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101. Diabetes - type 2

, planning a pregnancy, or breastfeeding. It also does not cover the diagnosis and management of impaired glucose regulation, or make detailed recommendations on the diagnosis and management of other types of diabetes. There are separate CKS topics on and . The target audience for this CKS topic is healthcare professionals working within the NHS in the UK, and providing first contact or primary healthcare. How up-to-date is this topic? How up-to-date is this topic? Changes Changes September 2019 — minor (...) on fitness to drive from the DVLA's At a glance guide to the current medical standards of fitness to drive . A tabulated version of the treatment recommendations for blood glucose control, to aid navigation. August 2011 — minor update. There is a small increased risk of bladder cancer associated with pioglitazone use. This information is based on advice from the MHRA and the EMA. Issued in September 2011. July 2011 — minor update. Cough is included as a very rare but possible adverse effect

2019 NICE Clinical Knowledge Summaries

102. Chronic obstructive pulmonary disease

be discussed when appropriate and advance care planning offered. Have I got the right topic? Have I got the right topic? From age 35 years onwards. This CKS topic covers the diagnosis, management, and referral of people with chronic obstructive pulmonary disease (COPD). There are separate CKS topics on , , , , , , , , and . The target audience for this CKS topic is healthcare professionals working within the NHS in the UK, and providing first contact or primary healthcare. How up-to-date is this topic? How (...) of the multidisciplinary team are based on the National Institute for Health and Care Excellence (NICE) guideline Management of chronic obstructive pulmonary disease in adults in primary and secondary care (partial update) [ ; ]. Treatment What treatment should I offer a person with COPD? Inhaled treatments (FEV1 50% predicted or greater) Inhaled treatments (FEV1 50% predicted or greater) Inhaled bronchodilators are the first-line drugs for the treatment of chronic obstructive pulmonary disease (COPD). They reduce

2019 NICE Clinical Knowledge Summaries

103. Cancer Genetics Risk Assessment and Counseling (PDQ®): Health Professional Version

the scope and goals of genetic counseling. Am J Med Genet C Semin Med Genet 142C (4): 269-75, 2006. [ ] Baty BJ, Kinney AY, Ellis SM: Developing culturally sensitive cancer genetics communication aids for African Americans. Am J Med Genet 118A (2): 146-55, 2003. [ ] Jenkins JF, Lea DH: Nursing Care in the Genomic Era: A Case-Based Approach. Sudbury, Mass: Jones and Bartlett Publishers, 2005. Meiser B, Gaff C, Julian-Reynier C, et al.: International perspectives on genetic counseling and testing (...) , surgeries, biopsies, major illnesses, medications, and reproductive history (for women, this includes age at menarche, parity, age at first live birth, age at menopause, and history of exogenous hormone use). Screening practices and date of last screening exams, including imaging and/or physical examinations. Environmental exposures. Past and current alcohol intake and tobacco use. Diet, exercise, and complementary and alternative medicine practices may also be assessed. For consultands with a history

2018 PDQ - NCI's Comprehensive Cancer Database

104. The cost of the school holidays

provision ? Address barriers to participation caused by the requirement for block-booking, advance payment and face-to-face booking ? Ensure holiday provision is promoted far in advance to support family planning and budgeting for holiday activities ? Address the issue of transport costs to access holiday provision through the provision of holiday travel passes. Adapting content and delivery ? Ensure co-design of services with local people ? Ensure support for parents over holiday periods via provision (...) parents with differing levels of engagement with Glasgow Life holiday provision. ? 2 focus groups were held without any specific demographic in mind: the first with parents of children attending a breastfeeding support group and toddler tales session and another with parents attending a regular support group ? 2 focus groups were held with lone parents due to their prevalence in the city - 40% of families with children in Glasgow are lone parent families – and the greater likelihood of these families

2015 Glasgow Centre for Population Health

105. Infertility

the initial assessment and management of a couple who is concerned about infertility. This CKS topic does not cover secondary and tertiary care management of infertility, but briefly outlines the treatments that are offered. It also does not cover the treatment of impotence, or issues around surrogacy or sperm and egg banking. There are separate CKS topics on , , , , , and . The target audience for this CKS topic is healthcare professionals working within the NHS in the UK, and providing first contact (...) people have been trying to conceive without success after which formal investigation is justified and possible treatment implemented [ ]. Infertility has been defined as failure to conceive after frequent unprotected sexual intercourse for one or two years. However, NICE highlights that the diagnosis of infertility based on a failure to conceive within 1 year may exaggerate the risk of infertility, since up to half of women who do not conceive in the first year are likely to do so in the second year

2018 NICE Clinical Knowledge Summaries

106. Evidence-Based Policy Making: Assessment of the American Heart Association?s Strategic Policy Portfolio Full Text available with Trip Pro

the evidence behind AHA’s policies to determine how well they address the association’s 2020 cardiovascular health (CVH) metrics and cardiovascular disease (CVD) management indicators and identified research needed to fill gaps in policy and support further policy development. Methods and Results— The AHA policy research department first identified current AHA policies specific to each CVH metric and CVD management indicator and the evidence underlying each policy. Writing group members then reviewed each (...) effectiveness. Provide FDA Regulation of Tobacco AHA worked with Congress to pass the 2009 Family Smoking and Tobacco Control Act. This legislation, for the first time, gave the FDA the oversight authority to regulate tobacco products and to restrict tobacco company efforts to addict more children and adults. The AHA continues to work with the FDA and the Center for Tobacco Products to provide evidence and advice with potential to facilitate the development and implementation of FDA regulatory and other

2016 American Heart Association

107. Assessing Fitness to Drive

responsibility for any consequences arising from the use of information herein. Readers should rely on their own skill and judgement to apply information to particular issues. Document History 1 September 2016 Document first published. 1 August 2017 Corrections relating to repaired abdominal and thoracic aneurysms to reflect agreed policy (page 51) and visual aids (page 127). Contact details updated in Appendix 9.Assessing Fitness to Drive for commercial and private vehicle drivers 2016 Medical standards (...) licensing authority (see Appendix 9 for details). Information is also available from the Austroads website: Assessing Fitness to Drive First Published 1998 Second Edition 2001 Third Edition 2003 Reprinted 2006 Fourth Edition 2012 Reprinted 2013 Fifth Edition 2016 Reprinted 2017 © Austroads Ltd 2017 This work is copyright. Apart from any use as permitted under the Copyright Act 1968, no part may be reproduced by any process without the prior written permission of Austroads. National

2016 Cardiac Society of Australia and New Zealand

108. WHO guidelines for the treatment of Treponema pallidum (syphilis)

) Methodologist: Nancy Santesso. ACKNOWLEDGEMENTSWHO GUIDELINES FOR THE TREATMENT OF TREPONEMA PALLIDUM (SYPHILIS) iv ABBREVIATIONS AND ACRONYMS AIDS acquired immune deficiency syndrome AMR antimicrobial resistance CI confidence interval DFA direct fluorescent antibody DNA deoxyribonucleic acid DOI declaration of interests FTA-ABS fluorescent treponemal antibody absorbed GDG Guideline Development Group GRADE Grading of Recommendations Assessment, Development and Evaluation GUD genital ulcer disease HIV human (...) – to end the epidemics of AIDS and other communicable diseases; target 3.4 – to reduce premature mortality from noncommunicable diseases and promote mental health and well-being; target 3.7 – to ensure universal access to sexual and reproductive health-care services; and target 3.8 – to achieve universal health coverage. Worldwide, more than a million curable STIs are acquired every day. In 2012, there were an estimated 357 million new cases of curable STIs among adults aged 15–49 years worldwide: 131

2016 World Health Organisation Guidelines

109. What is the evidence on the reduction of inequalities in accessibility and quality of maternal health care delivery for migrants? A review of the existing evidence in the WHO European Region

. Culturally sensitive provision of language support and good educational aids will tackle some of these barriers. Affordability This is a major barrier to accessing care. Failure to access care prenatally often leads to more expensive emergency care as well as to unwanted pregnancy outcomes, and strategies such as promoting and investing in family planning can be a cost–effective way to improve migrant women’s health and prevent unintended pregnancies. Quality of care Universal definitions of indicators (...) are women (world average is 48%) (15). Recent data show that women also represent a growing proportion of migrant workers who travel to Kazakhstan and the Russian Federation, primarily from other countries of the Commonwealth of Independent States (CIS) (15–17). Consequently, maternal health care is a significant issue in provision of health care to migrants of all types.3 In 2010, WHO stated that reproductive health included “the right of access to appropriate health care services that will enable

2016 WHO Health Evidence Network

110. WHO recommendations on antenatal care for a positive pregnancy experience

women after the first trimester as part of worm infection reduction programmes. x Context-specific recommendation T etanus toxoid vaccination C.5: T etanus toxoid vaccination is recommended for all pregnant women, depending on previous tetanus vaccination exposure, to prevent neonatal mortality from tetanus. y Recommended Recommendations integrated from other WHO guidelines that are relevant to ANC Malaria prevention: intermittent preventive treatment in pregnancy (IPT p) C.6: In malaria-endemic

2016 World Health Organisation Guidelines

111. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection

infection, WHO, for the first time, recommends that all people living with HIV be provided with antiretroviral therapy (ART). This will bring us one step closer to achieving universal access to HIV treatment and care and ending AIDS as a public health threat. These guidelines also make service delivery recommendations on how we can expand coverage of HIV treatment to reach the 37 million people living with HIV. Key recommendations aim to improve the quality of HIV treatment and bring us closer (...) Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection For more information, contact: World Health Organization Department of HIV/AIDS 20, avenue Appia 1211 Geneva 27 Switzerland E-mail: ISBN 978 92 4 154968 4 GUIDELINES CONSOLIDATED GUIDELINES ON THE USE OF ANTIRETROVIRAL DRUGS FOR TREATING AND PREVENTING HIV INFECTION 2016 RECOMMENDATIONS FOR A PUBLIC HEALTH APPROACH SECOND EDITION CONSOLIDATED GUIDELINES

2016 World Health Organisation HIV Guidelines

112. Point-of-care calprotectin tests

specialist nurses, and therefore can still be resource demanding, so the effect on referral behaviour is difficult to predict (4). The rapid test kits could enable the use of calprotectin as a first line diagnostic aid in determining the presence or absence of gastrointestinal pathology, in combination with traditional methods. Patients presenting to primary care with non-acute intestinal symptoms and no “red flag” features would potentially be suitable candidates for faecal calprotectin testing. As some (...) calprotectin tests; Quantum Blue®, PreventID by CalDetect® and Calpro® all of which are based on a chromatographic immunoassay technique. The faecal sample is prepared for testing by first dissolving into solution. This involves inserting a smear sample of stool into an extraction device which is a prepared tube/pipette containing buffer solution, and mixing. The test kit itself is a plastic cassette or lateral flow device, with a window displaying a test line and control line. The test line contains anti

2014 Publication 4878904

113. Farmer Field Schools for Improving Farming Practices and Farmer Outcomes: A Systematic Review Full Text available with Trip Pro

: Corresponding Author E-mail address: International Initiative for Impact Evaluation (3ie) London International Development Centre London WC1H 0PD Email: Email: First published: 01 September 2014 Citations: Contributions The review was undertaken by Jorge Hombrados (JH), Daniel Phillips (DP), Birte Snilstveit (BS), Martina Vojtkova (MV) and Hugh Waddington (HJW). HJW and BS developed the study protocol. HJW led the quantitative effectiveness synthesis and compiled the overall systematic review report. BS led (...) and 70s during the “Green Revolution” improved agricultural yields substantially in those areas it reached and raised national production and food security ( ). However, a number of challenges emerged. The first problem was that poor farmers were being left behind, particularly in Sub‐Saharan Africa where many were not reached by modernisation approaches. Those technologies that were promoted were not appropriate to the challenges facing smallholders in the African context, particularly women farmers

2014 Campbell Collaboration

114. WHO recommendations on health promotion interventions for maternal and newborn health 2015

promotion approach set out in the Ottawa Charter into national maternal and newborn health strategies. More than 10 years after the original framework was published, it is time to update the evidence for the key interventions and for community participation, using the methods set out by the WHO Guideline Review Committee. In June 2012 a steering group met for the first time to discuss the IFC Framework, propose priority research questions, define priority outcomes, and discuss methods for searching (...) , retrieving, and synthesizing the evidence likely to be available for the research questions. This guideline was developed in accordance with the procedures outlined in the WHO Handbook for guideline development, 2 including a Technical Consultation held with a Guideline Development Group (GDG), made up of an international group of experts. The first meeting of the GDG was held in July 2013 at the WHO headquarters in Geneva, Switzerland. At that time the priority research questions were reviewed, key

2015 World Health Organisation Guidelines

115. Recommendation on 36 months isoniazid preventive therapy to adults and adolescents living with HIV in resource-constrained and high TB and HIV-prevalence settings: 2015 update

received non-monetary support from Qiagen (formerly Cellestis) and Oxford Immunotech to perform investigator-initiated research studies, where the kits were in part provided free-of-charge by the two companies. She received travel support from Qiagen for presentation of the data in scientific meetings. She is a co-inventor for a patent application entitled “in vitro process for the quick determination of a patient’s status relating to infection with Mycobacterium tuberculosis” (international patent (...) and writing of the guidelines Alberto Matteelli with input from Haileyesus Getahun. WHO Steering Group Dennis Falzon (Global TB Programme, WHO), Nathan Ford (HIV/AIDS Department, WHO), Haileyesus Getahun (Global TB Programme, WHO), Chris Gilpin (Global TB Programme, WHO), Christian Lienhardt (Global TB Programme, WHO), Knut Lönroth (Global TB Programme, WHO), Alberto Matteelli (Global TB Programme, WHO), Lisa Nelson (HIV/AIDS Department, WHO), Andreas Reis (Knowledge, Ethics and Research Department, WHO

2015 World Health Organisation Guidelines

116. Chronic Pelvic Pain

with these patients. We therefore plan to make a stepped information structure, in alignment with stepped care protocols. It is the vision of the panel to use new digital information sources like websites and apps to aid this process. Furthermore, the panel wishes to change the guideline according to the template used in all other non-oncology guidelines of the EAU. It has been recognised that structuring a guideline on chronic pain is quite different from structuring one on another subject. Multidisciplinarity (...) is of utmost importance and demands a broad view. For the 2016 version the panel has made plans focussing on two important changes to the guideline. The first one is to rewrite the guideline in such a way that it is centred around pain instead of being organ centred. Chapters are now named after the organ or after the specialist that is consulted by the patient. For the 2016 edition of this guideline, pain will be the centre and every other information will be build around this central theme. The guideline

2015 European Association of Urology

117. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer

to stratify the risk of malignancy in thyroid nodules, and aid decision-making about whether FNA is indicated. Studies consistently report that several US gray scale features in multivariate analyses are associated with thyroid cancer, the majority of which are PTC. These include the presence of microcalci?cations, nodule hypoechogenicity compared with the surrounding thyroid or strap muscles, irregular margins (de?ned as either in?ltrative, microlobulated, or spiculated), and a shape taller than wide

2015 Pediatric Endocrine Society

118. Community management of opioid overdose

and Clinical Toxicologists), Marica Ferri (European Monitoring Centre for Drugs and Drug Addiction), Mauro Guarinieri (the Global Fund to Fight AIDS, Tuberculosis and Malaria), Sharon Stancliff (Harm Reduction Association, USA), Marc Augsburger (The International Association of Forensic Toxicologists), Ruth Birgin (International Network of People who Use Drugs), Hannu Alho (International Society of Addiction Medicine), Simon Lenton (National Drug Research Institute, Australia), Steven Gust (National (...) reviews, presented the findings to the GDG, wrote the first draft of the guidance and assisted with preparation of the final guideline document. Anna Williams and Rebecca McDonald assisted with the preparation of background documentation. WHO staff: Tomas Allen (WHO library) assisted with the development and conduct of the literature search. WHO interns: Agata Boldys (Management of Substance Abuse unit) assisted with the organization of the meeting and the preparation of background documents. Sally

2015 World Health Organisation Guidelines

119. UK National Guideline for the Management of Anogenital Herpes

Objectives The overall aim of the guideline is to prevent morbidity (physical and psychological) associated with genital herpes and ultimately to reduce transmission and prevalence. For some groups, particularly those at high risk of HIV this may have the added benefit of limiting HIV cases. The guideline provides recommendations on the management of adults with anogenital herpes in the UK. Recommendations include diagnostic tests, management of the primary or first episode of anogenital herpes (...) in a representative clinic. The process was overseen by the Clinical Effectiveness Group of BASHH. This is the third revision of the UK national guideline first written in 1999. Definitions Initial episode: First episode with either herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). Dependent on whether the individual has had prior exposure to the other type, this is further subdivided into: Primary infection: first infection with either HSV-1 or HSV-2 in an individual with no pre-existing antibodies

2015 British Association for Sexual Health and HIV

120. Guidelines on the management of latent tuberculosis infection

of TB related to treatment with bio similar TNF antagonists for one time in 2013. Martina Sester declared that she received non-monetary support from Qiagen and Oxford Immunotech to perform investigator-initiated research studies, where the kits were in part provided free-of-charge by the two companies. She received travel support from Qiagen for presentation of the data in scientific meetings. She is a co-inventor for a patent application entitled “in vitro process for the quick determination (...) Acknowledgements Overall coordination and writing of the guidelines Haileyesus Getahun and Alberto Matteelli helped coordinate the development and drafting of the guidelines, under the overall direction of Mario Raviglione. WHO Steering Group Dennis Falzon (Global TB Programme, WHO), Nathan Ford (HIV/AIDS Department, WHO), Haileyesus Getahun (Global TB Programme, WHO), Chris Gilpin (Global TB Programme, WHO), Christian Lienhardt (Global TB Programme, WHO), Knut Lonnroth (Global TB Programme, WHO), Alberto

2015 World Health Organisation Guidelines

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