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10661. Azapirones for generalized anxiety disorder. (PubMed)

searched on 21-10-2005. Reference lists of relevant papers and major text books of anxiety disorder were examined. Authors, other experts in the field and pharmaceutical companies were contacted for knowledge of suitable trials, published or unpublished. Specialist journals concerning azapirones were handsearched.Randomized controlled trials of azapirones, including buspirone versus placebo and/or other medication and/or psychological treatment, were included. Participants were males and females of all (...) ages with a diagnosis of generalized anxiety disorder.Data were extracted from the original reports independently by CC, MA and MT. The main outcomes studied were related to the objectives stated above. Data were analysed for generalized anxiety disorder versus placebo, versus other medication and versus psychological treatment separately. Data were analysed using Review Manager Version 4.2.7.Thirty six trials were included in the review, reporting on 5908 participants randomly allocated

2006 Cochrane

10662. The short-term effect of interdisciplinary medication review on function and cost in ambulatory elderly people

usage, a brown bag review was conducted to determine the generic and brand name, dosage indicated, prescribed frequency of ingestion, length of use, patient's perception of purpose and efficacy, actual use of medication, and drug-related problems. At analysis, the groups were shown to be comparable in terms of age, gender, demographic and socioeconomic factors. Effectiveness results No statistically significant differences in cognitive, affective, or physical functioning were observed between (...) , it was unclear who paid for these medications. The 1995 Red Book was used to price all medications at the average wholesale price and to label them as prescription or non-prescription. The total daily usage was coded and priced according to patient report or labelling. As-needed usage was priced at a minimal usage rate of one dose or dosage regimen per month for most products, and at one dose or dosage regimen for those deemed likely to be used more frequently. Discounting was not relevant since all

2004 NHS Economic Evaluation Database.

10663. Computer telephony: automated calls for medical care

reporting make it difficult to verify the findings. Authors' objectives To assess the evidence for computer telephony system (CTS)-based medical interventions. Searching MEDLINE (from 1966 to April 2003), CINAHL (from 1982 to April 2003) and the Cochrane Controlled Trials Register were searched using the search terms listed in the review. The reference lists of retrieved studies, reviews and reference books were also handsearched. The search was restricted to studies published in English. Study (...) Computer telephony: automated calls for medical care Computer telephony: automated calls for medical care Computer telephony: automated calls for medical care Biem H J, Turnell R W, D'Arcy C CRD summary This review assessed the evidence for computer telephony-based interventions in health care delivery, preventive care and the management of chronic diseases. The authors concluded that the evidence is limited and more research is needed in this field. The poor quality assessment and poor

2003 DARE.

10664. Cost-effectiveness of early irbesartan treatment versus control (standard antihypertension medications excluding ACE inhibitors, other angiotensin-2 receptor antagonists, and dihydropyridine calcium channel blockers) or late irbesartan treatment in patien

Cost-effectiveness of early irbesartan treatment versus control (standard antihypertension medications excluding ACE inhibitors, other angiotensin-2 receptor antagonists, and dihydropyridine calcium channel blockers) or late irbesartan treatment in patien Cost-effectiveness of early irbesartan treatment versus control (standard antihypertension medications excluding ACE inhibitors, other angiotensin-2 receptor antagonists, and dihydropyridine calcium channel blockers) or late irbesartan (...) treatment in patients with Type 2 diabetes, hypertension, and renal disease Cost-effectiveness of early irbesartan treatment versus control (standard antihypertension medications excluding ACE inhibitors, other angiotensin-2 receptor antagonists, and dihydropyridine calcium channel blockers) or late irbesartan treatment in patients with Type 2 diabetes, hypertension, and renal disease Palmer A J, Annemans L, Roze S, Lamotte M, Lapuerta P, Chen R, Gabriel S, Carita P, Rodby R A, De Zeeuw D, Parving H H

2004 NHS Economic Evaluation Database.

10665. The Acutely or Critically Sick or Injured Child in the District General Hospital

CriticalSickChild txt 26/10/06 16:46 Page iDH INFORMATION READER BOX Policy HR/Workforce Management Planning Clinical Estates Performance IM&T Finance Partnership working Document purpose For information Gateway reference 6369 Title The acutely or critically sick or injured child in the district general hospital: A team response Authors DH, RCPCH, RCoA, RCN, RCS, APA and BAPS Publication date October 2006 Target audience NHS trust CEs, foundation trust CEs and medical directors Circulation list Strategic health (...) authority CEs and emergency care leads Description An inter-collegiate expert working group has considered issues regarding anaesthetic and other services available to children who are critically sick or injured in district general hospitals, and has produced this report. It was open to consultation between August and December 2005 and was finalised with the benefit of comments received. Cross-reference N/A Superseded documents N/A Action required N/A Timing N/A Contact details Dr Edward Wozniak Medical

2006 Royal College of Anaesthetists

10666. Medical emergencies in children ? overview

- hospital care this generally means management designed to: ? prevent hypoxia (see above) ? normalise circulation (but do not overload) ? check for and treat hypoglycaemia (refer to glycaemic emergencies in children guideline). Medical Emergencies in Children – overview Paediatric Guidelines October 2006 Page 5 of 7 Paediatric GuidelinesOther conditions which can be treated before hospital and are discussed elsewhere include: ? convulsions (refer to convulsions in children guideline) ? opiate poisoning (...) you blush! Pre-hospital Immediate Care 1998;2:95-96. Jewkes F, Lubas P, McCusker K, editors. Pre- hospital Paediatric Life Support 2nd ed. London: Blackwells, 2005. Group ALS. Pre-hospital paediatric life support. London: BMJ Publishing Group, 1999. Advanced Life Support Group. Advanced paediatric life support: the practical approach. 3rd ed. London: BMJ Books, 2000. METHODOLOGY Refer to methodology section. Medical Emergencies in Children – overview Page 6 of 7 October 2006 Paediatric Guidelines

2006 Joint Royal Colleges Ambulance Liaison Committee

10667. Paediatric - medical emergencies in children (overview)

- hospital care this generally means management designed to: ? prevent hypoxia (see above) ? normalise circulation (but do not overload) ? check for and treat hypoglycaemia (refer to glycaemic emergencies in children guideline). Medical Emergencies in Children – overview Paediatric Guidelines October 2006 Page 5 of 7 Paediatric GuidelinesOther conditions which can be treated before hospital and are discussed elsewhere include: ? convulsions (refer to convulsions in children guideline) ? opiate poisoning (...) you blush! Pre-hospital Immediate Care 1998;2:95-96. Jewkes F, Lubas P, McCusker K, editors. Pre- hospital Paediatric Life Support 2nd ed. London: Blackwells, 2005. Group ALS. Pre-hospital paediatric life support. London: BMJ Publishing Group, 1999. Advanced Life Support Group. Advanced paediatric life support: the practical approach. 3rd ed. London: BMJ Books, 2000. METHODOLOGY Refer to methodology section. Medical Emergencies in Children – overview Page 6 of 7 October 2006 Paediatric Guidelines

2007 Joint Royal Colleges Ambulance Liaison Committee

10668. Improving Medical Implant Performance Through Retrieval Information: Challenges and Opportunities

, National Institutes of Health. . Abstract Objective: To provide researchers, health care providers, patients, and the general public with a responsible assessment of the opportunities for and challenges of developing a framework for independent research on explanted medical implants. For the purpose of this conference, medical implants are defined as devices that have a minimum lifespan of three months; that penetrate and have a physiologic interaction with living tissue; and that can be retrieved (...) and ventricular assist devices appear to exceed those of alternative therapies such as cardiac allografts (transplants). In general, patient expectations of life-enhancing or life-saving devices include survival, restoration of active lifestyle (function, quality of life, pain relief), gainful employment, and access to replacing the implant if necessary. The last expectation would also apply to form-enhancing implants. Health care provider expectations of the benefits of medical implants are, and should

2000 NIH Consensus Statements

10669. Long-term transcutaneous electrical nerve stimulation (TENS) use: impact on medication utilization and physical therapy costs

Long-term transcutaneous electrical nerve stimulation (TENS) use: impact on medication utilization and physical therapy costs Long-term transcutaneous electrical nerve stimulation (TENS) use: impact on medication utilization and physical therapy costs Long-term transcutaneous electrical nerve stimulation (TENS) use: impact on medication utilization and physical therapy costs Chabal C, Fishbain D A, Weaver M, Heine L W Record Status This is a critical abstract of an economic evaluation (...) completers only. The primary outcome measures were reported for the LTU group and included: satisfaction (overall satisfaction, ease of use/convenience, effectiveness of pain management, quality of device, and comfort of the stimulation); change in pain interference, actual pain relief, and change in medication use from pre-TENS use; change in therapy use; patient perceptions for change in activity level, pain management, help in return to work, and medication use. The effects of potential confounding

1998 NHS Economic Evaluation Database.

10670. Medical outcomes and antimicrobial costs with the use of the American Thoracic Society guidelines for outpatients with community-acquired pneumonia

. The unit costs of the antimicrobial agents were estimated using the published average wholesale price of the least expensive generic equivalent from the 1993 drug Red Book. Statistical analysis of costs The total costs per patient were reported as medians, both for the total figures per patient and the average daily cost per patient. Student's t test was used to compare the groups in terms of costs. A multivariate regression analysis was used to control for the effects of differences in variables (...) Medical outcomes and antimicrobial costs with the use of the American Thoracic Society guidelines for outpatients with community-acquired pneumonia Medical outcomes and antimicrobial costs with the use of the American Thoracic Society guidelines for outpatients with community-acquired pneumonia Medical outcomes and antimicrobial costs with the use of the American Thoracic Society guidelines for outpatients with community-acquired pneumonia Gleason P P, Kapoor W N, Stone R A, Lave J R, Obrosky D

1997 NHS Economic Evaluation Database.

10671. Has general practitioner computing made a difference to patient care: a systematic review of published reports

, BIDS and GPLit were searched from 1984-1994 using the terms 'computers in medicine', 'primary care', 'family practice' and 'medical informatics. Books, bibliographies and conference proceedings were also searched and references were supplied by colleagues. Study selection Study designs of evaluations included in the review Controlled studies with samples formed randomly, quasi randomly, or using selected, concurrent or historical control groups. The designs of individual studies were not stated (...) Has general practitioner computing made a difference to patient care: a systematic review of published reports Has general practitioner computing made a difference to patient care: a systematic review of published reports Has general practitioner computing made a difference to patient care: a systematic review of published reports Sullivan F, Mitchell E Authors' objectives To review findings from studies of the influence of desktop computers on primary care consultations. Searching MEDLINE

1995 DARE.

10672. Randomised controlled trial comparing cost effectiveness of general practitioners and nurse practitioners in primary care

Randomised controlled trial comparing cost effectiveness of general practitioners and nurse practitioners in primary care Randomised controlled trial comparing cost effectiveness of general practitioners and nurse practitioners in primary care Randomised controlled trial comparing cost effectiveness of general practitioners and nurse practitioners in primary care Venning P, Durie A, Roland M, Roberts C, Leese B Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Nurse practitioners working as part of primary care teams alongside general practitioners as first point of contact in primary care for patients requesting an appointment on the same day. Type of intervention Treatment. Economic study type Cost-effectiveness analysis

2000 NHS Economic Evaluation Database.

10673. Relative costs and effectiveness of specialist and general internist ambulatory care for patients with 2 chronic musculoskeletal conditions

and laboratory procedures. Two rheumatologists identified the medication. The resource use data were estimated from actual data. The unit costs were derived from the Boston University Medical Centre 1995 costs, except for medication costs which were based on average wholesale costs from the 15 Drug Topics Red Book. Discounting was carried out because the costs were incurred during more than one year. A discount rate of 3% was used. The unit costs were presented separately from the quantities of resources (...) . Relative costs and effectiveness of specialist and general internist ambulatory care for patients with 2 chronic musculoskeletal conditions. Journal of Rheumatology 2002; 29(7): 1488-1495 PubMedID Other publications of related interest Ware JE, Sherbourne CD. The MOS 36-item Short Form Health Survey (SF-36). I. Conceptual framework and item selection. Medical Care 1992;30:473-83. Kazis L, Miller D, Skinner K, et al. Health related quality of life in patients served by the Department of Veterans Affairs

2002 NHS Economic Evaluation Database.

10674. The relationship between consultation length, process and outcomes in general practice: a systematic review

The relationship between consultation length, process and outcomes in general practice: a systematic review The relationship between consultation length, process and outcomes in general practice: a systematic review The relationship between consultation length, process and outcomes in general practice: a systematic review Wilson A, Childs S Authors' objectives To examine the association between the average consultation time of primary care physicians and consultation process and health outcome (...) eligible. The included studies measured the average consultation length by objective timing of the individual consultation, dividing the consultation session by the number of patients seen, or using the booking interval. Studies were conducted in the USA, Wales, UK, Scotland, the Netherlands and Sweden. Participants included in the review Studies of primary care physicians were eligible for inclusion. Primary care physicians were defined as first contact doctors and included specialist physicians

2002 DARE.

10675. Literature review to inform purchasing of counselling in general practice

assessed in the review No a priori criteria were defined. Effectiveness of counselling was assessed using the following outcomes: measures of morbidity including physician referral, psychiatric interviews and screening with General Heath Questionnaire; criterion-based diagnostic assessments such as the National Institute of Mental Health's Diagnostic Interview Schedules; physician prescribing practices; patients' use of psychotropic medication; number of patient visits to primary care physicians (...) Literature review to inform purchasing of counselling in general practice Literature review to inform purchasing of counselling in general practice Literature review to inform purchasing of counselling in general practice Hansell A, Bonnet J Authors' objectives To examine recent evidence for provision of counselling in general practice to inform service planning for Primary Care Groups (PCGs). Searching The following sources were searched: Cochrane Library (1999 issue 2) and the Department

1999 DARE.

10676. Is there any medical evidence that shows the reason why patients on warfarin are recommended to have their warfarin levels done after the influenza or pneumococcal vaccine?

Is there any medical evidence that shows the reason why patients on warfarin are recommended to have their warfarin levels done after the influenza or pneumococcal vaccine? Is there any medical evidence that shows the reason why patients on warfarin are recommended to have their warfarin levels done after the influenza or pneumococcal vaccine? - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words (...) &As that have been generated over the years by various services Trip Database have run or been involved in. Trip are keen to retain this collection for a historical and research reasons. More results What is Trip? Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care. Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto

2006 TRIP Answers

10677. In children who are receiving routine vaccinations, is there any evidence that giving antipyretic medication reduces the immune response to the vaccine?

antipyretic medication reduces the immune response to the vaccine? We searched the TRIP and Medline databases and found no guidelines or studies that suggest antipyretic medication reduces the immune response to the vaccine. The CKS (PRODIGY) guidance on childhood immunisations, the Green Book (Immunisation Against Infectious Disease) and the NHS Immunisations websites [4] all advise giving an antipyretic, i.e. paracetamol or ibuprofen to children experiencing fever following vaccination: " Parents should (...) also be advised: To give a dose of paracetamol or ibuprofen if fever develops, and keep the child cool by removing excessive clothing and bedding. If fever persists after a second dose, they should seek medical advice." [1] The Green Book discusses the management of vaccine-induced adverse events following immunisation in chapter 8. It states: " Fevers over 37.5¢ªC are common in children and are usually mild. Advice on the use and appropriate dose of paracetamol or ibuprofen liquid to prevent

2007 TRIP Answers

10678. In a medical bookshop (PubMed)

In a medical bookshop 17263941 2007 07 31 2008 11 20 0960-1643 57 535 2007 Feb The British journal of general practice : the journal of the Royal College of General Practitioners Br J Gen Pract In a medical bookshop. 161 Vernon Gervase G eng Journal Article England Br J Gen Pract 9005323 0960-1643 IM Attitude of Health Personnel Empathy Family Practice Humans Reference Books, Medical 2007 2 1 9 0 2007 8 1 9 0 2007 2 1 9 0 ppublish 17263941 PMC2034186

Full Text available with Trip Pro

2007 The British Journal of General Practice

10679. Clinicians' responses to direct-to-consumer advertising of prescription medications. (PubMed)

assistants). No statistically significant differences were found between the early and late responders or between responders and nonresponders. Relative to clinicians who received the "drug reference book" patient scenario, clinicians who received the DTCA patient scenario were more likely to become annoyed with a patient for asking for more information about medications (P =.003); less likely to answer the patient's questions (P =.03) or provide additional written information (P =.007); more likely (...) Clinicians' responses to direct-to-consumer advertising of prescription medications. The direct-to-consumer advertising (DTCA) of prescription medications is proliferating in the United States. The relationship between patient exposure to DTCA and the response of clinicians is not well understood.A randomized postal survey of Arizona primary care provider physicians (n = 1080) and physician assistants (n = 704) was conducted. A questionnaire was created using a hypothetical patient scenario

Full Text available with Trip Pro

2003 Archives of internal medicine

10680. Medical outcome of pregnancy in women with psychotic disorders and their infants in the first year after birth. (PubMed)

Medical outcome of pregnancy in women with psychotic disorders and their infants in the first year after birth. There has been little research into the health of infants of women with psychotic disorders.To investigate the antenatal care of mothers with a history of psychotic disorders, obstetric outcomes and the subsequent health of their babies.A matched, controlled cohort study was carried out using the General Practice Research Database. Women with a history of a psychotic disorder, who (...) gave birth in 1996-1998, were compared with women matched for age and general practice (199 cases and 787 controls) and their infants.Cases had a higher proportion of stillbirths (OR=4.03, 95% CI 1.14-4.25, P=0.03) and neonatal deaths (P<0.001). There was no difference in gestational age at antenatal booking. Mothers with psychotic disorders were less likely than controls to attend for infant immunisations 90-270 days after birth (RR=0.94, 95% CI 0.88-0.99, P=0.03). There was no significant

2003 British Journal of Psychiatry

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