How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

7,013 results for

Glucose Tolerance Test 3 hour

by
...
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

181. Dietary Intervention for Glucose Tolerance In Teens (DIG IT): Protocol of a randomized controlled trial using health coaching to prevent youth-onset type 2 diabetes. Full Text available with Trip Pro

in adolescents with prediabetes. Eligible participants will be randomized to receive 6months of health coaching or a single dietary consultation that is standard-of-care. The primary outcome will be 2-hour oral glucose tolerance test concentration. Secondary outcomes will include measures of glycemia and insulin action as well as dietary, physical activity and sedentary behaviors measured using an electronic food record, and by inclinometer. Data will be collected before and after the intervention (...) Dietary Intervention for Glucose Tolerance In Teens (DIG IT): Protocol of a randomized controlled trial using health coaching to prevent youth-onset type 2 diabetes. Youth-onset type 2 diabetes (T2D) is a disease that is newly emerging and behavioral strategies for its prevention are limited. Interventions that target the lifestyle behaviors of adolescents, to improve poor dietary quality and reduce excessive sedentariness, promise to reduce the risk of developing T2D. Health coaching

2016 Contemporary clinical trials Controlled trial quality: uncertain

182. Prevalence of impaired glucose tolerance and other types of dysglycaemia among young twins and singletons in Guinea-Bissau. Full Text available with Trip Pro

and demographic surveillance system site in the capital Bissau. Twins (n = 209) and singletons (n = 182) were recruited from a previously established cohort. Oral glucose tolerance tests (OGTT) were performed, along with anthropometrics and collection of clinical and dietary data.Median age was 16.6 and 14.2 years between twins and singletons, respectively (P = 0.08). Mean birth weight was 2410 vs. 3090 g, respectively (P < 0.001). Twins had higher median fasting- and two hour capillary plasma glucose, 5.4 (...) Prevalence of impaired glucose tolerance and other types of dysglycaemia among young twins and singletons in Guinea-Bissau. Twins may be at increased risk of dysglycaemic disorders due to adverse fetal conditions. Data from Africa regarding this association is limited. We studied impaired glucose tolerance (IGT) and other types of dysglycemia among twins and singletons in Guinea-Bissau.The study was conducted from February 2011 until March 2012 at the Bandim Health Project, a health

2016 BMC Endocrine Disorders

183. Mechanisms underlying the pathogenesis of isolated impaired glucose tolerance in humans. Full Text available with Trip Pro

Mechanisms underlying the pathogenesis of isolated impaired glucose tolerance in humans. Prediabetes is a heterogeneous disorder classified on the basis of fasting glucose concentrations and 2-hour glucose tolerance.We sought to determine the relative contributions of insulin secretion and action to the pathogenesis of isolated impaired glucose tolerance (IGT).The study consisted of an oral glucose tolerance test and a euglycemic clamp performed in two cohorts matched for anthropometric (...) characteristics and fasting glucose but discordant for glucose tolerance.An inpatient clinical research unit at an academic medical center.Twenty-five subjects who had normal fasting glucose (NFG) and normal glucose tolerance (NGT) and 19 NFG/IGT subjects participated in this study.Subjects underwent a seven-sample oral glucose tolerance test and a 4-hour euglycemic, hyperinsulinemic clamp on separate occasions. Glucose turnover during the clamp was measured using tracers, and endogenous hormone secretion

2016 Journal of Clinical Endocrinology and Metabolism

184. Physical Activity is Associated with Glucose Tolerance Independent of Microvascular Function: The Maastricht Study. Full Text available with Trip Pro

Physical Activity is Associated with Glucose Tolerance Independent of Microvascular Function: The Maastricht Study. Moderate-to-vigorous physical activity (MVPA) and physical fitness (PF) are positively associated with glucose tolerance. Such associations may be partly conditioned by microvascular function, which is a common correlate to MVPA, PF, and glucose tolerance. To test this hypothesis, the present study sought to investigate independent associations of MVPA and PF with glucose (...) tolerance and to what extent these associations are mediated by microvascular function. Design, Setting, Participants, and Outcome Measures: Data from The Maastricht Study were used (n = 512 for MVPA and n = 488 for PF analyses; mean age, 59 [SD = 9] y, 52 % men). Glucose tolerance was assessed by 2-hour postload plasma glucose levels (2hPG). The total number of weekly hours of MVPA was estimated with the Community Healthy Activities Model Program for Seniors questionnaire. Walking speed during the 6

2016 Journal of Clinical Endocrinology and Metabolism

185. Characteristics of Glucose Metabolism in Underweight Japanese Women Full Text available with Trip Pro

postmenopausal (50 to 65 years of age) underweight women. We also recruited young normal-weight women (n = 13) and postmenopausal normal-weight women (n = 10) to serve as references. We administered an oral glucose tolerance test (OGTT) and evaluated intramyocellular lipid (IMCL) levels and body composition using 1H-magnetic resonance spectroscopy and dual-energy X-ray absorptiometry, respectively.Young underweight women had similar glucose tolerance as young normal-weight women. However, postmenopausal (...) underweight women had a higher area under the curve (AUC) for glucose during OGTT than postmenopausal normal-weight women. In postmenopausal underweight women, 2-hour glucose levels during OGTT were negatively correlated with lean body mass (r = -0.55, P < 0.01) and insulinogenic index (r = -0.42, P = 0.02) and were positively correlated with IMCL levels (r = 0.40, P = 0.03). Compared with young underweight women, postmenopausal underweight women had a higher AUC for glucose during OGTT and a lower

2018 Journal of the Endocrine Society

186. Omega-3 Polyunsaturated Fatty Acid (Fish Oil) Supplementation and the Prevention of Clinical Cardiovascular Disease Full Text available with Trip Pro

be made for this segment of the population. PREVENTION OF CVD MORTALITY IN DIABETES MELLITUS/PREDIABETES One large RCT (details provided in Table 1) was de- signed to examine the effects of omega-3 PUFA supple- mentation on cardiovascular death among patients with or at risk for diabetes mellitus (based on impaired fast- ing glucose, impaired glucose tolerance). In the ORI- GIN trial (Outcome Reduction With Initial Glargine Inter- vention), the 12 536 patients randomized to omega-3 PUFA supplement (...) %, history of CABG within past 4 y with no intervening CVD event, severe heart failure, or cancer that might affect survival Limitations: high background dietary EPA+DHA intake (median, 210 mg/d) at baseline CABG indicates coronary artery bypass graft surgery; CI, confidence interval; CVD, cardiovascular disease; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; HbA 1c , hemoglobin A 1c ; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; LVH, left ventricular hypertrophy; MI

2017 American Heart Association

187. Coffee Roasting and Glucose Tolerance

a carbohydrate challenge. The aim of this study was to investigate whether two coffee beverages that differ in CGA content due to different roasting degrees will affect glucose regulation differently. In a controlled crossover trial, 11 healthy fasted volunteers consumed 300 mL of either light roasted (LIR) or dark roasted (DAR) coffee, or water, followed 30 min later by a 75-g oral glucose tolerance test (OGTT). Blood samples were drawn at baseline, 30, 60 and 120 min. Differences in glucose and insulin (...) : Chlorogenic acid (CGA) in coffee may lower the postprandial glucose response. CGA is destroyed by dark roasting. In a controlled crossover trial, 11 healthy fasted volunteers consumed 300 mL of either light (LIR) or dark (DAR) roasted coffee, or water, followed 30 min later by a 75-g oral glucose tolerance test (OGTT). Plasma glukose and insulin, appetite, and plasma and urine metabolic profiles will be analysed. The primary aim is to investigate whether roasting affects the postprandial glucose area

2015 Clinical Trials

188. Effects of D-allulose (Psicose) With Sucrose Beverage on Glucose Tolerance and Insulin Level

-response effects of D-allulose (psicose) with sucrose beverage on glucose tolerance [ Time Frame: 2 hours ] oral sucrose tolerance test with sucrose +/- allulose Secondary Outcome Measures : Time to peak plasma glucose concentration [ Time Frame: 2 hours ] oral sucrose tolerance test with sucrose +/- allulose Other Outcome Measures: The dose-response effects of D-allulose with sucrose beverage on insulin levels after oral sucrose tolerance test [ Time Frame: 2 hours ] Oral sucrose tolerance test (...) with sucrose +/- allulose Time to peak plasma insulin concentration [ Time Frame: 2 hours ] Oral sucrose tolerance test with sucrose +/- allulose Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general

2015 Clinical Trials

189. Effect of Smoking on Postprandial Gastric Emptying, Glucose Tolerance and Secretion of Gut and Pancreatic Hormones

. Intervention: Will undergo two separate, identical test days. One absent smoking, and one with concomitant smoking. Dietary Supplement: Liquid mixed meal The subjects will ingest a 400 ml chocolate drink, rich on carbohydrates, fat and lipids. In the following 4 hours, blood samples will be drawn from a PVC for the measurement of plasma glucose, gut- and pancreatic hormones, acetaminophen etc. After the 4 hours, the subjects will be offered an ad libitum meal. Other: Skin Biopsy All subjects will undergo (...) a skin biopsy procedure. Two small (3 mm) biopsies will be taken from the hip area under local anaesthesia. Standard wound treatment will follow. Experimental: Healthy, non-smoking men Twelve healthy, male subjects. Intervention: Will undergo a liquid mixed meal test and a skin biopsy. Dietary Supplement: Liquid mixed meal The subjects will ingest a 400 ml chocolate drink, rich on carbohydrates, fat and lipids. In the following 4 hours, blood samples will be drawn from a PVC for the measurement

2015 Clinical Trials

190. Metformin and sitAgliptin in patients with impAired glucose tolerance and a recent TIA or minor ischemic Stroke (MAAS): study protocol for a randomized controlled trial. Full Text available with Trip Pro

assessment. Non-diabetic patients (n = 100) with a recent (<6 months) TIA, amaurosis fugax or minor ischemic stroke (modified Rankin scale ≤ 3) and impaired glucose tolerance, defined as 2-hour post-load glucose levels between 7.8 and 11.0 mmol/L after repeated standard oral glucose tolerance test, will be included. Patients with renal or liver impairment, heart failure, chronic hypoxic lung disease stage III-IV, history of lactate acidosis or diabetic ketoacidosis, pregnancy or breastfeeding (...) Metformin and sitAgliptin in patients with impAired glucose tolerance and a recent TIA or minor ischemic Stroke (MAAS): study protocol for a randomized controlled trial. Impaired glucose tolerance is present in one third of patients with a TIA or ischemic stroke and is associated with a two-fold risk of recurrent stroke. Metformin improves glucose tolerance, but often leads to side effects. The aim of this study is to explore the feasibility, safety, and effects on glucose metabolism

2015 Trials Controlled trial quality: predicted high

191. Glucose Tolerance in Children With Cystic Fibrosis

between 10-20 years of age with genetically determined cystic fibrosis followed at the university children`s hospital Basel and university children`s hospital Kinderklinik Bern, Switzerland. All patients will get the diagnostics for glucose tolerance with 3 different methods (CGMS, OGTT and optionally IVGTT). Other: Diagnostics for glucose tolerance with 3 different methods. A 7-day course of subcutaneous continuous glucose monitoring system (CGMS). An oral glucose tolerance test done within the 7 day (...) the 7 day course of CGMS ] Standard oral glucose tolerance test. First phase insulin secretion and second phase insulin secretion out of IVGTT (intravenous glucose tolerance test). [ Time Frame: Within the 7 day course of CGMS ] Standard intravenous glucose tolerance test. FEV1% (forced expiratory volume at one second) out of the lung function testing [ Time Frame: Within 3 months of the 7 day course of CGMS ] Lung clearance index [ Time Frame: Within 3 months of the 7 day course of CGMS ] BMI-SDS

2015 Clinical Trials

192. Effect of Chlorogenic Acid on Patients With Impaired Glucose Tolerance

of Chlorogenic Acid on Patients With Impaired Glucose Tolerance The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02621060 Recruitment Status : Unknown Verified December 2015 by Esperanza Martínez-Abundis, University of Guadalajara. Recruitment status was: Recruiting First Posted : December 3, 2015 Last Update (...) and insulin sensitivity. Condition or disease Intervention/treatment Phase Impaired Glucose Tolerance Drug: Placebo Drug: Chlorogenic acid Phase 2 Detailed Description: A randomized, double-blind, placebo-controlled clinical trial was carried out in 30 patients with a diagnosis of impaired glucose tolerance in accordance with the American Diabetes Association criteria. The patients received 400 mg capsules of Chlorogenic acid or placebo, three times daily 1/ 2 hour before meals for 90 days. Before

2015 Clinical Trials

193. Brown Seaweeds Effect on Glucose Tolerance and Appetite Response

Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: BMI 20-25 kg/m2. Waist circumference < 102 cm. Non-smoking. Like (can tolerate) seaweed, pasta, meat sauce as these foods are part of the test meal. Can tolerate paracetamol (Pinex, Actavis, Denmark). Exclusion Criteria: Systemic infections, psychiatric or metabolic diseases, and any clinical condition, chronic or frequent use of medication (including blood thinners, excluding contraceptives), smoking (throughout the trial and 12 months (...) Brown Seaweeds Effect on Glucose Tolerance and Appetite Response Brown Seaweeds Effect on Glucose Tolerance and Appetite Response - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Brown Seaweeds Effect

2015 Clinical Trials

194. Effect of 2-Week Nightly Moderate Hypoxia on Glucose Tolerance in Individuals With Type 2 Diabetes

) simulating an altitude of ~2,400 meters for 7-12 hours each night for a period of 14 days. Baseline testing measures will include a oral glucose tolerance test (OGTT) and body composition (iDXA). Post-treatment testing measures will include OGTT only. Outcome Measures Go to Primary Outcome Measures : Insulin sensitivity via oral glucose tolerance test [ Time Frame: 14 days ] Insulin sensitivity will be estimated by the Matsuda Index (unitless; calculated from the oral glucose tolerance test). Higher (...) values indicate improved insulin sensitivity. Secondary Outcome Measures : Hemoglobin A1c (%) [ Time Frame: 14 days ] Hemoglobin A1c (%) will be measured. Lower values indicate improved fasting glucose levels. 2-hour insulin area-under-the-curve via oral glucose tolerance test [ Time Frame: 14 days ] 2-hour insulin area-under-the-curve (μU/mL x hr) will be estimated from the oral glucose tolerance test 2-hour glucose area-under-the-curve via oral glucose tolerance test [ Time Frame: 14 days ] 2-hour

2015 Clinical Trials

195. Pharmacokinetic and Pharmacodynamic Properties and Tolerability of Single- and multiple-dose Once-daily Empagliflozin, a Sodium Glucose Cotransporter 2 Inhibitor, in Chinese Patients With Type 2 Diabetes Mellitus. (Abstract)

Pharmacokinetic and Pharmacodynamic Properties and Tolerability of Single- and multiple-dose Once-daily Empagliflozin, a Sodium Glucose Cotransporter 2 Inhibitor, in Chinese Patients With Type 2 Diabetes Mellitus. The aim of this study was to investigate the pharmacokinetic and pharmacodynamic properties and tolerability of the oral once-daily sodium glucose cotransporter 2 inhibitor empagliflozin, given in single and multiple 10 and 25 mg doses in Chinese patients with type 2 diabetes mellitus (...) concentrations within 1 to 1.5 hours (median), with plasma levels declining biphasically. Empagliflozin exposure increased roughly dose proportionally between 10 and 25 mg. Mean terminal elimination half-life values at steady state were 13.9 and 12.1 hours with empagliflozin 10 and 25 mg, respectively. Mean (SD) changes from baseline in 24-hour urinary glucose excretion (UGE) on day 1 were +87.7 (22.9) and +82.8 (18.8) g with empagliflozin 10 and 25 mg, respectively, compared with -1.0 (2.8) g with placebo

2015 Clinical therapeutics Controlled trial quality: uncertain

196. To Study the Prevalence of Impaired Glucose Tolerance in Patients with Hepatitis C Virus Related Chronic Liver Disease Full Text available with Trip Pro

a period of one and half year in Dayanand Medical College and Hospital, Ludhiana, Punjab, India.The study was conducted taking total of 100 Hepatitis C virus positive patients above 40 years of age who had fasting blood glucose levels ≥110mg/dl on two occasions, 24 hours apart. These patients underwent an oral glucose tolerance test. Blood sugar levels were tested at 0 and 2 hours. Based on the findings, patients were classified to have impaired glucose tolerance if levels were between 140-200mg/dl (...) /m² v/s 20.13kg/m²). Maximum patients belonged to Child Turcott Pugh class C. Out of 100 patients,80 had cirrhosis on ultrasound. On doing Glucose Tolerance Test, 40 patients were found to have impaired glucose tolerance and one patient to be diabetic. The prevalence increased significantly as age increased and had significant relation with gender. On assessing according to BMI, there was not much significant relation but prevalence was significantly related to severity of disease.

2015 Journal of clinical and diagnostic research : JCDR

197. Association of Gestational Diabetes With Maternal Disorders of Glucose Metabolism and Childhood Adiposity. Full Text available with Trip Pro

with perinatal outcomes and the follow-up study evaluated the long-term outcomes (4697 mothers and 4832 children; study visits occurred between February 13, 2013, and December 13, 2016).Gestational diabetes was defined post hoc using criteria from the International Association of Diabetes and Pregnancy Study Groups consisting of 1 or more of the following 75-g oral glucose tolerance test results (fasting plasma glucose ≥92 mg/dL; 1-hour plasma glucose level ≥180 mg/dL; 2-hour plasma glucose level ≥153 mg/dL (...) ).Primary maternal outcome: a disorder of glucose metabolism (composite of type 2 diabetes or prediabetes). Primary outcome for children: being overweight or obese; secondary outcomes: obesity, body fat percentage, waist circumference, and sum of skinfolds (>85th percentile for latter 3 outcomes).The analytic cohort included 4697 mothers (mean [SD] age, 41.7 [5.7] years) and 4832 children (mean [SD] age, 11.4 [1.2] years; 51.0% male). The median duration of follow-up was 11.4 years. The criteria for GD

2018 JAMA

198. A glycosylated Fc-fused glucagon-like peptide-1 receptor agonist exhibits equivalent glucose lowering to but fewer gastrointestinal side effects than dulaglutide. Full Text available with Trip Pro

as safety variables in rats and monkeys, compared with those of dulaglutide. Glucose reductions in an oral glucose tolerance test were significant at day 3 postdose without severe gastrointestinal adverse events and pulse rate changes in healthy subjects.These results suggest that GLP-1-gFc could be used as a novel GLP-1 receptor agonist with better safety than dulaglutide to maximize therapeutic benefits in subjects with type 2 diabetes.© 2020 The Authors. Diabetes, Obesity and Metabolism published (...) A glycosylated Fc-fused glucagon-like peptide-1 receptor agonist exhibits equivalent glucose lowering to but fewer gastrointestinal side effects than dulaglutide. To evaluate the pharmacokinetic and pharmacodynamic properties of a novel glycosylated Fc-fused glucagon-like peptide-1(GLP-1-gFc) receptor agonist with distinctive receptor binding affinity, designed to improve in vivo stability and safety relative to the commercial GLP-1 analogue dulaglutide, and assess its safety profile

2020 obesity & metabolism

199. Vaccine allergy testing

as the amount of latex in syringes and multidose vials is very low (2). However, if the concern is raised, there is an in vitro test for IgE commercially available. Gelatin testing has been reviewed in prior Ask the Expert questions (3). Gelatin is in a number of vaccines, including mumps/measles/rubella, rabies, living shingles vaccine, varicella, yellow fever and select influenza vaccines (1), and gelatin is animal derived. Some concern has been raised about alpha-galactose-D- galactose allergy (...) and gelatin. A question in the Ask the Expert archives addresses this issue (4). There is commercial testing available for IgE to alpha-gal, but Dr. Cummins feels comfortable with administering vaccine in individuals who can tolerate dairy (4). Quadrivalent papilloma virus and Hepatitis B vaccines may contain residual Saccharomces cerevisiae (baker’s yeast), but sensitivity is not proven to be responsible for reactions (5). Finally, testing with the vaccine itself, recognizing you will not be able

2020 American Academy of Allergy, Asthma & Immunology - Ask the Expert

200. One-Hour Glucose During an Oral Glucose Challenge Prospectively Predicts β-Cell Deterioration and Prediabetes in Obese Hispanic Youth. Full Text available with Trip Pro

One-Hour Glucose During an Oral Glucose Challenge Prospectively Predicts β-Cell Deterioration and Prediabetes in Obese Hispanic Youth. In adults, 1-h glucose during an oral glucose tolerance test (OGTT) predicts the development of type 2 diabetes independent of fasting and 2-h glucose concentrations. The purpose of the current investigation was to examine the utility of elevated 1-h glucose levels to prospectively predict deterioration in β-cell function and the development of prediabetes (...) in high-risk youth.Obese Latino youth with a family history of type 2 diabetes (133 male and 100 female; age 11.1 ± 1.7 years) completed a baseline OGTT and were divided into two groups based upon a 1-h glucose threshold of 155 mg/dL (<155 mg/dL, n = 151, or ≥ 155 mg/dL, n = 82). Youth were followed annually for up to 8 years for assessment of glucose tolerance, body composition by dual-energy X-ray absorptiometry, and insulin sensitivity, insulin secretion, and the disposition index by the frequently

2013 Diabetes Care

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>