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Frontal Lobe

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141. Cerebral Hemodynamics in Speech-Related Cortical Areas: Articulation Learning Involves the Inferior Frontal Gyrus, Ventral Sensory-Motor Cortex, and Parietal-Temporal Sylvian Area Full Text available with Trip Pro

, including the precentral and postcentral gyri, (iii) the opercular part of the inferior frontal gyrus (IFGoperc), (iv) the temporal cortex, including the superior temporal gyrus, and (v) the inferior parietal lobe (IPL), including the supramarginal and angular gyri. The posterior Sylvian fissure at the parietal-temporal boundary (area Spt) was selectively activated in the modified session. Furthermore, hemodynamic activity in the IFGoperc and vSMC was increased in the final half of the modified session (...) Cerebral Hemodynamics in Speech-Related Cortical Areas: Articulation Learning Involves the Inferior Frontal Gyrus, Ventral Sensory-Motor Cortex, and Parietal-Temporal Sylvian Area Although motor training programs have been applied to childhood apraxia of speech (AOS), the neural mechanisms of articulation learning are not well understood. To this aim, we recorded cerebral hemodynamic activity in the left hemisphere of healthy subjects (n = 15) during articulation learning. We used near-infrared

2018 Frontiers in neurology

142. Photobiomodulation Improves the Frontal Cognitive Function of Older Adults. Full Text available with Trip Pro

Photobiomodulation Improves the Frontal Cognitive Function of Older Adults. The frontal lobe hypothesis of age-related cognitive decline suggests that the deterioration of the prefrontal cortical regions that occurs with aging leads to executive function deficits. Photobiomodulation (PBM) is a newly developed, noninvasive technique for enhancing brain function, which has shown promising effects on cognitive function in both animals and humans. This randomized, sham-controlled study sought (...) to examine the effects of PBM on the frontal brain function of older adults.Thirty older adults without a neuropsychiatric history performed cognitive tests of frontal function (ie, the Eriksen flanker and category fluency tests) before and after a single 7.5-minute session of real or sham PBM. The PBM device consisted of three separate light-emitting diode cluster heads (633 and 870 nm), which were applied to both sides of the forehead and posterior midline, and delivered a total energy of 1349

2018 International Journal of Geriatric Psychiatry Controlled trial quality: uncertain

143. Frontal lobe function in temporal lobe epilepsy Full Text available with Trip Pro

Frontal lobe function in temporal lobe epilepsy Temporal lobe epilepsy (TLE) is typically associated with long-term memory dysfunction. The frontal lobes support high-level cognition comprising executive skills and working memory that is vital for daily life functioning. Deficits in these functions have been increasingly reported in TLE. Evidence from both the neuropsychological and neuroimaging literature suggests both executive function and working memory are compromised in the presence (...) and seizure spread is likely to have considerable bearing upon the cognitive phenotype and trajectory in TLE. The identification of the nature of frontal lobe dysfunction in TLE thus has important clinical implications for prognosis and surgical management. Longitudinal neuropsychological and neuroimaging studies assessing frontal lobe function in TLE patients pre- and postoperatively will improve our understanding further.Copyright © 2011 Elsevier B.V. All rights reserved.

2012 Epilepsy research

144. Bilateral white matter abnormality in children with frontal lobe epilepsy. Full Text available with Trip Pro

Bilateral white matter abnormality in children with frontal lobe epilepsy. In frontal lobe epilepsy (FLE), interictal discharges and seizures are more likely to spread to contralateral hemisphere and become secondarily generalized. The aim of this study was to assess white matter (WM) integrity in children with FLE using diffusion tensor imaging (DTI). Children with FLE and normal MRI, and healthy controls with no neurological or psychiatric disorders underwent DTI on 3T MRI. Whole brain

2014 Epilepsy research

145. Distinct frontal lobe morphology in girls and boys with ADHD Full Text available with Trip Pro

Distinct frontal lobe morphology in girls and boys with ADHD This study investigated whether frontal lobe cortical morphology differs for boys and girls with ADHD (ages 8-12 years) in comparison to typically developing (TD) peers.Participants included 226 children between the ages of 8-12 including 93 children with ADHD (29 girls) and 133 TD children (42 girls) for which 3T MPRAGE MRI scans were obtained. A fully automated frontal lobe atlas was used to generate functionally distinct frontal (...) girls and boys with ADHD.These results elucidate sex-based differences in cortical morphology of functional subdivisions of the frontal lobe and provide additional evidence of associations among SA and symptom severity in children with ADHD.

2014 NeuroImage : Clinical

146. Solitary Langerhans cell histiocytosis of frontal lobe: a case report and literature review Full Text available with Trip Pro

Solitary Langerhans cell histiocytosis of frontal lobe: a case report and literature review The brain parenchymal Langerhans cell histiocytosis (LCH) without systemic disease or lytic skull lesions is extremely rare. We report a 23-year-old male presenting with new onset 1 hour seizure with loss of consciousness 20 days prior to admission, and recurrent seizure 2 weeks later. Brain magnetic resonance imaging (MRI) showed an irregularly mass with enhancement involving the right frontal lobe

2014 Chinese Journal of Cancer Research

147. Patient-specific connectivity pattern of epileptic network in frontal lobe epilepsy Full Text available with Trip Pro

Patient-specific connectivity pattern of epileptic network in frontal lobe epilepsy There is evidence that focal epilepsy may involve the dysfunction of a brain network in addition to the focal region. To delineate the characteristics of this epileptic network, we collected EEG/fMRI data from 23 patients with frontal lobe epilepsy. For each patient, EEG/fMRI analysis was first performed to determine the BOLD response to epileptic spikes. The maximum activation cluster in the frontal lobe

2014 NeuroImage : Clinical

148. Frontal Lobe Lipoma Associated with Cortical Dysplasia and Abnormal Vasculature Full Text available with Trip Pro

Frontal Lobe Lipoma Associated with Cortical Dysplasia and Abnormal Vasculature Intracranial lipomas (ICLs) are rare lesions, the vast majority encountered as incidental findings on imaging studies. ICLs are generally pericallosal midline lesions and thought to be asymptomatic and can be accompanied by additional intracranial congenital malformations. We describe a 17-year old male with an unusual case of ICL on the frontal lobe associated with cortical dysplasia and abnormal vasculature

2014 The neuroradiology journal

149. Alterations in the Functional Connectivity of Frontal Lobe Networks Preceding Emergence Delirium in Children. Full Text available with Trip Pro

Alterations in the Functional Connectivity of Frontal Lobe Networks Preceding Emergence Delirium in Children. This study aimed to characterize the electroencephalogram in children who emerged with emergence delirium (ED) compared with children without ED using methods that involved the assessment of cortical functional connectivity.Children aged 5 to 15 yr had multichannel electroencephalographic recordings during induction and emergence from anesthesia during minor surgical procedures (...) frequency activity (referred to as an indeterminate state). In children with ED, arousal with delirious behavior and a variety of electroencephalogram patterns occurred during the indeterminate state, before the appearance of normal wake or sleep patterns. The electroencephalogram in children without ED progressed from the indeterminate state to classifiable sleep or drowsy states, before peaceful awakening. Statistically significant differences in frontal lobe functional connectivity were identified

2014 Anesthesiology

150. External carotid artery flow maintains near infrared spectroscopy-determined frontal lobe oxygenation during ephedrine administration. Full Text available with Trip Pro

External carotid artery flow maintains near infrared spectroscopy-determined frontal lobe oxygenation during ephedrine administration. Phenylephrine and ephedrine affect frontal lobe oxygenation ([Formula: see text]) differently when assessed by spatially resolved near infrared spectroscopy. We evaluated the effect of phenylephrine and ephedrine on extra- vs intra-cerebral blood flow and on [Formula: see text].In 10 healthy males (age 20-54 yr), phenylephrine or ephedrine was infused for an ∼20

2014 British Journal of Anaesthesia

151. Neuroimaging and neurodevelopmental outcome of preterm infants with a periventricular haemorrhagic infarction located in the temporal or frontal lobe. (Abstract)

Neuroimaging and neurodevelopmental outcome of preterm infants with a periventricular haemorrhagic infarction located in the temporal or frontal lobe. The aim of the study was to compare clinical and neuroimaging characteristics and neurodevelopmental outcome in preterm infants with a periventricular haemorrhagic infarction (PVHI) located in the temporal or frontal periventricular white matter.The study was a retrospective hospital-based study of preterm infants with a frontal PVHI (n=21; 11 (...) was noted in seven infants with a frontal PVHI and five with a temporal PVHI. There were more infants with a temporal PVHI who developed visual impairment (n=5) or behavioural problems (n=7) compared with those with a frontal PVHI (visual impairment (n=2), behavioural problems (n=3).PVHI located in the temporal or frontal lobe is almost invariably related to a typical motor outcome, but carries a risk of cognitive, behavioural, and visual problems, especially in infants with a PVHI located

2014 Developmental Medicine and Child Neurology

152. A decrease in spatially resolved near-infrared spectroscopy-determined frontal lobe tissue oxygenation by phenylephrine reflects reduced skin blood flow. Full Text available with Trip Pro

A decrease in spatially resolved near-infrared spectroscopy-determined frontal lobe tissue oxygenation by phenylephrine reflects reduced skin blood flow. Spatially resolved near-infrared spectroscopy-determined frontal lobe tissue oxygenation (ScO2) is reduced with administration of phenylephrine, while cerebral blood flow may remain unaffected. We hypothesized that extracranial vasoconstriction explains the effect of phenylephrine on ScO2.We measured ScO2 and internal and external carotid

2014 Anesthesia and Analgesia

153. Simultaneous subdural and scalp EEG correlates of frontal lobe epileptic sources. (Abstract)

Simultaneous subdural and scalp EEG correlates of frontal lobe epileptic sources. To assess the visibility and detectability in scalp electroencephalography (EEG) of cortical sources in frontal lobe epilepsy (FLE) as to their localization, and the extent and amplitude of activation.We analyzed the simultaneous subdural and scalp interictal EEG recordings of 14 patients with refractory frontal lobe epilepsy (FLE) associated with focal cortical dysplasia. Subdural spike types were identified (...) frontal, two in the dorsolateral gyri, two in the depth of dorsolateral sulci, and two in the basal frontal region. Cortical sources generating scalp-detectable spikes presented a median of 6 cm(2) of activated cortical convexity surface and a subdural spike-to-background-amplitude ratio >8. These sources were associated with a higher number of activated subdural grid contacts and a higher subdural spike-to-background amplitude ratio than sources generating non-scalp-detectable spikes.Not only

2014 Epilepsia

154. Diagnosing frontal lobe epilepsy in the ED. (Abstract)

Diagnosing frontal lobe epilepsy in the ED. Frontal lobe seizures are a common form of epilepsy. It has a variable presentation and can often be missed in the emergency department (ED). Missing this diagnosis can lead to a delay in treatment and poor outcome for cognitive function. We hereby present a case of a 14-year-old girl who presented to our ED after the development of abnormal movements. Knowledge of the anatomy behind the development of partial seizures and the best testing modality (...) can aid in the diagnosis. In this review, we attempt to discuss the pathophysiology of frontal lobe epilepsy and what physical examination findings and testing will best lead to a diagnosis.

2014 American Journal of Emergency Medicine

155. DEPDC5 mutations in families presenting as autosomal dominant nocturnal frontal lobe epilepsy. (Abstract)

DEPDC5 mutations in families presenting as autosomal dominant nocturnal frontal lobe epilepsy. To study the prevalence of DEPDC5 mutations in a series of 30 small European families with a phenotype compatible with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE).Thirty unrelated families referred with ADNFLE were recruited in France, Italy, Germany, Belgium, and Norway. Whole-exome sequencing was performed in 10 probands and direct sequencing of the DEPDC5 coding sequence in 20

2014 Neurology

156. Intravenous or local injections of flavoxate into the rostral pontine reticular formation inhibit urinary frequency induced by activation of medial frontal lobe neurons in rats. (Abstract)

Intravenous or local injections of flavoxate into the rostral pontine reticular formation inhibit urinary frequency induced by activation of medial frontal lobe neurons in rats. The rostral pontine reticular formation has a strong inhibitory effect on micturition by facilitating lumbosacral glycinergic neurons. We assessed the influence of the rostral pontine reticular formation on the micturition reflex after noradrenaline injection in the medial frontal lobe. We also examined the relation (...) between the medial frontal lobe and the rostral pontine reticular formation.Continuous cystometry was performed in 28 female rats. After the interval between bladder contractions was shortened by noradrenaline injection in the medial frontal lobe we injected glutamate or flavoxate hydrochloride in the rostral pontine reticular formation or intravenously injected flavoxate or propiverine. The change in bladder activity was examined.Noradrenaline injection in the medial frontal lobe shortened

2014 Journal of Urology

157. Relationships of Behavioral Measures of Frontal Lobe Dysfunction with Underlying Electrophysiology in Cocaine-Dependent Patients Full Text available with Trip Pro

Relationships of Behavioral Measures of Frontal Lobe Dysfunction with Underlying Electrophysiology in Cocaine-Dependent Patients Despite evidence that frontal lobe functioning is impaired in cocaine-dependent individuals, relationships between behavioral measures of frontal dysfunction and electrophysiological measures of inhibition in cocaine use have not been explored.Using the Frontal Systems Behavior Scale (FrSBe), frontal dysfunction was assessed in a group of abstinent cocaine-dependent (...) scores in the patients.Relationships between FrSBe scores and TMS-based measures highlight neurophysiological aberrations underlying frontal lobe dysfunction in cocaine abusers. TMS and EP measures may be useful probes of the intermediary steps between frontal lobe dysfunction and addictive behavior.© American Academy of Addiction Psychiatry.

2014 The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions

158. Recent seizure activity alters motor organization in frontal lobe epilepsy as revealed by task-based fMRI. (Abstract)

Recent seizure activity alters motor organization in frontal lobe epilepsy as revealed by task-based fMRI. Patients with frontal lobe epilepsy (FLE) commonly demonstrate motor impairments, suggesting that frontal lobe seizures affect motor function. However, the underlying mechanisms of these deficits are not known, nor has any study systematically examined motor organization in these patients. We therefore examined cortical motor organization in a group of adult patients with FLE, using task

2014 Epilepsy research Controlled trial quality: uncertain

159. Hemichorea and dystonia due to frontal lobe meningioma Full Text available with Trip Pro

Hemichorea and dystonia due to frontal lobe meningioma Tumors originating from the meninges, also known as meningiomas, have rarely been known to cause parkinsonian symptoms and other movement disorders. Although some cases of AV malformations causing movement disorders have been described in the literature, not much has been reported about meningiomas in this regard. The aim of this case report is to further highlight the importance of brain imaging in patients with movement disorders for even (...) a benign tumor; and also emphasize the need for a careful movement disorder examination because more than one phenomenology of movement disorders may result from the mechanical pressure caused by a tumor. We present a case report of a patient with a heavily calcified right frontal lobe meningioma. Our patient had irregular, involuntary, brief, fleeting and unpredictable movements of her left upper and lower extremities, consistent with chorea. The patient also had abnormal dystonic posturing of her

2014 Journal of neurosciences in rural practice

160. The Role of Semiology in the Work-Up of Frontal Lobe Epilepsy: In the Eye of the Beholder Full Text available with Trip Pro

The Role of Semiology in the Work-Up of Frontal Lobe Epilepsy: In the Eye of the Beholder 25170315 2014 08 29 2018 11 13 1535-7597 14 4 2014 Jul Epilepsy currents Epilepsy Curr The role of semiology in the work-up of frontal lobe epilepsy: in the eye of the beholder. 194-5 10.5698/1535-7597-14.4.194 Jehi Lara E LE eng Journal Article United States Epilepsy Curr 101135954 1535-7511 2014 8 30 6 0 2014 8 30 6 0 2014 8 30 6 1 ppublish 25170315 10.5698/1535-7597-14.4.194 PMC4120387 Epilepsy Behav

2014 Epilepsy Currents

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