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Fluoxetine

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181. Sleep disturbance as detected by actigraphy in pre-pubertal juvenile monkeys receiving therapeutic doses of fluoxetine Full Text available with Trip Pro

Sleep disturbance as detected by actigraphy in pre-pubertal juvenile monkeys receiving therapeutic doses of fluoxetine Sleep disturbance is a reported side effect of antidepressant drugs in children. Using a nonhuman primate model of childhood selective serotonin reuptake inhibitor (SSRI) therapy, sleep was studied quantitatively with actigraphy. Two 48-h sessions were recorded in the home cage environment of juvenile male rhesus monkeys at two and three years of age, after one and two years (...) of treatment with a therapeutic dose of the SSRI fluoxetine, and compared to vehicle treated controls. A third session was conducted one year after discontinuation of treatment at four years of age. During treatment, the fluoxetine group demonstrated sleep fragmentation as indexed by a greater number of rest-activity transitions compared to controls. In addition fluoxetine led to more inactivity during the day as indexed by longer duration of rest periods and the reduced activity during these periods

2016 Neurotoxicology and teratology

182. Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Fluoxetine Tablets Under Fed Conditions

Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Fluoxetine Tablets Under Fed Conditions Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Fluoxetine Tablets Under Fed Conditions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Fluoxetine Tablets Under Fed Conditions The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02965274 Recruitment Status : Completed First Posted : November 16, 2016 Last Update Posted : November 16, 2016 Sponsor

2016 Clinical Trials

183. Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Fluoxetine Tablet Under Fasting Conditions

Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Fluoxetine Tablet Under Fasting Conditions Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Fluoxetine Tablet Under Fasting Conditions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Fluoxetine Tablet Under Fasting Conditions The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02965261 Recruitment Status : Completed First Posted : November 16, 2016 Last Update Posted : November 16, 2016

2016 Clinical Trials

184. Efficacy of Fluoxetine

Efficacy of Fluoxetine Efficacy of Fluoxetine - a Trial in Stroke - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Efficacy of Fluoxetine - a Trial in Stroke (EFFECTS) The safety and scientific validity (...) Foundation Stroke-Riksförbundet Konung Gustaf V:s och Drottning Victorias Frimurarestiftelse Hjärnfonden (The Swedish Brain foundation) The Swedish Medical Association Information provided by (Responsible Party): Erik Lundström, MD, PhD, Karolinska Institutet Study Details Study Description Go to Brief Summary: The purpose of this study is to investigate whether routine administration of fluoxetine 20mg once daily in the 6 months initiated during the acute stroke improves the patient's functional outcome

2016 Clinical Trials

185. Do you have any updated advice on the use of antidepressants in pregnancy ( esp fluoxetine) and advice on which SSRI is best to use when the mother is breast feeding.

Do you have any updated advice on the use of antidepressants in pregnancy ( esp fluoxetine) and advice on which SSRI is best to use when the mother is breast feeding. Do you have any updated advice on the use of antidepressants in pregnancy ( esp fluoxetine) and advice on which SSRI is best to use when the mother is breast feeding. - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only (...) of antidepressants in pregnancy ( esp fluoxetine) and advice on which SSRI is best to use when the mother is breast feeding. ATTRACT answered a question in 2013 on antidepressants in pregnancy (1) and no relevant secondary evidence has been identified since this was published. The answer is available at the URL given in reference 1 below. On breastfeeding, the most recent advice identified is a CKS guidance on antenatal and postnatal depression (2) which includes a section on choice of antidepressants in breast

2014 TRIP Answers

186. Effect of using fluoxetine at different time windows on neurological functional prognosis after ischemic stroke. (Abstract)

Effect of using fluoxetine at different time windows on neurological functional prognosis after ischemic stroke. To evaluate the effect of using fluoxetine at different time intervals after ischemic stroke on neurological functional prognosis in China.The patients enrolled were randomly allocated to three groups. Group A received fluoxetine 20 mg/day immediately; group B received fluoxetine 20 mg/day 7 days after enrollment; and group C did not receive fluoxetine. The therapeutic duration (...) of fluoxetine was 90 days and the follow-up period was 180 days.The mean NIHSS score at day 90 was significantly lower in group A than group C (P = 0.005), while at day 180, the mean score in group A was significantly lower than groups B and C (P = 0.035, P = 0.000), respectively. The mean BI score at day 90 was significantly higher in group A than group C (P = 0.001), while at day 180, the mean score in group A was significantly higher than groups B and C (P = 0.036, P = 0.000), respectively. Regression

2016 Restorative neurology and neuroscience Controlled trial quality: uncertain

187. Combination of CBT with fluoxetine works better for obsessive-compulsive disorder. (Abstract)

Combination of CBT with fluoxetine works better for obsessive-compulsive disorder. 26878959 2016 12 13 2018 12 02 1876-2026 5 1 2012 Mar Asian journal of psychiatry Asian J Psychiatr Combination of CBT with fluoxetine works better for obsessive-compulsive disorder. 113 10.1016/j.ajp.2011.11.013 Giasuddin Noor Ahmed NA Department of Psychiatry, Faridpur Medical College, Faridpur, Bangladesh. Nahar Jhunu Shamsun JS Department of Psychiatry, BSM Medical University, Dhaka, Bangladesh. Morshed Nahid (...) Mahjabin NM Balhara Yatan Pal Singh YP Lady Hardinge Medical College, New Delhi 110001, India. eng Letter Randomized Controlled Trial 2011 12 23 Netherlands Asian J Psychiatr 101517820 1876-2018 0 Serotonin Uptake Inhibitors 01K63SUP8D Fluoxetine IM Adult Cognitive Behavioral Therapy methods Combined Modality Therapy Female Fluoxetine therapeutic use Humans Male Obsessive-Compulsive Disorder therapy Serotonin Uptake Inhibitors therapeutic use Treatment Outcome Young Adult 2011 10 24 2011 11 30 2016 2

2016 Asian Journal of Psychiatry Controlled trial quality: uncertain

188. Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD)

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD) Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details

2016 Clinical Trials

189. Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 7 to 11 Years With Major Depressive Disorder (MDD)

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 7 to 11 Years With Major Depressive Disorder (MDD) Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 7 to 11 Years With Major Depressive Disorder (MDD) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 7 to 11 Years With Major Depressive Disorder (MDD) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your

2016 Clinical Trials

190. Fluoxetine for Visual Recovery After Ischemic Stroke

Fluoxetine for Visual Recovery After Ischemic Stroke Fluoxetine for Visual Recovery After Ischemic Stroke - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Fluoxetine for Visual Recovery After Ischemic Stroke (...) by (Responsible Party): Bogachan Sahin, University of Rochester Study Details Study Description Go to Brief Summary: The purpose of this study is to determine whether fluoxetine, a selective serotonin reuptake inhibitor commonly used for depression, enhances visual recovery after an acute ischemic stroke. Condition or disease Intervention/treatment Phase Acute Stroke Visual Field Loss Drug: Fluoxetine Drug: Placebo Phase 2 Study Design Go to Layout table for study information Study Type : Interventional

2016 Clinical Trials

191. Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity

Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity (Metfluo) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03051451 Recruitment Status : Suspended (Business decision) First Posted : February 13, 2017 Last Update Posted

2016 Clinical Trials

192. Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment. Full Text available with Trip Pro

Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment. It has been hypothesized that selective serotonin reuptake inhibitors (SSRIs), the most common treatment for major depression, affect mood through changes in immune function. However, the effects of SSRIs on inflammatory response are contradictory since these act either as anti- or pro-inflammatory drugs. Previous experimental and clinical studies showed (...) that the quality of the living environment moderates the outcome of antidepressant treatment. Therefore, we hypothesized that the interplay between SSRIs and the environment may, at least partially, explain the apparent incongruence regarding the effects of SSRI treatment on the inflammatory response. In order to investigate such interplay, we exposed C57BL/6 mice to chronic stress to induce a depression-like phenotype and, subsequently, to fluoxetine treatment or vehicle (21days) while being exposed to either

2016 Brain, behavior, and immunity

193. Augmenting Cognitive Behavior Therapy for School Refusal with Fluoxetine: A Randomized Controlled Trial. (Abstract)

Augmenting Cognitive Behavior Therapy for School Refusal with Fluoxetine: A Randomized Controlled Trial. This study investigates whether the augmentation of cognitive behavior therapy (CBT) with fluoxetine improves outcomes in anxious school refusing adolescents (11-16.5 years). Sixty-two participants were randomly allocated to CBT alone, CBT + fluoxetine or CBT + placebo. All treatments were well tolerated; with one suicide-attempt in the CBT + placebo group. All groups improved significantly (...) in the CBT + fluoxetine group than the CBT alone group. These results indicate the chronicity of school refusal, and the need for future research into how to best improve school attendance rates.

2016 Child psychiatry and human development Controlled trial quality: uncertain

194. Synergistic Effect of Azoles and Fluoxetine against Resistant Candida albicans Attributed to Attenuating Fungal Virulence. Full Text available with Trip Pro

Synergistic Effect of Azoles and Fluoxetine against Resistant Candida albicans Attributed to Attenuating Fungal Virulence. This study evaluated the synergistic effects of the selective serotonin reuptake inhibitor, fluoxetine, in combination with azoles against Candida albicans both in vitro and in vivo and explored the underlying mechanism. MICs, sessile MICs, and time-kill curves were determined for resistant C. albicans Galleria mellonella was used as a nonvertebrate model for determining (...) for the combination of fluconazole and fluoxetine. In addition, the time-kill curves confirmed the synergism dynamically. The results of the G. mellonella studies agreed with the in vitro analysis. In the mechanism study, we observed that fluconazole plus fluoxetine caused downregulation of the gene expression levels of SAP1 to SAP4 and weakened the extracellular phospholipase activities of resistant C. albicans The combinations of azoles and fluoxetine showed synergistic effects against resistant C. albicans may

2016 Antimicrobial Agents and Chemotherapy

195. N-Desmethylclozapine, Fluoxetine and Salmeterol inhibit post-entry stages of dengue virus life-cycle. Full Text available with Trip Pro

N-Desmethylclozapine, Fluoxetine and Salmeterol inhibit post-entry stages of dengue virus life-cycle. Around 10,000 people die each year due to severe dengue disease, and two-thirds of the world population lives in a region where dengue disease is endemic. There has been remarkable progress in dengue virus vaccine development; however, there are no licensed antivirals for dengue disease, and none appear to be in clinical trials. We took the approach of repositioning approved drugs for anti (...) -dengue virus activity by screening a library of pharmacologically active compounds. We identified N-desmethylclozapine, fluoxetine hydrochloride, and salmeterol xinafoate as dengue virus inhibitors based on reductions in the numbers of infected cells and viral titers. Dengue virus RNA levels were diminished in inhibitor-treated cells, and this effect was specific to dengue virus, as other flaviviruses, such as Japanese encephalitis virus and West Nile virus, or other RNA viruses, such as respiratory

2016 Antimicrobial Agents and Chemotherapy

196. Fluoxetine vs. placebo for the treatment of recurrent vasovagal syncope with anxiety sensitivity. (Abstract)

Fluoxetine vs. placebo for the treatment of recurrent vasovagal syncope with anxiety sensitivity. The optimal medical therapy of patients with vasovagal syncope (VVS) remains controversial. Fluoxetine is effective against anxiety and panic disorders, while its use has shown promising results for VVS. Anxiety sensitivity is a personality trait observed in a considerable proportion of patients with VVS, associated with predisposition to anxiety and panic disorders. Our aim was to examine whether (...) fluoxetine exerts beneficial effects regarding VVS prevention in the subset of patients with anxiety sensitivity.We assessed 106 patients with typical history of recurrent VVS, without other comorbidities, and a diagnostic, positive head-up tilt test. A psychiatric examination ruled out clinical psychiatric disease. Their psychological, stress-related profile was assessed by the Anxiety Sensitivity Index (ASI) questionnaire, a 16-item questionnaire, assessing fear of anxiety-related sensations

2016 Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Controlled trial quality: uncertain

197. Comparison of Saffron versus Fluoxetine in Treatment of Mild to Moderate Postpartum Depression: A Double-Blind, Randomized Clinical Trial. Full Text available with Trip Pro

Comparison of Saffron versus Fluoxetine in Treatment of Mild to Moderate Postpartum Depression: A Double-Blind, Randomized Clinical Trial. Introduction: Postpartum depression is a common mental health problem that is associated with maternal suffering. The aim of this double-blind clinical trial was to compare safety and efficacy of saffron and fluoxetine in treatment of mild to moderate postpartum depression. Methods: This was a 6-week, double-blind, randomized clinical trial. Subjects were (...) women aged 18-45 years with mild to moderate postpartum depression who had Hamilton Depression Rating Scale (HDRS 17-item) score≤18. Eligible participants were randomized to receive either a capsule of saffron (15 mg capsule) or fluoxetine (20 mg capsule) twice daily for 6 weeks. The primary outcome measure was to evaluate efficacy of saffron compared to fluoxetine in improving depressive symptoms (HDRS score). Results: There was no significant effect for time×treatment interaction on HDRS score [F

2016 Pharmacopsychiatry Controlled trial quality: predicted high

198. Compared with fluoxetine monotherapy, mirtazapine plus venlafaxine or fluoxetine increase remission but not response in patients with major depressive disorder

Compared with fluoxetine monotherapy, mirtazapine plus venlafaxine or fluoxetine increase remission but not response in patients with major depressive disorder Compared with fluoxetine monotherapy, mirtazapine plus venlafaxine or fluoxetine increase remission but not response in patients with major depressive disorder | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any (...) time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Compared with fluoxetine monotherapy, mirtazapine plus venlafaxine

2010 Evidence-Based Mental Health

199. Efficacy of combination of fluoxetine and cognitive behavioral therapy and fluoxetine alone for the treatment of obsessive compulsive disorder. (Abstract)

Efficacy of combination of fluoxetine and cognitive behavioral therapy and fluoxetine alone for the treatment of obsessive compulsive disorder. A number of pharmacological approaches as well as psychological interventions are effective in the treatment of obsessive-compulsive disorder (OCD). The present study was conducted to see the relative efficacy of treatment approaches. 30 diagnosed cases of OCD were taken and divided into two groups. Each group consisted of 15 patients. Group A (N=15 (...) ) received capsule fluoxetine and Group B (N=15) received capsule fluoxetine and CBT (13 weekly sessions). Twenty six participants completed the study (13 in each group). Dhaka University Obsessive-compulsive Scale (DUOCS) was used to measure the symptom severity. Symptom scores were measured at weeks 1, 5, 9 and 13. After 13 weeks, analysis of the data was done and the means of initial DUOCS score and 13th week score were compared. In both the groups the mean score changes were highly significant (p

2013 Pakistan journal of pharmaceutical sciences Controlled trial quality: uncertain

200. Continued Effectiveness of Relapse Prevention Cognitive-Behavioral Therapy Following Fluoxetine Treatment in Youth With Major Depressive Disorder. (Abstract)

Continued Effectiveness of Relapse Prevention Cognitive-Behavioral Therapy Following Fluoxetine Treatment in Youth With Major Depressive Disorder. To evaluate the continued effect of a sequential treatment strategy (fluoxetine followed by continued medication plus relapse prevention cognitive-behavioral therapy [RP-CBT]) on relapse prevention beyond the treatment phase.Youth (aged 8-17 years) with major depressive disorder (MDD) were treated with fluoxetine for 6 weeks. Responders (≥50

2015 Journal of the American Academy of Child and Adolescent Psychiatry Controlled trial quality: uncertain

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