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Functional Aphonia

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61. Brain Mapping of Voice Control

in this study. Condition or disease Voice Disorders Detailed Description: The neural organization of laryngeal motor and somatosensory function will be investigated in adults with idiopathic voice disorders using functional magnetic resonance imaging. Brain activation will be compared in normal volunteers and patients with spasmodic dysphonia (SD), muscle tension dysphonia (MTD) and vocal tremor. While each voice disorder is characterized by strained vocalization, the disorders are distinguished by other (...) differences in voice symptoms. Accordingly, the brain correlates of vocalization in these disorders may both differ from each other and that of normal vocal function. Because sensory feedback has been identified as a factor in SD, the role of afferent input in vocalization will be investigated by comparing brain activation before and after topical anesthesia of the laryngeal mucosa. The afferent blockade is expected to significantly suppress dysphonic symptoms in SD patients for the duration of the block

2003 Clinical Trials

62. Hemicricoidectomy as the primary diagnosis and treatment for cricoid chondrosarcomas. (Abstract)

. This procedure allows sufficient tissue for histological study and provides good long-term breathing and phonatory function without compromising long-term survival. This procedure is appropriate for patients with 1) mobility of one vocal fold, 2) dysphonia or aphonia, and 3) an adequate subglottic airway. (...) Hemicricoidectomy as the primary diagnosis and treatment for cricoid chondrosarcomas. The objective was to present a new approach for the diagnosis and treatment of chondrosarcoma involving the cricoid cartilage. The technique involved an extramucosal resection of the ipsilateral half of the involved cricoid cartilage, providing enough tissue to be sent for pathological study, and resulted in good laryngeal function without jeopardizing patients' long-term survival.Retrospective study.A

2003 Laryngoscope

63. Sensory Function in Idiopathic Voice Disorders

Sensory Function in Idiopathic Voice Disorders Sensory Function in Idiopathic Voice Disorders - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Sensory Function in Idiopathic Voice Disorders The safety (...) disorders and will determine if abnormalities in sensory feedback modulation are involved in idiopathic voice disorders. Such findings will lead to improved understanding of the pathophysiology and differential diagnosis of idiopathic voice disorders and may ultimately improve treatment approaches to these disorders. Study Design Go to Layout table for study information Study Type : Observational Enrollment : 370 participants Official Title: Sensory Function in Idiopathic Voice Disorders Study Start

1999 Clinical Trials

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