non-diabetic older adults. Fourteen healthy older adults (age, 64 ± 2 y; BMI, 25.7 ± 2.8 kg·m-2) performed two acute exercise trials: continuous moderate intensity exercise (MOD) and HIIT

2018 International journal of exercise science

85. The Effect of Cold Exposure on Glucose Tolerance

Party): Maastricht University Study Details Study Description Go to Brief Summary: The purpose of the study is to evaluate the effect of cold exposure on an individual's glucose tolerance. Previous research has already shown that 10 days acclimation to a mild cold environment (14-15°C) can enhance insulin sensitivity. However, the duration in the cold environment was 6 hours per day which may not be practical for everyone. Therefore, the present study will investigate the effect of a shorter (...) : It is anticipated that 32 participants will enrol in the study. Specifically, 16 participants will be healthy individuals and the other 16 will be individuals with impaired fasting glucose (5.6 mM to 6.9 mM) and/or blood glucose values 7.8-11.0 mM 2h after glucose drink consumption during the OGTT in screening. Initially, the study will investigate the effect of the cold exposure on healthy individuals, and then depending on the results in these individuals, the intervention may be tested on participants

2018 Clinical Trials

86. Exogenous Ketones and Glucose Tolerance

and Interventions Go to Arm Intervention/treatment Experimental: Ketone monoester Acute morning dose of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate (0.45 ml/kg body weight) Dietary Supplement: Ketone monoester Acute ingestion of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate prior a 2-hour oral glucose tolerance test. Placebo Comparator: Placebo Acute morning dose of flavour-matched placebo. Dietary Supplement: Placebo Acute ingestion of a taste-matched placebo prior a 2-hour oral glucose tolerance test. Outcome (...) Measures Go to Primary Outcome Measures : Glucose area under the curve [ Time Frame: 2-hour ] Area under the curve for glucose during oral glucose tolerance test Secondary Outcome Measures : Insulin area under the curve [ Time Frame: 2-hour ] Insulin area under the curve during oral glucose tolerance test Free fatty acids area under the curve [ Time Frame: 2-hour ] Non-esterified fatty acids area under the curve during oral glucose tolerance test Caspase-1 activation [ Time Frame: 15 minutes ] Caspase

2018 Clinical Trials

87. Post-Exercise Carbohydrate-Energy Replacement Attenuates Insulin Sensitivity and Glucose Tolerance the Following Morning in Healthy Adults Full Text available with Trip Pro

in a randomized, placebo-controlled, and double-blinded crossover design. A standardized low-carbohydrate evening meal was consumed in both trials before overnight recovery ahead of a two-hour oral glucose tolerance test (OGTT) the following morning to assess glycemic and insulinemic responses to feeding. Compared to the CHO-DEFICIT condition, CHO-REPLACE increased the incremental area under the plasma glucose curve by a mean difference of 68 mmol·L-1 (95% CI: 4 to 132 mmol·L-1; p = 0.040) and decreased (...) the Matsuda insulin sensitivity index by a mean difference of -2 au (95% CI: -1 to -3 au; p = 0.001). This is the first study to demonstrate that post-exercise feeding to replaceme the carbohydrate expended during exercise can attenuate glucose tolerance and insulin sensitivity the following morning. The mechanism through which exercise improves insulin sensitivity is therefore (at least in part) dependent on carbohydrate availability and so the day-to-day metabolic health benefits of exercise might

2018 Nutrients Controlled trial quality: uncertain

88. Intermittent Fasting Improves Glucose Tolerance and Promotes Adipose Tissue Remodeling in Male Mice Fed a High Fat Diet. Full Text available with Trip Pro

Intermittent Fasting Improves Glucose Tolerance and Promotes Adipose Tissue Remodeling in Male Mice Fed a High Fat Diet. Obesity is associated with increased macrophage and extracellular matrix accumulation in adipose tissue, which can be partially reversed following weight loss by daily caloric restriction. This study examined the effects of 8 weeks of intermittent fasting (IF; 24-hour fast on 3 nonconsecutive days per week) in mice fed a chow or high-fat diet (HFD; 43% fat) on markers (...) of adipose tissue inflammation and fibrosis. We found that IF decreased energy intake, body weight, and fat cell size in HFD-fed mice and decreased fat mass and improved glucose tolerance in chow- and HFD-fed mice. IF decreased mRNA levels of macrophage markers (Lgals3, Itgax, Ccl2, and Ccl3) in inguinal and gonadal fat, as well as adipose tissue macrophage numbers in HFD-fed mice only, and altered genes involved in NLRP3 inflammasome pathway in both diet groups. IF increased mRNA levels of matrix

2018 Endocrinology

89. Insulin resistance according to β-cell function in women with polycystic ovary syndrome and normal glucose tolerance. Full Text available with Trip Pro

and normal glucose tolerance. Additionally, we sought to evaluate the usefulness of oral glucose tolerance test (OGTT)-derived IR indices in lean women with PCOS.We recruited 100 women with PCOS and normal glucose tolerance and 100 age- and BMI-matched women as controls. IR and insulin secretory indices, including the homeostasis-model assessment (HOMA)-IR, HOMA-M120, HOMA-F and the Stumvoll index, were calculated from an OGTT. Increased β-cell function was defined as>75th percentile for the HOMA-F (...) Insulin resistance according to β-cell function in women with polycystic ovary syndrome and normal glucose tolerance. Polycystic ovary syndrome (PCOS) is associated with insulin resistance (IR) and compensatory hyperinsulinemia. IR is recognized as a major risk factor for the development of type 2 diabetes mellitus. However, few studies have investigated IR in women with PCOS and normal glucose tolerance. The objective of this study was to evaluate IR and β-cell function in women with PCOS

2017 PLoS ONE

90. Strong Association Between Insulin-Mediated Glucose Uptake and the 2-Hour, Not the Fasting Plasma Glucose Concentration in the Normal Glucose Tolerance Range. Full Text available with Trip Pro

glucose intolerance received a 75-g oral glucose tolerance test and euglycemic hyperinsulinemic clamp. Total glucose disposal (TGD) during the insulin clamp was compared in IFG and NGT individuals and was related to fasting and 2-hour plasma glucose concentrations in each group.TGD varied considerably between NGT and IFG individuals and displayed a strong inverse relationship with the 2-hour plasma glucose (PG; r = 0.40, P < .0001) but not with the fasting PG. When IFG and NGT individuals were (...) Strong Association Between Insulin-Mediated Glucose Uptake and the 2-Hour, Not the Fasting Plasma Glucose Concentration in the Normal Glucose Tolerance Range. The aim of this study was to examine the relationship between whole-body insulin-mediated glucose disposal and the fasting plasma glucose concentration in nondiabetic individuals.Two hundred fifty-three nondiabetic subjects with normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance, and combined

2014 Journal of Clinical Endocrinology and Metabolism

91. A Practical Approach to the Management of Continuous Glucose Monitoring (CGM) / Real-Time Flash Glucose Scanning (FGS) in Type 1 Diabetes Mellitus in Children and Young People Under 18 years

wirelessly to a compatible smart phone. It is FDA approved and CE mark approved in Europe to make treatment decisions upon its results and is a newer version compared to G4. G5 is the first remote glucose monitoring system that is licenced to make dosing decisions from without checking with a finger prick. blood glucose (BG) testing for treatment decisions. FDA approved and CE Marked. in a 24-hour period to capture the complete glycaemic picture. The Reader can store approximately 90-days of glucose (...) if disruptive at school (Grade – Best Practice) Recommendation 21: Expectations between parents and staff at preschool/school need to be clearly agreed to avoid conflict (Grade – Best Practice) CGM / FGS and Driving Current DVLA (Driver and Vehicle Licensing Agency) rules state that patients with diabetes treated with insulin must comply with blood glucose testing no more than 2 hours before the start of the first journey and every 2 hours while driving. Drivers must also undertake regular blood glucose

2018 British Society for Paediatric Endocrinology and Diabetes

92. Diagnostic accuracy of self-administered urine glucose test strips as a diabetes screening tool in a low-resource setting in Cambodia. Full Text available with Trip Pro

of cFBGmeasurement ≥200 mg/dL or venous blood glucose 2 hours after oral glucose tolerance test (OGTT) ≥200 mg/dL.Of the 1289 participants, 234 (18%) had diabetes based on either cFBG measurement (74, 32%) or the OGTT (160, 68%). The urine glucose test strip was 14% sensitive and 99% specific and failed to identify 201 individuals with diabetes while falsely identifying 7 without diabetes. Those missed by the urine glucose test strip had lower venous fasting blood glucose, lower venous blood glucose 2 hours (...) study.Members of the Borey Santepheap Community in Cambodia (Phnom Penh Municipality, District Dangkao, Commune Chom Chao).All households on randomly selected streets were invited to participate, and adults at least 18 years of age living in the study area were eligible for inclusion.The accuracy of self-administered urine glucose test strip positivity, Hemoglobin A1c (HbA1c)>6.5% and capillary fasting blood glucose (cFBG) measurement ≥126 mg/dL were assessed against a composite reference standard

2018 BMJ open

93. Liver Fat and Insulin Sensitivity Define Metabolite Profiles During a Glucose Tolerance Test in Young Adult Twins. Full Text available with Trip Pro

Liver Fat and Insulin Sensitivity Define Metabolite Profiles During a Glucose Tolerance Test in Young Adult Twins. The associations of body mass index (BMI) and liver fat (LF) with circulating prandial metabolomic markers are incompletely understood.We aimed to characterize circulating metabolite excursions during an oral glucose tolerance test (OGTT) and evaluate whether the metabolomic signatures of BMI discordance coassociate with LF content.We measured 80 metabolite parameters by nuclear (...) magnetic resonance, together with glucose and insulin, during a 2-hour OGTT in 64 monozygotic (MZ) and 73 dizygotic (DZ) twin pairs (aged 22.8 to 36.2 years). Metabolite excursions during the OGTT were compared within BMI-discordant (intrapair difference, BMI ≥ 3 kg/m2) cotwins separately within MZ and DZ pairs. Insulin-based indices were calculated from the OGTT. LF was measured by magnetic resonance spectroscopy in 25 BMI-discordant MZ pairs. Metabolite profiles were compared with respect to LF

2016 Journal of Clinical Endocrinology and Metabolism

94. Oral Glucose Tolerance Testing identifies HIV+ infected women with Diabetes Mellitus (DM) not captured by standard DM definition Full Text available with Trip Pro

Oral Glucose Tolerance Testing identifies HIV+ infected women with Diabetes Mellitus (DM) not captured by standard DM definition HIV-infected (HIV+) individuals may have differential risk of diabetes mellitus (DM) compared to the general population, and the optimal diagnostic algorithm for DM in HIV+ persons remains unclear. We aimed to assess the utility of oral glucose tolerance testing (OGTT) for DM diagnosis in a cohort of women with or at risk for HIV infection.Using American Diabetic (...) Association DM definitions, DM prevalence and incidence were assessed among women enrolled in the Women's Interagency HIV Study. DM was defined by 2-hour OGTT ≥ 200 mg/dL (DM_OGTT) or a clinical definition (DM_C) that included any of the following: (i) anti-diabetic medication use or self-reported DM confirmed by either fasting glucose (FG) ≥126 mg/dL or HbA1c ≥ 6.5%, (ii) FG ≥ 126 mg/dL confirmed by a second FG ≥ 126 mg/dL or HbA1c 6.5%, or (iii) HbA1c 6.5% confirmed by FG ≥ 126 mg/dL cohort.Overall, 390

2016 Journal of AIDS & clinical research

95. Delphinidin-Rich Maqui Berry Extract (Delphinol®) Lowers Fasting and Postprandial Glycemia and Insulinemia in Prediabetic Individuals during Oral Glucose Tolerance Tests Full Text available with Trip Pro

Delphinidin-Rich Maqui Berry Extract (Delphinol®) Lowers Fasting and Postprandial Glycemia and Insulinemia in Prediabetic Individuals during Oral Glucose Tolerance Tests Delphinidin anthocyanins have previously been associated with the inhibition of glucose absorption. Blood glucose lowering effects have been ascribed to maqui berry (Aristotelia chilensis) extracts in humans after boiled rice consumption. In this study, we aimed to explore whether a standardized delphinidin-rich extract from (...) maqui berry (Delphinol) affects glucose metabolism in prediabetic humans based on glycemia and insulinemia curves obtained from an oral glucose tolerance test (OGTT) after a challenge with pure glucose. Volunteers underwent four consecutive OGTTs with at least one week washout period, in which different doses of Delphinol were administered one hour before glucose intake. Delphinol significantly and dose-dependently lowered basal glycemia and insulinemia. Lower doses delayed postprandial glycemic

2016 BioMed research international

96. Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance Test

the control group included all other women who delivered in the same period. Outcome Measures Go to Primary Outcome Measures : To determine serum glucose levels in both groups during 75 gram oral glucose tolerance test screening [ Time Frame: 3 months ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about (...) Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance Test Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance Test - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Hyperemesis Gravidarum and 75

2016 Clinical Trials

97. Gestational diabetes alters the fetal heart rate variability during an oral glucose tolerance test: a fetal magnetocardiography study. Full Text available with Trip Pro

Gestational diabetes alters the fetal heart rate variability during an oral glucose tolerance test: a fetal magnetocardiography study. Gestational diabetes mellitus (GDM) potentially harms the child before birth. We previously found GDM to be associated with developmental changes in the central nervous system. We now hypothesise that GDM may also impact on the fetal autonomic nervous system under metabolic stress like an oral glucose tolerance test (OGTT).We measured heart rate variability (HRV (...) ) of mothers and fetuses during a three-point OGTT using fetal magnetocardiography (fMCG).Measurements were performed in the fMEG Centre in Tübingen.After exclusion of 23 participants, 13 pregnant women with GDM and 36 pregnant women with normal glucose tolerance were examined.All women underwent the same examination setting with OGTT during which fMCG was recorded three times.Parameters of heart rate variability were measured.Compared with mothers with normal glucose regulation, mothers with GDM showed

2016 BJOG

98. Glucose Tolerance Test 2 hour

"Glucose Tolerance Test 2 hour." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Measurement of glucose 2 hours after glucose challenge for glucose tolerance test (C0202049) Definition (ALT) Analyzing a client/patient's blood sample to determine his or her blood glucose levels. Use DEABZ in conjunction with DEACS. For additional time, use DEACT. For a 4-hour test, use DEACU or DEACV. Service is billed per test (...) Glucose Tolerance Test 2 hour Glucose Tolerance Test 2 hour Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Glucose Tolerance Test 2

2015 FP Notebook

99. Cassia Cinnamon Supplementation Reduces Peak Blood Glucose Responses but Does Not Improve Insulin Resistance and Sensitivity in Young, Sedentary, Obese Women. (Abstract)

Cassia Cinnamon Supplementation Reduces Peak Blood Glucose Responses but Does Not Improve Insulin Resistance and Sensitivity in Young, Sedentary, Obese Women. Cassia cinnamon has been suggested to lower blood glucose (BG) and serum insulin (SI) due to an improvement in insulin resistance (IR) and sensitivity (IS). This study compared the effects Cassia cinnamon had on calculated IR and IS values and BG and SI in response to an oral glucose tolerance test (OGTT) in young, sedentary, and obese (...) women. On three separate days, 10 women had a fasted venous blood sample obtained. Participants were given 5 g of encapsulated placebo (PLC) or 5 g of encapsulated Cassia cinnamon bark (CASS). Three hours after the initial blood sample, another blood sample was obtained to calculate values for IS and IR. The participants then completed an OGTT by consuming a 75 g glucose solution. Blood was obtained 30, 60, 90, and 120 min following glucose ingestion. IS and IR were not significantly different

2016 Journal of dietary supplements Controlled trial quality: uncertain

100. Toothbrushing, Blood Glucose and HbA1c: Findings from a Random Survey in Chinese Population Full Text available with Trip Pro

in Chongqing city, China. Plasma glucose and hemoglobin A1c (HbA1c) were measured, and a 2-hour oral glucose tolerance test was conducted for each respondent. Self-reported toothbrushing frequency was used as a proxy for oral hygiene practice. In a linear model controlling for potential confounders (demographic characteristics, socio-economic status, lifestyle risk factors, BMI, dental visit frequency, etc.), urban residents who barely brushed their teeth had an increase of 0.50 (95% CI: 0.10-0.90) mmol/L (...) Toothbrushing, Blood Glucose and HbA1c: Findings from a Random Survey in Chinese Population Both diabetes and periodontal disease are prevalent in China. Poor oral hygiene practice is the major cause of periodontal disease. An association between oral hygiene practice and blood glucose level was reported in individuals with diabetes, but not in the general population. We examined the association in a population-based random survey recruiting 2,105 adults without previously diagnosed diabetes

2016 Scientific reports

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