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12021. An RCT to Evaluate Incidence, Cost and Clinical Outcomes Using 75 vs 100g. Screening Methods for Gestational Diabetes

related topics: Groups and Cohorts Go to Outcome Measures Go to Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible (...) methodology. Outline: Pregnant women referred as outpatients for glucose testing for GDM will be given a study information sheet by obstetrics staff. At the time of booking the test they will be reminded of the study and to arrive fasting. On the day of glucose testing, the research assistant will invite patients to participate, obtain consent and perform randomisation into one three groups: (1) 50g screen ± 100g 3h GTT; (2) 50g screen ± 75g 2h GTT; or (3) 75g 2h GTT. During the glucose test, study

2006 Clinical Trials

12022. Preoperative Assessment for Synchronous Carcinoma or Polyps With Magnetic Resonance (MR) Colonography

Sponsor: Herlev Hospital Collaborator: University Hospital, Gentofte, Copenhagen Information provided by: Herlev Hospital Study Details Study Description Go to Brief Summary: The purpose of this study is to diagnose possible synchronous carcinomas and polyps with magnetic resonance (MR) colonography in patients booked for operation because of carcinoma in the descending or sigmoid colon, where a preoperative full colonoscopy is not possible. Two days before colonography, patients ingest a 200 ml (...) synchronous cancer or larger polyps Outcome Measures Go to Primary Outcome Measures : Feasibility of MR colonography to diagnose possible synchronous carcinomas and polyps [ Time Frame: 3 ] Secondary Outcome Measures : Altered operative strategy due to findings on MR colonography [ Time Frame: 3 ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about

2006 Clinical Trials

12023. Pacemaker Therapy in Adults With Congenital Heart Defects

With Congenital Heart Defects The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00303511 Recruitment Status : Completed First Posted : March 17, 2006 Results First Posted : August 8, 2014 Last Update Posted : August 8, 2014 Sponsor: Emory University Information provided by (Responsible Party): Wendy M. Book (...) : Retrospective Official Title: Pacemaker Therapy in Adults With Congenital Heart Defects Study Start Date : January 1996 Actual Primary Completion Date : August 2006 Actual Study Completion Date : August 2006 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Outcome Measures Go to Primary Outcome Measures : Feasibility of Pacemaker Implant With Total Thoracoscopic Approach to Epicardial Pacing Lead [ Time Frame: 30 days ] The ability to place a pacemaker

2006 Clinical Trials

12024. Effect of Cemented Stem Design on Periprosthetic Bone Mass Following Primary Total Hip Arthroplasty

provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 60 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Sampling Method: Non-Probability Sample Study Population Pre-assessment clinics at Sheffield Hospitals, patients booked for hip replacements. Criteria Inclusion Criteria: patients must be aged 60 yrs or more uncomplicated primary or secondary osteoarthritis of the hip undergoing unilateral cemented (...) Completion Date : April 2011 Resource links provided by the National Library of Medicine related topics: related topics: Groups and Cohorts Go to Group/Cohort Intervention/treatment 1 C-stem implant Procedure: Total Hip Replacement Implantation of one of 3 stem designs 2 Charnley Implant Procedure: Total Hip Replacement Implantation of one of 3 stem designs 3 Exeter Implant Procedure: Total Hip Replacement Implantation of one of 3 stem designs Outcome Measures Go to Primary Outcome Measures : Proximal

2006 Clinical Trials

12025. Spironolactone in Patients With Single Ventricle Heart

Test Score [ Time Frame: Baseline, Post-Intervention (4 Weeks) ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible (...) : Interventional (Clinical Trial) Actual Enrollment : 12 participants Allocation: Non-Randomized Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Impact of Spironolactone on Endothelial Function in Patients With Single Ventricle Heart Study Start Date : November 2004 Actual Primary Completion Date : June 2008 Actual Study Completion Date : June 2008 Resource links provided by the National Library of Medicine available for: resources: Arms

2005 Clinical Trials

12026. Minimal and Brief Treatments for Pathological Gamblers

of problems related to gambling are on the rise. The costs of problem gambling are enormous.There are social and economic costs, the gambler can sometimes lose a significant relationship, job, or commit an illegal activity. Pathological gamblers are also at risk for developing a general medical condition related to stress. There is a high risk of suicide and problem gamblers also have increased rates of mental health disorders. Relatively few people choose to attend formal treatment programs so it's (...) to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy

2005 Clinical Trials

12027. Subacromial Decompression Versus Subacromial Bursectomy for Patients With Rotator Cuff Tendinosis

or adequately participate in this study due to a language barrier or psychiatric illness. Patients with a major medical illness whose condition or treatment would affect their quality of life and, as such, affect the results of this study. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its (...) ClinicalTrials.gov identifier (NCT number): NCT00196573 Locations Layout table for location information Canada, Alberta University of Calgary Sport Medicine Centre Calgary, Alberta, Canada, T2N 1N4 Canada, British Columbia Royal Columbian Hospital New Westminster, British Columbia, Canada, V3L 5P5 Canada, Manitoba Pan Am Medical and Surgical Centre Winnipeg, Manitoba, Canada, R3M 3E4 Canada, Ontario Fowler Kennedy Sport Medicine Clinic London, Ontario, Canada, N6A 3K7 Hand and Upper Limb Clinic London, Ontario

2005 Clinical Trials

12028. Can Education for South Asians With Asthma and Their Clinicians Reduce Unscheduled Care? A Randomised Trial

date ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 3 Years to 65 Years (Child, Adult, Older Adult (...) and practice nurses, using our adaptation of an American education course, designed to improve shared-decision making, goal-setting and patient-clinician partnership. Lay-led 'expert-patient' education in small groups for patients, using an adaptation of another American course. Improved follow-up in primary care through appointment-booking by the specialist nurse.We will invite south Asians aged 3-65 years with asthma after A&E attendance or hospital admission to take part. Those registered with practices

2005 Clinical Trials

12029. Heart Failure in Adult Patients With a History of Congenital Heart Disease

. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: Child, Adult, Older Adult Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Adults who have a history of congenital heart defects Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your (...) ): Wendy M. Book, Emory University Study Details Study Description Go to Brief Summary: In today's world of advanced surgery, children born with congenital heart disease (CHD) are surviving into adulthood. However, the surgical procedures these children undergo do not cure the underlying problem and this these children develop other heart problems later in life. Heart failure is the one of the most common heart problems effecting these patients. This heart failure can be seen in both lower pumping

2005 Clinical Trials

12030. Effectiveness of a Low Carbohydrate Diet Versus a High Carbohydrate Diet in Promoting Weight Loss and Improved Health

: every six months ] neuroendocrine mechanisms of hunger and satiety [ Time Frame: end of study ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility (...) . History of psychiatric hospitalization within 2 years prior to study entry Consumption of more than three alcoholic drinks a day Type I or II diabetes Current use of hypolipidemics, antipsychotics, hypoglycemics, glucocorticoids, or thyroid medication Plan to move during study Current participation in another clinical trial Pregnancy or breastfeeding Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study

2005 Clinical Trials

12031. Treatment for Nonspecific Low Back Pain in Primary Care: a Trial on Different Health Education Booklets

of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: 1 The Back Book Behavioral: The Back Book A book on how to prevent back pain Behavioral: The Back Guide A guide for the prevention of back pain. Behavioral: General health book A book on general health Active Comparator: 2 The Back Guide Behavioral: The Back Guide A guide for the prevention of back pain. Behavioral: General health book A book on general health Active Comparator: 3 General health book (...) Behavioral: General health book A book on general health Outcome Measures Go to Primary Outcome Measures : Degree of disability at 180 days of follow-up. [ Time Frame: 6 months ] Secondary Outcome Measures : Catastrophizing and days on sick leave at 180 days of follow-up. [ Time Frame: 6 months ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about

2006 Clinical Trials

12032. Genetic Studies in the Amish and Mennonites

History and other genealogy books ordatabases will be included in the AGDB. Outcome Measures Go to Primary Outcome Measures : Database [ Time Frame: Ongoing ] To maintain, expand, and use an electronic database containing the Anabaptist genealogies to facilitate the generation of pedigrees and calculation of common ancestors between nuclear families. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk (...) A: Patients and their families with known or suspected Mendelian or complex traits, who will be enrolled in the molecular genetics and phenotypic characterization study. Informed consent will be obtained from each of these subjects. Group B: Those individuals who are listed in the Fisher Family History and multiple other genealogy books will be included in the AGD database. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may

2006 Clinical Trials

12033. Ketamine on Acute Pain in Females and Males

Completion Date : November 2006 Resource links provided by the National Library of Medicine available for: Arms and Interventions Go to Arm Intervention/treatment Placebo Comparator: Placebo males Saline physiological placebo males Drug: Placebo males Intravenous saline bolus (Placebo-control) males Other Name: saline physiological 5 ml Active Comparator: Ketamine 0,1 mg/kg males 0,1 mg/kg ketamine males Drug: Ketamine 0,1 mg/kg males 0,1 mg/kg ketamine iv bolus males Other Name: Ketalar ATC-nr.: N01A (...) mg/kg iv bolus ketamine females Other Name: Ketalar ATC-nr.: N01A X03 Outcome Measures Go to Primary Outcome Measures : Sum pain NRS [ Time Frame: 60 min ] Secondary Outcome Measures : Several subjective variables assessing psychotomimetic effects [ Time Frame: 0, 15, 60 ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join

2005 Clinical Trials

12034. Pioglitazone as a Treatment for Lipid and Glucose Abnormalities In Patients With Schizophrenia

Detailed Description: The aim of this study is to investigate the effects of pioglitazone added to weight-lifestyle intervention vs. placebo plus lifestyle intervention on reversing or reducing impaired or abnormal triglycerides, HDL and glucose metabolism in schizophrenics treated with first or second-generation antipsychotics.. Another aim is to examine the effects of impaired glucose metabolism on verbal memory and other cognitive function in schizophrenic patients treated with these medications (...) : Pioglitazone as a Treatment for Lipid and Glucose Abnormalities In Patients With Schizophrenia Treated With Antipsychotic Medication And Potential Effects on Cognitive Function Study Start Date : May 2005 Actual Primary Completion Date : January 2010 Actual Study Completion Date : January 2010 Resource links provided by the National Library of Medicine related topics: related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: Pioglitazone and life-style group

2005 Clinical Trials

12035. Intra-op Lidocaine and Ketamine Effect on Postoperative Bowel Function

infection, dehiscence and other surgical complications time to readiness for discharge from hospital Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility (...) Start Date : September 2005 Actual Study Completion Date : November 2006 Resource links provided by the National Library of Medicine available for: Arms and Interventions Go to Outcome Measures Go to Primary Outcome Measures : Mean time after surgery to completion of the following postoperative markers: drinking and retaining 500ml clear fluids, presence of bowel sounds passage of flatus, and passage of stool. Secondary Outcome Measures : pain after cough by VAS narcotic usage nausea vomiting

2005 Clinical Trials

12036. Resynchronization/Defibrillation for Ambulatory Heart Failure Trial

mortality and hospitalizations for CHF. Condition or disease Intervention/treatment Phase Heart Failure, Congestive Device: Optimal Medical Therapy plus ICD Device: Optimal Medical Therapy plus CRT/ICD Not Applicable Detailed Description: Cardiovascular mortality is decreasing in most industrial countries, however mortality for congestive heart failure is increasing. The most important predictors of mortality in heart failure patients are depressed left ventricular function, severity of symptoms (NYHA (...) QRS and mild to moderate heart failure symptoms. This is a double-blinded randomized control trial. A total of 1800 patients with mild to moderate heart failure symptoms, LVEF ≤ 30%, and QRS ≥ 120 ms will be included in the study. Patients will be randomized to either "ICD plus Optimal Medical Therapy (control)" or "CRT/ICD plus Optimal Medical Therapy (experimental)" in a 1:1 randomization ratio. Patients in the control group will be implanted with a single or dual chamber ICD. Patients

2005 Clinical Trials

12037. Ph I:Bevacizumab + Chemotherapy in Pts w/Malig Pleural Effusion Due to Adv NSCLC

practice. Pleural fluid will be drained from the Pleur-XTM at least every other day (qod), and volume recorded by the patient in a log book. Pleur-XTM catheters may be removed when pleural symphysis is achieved (defined in Section 12.0), or at the discretion of the treating physician. The schedule of follow-up visits may vary according to the chemotherapy regimen, however all patients must be evaluated in the clinic at least every 3 weeks with a doctor visit to record drainage volume, and status (...) Actual Study Completion Date : April 2008 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Intervention Details: Drug: bevacizumab with chemotherapy, Pleur-XTM catheter placement After Pleur-XTM catheter placement patients will receive bevacizumab 15mg/kg IV x 1 dose as a single agent.Three weeks later, chemotherapy will be initiated according to routine clinical practice along with continued use of bevacizumab. Outcome Measures

2005 Clinical Trials

12038. The V-Tachogram:Decreasing Ventricular Arrythmias When Injecting Contrast in the Left Ventricle

research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: Child, Adult, Older Adult Sexes Eligible for Study: All Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: Only ventriculograms that the operator deems necessary for the booked procedure will be considered. Only operators agreeing to the for mentioned settings will participate in the study. Patients will be randomized consecutively and should conclude (...) Model: Natural History Time Perspective: Cross-Sectional Time Perspective: Prospective Study Start Date : July 2006 Study Completion Date : August 2006 Groups and Cohorts Go to Outcome Measures Go to Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study

2006 Clinical Trials

12039. Percutaneous Interventions in Adults With CHD

congenital heart disease including Eisenmenger’s Syndrome, single ventricle, pulmonary atresia with aorticopulmonary collaterals, complete atrio-ventricular canal defects, double inlet left ventricle, heterotaxy syndromes and truncus arteriosus. Patients with surgically placed systemic to pulmonary artery shunts will be included. Although generally incompatible with adult survival, rare patients with un-operated or palliated complex cyanotic congenital heart defects (CCHD) survive well into adulthood (...) . Symptoms related to poor pulmonary blood flow and/ or increasing pulmonary vascular resistance progress with advancing age. Percutaneous interventions to improve symptoms and relieve hypoxemia have not been previously reported in adult patients with complex cyanotic congenital heart disease. Percutaneous interventions in patients with cyanotic congenital heart disease may be generally broken down into three types: percutaneous occlusion of shunt lesions, percutaneous balloon valvotomy or valvuloplasty

2005 Clinical Trials

12040. Eisenmenger's Syndrome in Adults With CHD

: Review the outcome of treatment with endothelin receptor antagonists (bosentan or sitaxsetan) alone or in combination with Sildenafil (a PDE-5 inhibitor) in adult patients with pulmonary hypertension due to congenital heart disease. Condition or disease Congenital Disorders Detailed Description: The primary objective of this study is to examine medical records of patients with Eisenmenger's Syndrome in order to determine the effect of endothelin receptor antagonists, alone or in combination (...) Resource links provided by the National Library of Medicine related topics: resources: Groups and Cohorts Go to Outcome Measures Go to Primary Outcome Measures : Review the outcome of treatment with endothelin receptor antagonists (bosentan or sitaxsetan) alone or in combination with Sildenafil (a PDE-5 inhibitor) in adult patients with pulmonary hypertension due to congenital heart disease [ Time Frame: 12 years ] Our study demonstrates that endothelin receptor blockers can be used to improve exercise

2005 Clinical Trials

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