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12061. Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma

: Treatment Official Title: A Phase I/II Study of Autologous Stem Cell Transplantation Followed by Nonmyeloablative Allogeneic Stem Cell Transplantation for Patients With Relapsed or Refractory Lymphoma - A Multi-center Trial Study Start Date : September 1999 Actual Primary Completion Date : January 2016 Estimated Study Completion Date : September 1, 2019 Resource links provided by the National Library of Medicine related topics: resources: Arms and Interventions Go to Arm Intervention/treatment (...) up to 3 years ] Number of patients surviving without disease by interval. Chemosensitive and chemoresistant subjects will be analyzed separately. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below

2000 Clinical Trials

12062. Worcester Heart Attack Community Surveillance Study

this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: up to 100 Years (Child, Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria No eligibility criteria Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using (...) Medical Publisher's (Book Chapter), Califf R, Wagner G, Mark D, (Eds) p. 548-558, 1988 Gore JM, Goldberg RJ, Alpert JS, Dalen JE: Increased Use of Diagnostic Procedures in Patients with Acute Myocardial Infarction: The Worcester Heart Attack Study. In: Trends in Coronary Heart Disease Mortality. Luepker RV, Higgins MH (Eds). Oxford University Press, 1988. Layout table for additonal information ClinicalTrials.gov Identifier: Other Study ID Numbers: 1075 First Posted: May 26, 2000 Last Update Posted

2000 Clinical Trials

12063. Epidemiology and Pulmonary Response To Organic Dust Exposure

the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: up to 100 Years (Child, Adult, Older Adult) Sexes Eligible for Study: Male Accepts Healthy Volunteers (...) : No Criteria No eligibility criteria Contacts and Locations Go to No Contacts or Locations Provided More Information Go to Publications: Merchant JA: Agricultural Respiratory Disease, In: Seminars in Respiratory Medicine - Vol. 7, Number 3. Thieme Inc, pp 211-224, New York, 1986 Merchant JA: Silicosis Issues - Past, Present, Future. Published in Book: Silica, Silicosis, and Cancer: Controversy in Occupational Medicine, 1986, Goldsmith DF, Winn DM, Shy CM (Eds), Praeger Special Studies, Praeger Scientific

2000 Clinical Trials

12064. Tucson Epidemiology Study of Chronic Obstructive Lung Diseases

in the Atmospheric Environment: A Discussion. J Air Polln Control Assn, 33(9):832-834, 1983 Lebowitz MD, Dodge RR, Holberg CJ, Corman G, Boyer B: Daily Symptoms Related to Indoor Pollution in Adult Asthmatics and Non-Asthmatics. Am J Epidemiol, 118(3):419, 1983 Burrows B: COPD: A New Look at DX and RX of an Old Problem. Modern Med, pp. 114-126, March, 1983 Burrows B, Knudson RJ, Quan SF, Kettel LJ: Respiratory Disorders: A Pathophysiologic Approach, 2nd Ed. Revised. Chicago: Year Book Medical Publishers, Inc (...) : An International Comparison. Med Thoracica, 10:189-93, 1988 Lebowitz MD: Allergy Sufferers in the Southwest. Medical and Health Annual Chicago: Encyclopedia Britannica, pp. 274-276, 1988 Burrows B: Distribution of Allergy in the General Population. In: Bronchits IV. Proceedings Royal Van Gorcum Assen. The Netherlands. pp. 3-13, 1989 Burrows B: Allergy and Its Relationship to Asthma, Bronchial Reactivity and Chronic Airways Obstruction: An Epidemiological Perspective. In: S.T. Weiss and D. Sparrow (Eds

2000 Clinical Trials

12065. National Longitudinal Mortality Study (NLMS)

. Study Design Go to Layout table for study information Study Type : Observational Study Start Date : July 1983 Actual Study Completion Date : December 2009 Groups and Cohorts Go to Outcome Measures Go to Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact (...) the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: up to 100 Years (Child, Adult, Older Adult) Sexes Eligible for Study: Male Accepts Healthy Volunteers: No Criteria No eligibility criteria Contacts and Locations Go to No Contacts or Locations Provided More Information Go to Additional Information: Study Data/Documents: Identifier: NLMS Public-use IPD through BioLINCC. Registration is required for access

2000 Clinical Trials

12066. Exercise Training and Plasma Lipoproteins in Man

Go to Outcome Measures Go to Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 25 Years to 49 Years (Adult (...) Detailed Description: BACKGROUND: Evidence appears to be fairly conclusive that obesity has adverse effects on health and longevity when the relative body weight is 40 percent above desirable weight based on insurance industry tables of weights. The close association between obesity, hypertension, hypercholesterolemia, non-insulin dependent diabetes mellitus, an excess of certain cancers and other medical problems makes it imperative that interventions be directed to change the lifestyles and behaviors

1999 Clinical Trials

12067. Hypertension Detection and Follow-up Program (HDFP)

with fixed diastolic blood pressure over 105 mm Hg. Similar trends occurred for those with fixed diastolic blood pressure between 90 and 104 mm Hg. Results and current trends from other studies supported these findings. However, prior to inception of the Hypertension Detection and Follow-up Program (HDFP), it was not known whether benefits from antihypertensive therapy applied to all hypertensives in the general population and whether making use of existing medical knowledge could significantly reduce (...) , and antihypertensive program could significantly reduce morbidity and mortality in hypertensives in the general population. The planning of the trial, including the development of a protocol and manual of operations, began in 1971. Between February 1973 and May 1974, 158,906 persons were screened for high blood pressure in 14 communities. A total of 10,940 hypertensive participants were randomized. The primary hypothesis tested by the trial was that intensive blood pressure control under stepped care for five

1999 Clinical Trials

12068. Low Back Pain Patient Education Evaluation

intervention that allows subjects to talk with each other and with health professionals via an Internet discussion group. The intervention consists of a book and a videotape and is based on interaction with other participants in the program and health professionals through a closed password protected moderated Internet discussion group. Outcome measures include health behaviors, such as exercise; health status, such as pain and disability; and health care use, such as number of visits to doctors and other (...) Actual Primary Completion Date : February 2002 Actual Study Completion Date : February 2002 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: email discussion group Procedure: Patient education evaluation No Intervention: rancomized control group usual care Outcome Measures Go to Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important

1999 Clinical Trials

12069. Lipid Research Clinics Population Studies

Date : December 1994 Groups and Cohorts Go to Outcome Measures Go to Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible (...) Summary: To conduct epidemiologic surveys of the distribution, causes, and consequences of the dyslipoproteinemias. The Population Studies include the Prevalence Study, the Family Study, and the Mortality Follow-up Study and shared the same general population base. Condition or disease Cardiovascular Diseases Atherosclerosis Coronary Disease Heart Diseases Hyperlipoproteinemia Study Design Go to Layout table for study information Study Type : Observational Study Start Date : July 1972 Study Completion

2000 Clinical Trials

12070. Bogalusa Heart Study

to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: Child, Adult, Older Adult Sexes Eligible for Study: All Accepts Healthy Volunteers (...) . Strong, Ed.) Grune and Stratton, New York, p. 85, 1978 Berenson GS: Children, the Next Generation of Patients with Myocardial Infarction. Proceedings of the International Kronberg Symposium, Frankfurt, Germany, May 1977. Changes in the Medical Panorama, (G. Schettler, J. Drews, and H. Greten, Eds.) Georg Thieme Publishers, Stuttgart, Germany, p. 75, 1978 Berenson GS, Voors AW, Webber LS: Blood Pressure Levels in Black and White Children Related to the Early Onset of Essential Hypertension

2000 Clinical Trials

12071. Evans County Studies

from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: up to 100 Years (Child, Adult, Older Adult) Sexes Eligible for Study: Male Accepts Healthy (...) Volunteers: No Criteria No eligibility criteria Contacts and Locations Go to No Contacts or Locations Provided More Information Go to Publications: Johnson MA, Dooley SP, Caster WO, Hames CG: The Relationship Between Dietary Calcium and Blood Pressure in the Elderly. J Clin Exp Gerontology, 8: (3 & 4), 161-172, 1986 Combs GF, Spallholz JE, Levander OA, Oldfield JE: Selenium in Biology and Medicine, Third lnternational Symposium, Beijing, China. Two Books, Parts A and B, published in 1987 Hames CG

2000 Clinical Trials

12072. Antenatal care in Belfast (Full text)

Antenatal care in Belfast A questionnaire study of mothers' views of the antenatal care provided in Belfast showed general satisfaction. Retrospective examination of their charts however showed in some cases that insufficient attention was paid to the medical and obstetric history in the selection of type of care made by the women and their doctors. Some women with high risk factors were booked for shared care and some patients at low risk were booked for total hospital care. The reasons (...) for this are unclear.The mothers felt that continuity of care and communication at the health centre were better than at the hospital. Analysis of the number of hospital attendances showed that shared care patients appeared to be making an excessive number of visits to hospital. Many total hospital care patients also admitted that they were attending their general practitioners. There appeared to be marked duplication of effort as a result of poor communication between patient, general practitioner

1987 The Ulster medical journal PubMed abstract

12073. Les infections: Un livre de médecine conçu et structure selon la démarche de l'omnipraticien (Full text)

Les infections: Un livre de médecine conçu et structure selon la démarche de l'omnipraticien A book on infectious diseases based directly on clinical practice has been produced for family physicians. It identifies clear objectives oriented towards resolution of clinical problems. The book is organized on four fundamental principles: 1. to respond to pertinent problems in the practice of general medicine; 2. to respect the process of the family doctor's clinical practice, taking into account

1982 Canadian Family Physician PubMed abstract

12074. The contributions of the Second Auxiliary Surgical Group to military surgery during World War II with special reference to thoracic surgery. (Full text)

The contributions of the Second Auxiliary Surgical Group to military surgery during World War II with special reference to thoracic surgery. The outstanding scientific and surgical accomplishments of the Second Auxiliary Surgical Group in the Mediterranean Theater of Operations and the 7th Army in World War II were not exceeded by any other group in the United States Army Medical Corps. In the final 921-page report to the Surgeon General with 550 tables, 8801 severely wounded casualties out (...) of a total of 22,000 treated were reviewed. In addition, the major portion of three books on war surgery and over 60 scientific articles were written by this group. The contributions in thoracic surgery that focused attention on physiologic principles and limited the indications for thoracotomy have stood the test of time. The author made the original description of the reaction of the lung to severe trauma of the brain, abdomen, and extremities by the development of "the wet lung of trauma" (RDS), while

1983 Annals of Surgery PubMed abstract

12075. "Human guinea pigs"--a history. (Full text)

Human Experimentation Research Subjects Social Control, Formal United Kingdom 32135 In 1967, Pappworth expanded a 1962 journal article on unethical experiments with human subjects into a book, Human Guinea Pigs: Experimentation on Man (Routledge). Here Pappworth describes the impetus behind his controversial article and book, and the reaction to both from the British media, the British medical establishment, the Ministry of Health, and Parliament. He discusses the effectiveness of ethical codes (...) , editorial policies, and research ethics committees in safeguarding human subjects from overzealous or unethical researchers. He warns of the need for all those involved in human experimentation -- researchers, their units, ethics committees, editors of medical journals -- to tighten the self regulatory mechanisms in place lest public reaction to unethical research bring on legal sanctions. Analytical Approach Biomedical and Behavioral Research General Medical Council (Great Britain) Human Guinea Pigs

1990 BMJ : British Medical Journal PubMed abstract

12076. Consultation time, workload, and problems for audit in outpatient clinics. (Full text)

Consultation time, workload, and problems for audit in outpatient clinics. Fifty four of 74 paediatricians in the West Midlands (43 general medical, 11 subspecialist) replied to a postal questionnaire about their outpatient practice: 37 timed each consultation in one clinic. On average, subspecialty consultations lasted 37 minutes for new patients and 29 minutes for review. In general clinics new patient consultations took 23 minutes, review 12. Mean 'single handed' general clinic size was 18 (...) , clinics with assistants 24; subspecialist clinics nine and 15. Four to five new patients and nine to 19 review patients were booked per clinic on average; 17/51 clinics used block booking, 34 provided individual appointment times. Mean referral delay was 4.9 weeks, mean clinic wait 22 minutes, and non-attendance averages 16-29%. Solutions are suggested to four main problems: non-attendance, referral delay, unpunctuality and disorganisation, with audit levels for paediatric outpatient activity.

1992 Archives of Disease in Childhood PubMed abstract

12077. Non-admission or non-invitation? A case-control study of failed admissions. (Full text)

Non-admission or non-invitation? A case-control study of failed admissions. To examine the causes of non-admission to hospital.Validation of published rates of non-admission by examination of medical records, followed by a case-control study of non-attenders (cases) and attenders (controls).General hospital.246 Patients (cases in the case-control study) booked for admissions in four specialties (general surgery, gynaecology, otorhinolaryngology, and trauma and orthopaedics) during April, May (...) , and June 1987 who were not admitted for reasons that seemed to be attributable to the patients. Controls comprised 167 patients admitted to the same specialty on the same day.The validation of administrative records indicated that it is unusual for patients to fail to present for admission without advising the hospital beforehand; this occurred in only 1-3% of all bookings. Information on the circumstances of non-admission and clinical and personal details were collected by means of a six page

1989 BMJ : British Medical Journal PubMed abstract

12078. A surgeon with AIDS made the most of borrowed time. (Full text)

A surgeon with AIDS made the most of borrowed time. Dr. Orville Messenger and his wife, Dorothy wrote a book, Borrowed Time, which chronicled his decade-long struggle with AIDS. The disease developed following a 1985 blood transfusion. A general and thoracic surgeon who also worked for the Canadian Medical Protective Association, Dr. Messenger wrote the book to raise public awareness, and money for AIDS research, prevention and treatment. He died Dec. 13, 1995--exactly 10 years after being told

1996 CMAJ: Canadian Medical Association Journal PubMed abstract

12079. Management of labour in an isolated rural maternity hospital. (Full text)

1991.Mode of delivery and complications by place of booking and place of delivery; need for medical intervention and transfer.530 women (53%) were booked for delivery in the rural unit; this group had a caesarean section rate of 3.8% and an unplanned transfer rate of 12.8% to the consultant unit in labour. Of the 462 who delivered in the low risk unit, 25 (5%) required a forceps delivery; postnatal complications requiring emergency medical support occurred in a further 33 (7%).Risk characterisation (...) is possible, but medical support from general practitioners and obstetricians is required in almost a third of women at low risk for complications of delivery. Results of this study support the team approach to obstetric management but not the move towards isolated units without organised medical support.

1996 BMJ : British Medical Journal PubMed abstract

12080. Evaluating perinatal mortality rates: effects of referral and case mix. (Full text)

perinatal mortality rates and rates adjusted for case mix.An estimated 11,701 of the 28,750 women booked for delivery in general practitioner maternity units were transferred to consultant units during their pregnancy. These 11,701 women had a high perinatal mortality rate (16.8/1000 deliveries). Perinatal mortality rates by place of booking showed little difference between general practitioner units (8.8/1000) and consultant units (9.3-11.7/1000). Perinatal mortality rates by place of delivery, however (...) , showed substantial differences between general practitioner units (3.3/1000) and consultant units (9.4-12.6/1000) because of the selective referral of high risk women from general practitioner units to consultant units. Adjustment for risk factors made little difference to the rates except when the subset of deaths due to immaturity was adjusted for birth weight.Perinatal mortality rates should be adjusted for case mix and referral patterns to get a meaningful result. Even when this is done

1993 BMJ : British Medical Journal PubMed abstract

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