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Friable Cervix

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1. Friable Cervix

Friable Cervix Friable Cervix Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Friable Cervix Friable Cervix Aka: Friable Cervix (...) , Cervical bleeding From Related Chapters II. Labs screen III. Management Pressure with swab stick Monsel's Solution Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Friable Cervix." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Cervical Disorders About FPnotebook.com is a rapid access, point-of-care medical reference for primary care

2018 FP Notebook

2. Friable Cervix

Friable Cervix Friable Cervix Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Friable Cervix Friable Cervix Aka: Friable Cervix (...) , Cervical bleeding From Related Chapters II. Labs screen III. Management Pressure with swab stick Monsel's Solution Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Friable Cervix." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Cervical Disorders About FPnotebook.com is a rapid access, point-of-care medical reference for primary care

2015 FP Notebook

3. Adenoid cystic carcinoma of cervix: two cases report and review of the literature (PubMed)

-old woman presented with vaginal bleeding with pelvic pain. Physical examination revealed a friable mass in the cervix. Incisional biopsy was performed. In the both cases the diagnosis of adenoid cystic carcinoma of the cercix was confirmed. Adenoid cystic carcinoma of the cervix is clinically and radiologically similar to other tumors of the cervix but the diagnosis can only be made by histological examination. (...) Adenoid cystic carcinoma of cervix: two cases report and review of the literature Adenoid cystic carcinoma of the cervix is a rare and aggressive tumor with fatal outcome. In this paper we report two cases of primary adenoid cystic carcinoma and a review of literature. A 80 years old woman, admitted to our hospital with postmenopausal bleeding and hydrorrhea. Gynealogical examination showed a cervical stenotic with the presence of a tumor processus. Biopsy of cervical growth was done. 80-year

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2015 The Pan African medical journal

4. Lymphoma of the Cervix (PubMed)

Lymphoma of the Cervix Primary non-Hodgkins lymphoma of the uterine cervix is a very rare diagnosis. A 54-year-old woman presented with a 3-month history of postmenopausal bleeding per vaginum. On examination, a friable, fungating lesion was seen on the cervix. Histology revealed a CD 20 positive high-grade non-Hodgkin's diffuse large B cell lymphoma from cervical biopsies and endometrial curettage. She was diagnosed as stage IE after workup and subsequently treated with six cycles of R-CHOP

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2012 Case reports in hematology

5. Genital tract chlamydia infection

chlamydia infections can lead to more serious problems such as pelvic inflammatory disease (PID), ectopic pregnancy, and infertility in women, and epididymitis and prostatitis in men. History and exam presence of risk factors asymptomatic cervical discharge friable cervix abnormal vaginal bleeding penile discharge vaginal discharge dysuria pelvic pain fever/chills nausea/vomiting scrotal pain myalgias abdominal pain mucopurulent rectal discharge or tenesmus age under 25 years, sexually active new sex

2019 BMJ Best Practice

6. Vaginitis

., atrophic vaginitis). Bacterial vaginosis, trichomoniasis, and candidiasis are types of infections that cause vaginitis. History and exam presence of risk factors vaginal discharge dysuria discharge adherent to vaginal mucosa prior episodes pruritus vulvodynia vaginal dryness dyspareunia erythema pale epithelium shiny epithelium decreased elasticity friable epithelium fever vaginal bleeding abdominal pain strawberry cervix douching poor or excessive hygiene antibiotic use change in feminine hygiene

2018 BMJ Best Practice

7. Genital tract chlamydia infection

chlamydia infections can lead to more serious problems such as pelvic inflammatory disease (PID), ectopic pregnancy, and infertility in women, and epididymitis and prostatitis in men. History and exam presence of risk factors asymptomatic cervical discharge friable cervix abnormal vaginal bleeding penile discharge vaginal discharge dysuria pelvic pain fever/chills nausea/vomiting scrotal pain myalgias abdominal pain mucopurulent rectal discharge or tenesmus age under 25 years, sexually active new sex

2018 BMJ Best Practice

9. Immune Checkpoint Blockade in PD-L1-Positive Platinum-Refractory Cervical Carcinoma. (PubMed)

, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice. A 36-year-old white married mother of two small children presented with intermenstrual bleeding, dyspareunia, and pelvic pain. Because of significant lapses in health care coverage, she had had only sporadic screening for cervical cancer over the past 15 years. On evaluation with a vaginal speculum, her cervix was found to have been replaced by a friable lesion 5 cm in diameter. Biopsy revealed (...) poorly differentiated, squamous cell carcinoma. Bimanual pelvic and rectovaginal examination, as well as radiographic imaging studies, were consistent with an International Federation of Gynecology and Obstetrics (FIGO) stage IB3 squamous cell carcinoma of the cervix. She was treated with cisplatin-based chemoradiation (40 mg/m2 body surface area once per week with a planned total dose of 50 Gy using intensity modulated radiotherapy) plus high-dose-rate intracavitary brachytherapy (to bring the total

2019 Journal of Clinical Oncology

10. South Australian gynaecological cancer pathway

for assessing symptoms Types of symptoms • Intermenstrual bleeding (IMB) • Postcoital bleeding (PCB) • Postmenopausal bleeding (PMB) • Pelvic discomfort • Deep pelvic pain • Vaginal discharge • Dyspareunia • Unilateral leg oedema • Sciatica Findings to note • Abnormal looking/feeling ectocervix • Vaginal discharge • Contact bleeding from the cervix • Cervical tenderness • Cervix with friable tissue, ulceration or abnormal polyp • Other possible sites of bleeding • Cervical mass on palpation Patient History (...) population incidence, the other statistical divisions do not have a large enough sample size to clearly demonstrate trends in incidence. Table 1 - SA Gynaecological Cancer Incidence – whole State Year Cervix Uterine Uterine Ovary Vulva, vagina and other unspecified female genitalia Total 1999 66 144 122 27 359 2000 57 159 104 27 347 2001 47 148 92 31 318 2002 40 154 105 19 318 2003 45 165 84 26 320 2004 46 172 95 27 340 2005 56 170 93 34 353 2006 47 169 97 25 338 2007 42 161 108 30 341 2008 67 181 103 24

2014 Clinical Practice Guidelines Portal

12. Chlamydia - uncomplicated genital

or intermenstrual bleeding, purulent vaginal discharge, mucopurulent cervical discharge, deep dyspareunia, dysuria, pelvic pain and tenderness, inflamed or friable cervix. In men: dysuria, urethral discharge, urethral discomfort. Samples are taken by the following methods: In women: endocervical or vulvovaginal swab, or first-void urine sample. In men: first-void urine sample or urethral swab. Treatment should be initiated promptly in all people who test positive for chlamydia, or have symptoms or signs (...) chlamydia in sexually active women with: Increased vaginal discharge. Post-coital or intermenstrual bleeding. Purulent vaginal discharge. Mucopurulent cervical discharge. Deep dyspareunia. Dysuria. Pelvic pain and tenderness. Cervical motion tenderness. Inflamed or friable cervix (which may bleed on contact). Suspect chlamydia in sexually active men with: Dysuria. Mucoid or mucopurulent urethral discharge. Urethral discomfort/urethritis. Epididymo-orchitis. Reactive arthritis. Symptoms of rectal

2016 NICE Clinical Knowledge Summaries

13. A Rare Collision Tumour of Uterus- Squamous Cell Carcinoma and Endometrial Stromal Sarcoma (PubMed)

and a sarcoma. We report a case of a 60-year-old lady who presented with complaints of post-menopausal bleeding. A cervical biopsy was performed which showed a non-keratinizing squamous cell carcinoma of cervix. Intra-operatively the uterus was bulky with a 6 cm x 5 cm polypoidal mass in the endometrial canal along with a 2 cm friable cervical growth. The fleshy uterine cavity mass was a spindle cell tumour with moderate pleomorphism and frequent mitosis. It was immunopositive for CD10 and negative (...) for smooth muscle actin and cytokeratin 5/6. The other growth showed non-keratinizing squamous cell carcinoma which was positive for cytokeratin 5/6. Based on the distinct topographical location and limited areas of tumour admixture of the two tumours, a diagnosis of collision tumour of uterus comprising of endometrial stromal sarcoma (high grade) uterus and squamous cell carcinoma cervix was made.

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2017 Journal of clinical and diagnostic research : JCDR

14. Treatment and Recommendations for Homeless Patients with Chlamydial or Gonococcal Infections

: negative ? Pelvic exam: external genitals: no lesions; BSU (Bartholin’s gland, Skene’s gland, urethra): WNL; cervix: friable, copious amount of yellowish discharge, +CMT (cervical motion tenderness), no lesions; vagina: no lesions, pooled discharge; uterus: WNL; adnexa: mild tenderness on bi-manual exam, no palpable masses. ? Wet mount - WBCs >10 per high-powered field; RBCs: few; negative for trichomonas, clue cells. ? KOH: no yeast, negative whiff test. Assessment: Unremarkable clinical examination (...) with exception for pelvic exam. The cervix is friable and tender with palpation. Yellow, mucopurulent discharge noted draining from the os. There is mild adnexal pain, but no uterine pain with deep palpation. Pap smear obtained and swabs for gonorrhea and chlamydia collected. Diagnosis: Suspected pelvic inflammatory disease secondary to gonorrhea and/or chlamydia infection. Plan: Empiric oral treatment initiated for suspected PID with plan for patient to return to the clinic for re- examination in 72-hours

2013 National Health Care for the Homeless Council

15. Management of symptomatic vulvovaginal atrophy: 2013 position statement of The North American Menopause Society

and vaginal atrophic changes increase the likeli- hood of trauma, infection, and pain. Left untreated, severe VVA can result in a vaginal surface that is friable, with pe- techiae, ulcerations, and tears, accompanied in some cases by stenosis. Bleeding may occur from minimal trauma, such as speculum insertion. 12 On questioning, patients may ac- knowledge bleeding with intercourse and/or wiping. SymptomaticVVAmayoccurinhypoestrogenicstatesother thannaturalmenopause.Examplesincludesurgicalmenopause (...) become obliterated, making the cervix flush with the vault. Petechiae may be seen in the vestibule or vagina. With atrophic vaginitis, brown or yellow secretions may be present. With severe VVA, there may be such shortening of the vaginal vault and narrowing of the introitus that spec- uluminsertionandvisualinspectionofthevaginalvaultmay not be possible. Small pediatric speculums with lubrication may be helpful with severe atrophy. Although assessment of the vaginal maturation index (VMI) and vaginal

2013 The North American Menopause Society

16. Cervical cancer and HPV

discharge. Pelvic pain/dyspareunia. Rarely, women may present with advanced cancer with symptoms such as pelvic discomfort or pain, renal failure, leakage of urine or faeces from a fistula, lymphoedema, or severe haemorrhage. On examination: The cervix may appear inflamed or friable and bleed on contact (although the most likely cause for this will be infection with Chlamydia trachomatis ). There may be a visible ulcerating or fungating lesion, or a foul-smelling serosanguineous vaginal discharge (...) : The cervix may appear inflamed or friable and bleed on contact (although the most likely cause for this will be Chlamydia trachomatis. For more information, see the section on ). There may be a visible ulcerating or fungating lesion or a foul-smelling serosanguineous vaginal discharge. Basis for recommendation Basis for recommendation This information is based on the Scottish Intercollegiate Guidelines Network (SIGN) guideline Management of cervical cancer [ ], the British Medical Journal (BMJ) best

2014 NICE Clinical Knowledge Summaries

17. Management of genital Chlamydia trachomatis infection

in women. 72-74 Rectal infection in either men or women rarely causes signs or symptoms. 75 Chlamydial infection may present with right hypochondrial pain due to perihepatitis. 76 c t esting for chlamydia should be performed in women and men with any of the following symptoms and signs: women ? vaginal discharge - post-coital/intermenstrual/breakthrough bleeding - inflamed/friable cervix - (which may bleed on contact) urethritis - pelvic inflammatory disease - lower abdominal pain in the sexually (...) obtained by swabbing the cervix, vagina (clinician-obtained or patient-obtained), urethra, rectum or pharynx, and FVU. Most eligible studies evaluated FVU. In women this was usually compared to an endocervical swab and in men it was compared to a urethral swab. Two systematic reviews found that use of an endocervical swab gave greater sensitivity than a FVU with sPCR and bD Probetec. 18,19 The use of a vaginal swab or endocervical swab results in similar performance. 35 Clinician and patient-obtained

2009 SIGN

18. The role of endoscopy in patients with anorectal disorders

radiation. 6 Symptoms may include hematochezia, tenes- mus, diarrhea, and defecatory urgency, whereas the en- doscopic appearance ranges from diffuse, friable angioec- tatic lesions to frank ulceration. Approximately 95% of mild radiation-induced proctopathy is temporary and self- limited, and up to 5% of patients experience symptoms thatarerefractorytoconservativemanagement.Treatment of radiation proctopathy that is found incidentally on en- doscopyisnotusuallyindicatedunlesstherearesigns(eg, anemia (...) percent formalin for the treatment of radiation-induced hemorrhagic proctitis. Dis Colon Rectum2007;50:213-7. 38. Saclarides TJ, King DG, Franklin JL, et al. Formalin instillation for refrac- toryradiation-inducedhemorrhagicproctitis.Reportof16patients.Dis ColonRectum1996;39:196-9. 39. Yegappan M, Ho YH, Nyam D, et al. The surgical management of colo- rectal complications from irradiation for carcinoma of the cervix. Ann AcadMedSingapore1998;27:627-30. 40. ParikhS,HughesC,SalvatiEP

2010 American Society for Gastrointestinal Endoscopy

19. Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis

examination (Ulcers, granulation, friable mucosa on rigid nasendoscopy. Excluding crusting) Inflammation on flexible laryngoscopy (Ulcers, granulation, friable mucosa in the larynx) Inflamed TM*/middle ear (Persistent inflammation or granulation tissue in tympanic membrane/middle ear) Sudden sensorineural hearing loss (30db drop in 3 frequencies within 72 hours) Other ENT/upper airway manifestations of active GPA observed during structured ENT exam including but not limited to lacrimal gland (...) of adequately treated basal or squamous cell carcinoma of the skin or carcinoma in situ of the cervix. History of psychiatric disorder. At the Investigator's discretion, receipt of a live vaccine within 4 weeks prior to randomization. Positive hepatitis B or C serology is considered a potential exclusion criterion. Hepatitis B screening should include hepatitis B surface antigen (HBsAg) and core antibody (anti-HBc) in all patients. For patients who show evidence of prior hepatitis B infection (HBsAg

2015 Clinical Trials

20. The Use of Proton Pump Inhibitor on the Prevention of Gastric Cancer Bleeding

Detailed Description: Tumor bleeding frequently occurs in inoperable gastric cancer patients. Inoperable gastric cancer usually has a large ulcer with friable tumor vessels. Acidic environment in stomach prevents adequate function of coagulation cascade and decrease clot stability. Gastric cancer bleeding may cause significant morbidity and often delays scheduled chemotherapy. National Center Center data showed that about 30% of gastric cancer patient undergoing palliative chemotherapy eventually (...) or carcinoma in situ of the cervix Patients with significant or uncontrolled gastrointestinal bleeding in the past two weeks without evidence of resolution documented by endoscopy or colonoscopy Previous subtotal gastrectomy or total gastrectomy Patient with a plan for neo-adjuvant chemotherapy Lack of physical integrity of the upper gastrointestinal tract or malabsorption syndrome, or inability to take oral medication Allergy history to proton pump inhibitor Serious concurrent infection or nonmalignant

2014 Clinical Trials

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