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Generalized Anxiety Disorder Scale

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1. The Generalized Anxiety Disorder 7-item (GAD-7) scale in adolescents with generalized anxiety disorder: signal detection and validation (PubMed)

The Generalized Anxiety Disorder 7-item (GAD-7) scale in adolescents with generalized anxiety disorder: signal detection and validation In pediatric patients with anxiety disorders, existing symptom inventories are either not freely available or require extensive time and effort to administer. We sought to evaluate a brief self-report scale-the Generalized Anxiety Disorder 7-item scale (GAD-7)-in adolescents with generalized anxiety disorder (GAD).The Pediatric Anxiety Rating Scale (PARS (...) specificity and sensitivity for detecting moderate and severe anxiety, respectively.The PARS and GAD-7 similarly reflect symptom severity. The GAD-7 is associated with acceptable specificity and sensitivity for detecting clinically significant anxiety symptoms. GAD-7 scores may be used to assess anxiety symptoms and to differentiate between mild and moderate GAD in adolescents, and may be more efficient than the PARS.

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2017 Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists

2. Systematic Review - Relationship of Deployment-related Mild Traumatic Brain Injury to Posttraumatic Stress Disorder, Depressive Disorders, Substance Use Disorders, Suicidal Ideation, and Anxiety Disorders

of evidence Comments PTSD 7 Moderate · Risk of bias for these observational studies was generally moderate · Presence of psychiatric conditions were determined using varying criteria across studies. Severity of TBI was often unspecified (ie, based on ICD-9 codes) · Estimates of the prevalence of mental conditions were consistently higher in Veterans or active duty personnel with history of TBI. Wider variation in estimates observed for depressive, substance use, and anxiety disorders · Wider variation (...) disorders were generally more prevalent in Veterans with a history of mTBI vs no-TBI; one study of Veterans reported similar prevalence of anxiety symptoms across groups (low strength evidence). No studies reported prevalence of anxiety disorders for service members. · The prevalence of PTSD, depressive disorders, substance use disorders, suicidal ideation, and anxiety disorders was primarily determined from diagnostics codes. · Psychiatric condition severity or persistence were rarely reported

2019 Veterans Affairs Evidence-based Synthesis Program Reports

3. Psychometric analysis of the Generalized Anxiety Disorder scale (GAD-7) in primary care using modern item response theory. (PubMed)

Psychometric analysis of the Generalized Anxiety Disorder scale (GAD-7) in primary care using modern item response theory. The Generalized Anxiety Disorder scale (GAD-7) is one of the most frequently used diagnostic self-report scales for screening, diagnosis and severity assessment of anxiety disorder. Its psychometric properties from the view of the Item Response Theory paradigm have rarely been investigated. We aimed to close this gap by analyzing the GAD-7 within a large sample of primary (...) care patients with respect to its psychometric properties and its implications for scoring using Item Response Theory.Robust, nonparametric statistics were used to check unidimensionality of the GAD-7. A graded response model was fitted using a Bayesian approach. The model fit was evaluated using posterior predictive p-values, item information functions were derived and optimal predictions of anxiety were calculated.The sample included N = 3404 primary care patients (60% female; mean age, 52,2

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2017 PLoS ONE

4. Anxiously Awaiting Evidence: Pregabalin in generalized anxiety disorder

Anxiously Awaiting Evidence: Pregabalin in generalized anxiety disorder Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,800 family physicians, family medicine residents, and medical students in Alberta. Established over sixty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care research (...) . www.acfp.ca July 16, 2018 Anxiously Awaiting Evidence: Pregabalin in generalized anxiety disorder Clinical Question: Is pregabalin effective for generalized anxiety disorder (GAD)? Bottom Line: Evidence for pregabalin in GAD is inconsistent and at high-risk of bias (industry-written, short-term, poorly described methods, high drop-outs, and run-in periods that overinflate benefit). If real, an additional one in 6-8 people may respond to pregabalin compared to placebo at 4-8 weeks. However, the change

2018 Tools for Practice

5. Factorial Validity and Invariance of the 7-Item Generalized Anxiety Disorder Scale (GAD-7) Among Populations With and Without Self-Reported Psychiatric Diagnostic Status (PubMed)

Factorial Validity and Invariance of the 7-Item Generalized Anxiety Disorder Scale (GAD-7) Among Populations With and Without Self-Reported Psychiatric Diagnostic Status The 7-item Generalized Anxiety Disorder Scale (GAD-7) is commonly used to monitor anxiety symptoms. However, its factor structure has been inconsistent among competing models: unidimensional, two-dimensional, or higher order models. Additionally, it is unknown whether the scale has measurement invariance between populations (...) with and without self-reported psychiatric diagnostic status. Participants were Japanese adults with self-reported anxiety disorder (AD; n = 479), self-reported AD and major depressive disorder (MDD; n = 314), or without self-reported psychiatric diagnostic status (self-reported non-MDD/AD; n = 654), who completed this questionnaire on the Internet. Confirmatory factor analyses showed the higher order model had similar fit indices to the unidimensional and two-dimensional factor models. For the higher order

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2018 Frontiers in psychology

6. Psychometric Properties of the Generalized Anxiety Disorder Scale-7 (GAD-7) in Outpatients with Anxiety and Mood Disorders (PubMed)

Psychometric Properties of the Generalized Anxiety Disorder Scale-7 (GAD-7) in Outpatients with Anxiety and Mood Disorders 28260835 2018 11 13 0882-2689 39 1 2017 Mar Journal of psychopathology and behavioral assessment J Psychopathol Behav Assess Psychometric Properties of the Generalized Anxiety Disorder Scale-7 (GAD-7) in Outpatients with Anxiety and Mood Disorders. 140-146 10.1007/s10862-016-9571-9 Rutter Lauren A LA Center for Anxiety and Related Disorders, Boston University, 648 Beacon (...) Street, 6 Floor, Boston, MA 02215-2013. Brown Timothy A TA Center for Anxiety and Related Disorders, Boston University, 648 Beacon Street, 6 Floor, Boston, MA 02215-2013. eng R01 MH039096 MH NIMH NIH HHS United States Journal Article 2016 09 10 United States J Psychopathol Behav Assess 8608482 0882-2689 2017 3 7 6 0 2017 3 7 6 0 2017 3 7 6 1 ppublish 28260835 10.1007/s10862-016-9571-9 PMC5333929 NIHMS816011 J Anxiety Disord. 2006;20(8):1016-35 16621437 Med Care. 2008 Mar;46(3):266-74 18388841 Drug

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2016 Journal of psychopathology and behavioral assessment

7. Mindfulness Interventions for the Treatment of Post-Traumatic Stress Disorder, Generalized Anxiety Disorder, Depression, and Substance Use Disorders

reported a greater reduction in BDI-II scores for the mindfulness-based cognitive therapy group than the control group. The improvement of BDI-II scores were maintained at the 3-month follow-up. On the other hand there was no statistical significance for either The Patient Health Questionnaire-9 or Symptom Checklist-90-Revised) depression scales. Mindfulness for PTSD, GAD, Depression, and Substance Use Disorders 10 Generalized anxiety disorder The systematic review by Strauss et al. 20 included one (...) Mindfulness Interventions for the Treatment of Post-Traumatic Stress Disorder, Generalized Anxiety Disorder, Depression, and Substance Use Disorders Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

8. Prevalence and identification of anxiety disorders in pregnancy: the diagnostic accuracy of the two-item Generalised Anxiety Disorder scale (GAD-2). (PubMed)

Prevalence and identification of anxiety disorders in pregnancy: the diagnostic accuracy of the two-item Generalised Anxiety Disorder scale (GAD-2). To estimate the population prevalence of anxiety disorders during pregnancy and investigate the diagnostic accuracy of the two-item Generalised Anxiety Disorder scale (GAD-2) for a) GAD and b) any anxiety disorder.Cross-sectional survey using a stratified sampling design. Sampling weights were used in the analysis to adjust for the bias introduced (...) by the stratified sampling.Inner-city maternity service, South London.545 pregnant women were interviewed after their first antenatal appointment; 528 provided answers on the GAD-2 questions.Diagnosis generated by the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, 4th edition (SCID).Population prevalence of anxiety disorders was 17% (95% CI 12% to 21%): 5% (95% CI 3% to 6%) for GAD, 4% (95% CI 2% to 6%) for social phobia, 8% (95% CI 5% to 11%) for specific phobia and 2

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2018 BMJ open

9. Second Generation Antidepressants for Pediatric patients with Major Depressive Disorder and Anxiety Disorder

Second Generation Antidepressants for Pediatric patients with Major Depressive Disorder and Anxiety Disorder Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time (...) -generation antidepressants for pediatrics. RESEARCH QUESTIONS 1. What is the clinical effectiveness of second-generation antidepressants for the treatment of pediatric patients with major depressive disorder? 2. What is the clinical evidence on the safety of second-generation antidepressants for the treatment of pediatric patients with major depressive disorder? 3. What is the clinical effectiveness of second-generation antidepressants for the treatment of pediatric patients with anxiety disorder? 4

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

10. Yoga for the Treatment of Post-Traumatic Stress Disorder, Generalized Anxiety Disorder, Depression, and Substance Abuse

Yoga for the Treatment of Post-Traumatic Stress Disorder, Generalized Anxiety Disorder, Depression, and Substance Abuse TITLE: Yoga for the Treatment of Post-Traumatic Stress Disorder, Generalized Anxiety Disorder, Depression, and Substance Abuse: A Review of the Clinical Effectiveness and Guidelines DATE: 22 June 2015 CONTEXT AND POLICY ISSUES Post-traumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD), depression and substance abuse (SA) are mental health disorders that can lead (...) of yoga. 11 The purpose of this Rapid Response report is to review the clinical effectiveness of yoga for treating PTSD, GAD, depression and substance abuse, and to summarize the guidelines that are associated with the use of yoga for these conditions. RESEARCH QUESTIONS 1. What is the clinical effectiveness of yoga as an intervention for the treatment of post- traumatic stress disorder, generalized anxiety disorder, depression, and substance abuse? 2. What are the evidence-based guidelines

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

11. Psychometrics of the Screen for Adult Anxiety Related Disorders (SCAARED)- A New Scale for the Assessment of DSM-5 Anxiety Disorders (PubMed)

Psychometrics of the Screen for Adult Anxiety Related Disorders (SCAARED)- A New Scale for the Assessment of DSM-5 Anxiety Disorders To examine the psychometrics of the Screen for Adult Anxiety Related Disorders (SCAARED).The SCAARED was adapted from the Screen for Child Anxiety Related Emotional Disorders. Participants (N=336) ages 18-27 years old were evaluated using the Structured Clinical Interview for DSM-IV Disorders (SCID). The SCAARED was completed at or within two-weeks before the SCID (...) . The psychometrics of the SCAARED were analyzed using standard statistical analyses including principal components, and Receiver Operant Curve analyses. A replication was performed in an age/sex matched independent sample (N=158).The SCAARED showed four factors: somatic/panic/agoraphobia, generalized anxiety, separation anxiety, and social anxiety. The total and each factor scores demonstrated good internal consistency (α=0.86-0.97) and good discriminant validity between anxiety and other disorders and within

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2017 Psychiatry research

12. Screening for depressive and anxiety disorders among adolescents in Indonesia: Formal validation of the centre for epidemiologic studies depression scale - revised and the Kessler psychological distress scale. (PubMed)

, the K6 to detect depressive and anxiety disorders among older adolescents in Indonesia.The empirical psychometric properties were examined formally among students aged 16-18 years attending high schools in Jakarta. The scales were validated against the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-Kid) modules for major depressive episode, dysthymia, panic disorder, separation anxiety disorder, and generalized anxiety disorder.In total, 196 students contributed (...) Screening for depressive and anxiety disorders among adolescents in Indonesia: Formal validation of the centre for epidemiologic studies depression scale - revised and the Kessler psychological distress scale. This study aimed to culturally verify and examine the empirical psychometric properties of the Indonesian versions of the Centre for Epidemiologic Studies Depression Scale - Revised (CESD-R), the Kessler Psychological Distress Scale - 10 items (K10) and a subset of 6 items of the K10

2018 Journal of Affective Disorders

13. Development of the Parent-Rated Anxiety Scale for Youth with Autism Spectrum Disorder. (PubMed)

Development of the Parent-Rated Anxiety Scale for Youth with Autism Spectrum Disorder. Anxiety is common in youth with autism spectrum disorder (ASD). There is no accepted outcome measure for anxiety in this population.Following a series of focus groups with parents of youth with ASD, we generated 72 items (scored 0-3). Parents of 990 youth with ASD (age 5-17; 80.8% male youth) completed an online survey. Factor analysis and item response theory (IRT) analyses reduced the content to a single (...) factor with 25 items. Children with a least mild anxiety (N=116; age 5-17; 79.3% male youth) participated in a comprehensive clinical assessment to evaluate validity and reliability of the 25-item Parent-rated Anxiety Scale for ASD (PRAS-ASD).In the online sample, the mean PRAS-ASD score was 29.04 ± 14.9 (range 0 to 75). Coefficient alpha was 0.93. The IRT results indicated excellent reliability across a wide range of scores with low standard errors. In the clinical sample (N=116), the PRAS-ASD mean

2019 Journal of the American Academy of Child and Adolescent Psychiatry

14. Exercise interventions to reduce anxiety in mid-life and late-life anxiety disorders and sub threshold anxiety disorder- a systematic review and meta-analysis

Exercise interventions to reduce anxiety in mid-life and late-life anxiety disorders and sub threshold anxiety disorder- a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content (...) as assessed by Jablonski scale; continuous; Jablonski score. ">Data to be extracted: secondary outcome(s) Example: 1st author, year of publication, language, journal. ">Data to be extracted: other as well as a to meta-analysis of pre-clinical studies are available. Example: A meta‐analysis will be performed for all outcome measures reported in 10 or more articles. For subgroup analysis a minimum of 8 studies per subgroup is required. If meta‐analysis is not possible, data will be reported through

2019 PROSPERO

15. The efficacy of internet-delivered treatment for generalized anxiety disorder: an updated systematic review and meta-analysis

The efficacy of internet-delivered treatment for generalized anxiety disorder: an updated systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any (...) of reperfusion (if applicable). ">Data to be extracted: animal model Example: Dose, timing of administration, frequency of administration, route of administration, vehicle. ">Data to be extracted: intervention of interest Example: Serum creatinine; continuous; umol/L (may be recalculated from mg/dL). ">Data to be extracted: primary outcome(s) Example: Blood urea nitrogen; continuous; mmol/L (may be recalculated from mg/dL); Renal histological damage as assessed by Jablonski scale; continuous; Jablonski score

2019 PROSPERO

16. The efficacy and safety of repetitive transcranial magnetic stimulation for generalized anxiety disorder: a meta-analysis

The efficacy and safety of repetitive transcranial magnetic stimulation for generalized anxiety disorder: a meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any (...) of reperfusion (if applicable). ">Data to be extracted: animal model Example: Dose, timing of administration, frequency of administration, route of administration, vehicle. ">Data to be extracted: intervention of interest Example: Serum creatinine; continuous; umol/L (may be recalculated from mg/dL). ">Data to be extracted: primary outcome(s) Example: Blood urea nitrogen; continuous; mmol/L (may be recalculated from mg/dL); Renal histological damage as assessed by Jablonski scale; continuous; Jablonski score

2019 PROSPERO

17. Generalized Anxiety Disorder Scale

Generalized Anxiety Disorder Scale Generalized Anxiety Disorder Scale Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Generalized (...) Anxiety Disorder Scale Generalized Anxiety Disorder Scale Aka: Generalized Anxiety Disorder Scale , GAD-7 , GAD-2 II. Indication: Screening and Monitoring III. Scoring: Answers Not at all: 0 Several days: 1 More than half the days: 2 Nearly every day: 3 IV. Questions: Over the past 2 weeks, how often have you been bothered by the following problems Feeling nervous, anxious or on edge Being unable to stop or control worrying Worrying too much about different things Having trouble relaxing Being so

2018 FP Notebook

18. The Validity of the Screen for Child Anxiety Related Emotional Disorders Revised (SCARED-R) Scale and Sub-Scales in Swedish Youth (PubMed)

The Validity of the Screen for Child Anxiety Related Emotional Disorders Revised (SCARED-R) Scale and Sub-Scales in Swedish Youth We evaluated the clinical utility of the Swedish SCARED-R in child- and adolescent psychiatric outpatients (n = 239) and validated it against Longitudinal Expert All Data (LEAD) DSM IV diagnoses based on the Children's Schedule for Affective Disorders and Schizophrenia (KSADS) and subsequent clinical work-up and treatment outcome. The SCARED-R total score (...) and subscales had acceptable sensitivity/specificity for child and parent reports for cut-offs based on Receiver Operating Characteristics (ROC) curves, with mostly moderate area under the curve. Sensitivity ranged from 75% (parent rated social anxiety) to 79% [child rated Generalized Anxiety Disorder (GAD)]. Specificity, ranged from 60% for child-rated GAD to 88% for parent rated social anxiety. Parent-child agreement was moderate, and each informant provided unique information contributing to most

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2017 Child psychiatry and human development

19. The DSM‐5 Dimensional Anxiety Scales in a Dutch non‐clinical sample: psychometric properties including the adult separation anxiety disorder scale (PubMed)

disorders. Participants (285 males, 255 females) completed the DSM-5 Dimensional Anxiety Scales for social anxiety disorder, generalized anxiety disorder, specific phobia, agoraphobia, and panic disorder that were included in previous studies on the scales, and also for separation anxiety disorder, which is included in the DSM-5 chapter on anxiety disorders. Moreover, they completed the Screen for Child Anxiety Related Emotional Disorders Adult version (SCARED-A). The DSM-5 Dimensional Anxiety Scales (...) The DSM‐5 Dimensional Anxiety Scales in a Dutch non‐clinical sample: psychometric properties including the adult separation anxiety disorder scale With DSM-5, the American Psychiatric Association encourages complementing categorical diagnoses with dimensional severity ratings. We therefore examined the psychometric properties of the DSM-5 Dimensional Anxiety Scales, a set of brief dimensional scales that are consistent in content and structure and assess DSM-5-based core features of anxiety

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2016 International journal of methods in psychiatric research

20. Effects of SSRIs on peripheral inflammatory cytokines in patients with Generalized Anxiety Disorder. (PubMed)

, there is no evidence of the similar effects of antidepressants on anxiety. The aim of the study was to investigate the effects of selective serotonin reuptake inhibitors (SSRIs) on peripheral inflammatory cytokines in patients with first episode generalized anxiety disorder (GAD).A prospective cohort design was employed: 42 patients with first episode GAD were treated with either escitalopram or sertraline for 12 weeks. Anxiety was measured by the Generalized Anxiety Disorder Scale and the State Trait Anxiety (...) Effects of SSRIs on peripheral inflammatory cytokines in patients with Generalized Anxiety Disorder. Extensive research into psychoneuroimmunology has led to substantial advances in our understanding of the reciprocal interactions between the central nervous system and the immune system in neuropsychiatric disorders. To date, inflammation has been implicated in the pathogenesis of depression and anxiety. The immunomodulating effects of antidepressants on depression have been reported, however

2019 Brain, behavior, and immunity

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