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Frontal Lobe

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161. Finally, a Flood of Fascinating Facts and Findings on Final Outcomes After Frontal Lobe Epilepsy Surgery Full Text available with Trip Pro

Finally, a Flood of Fascinating Facts and Findings on Final Outcomes After Frontal Lobe Epilepsy Surgery 24940158 2014 06 18 2018 11 13 1535-7597 14 3 2014 May Epilepsy currents Epilepsy Curr Finally, a flood of fascinating facts and findings on final outcomes after frontal lobe epilepsy surgery. 139-42 10.5698/1535-7597-14.3.139 Hirsch Lawrence J LJ eng Journal Article United States Epilepsy Curr 101135954 1535-7511 2014 6 19 6 0 2014 6 19 6 0 2014 6 19 6 1 ppublish 24940158 10.5698/1535-7597

2014 Epilepsy Currents

162. Morphine increases hippocampal viral load and suppresses frontal lobe CCL5 expression in the LP-BM5 AIDS model Full Text available with Trip Pro

Morphine increases hippocampal viral load and suppresses frontal lobe CCL5 expression in the LP-BM5 AIDS model Chronic opiate abuse accelerates the development of cognitive deficits in human immunodeficiency virus (HIV)-1 patients. To investigate morphine's effects on viral infection of the central nervous system, we applied chronic morphine treatment to the LP-BM5 murine acquired immunodeficiency syndrome (MAIDS) model. LP-BM5 infection induces proinflammatory cytokine/chemokine production (...) , correlating to increased blood-brain barrier permeability. Morphine treatment significantly increased LP-BM5 viral load in the hippocampus, but not in the frontal lobe. Morphine reduced the chemokine CCL5 to non-infected levels in the frontal lobe, but not in the hippocampus. These data indicate a region-specific mechanism for morphine's effects on virally-induced neurocognitive deficits. Copyright © 2014 Elsevier B.V. All rights reserved.

2014 Journal of Neuroimmunology

163. Proteomic profiling of the phosphoproteins in the rat thalamus, hippocampus and frontal lobe after propofol anesthesia. Full Text available with Trip Pro

Proteomic profiling of the phosphoproteins in the rat thalamus, hippocampus and frontal lobe after propofol anesthesia. Propofol is a safe and effective intravenous anesthetic that is widely used for the induction and maintenance of anesthesia during surgery. However, the mechanism by which propofol exerts its anesthetic effect remains unknown. The rapid onset of phosphorylation modifications coincides with that of propofol anesthesia.Propofol-anesthetized rat models were built (...) and phosphorylated proteins in the thalamus, hippocampus and frontal lobe were enriched the to analyze the changes in these phosphoproteins after propofol anesthesia.Sixteen of these phosphoprotein spots were successfully identified using MALDI-TOF MS and a subsequent comparative sequence search in the Mascot database. Of these proteins, keratin 18 and the tubulin 2c chain are cytoskeletal proteins; keratin 18 and gelsolin are relevant to alcohol drowsiness. Based on Western blot analysis, we also confirmed

2014 BMC Anesthesiology

164. Effect of phenylephrine vs. ephedrine on frontal lobe oxygenation during caesarean section with spinal anesthesia: an open label randomized controlled trial. Full Text available with Trip Pro

Effect of phenylephrine vs. ephedrine on frontal lobe oxygenation during caesarean section with spinal anesthesia: an open label randomized controlled trial. During caesarean section spinal anesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine. Phenylephrine is however reported to reduce the near infrared spectroscopy-determined frontal lobe oxygenation (ScO2) but whether that is the case for patients exposed to spinal anesthesia (...) ).In the choice between phenylephrine and ephedrine for maintenance of blood pressure during caesarean section with spinal anesthesia, ephedrine maintains frontal lobe oxygenation and maternal heart rate with a similar increase in fetal heart rate as elicited by phenylephrine.Clinical trials NCT 01509521 and EudraCT 2001 006103 35.

2014 Frontiers in physiology Controlled trial quality: uncertain

165. Right Frontal Sinus Suppuration with Orbital Abscess. Abscess of Left Frontal Lobe producing Bilateral Visual Defects. Operation. Recovery with Partial Blindness Full Text available with Trip Pro

Right Frontal Sinus Suppuration with Orbital Abscess. Abscess of Left Frontal Lobe producing Bilateral Visual Defects. Operation. Recovery with Partial Blindness 19989890 2010 06 24 2010 06 24 0035-9157 27 9 1934 Jul Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Right Frontal Sinus Suppuration with Orbital Abscess. Abscess of Left Frontal Lobe producing Bilateral Visual Defects. Operation. Recovery with Partial Blindness. 1284-5 Brown L G LG eng Journal Article England Proc R

1934 Proceedings of the Royal Society of Medicine

166. Abscess in the Left Cerebral Frontal Lobe, originating from Suppuration in the Left Frontal Sinus Full Text available with Trip Pro

Abscess in the Left Cerebral Frontal Lobe, originating from Suppuration in the Left Frontal Sinus 19972949 2010 06 22 2010 06 22 0035-9157 1 Laryngol Sect 1908 Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Abscess in the Left Cerebral Frontal Lobe, originating from Suppuration in the Left Frontal Sinus. 125-7 Cargill L V LV Turner W W Thomson S S eng Journal Article England Proc R Soc Med 7505890 0035-9157 2009 12 9 6 0 1908 1 1 0 0 1908 1 1 0 1 ppublish 19972949 PMC2046034

1908 Proceedings of the Royal Society of Medicine

167. Tonic Upward Eyeball Deviation Mimicking Non-Convulsive Occipital Lobe Status Epilepticus That Was Induced by Hydrocephalus Full Text available with Trip Pro

Tonic Upward Eyeball Deviation Mimicking Non-Convulsive Occipital Lobe Status Epilepticus That Was Induced by Hydrocephalus Several seizure-like symptoms are difficult to differentiate from epileptic convulsion, and then if they were misdiagnosed, they could be led to grave prognosis. A 41-year-old man was referred to the emergency room due to unconsciousness. Brain computed tomography (CT) revealed acute subdural hemorrhage along the left frontal lobe, and intraparenchymal hemorrhage (...) in the left temporo-occipital lobe. After emergent decompressive craniectomy, he recovered an alert mental state but became progressively drowsy. Four days later, virtually continuous tonic upward eyeball deviation was observed. He had been taking antiepileptic drugs following an occipital lobectomy 20 years prior due to intractable epilepsy, and we assumed these upward eyeball deviations were symptoms of non-convulsive occipital lobe status epilepticus. Hence, doses and classes of antiepileptic drugs

2018 Journal of epilepsy research

168. Correlation of neuropsychological and metabolic changes after epilepsy surgery in patients with left mesial temporal lobe epilepsy with hippocampal sclerosis Full Text available with Trip Pro

in the left mesial temporal regions and occipital lobe. Increased metabolism was observed in the bi-frontal and right parietal lobes, temporal lobes, occipital lobes, thalamus, cerebellum, and vermis. In these regions, we did not find a correlation between changes in metabolism and neuropsychological test scores. A significant negative correlation, however, was found between metabolic changes in the precuneus and Boston Naming Test (BNT) scores.There are significant metabolic decreases in the left mesial (...) temporal regions and increases in the bi-frontal lobes; right parietal, temporal, and occipital lobes; right thalamus; cerebellum; and vermis in patients with left MTLE-HS who were rendered seizure-free after epilepsy surgery. We could not confirm that these changes translate into significant cognitive changes. A significant negative correlation was found between changes in confrontation naming and changes in metabolism in the precuneus. We speculate that the precuneus may play a compensatory role

2018 EJNMMI research

169. Closing-in Behavior and Parietal Lobe Deficits: Three Single Cases Exhibiting Different Manifestations of the Same Behavior Full Text available with Trip Pro

and its association with frontal lobe dysfunction. We describe three patients in whom CIB was associated with posterior parietal deficits of different etiologies (stroke in Patient 1 and dementia in Patients 2 and 3). In copying figures, Patient 1 produced the shape with high accuracy but the rendering overlapped the model, while for Patients 2 and 3 the copies were distorted but overlapping or in close proximity to the target. In gesture imitation, Patient 2 performed the gestures toward (...) Closing-in Behavior and Parietal Lobe Deficits: Three Single Cases Exhibiting Different Manifestations of the Same Behavior Closing-in behavior (CIB) is observed in copying tasks (graphic or gestural) when the copy is performed near or on the top of the model. This symptom has been classically considered to be a manifestation of constructional apraxia and is often associated with a visuospatial impairment. More recent work emphasizes the attentional and/or executive nature of the behavior

2018 Frontiers in psychology

170. Predicting patterns of failure in temporal lobe GBMs: possible implications on radiotherapy treatment portals Full Text available with Trip Pro

); 5 adjacent regional sites (occipital lobe, inferior frontal lobe, caudate/thalamus/internal/external capsules, fornix/ventricular trigone), and 5 distant failure sites (ventricles, contralateral hemisphere, brainstem, leptomeninges and spine). Extension along major neuroanatomical pathways at initial presentation and at first documented Magnetic Resonance Imaging (MRI) failure were categorised into anterior, superior, medial and posterior pathways.Of the 100 patients, 86 had radiological (...) Predicting patterns of failure in temporal lobe GBMs: possible implications on radiotherapy treatment portals Characterise patterns of failure of Temporal Lobe (TL) Glioblastoma (GBM) following treatment with relation to normal temporal lobe anatomy and neural pathways.335 GBM patients received radiotherapy between 03/2007 and 07/2014, 100 were located in TL. Site of initial tumour and subsequent relapse were subdivided into 5 local TL sites (anterior, lateral, medial, posterior and superior

2018 Radiation oncology (London, England)

171. Revealing the Dynamic Modulations That Underpin a Resilient Neural Network for Semantic Cognition: An fMRI Investigation in Patients With Anterior Temporal Lobe Resection Full Text available with Trip Pro

that follow from ATL damage. To test these possibilities, 34 postsurgical temporal lobe epilepsy patients and 20 age-matched controls were scanned whilst completing semantic tasks. Pictorial tasks, which produced bilateral frontal and temporal activation, showed few activation differences between patients and control participants. Written word tasks, however, produced a left-lateralized activation pattern and greater differences between the groups. Patients with right ATL resection increased activation (...) Revealing the Dynamic Modulations That Underpin a Resilient Neural Network for Semantic Cognition: An fMRI Investigation in Patients With Anterior Temporal Lobe Resection One critical feature of any well-engineered system is its resilience to perturbation and minor damage. The purpose of the current study was to investigate how resilience is achieved in higher cognitive systems, which we explored through the domain of semantic cognition. Convergent evidence implicates the bilateral anterior

2018 Cerebral Cortex (New York, NY)

172. The anterior-ventrolateral temporal lobe contributes to boosting visual working memory capacity for items carrying semantic information Full Text available with Trip Pro

was significantly more efficient for famous faces, compared to unknown faces; (3) the right anterior-ventrolateral temporal lobe (ATL) causally mediated this superior WM storage for famous faces. Specifically, disrupting the ATL (a region tuned to semantic knowledge including person identity) selectively hinders WM accrual for celebrity faces while leaving the accrual for unfamiliar faces intact. Further, this 'semantically-accelerated' storage is impervious to disruption of the right middle frontal gyrus (...) The anterior-ventrolateral temporal lobe contributes to boosting visual working memory capacity for items carrying semantic information Working memory (WM) is a buffer that temporarily maintains information, be it visual or auditory, in an active state, caching its contents for online rehearsal or manipulation. How the brain enables long-term semantic knowledge to affect the WM buffer is a theoretically significant issue awaiting further investigation. In the present study, we capitalise

2018 NeuroImage

173. Disrupted dynamic network reconfiguration of the language system in temporal lobe epilepsy. Full Text available with Trip Pro

regions into four subsystems (i.e. bilateral frontal and temporal), we observed regional specialization in both the probability of transient interactions and the frequency of such changes, in both healthy controls and patients during task performance but not rest. Furthermore, we found that both left and right temporal lobe epilepsy patients displayed reduced interactions within the left frontal 'core' subsystem compared to the healthy controls, while left temporal lobe epilepsy patients were unique (...) Disrupted dynamic network reconfiguration of the language system in temporal lobe epilepsy. Temporal lobe epilepsy tends to reshape the language system causing maladaptive reorganization that can be characterized by task-based functional MRI, and eventually can contribute to surgical decision making processes. However, the dynamic interacting nature of the brain as a complex system is often neglected, with many studies treating the language system as a static monolithic structure. Here, we

2018 Brain

174. Does bilingualism increase brain or cognitive reserve in patients with temporal lobe epilepsy? Full Text available with Trip Pro

patients performed worse than HC on TMT-B. In addition, differences in group means between bilingual and monolingual patients on TMT-B approached significance when controlling for the extent of WM damage (P = .071; d = 0.62), suggesting a tendency toward higher performance for bilingual patients.Despite poorer integrity of regional frontal lobe WM, bilingual patients performed similarly to monolingual patients and HC on EF measures. These findings align with studies suggesting that bilingualism may (...) Does bilingualism increase brain or cognitive reserve in patients with temporal lobe epilepsy? Bilingual healthy adults have been shown to exhibit an advantage in executive functioning (EF) that is associated with microstructural changes in white matter (WM) networks. Patients with temporal lobe epilepsy (TLE) often show EF deficits that are associated with WM compromise. In this study, we investigate whether bilingualism can increase cognitive reserve and/or brain reserve in bilingual patients

2018 Epilepsia

175. Temporal lobe thickness and verbal memory in first-degree relatives of individuals with schizophrenia. Full Text available with Trip Pro

Temporal lobe thickness and verbal memory in first-degree relatives of individuals with schizophrenia. Cortical thinning in frontal and temporal regions has been reported in individuals diagnosed with schizophrenia and, less consistently, among their unaffected first-degree relatives. Likewise, first-degree relatives demonstrate attenuated differences in neurocognitive performance relative to healthy controls, indicating that neurocognitive performance may be an important endophenotype (...) of the disorder. Less is known about how cortical thickness relates to neurocognitive performance in these individuals. Given the robust nature of temporal structural abnormalities in schizophrenia, this study aimed to identify how temporal lobe cortical thickness might relate to verbal memory in first-degree relatives. Unaffected parents and siblings of individuals with adult-onset schizophrenia (N=62) and individuals in healthy control families (N=70) participating in the UCLA Family Study received

2018 Schizophrenia Research

176. Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat Full Text available with Trip Pro

into the cranial vault affecting predominantly the right frontal lobe and temporal lobe. Histopathological examination of the tumour revealed a histiocytic sarcoma.This is the first report of a cat with clinical signs of temporal lobe epilepsy due to an invasive, histiocytic sarcoma. Histiocytic sarcoma, although rare, should be included in the list of differential diagnoses for soft tissue masses extending through the cribriform plate. Other differential diagnoses are primary nasal neoplasia (eg (...) Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat A 10-year-old neutered female domestic shorthair cat was presented with an acute onset of neurological signs suggestive of a right-sided forebrain lesion, temporal lobe epilepsy and generalised seizure activity. MRI of the head revealed an expansile soft tissue mass in the caudal nasal passages (both sides but predominantly right-sided) involving the ethmoid bone and extending through the cribriform plate

2018 JFMS Open Reports

177. Frontal Lobe Syndromes (Treatment)

Frontal Lobe Syndromes (Treatment) Frontal Lobe Syndromes Treatment & Management: Medical Care, Consultations, Activity Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEzNTg2Ni10cmVhdG1lbnQ= processing > Frontal (...) Lobe Syndromes Treatment & Management Updated: Jun 08, 2018 Author: Stephen L Nelson, Jr, MD, PhD, FAACPDM, FAAN, FAAP; Chief Editor: Jasvinder Chawla, MD, MBA Share Email Print Feedback Close Sections Sections Frontal Lobe Syndromes Treatment Medical Care Medical care depends entirely on the pathology present. Physical and occupational therapy remain an important cornerstone of motor symptom management in FTD. Speech therapy may also help patients manage symptoms associated with aphasia, apraxia

2014 eMedicine.com

178. Frontal and Temporal Lobe Dementia (Treatment)

Frontal and Temporal Lobe Dementia (Treatment) Frontotemporal Dementia and Frontotemporal Lobar Degeneration: Overview, Etiology, Genetic Distribution and Variation Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) topographic relationships, and similar disorders. (See the image below.) Hematoxylin and eosin stain of the left frontal cortex from a patient with primary progressive aphasia. This shows loss of neurons, plump astrocytes (arrow), and microvacuolation of the superficial cortical layers. Reproduced with permission of John Wiley & Sons, Inc. In England and Europe, cases of frontal lobe dementia were described with progressive dysfunction of the frontal lobes. In a series of case reports, Neary and Snowden

2014 eMedicine.com

179. Frontal Lobe Epilepsy (Treatment)

Frontal Lobe Epilepsy (Treatment) Frontal Lobe Epilepsy Treatment & Management: Approach Considerations, Anti-Seizure Medications, Resective Surgery Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTE4NDA3Ni10cmVhdG1lbnQ= processing > Frontal Lobe Epilepsy Treatment & Management Updated: Sep 25, 2018 Author: Jillian L Rosengard, MD; Chief Editor: Selim R Benbadis, MD Share Email Print Feedback Close Sections Sections Frontal Lobe Epilepsy Treatment Approach Considerations While a first seizure may not be treated, anti-seizure medications should be initiated once the diagnosis of epilepsy is established. Many nocturnal episodes with prominent motor manifestations respond extremely well to carbamazepine

2014 eMedicine.com

180. Frontal and Temporal Lobe Dementia (Overview)

Frontal and Temporal Lobe Dementia (Overview) Frontotemporal Dementia and Frontotemporal Lobar Degeneration: Overview, Etiology, Genetic Distribution and Variation Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) topographic relationships, and similar disorders. (See the image below.) Hematoxylin and eosin stain of the left frontal cortex from a patient with primary progressive aphasia. This shows loss of neurons, plump astrocytes (arrow), and microvacuolation of the superficial cortical layers. Reproduced with permission of John Wiley & Sons, Inc. In England and Europe, cases of frontal lobe dementia were described with progressive dysfunction of the frontal lobes. In a series of case reports, Neary and Snowden

2014 eMedicine.com

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