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Fetal Heart Tracing

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221. HTA of smoking cessation interventions

for the National Clinical Programme for Acute Coronary Syndrome, HSE Dr Paul Kavanagh Specialist in Public Health Medicine, HSE Dr Marcus Kennedy Interventional Pulmonologist, Consultant Respiratory and General Physician, Cork University Hospital Prof Deirdre Madden Professor, Faculty of Law, University College Cork Ms Patricia McQuillan Practice Nurse Development Co-ordinator, Asthma and COPD Clinical Programme, HSE Dr Patrick Moran Senior HTA Analyst, HIQA (Project Lead) Health Technology Assessment (HTA (...) . Smoking during pregnancy is harmful. It is associated with an increased risk of congenital anomalies, preterm birth, intrauterine fetal growth restriction, placental abruption, stillbirth, sudden infant death syndrome, respiratory infection, adverse cognitive and behavioural outcomes in infancy, and the development of chronic disease in adulthood. Evidence shows that smokers with mental health disorders smoke more heavily, are more nicotine dependent, and have smoked for longer than smokers who do

2017 Health Information and Quality Authority

222. Analgesia and Anesthesia for the Breastfeeding Mother

. Of the anticholinergic agents, atropine is found in trace amountsinbreastmilk.Glycopyrrolateisnotexpected tobefoundinbreastmilkandispoorlyabsorbedthrough the gastrointestinal tract. 5 Antiemetics are used commonly in the perioperative period, and most of these medications are considered safe during breastfeeding. Ondansetron, dexamethasone, and metoclopramide may be preferred because of their lack of sedating side effects. 3 (IV) Prochlorperazine, promethazine, and scopolamine are likely safe, but may lead (...) 4 hours around the clocksincehercesareandelivery6daysbefore. 38 (III) Remifentanil. Although there are no published data on remifentanil, this esterase-metabolized opioid has abriefhalf-lifeevenininfants(<10minutes)andhas been documented to produce no fetal sedation even in utero. Although its duration of action is limited, it could be used safely and indeed may be ideal in breastfeeding mothers for short painful procedures. Sufentanil. Sufentanil transfer into milk has not been published

2017 Academy of Breastfeeding Medicine

224. Hepatitis C in pregnancy: screening, treatment, and management Full Text available with Trip Pro

categories: velpatasvir, dacla- tasvir, ombitasvir/paritaprevir/ritonavir/dasabuvir, ledipasvir, and elbasvir/grazoprevir. Again, the limited animal data that exist have not shown a risk to the fetus. 47-51 Another DAA therapy without an assigned FDA pregnancy category is simeprevir, which has shown fetal toxicity in animal studies. 52 Due to the lack of human studies, no DAA therapy has yet been approved to treat HCV infection in pregnancy. 1 Given the availability of ribavirin-free DAA regimens (...) compared with no internal monitoring. In contrast, a retrospective study with 724 women found no association. 60 One of these studies alsofoundthatepisiotomywassigni?cantlyassociatedwith an increased risk of vertical transmission. 59 Based on the availableevidence,werecommendthatobstetriccareproviders avoid internal fetal monitoring, prolonged rupture of membranes, andepisiotomyinmanaginglaborinHCV-positivewomen(GRADE 1B), unless it is unavoidable in the course of management (ie, when unable to trace

2017 Society for Maternal-Fetal Medicine

225. Management of bleeding in the late preterm period

abruption is defined as placental separation, either partial or complete, prior to delivery. Classically, women with placental abruption present with abdominal pain and bleeding, and approximately 60% will also have a nonreassuring fetal heart rate tracing. x 32 Hurd, W.W., Miodovnik, M., Hertzberg, V., and Lavin, J.P. Selective management of abruptio placentae: A prospective study. Obstet Gynecol . 1983 ; 61 : 467–473 | | | Numerous risk factors for placental abruption have been described (...) : 911–915 | | | | | If the diagnosis is unclear, bleeding is minimal, and the maternal and fetal status remain stable, delivery may be delayed with close surveillance and ongoing fetal testing. However, as with other women presenting with active hemorrhage from any etiology in the late preterm period, delivery is indicated in the setting of abruption with significant vaginal bleeding, abnormal laboratory results including acute anemia or coagulopathy, abnormality of the fetal heart tracing

2017 Society for Maternal-Fetal Medicine

226. First Trimester Vaginal Bleeding

) of the pregnancy should generally be avoided in the first trimester due to concerns about potential bioeffects in the developing embryo [57-59]. Documentation of embryonic cardiac activity is best done with M- mode US as the heart rate can be measured. Video clips can also be used to document embryonic cardiac activity. Once a normal IUP has been excluded, Doppler US may be useful when other diagnoses such as RPOC are suspected. Doppler US is not generally needed to make a diagnosis of GTD, but may be helpful (...) heart rate by 8 weeks at US. Radiology. 2005;236(2):643-646. 25. Bromley B, Harlow BL, Laboda LA, Benacerraf BR. Small sac size in the first trimester: a predictor of poor fetal outcome. Radiology. 1991;178(2):375-377. ACR Appropriateness Criteria ® 9 First Trimester Vaginal Bleeding 26. Horrow MM. Enlarged amniotic cavity: a new sonographic sign of early embryonic death. AJR Am J Roentgenol. 1992;158(2):359-362. 27. McKenna KM, Feldstein VA, Goldstein RB, Filly RA. The empty amnion: a sign of early

2017 American College of Radiology

227. Interventions Targeting Sensory Challenges in Children with Autism Spectrum Disorder - An Update

and Developmental Delay. J Can Acad Child Adolesc Psychiatry. 2011 Aug;20(3):214-6. PMID: 21804851.X-1 745. Mason MC. Head for bed. Nurs Stand. 2011 Jan 26-Feb 1;25(21):20. PMID: 21329128.X-1 746. Mathewson KJ, Drmic IE, Jetha MK, et al. Behavioral and cardiac responses to emotional stroop in adults with autism spectrum disorders: influence of medication. Autism Res. 2011 Apr;4(2):98-108. doi: 10.1002/aur.176. PMID: 21360828.X-1 747. Matisz CE, McDougall JJ, Sharkey KA, et al. Helminth parasites

2017 Effective Health Care Program (AHRQ)

228. SURGICAL TREATMENT OF LUMBAR DISC HERNIATION IN PREGNANT WOMEN: REPORT OF TWO CASES AND A SYSTEMATIC REVIEW Full Text available with Trip Pro

components of intraoperative management of pregnant patients is monitoring of the cardiac fetal activity. According to some authors, intraoperative monitoring of fetal heartbeat at a gestational age of up to 20 weeks is not indicated; starting with the 23rd week, this procedure is mandatory; monitoring between 20 and 23 weeks is controversial. Given the influence of general anesthesia on fetal heart activity, as well as inadequate development of the fetal cardiovascular system, the data obtained at up (...) to the postoperative ultrasound, there were no fetal abnormalities. But later, it turned out that the pregnant patient was carrying twins, and a spontaneous miscarriage of one fetus occurred. The second fetus developed normally, and the patient gave birth to a healthy child at 39 weeks. In this case, it is difficult to establish the degree of influence of the surgery on the course of the pregnancy because according to the ultrasound, the pregnancy was preserved immediately after surgery. In pregnant females

2018 Coluna/Columna

230. Polyhydramnios in singleton pregnancies

factors for arrest of descent during the second stage of labor. Int J Gynaecol Obstet 2002; 77(1):7-14. 102. Sheiner E, Levy A, Feinstein U, Hershkovitz R, Hallak M, Mazor M. Obstetric risk factors for failure to progress in the first versus the second stage of labor. J Matern Fetal Neonatal Med 2002; 11(6):409-413. 103. Hadar A, Sheiner E, Hallak M, Katz M, Mazor M, Shoham-Vardi I. Abnormal fetal heart rate tracing patterns during the first stage of labor: effect on perinatal outcome. Am J Obstet (...) to search for evidence of a pathological condition in the fetus or pregnant woman. A control program is then initiated to see if the amnion volume increases, if the fetus is affected or if the pregnant woman gets symptoms. To avoid pregnancy and birth related complications such as preterm birth, PPROM, placental abruption, fetal distress, cord prolapse, dystocia, and postpartum hemorrhage, it is important to have a plan to control the pregnant woman with polyhydramnios during pregnancy and delivery

2016 Nordic Federation of Societies of Obstetrics and Gynecology

231. Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critically Ill Patient

no recommendations for nine of the topics. 1) We make no recommendation as to whether neuromuscular blockade is beneficial or harmful when used in patients with acute brain injury and raised intracranial pressure. 2) We make no recommendation on the routine use of neuromuscular-blocking agents for patients undergoing therapeutic hypothermia following cardiac arrest. 3) We make no recommendation on the use of peripheral nerve stimulation to monitor degree of block in patients undergoing therapeutic hypothermia (...) ; please refer to any of the basic anesthesiology textbooks for a description of neuromuscular blockade reversal. | Effects of NMBAs Outside the Neuromuscular Junction Most of the effects of NMBAs that occur outside the neuromuscular junction are cardiac in nature and are due to histamine release and ganglionic or muscarinic stimulation manifested by vagolytic actions, ganglionic blockade, or sympathetic stimulation. Although pancuronium and atracurium have the greatest potential to cause adverse

2016 Society of Critical Care Medicine

232. Practice Guidelines for Obstetric Anesthesia Full Text available with Trip Pro

information or cautionary notes based on this information. Guidelines Perianesthetic Evaluation and Preparation Perianesthetic evaluation and preparation topics include (1) a focused history and a physical examination, (2) an intrapartum platelet count, (3) a blood type and screen, and (4) perianesthetic recording of fetal heart rate patterns. History and Physical Examination. Literature Findings: Although it is a well-accepted clinical practice to review medical records and conduct a physical examination (...) policies. Perianesthetic Recording of Fetal Heart Rate Patterns. Literature findings: Studies with observational findings and case reports indicate that fetal heart rate patterns may change after the administration of neuraxial anesthetics ( Category B3/B4 evidence ). Survey Findings: The consultants and ASA members strongly agree that fetal heart rate patterns should be monitored by a qualified individual before and after administration of neuraxial analgesia for labor. Recommendations

2016 American Society of Anesthesiologists

233. Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment

are agreeing to our use of cookies. Free Access article Share on Jump to Free Access article Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment A Scientific Statement From the American Heart Association , PhD, FAHA, Chair , PhD, FAHA , MD, FAHA , PhD , PhD, RD, FAHA , PhD , ScD, ACE, FAHA , and MD, FAHA PhD, Co-Chairon behalf of the American Heart Association Council on Functional Genomics and Translational Biology (...) , Council on Epidemiology and Prevention, and Stroke Council Jane F. Ferguson , Hooman Allayee , Robert E. Gerszten , Folami Ideraabdullah , Penny M. Kris-Etherton , José M. Ordovás , Eric B. Rimm , Thomas J. Wang , and Brian J. Bennett and on behalf of the American Heart Association Council on Functional Genomics and Translational Biology, Council on Epidemiology and Prevention, and Stroke Council Originally published 19 Apr 2016 Circulation: Cardiovascular Genetics. 2016;9:291–313 You are viewing

2016 American Heart Association

234. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection

infected and reducing the number of people dying from HIV-related causes over the coming years. The number of people eligible for ART increases from 28 million to all 37 million people currently living with HIV globally. iv Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection Expanding access to treatment is at the heart of a new treatment targets for 2020 with the aim of ending the AIDS epidemic as a public health threat by 2030. The 90–90–90 targets

2016 World Health Organisation HIV Guidelines

235. Understanding the Public Health Implications Concerning Shale Gas Production and Hydraulic Fracturing

, inadequate storage or disposal of wastewater, and truck transport of fluids to and from the pad. Flowback and produced water from the hydraulic fracturing process especially can be a source of water contamination since these contain fracturing chemicals as well as compounds from the shale reservoir, including salts, natural occurring radioactive material such as radon gas, trace metals (e.g., arsenic), and natural gas (predominantly methane). Episodes of contamination from large spills linked to shale (...) linkage study related birth outcomes to maternal residential proximity to natural gas production sites in Colorado. Within a 10-mile radius of natural gas wells and with greater gas well density there were statistically significant positive associations with congenital heart defects, but not of oral clefts, nor were there positive associations with preterm birth or term low birth weight. 85 Exposure to benzene and volatile aromatic hydrocarbons were suggested to be causal factors; however

2016 National Collaborating Centre for Environmental Health

236. Sivextro - tedizolid phosphate

Investigation Plan PK pharmacokinetics Assessment report EMA/83337/2015 Page 7/110 Abbreviation Definition popPK population pharmacokinetics PSE pseudoephedrine PSM phenol-soluble modulins PT Preferred Term PVC PVdC PTE polyvinyl chloride polyvinylidene chloride post therapy evaluation PVL Panton-Valentine leukocidin toxin QTc QT interval corrected for heart rate QTcF QT interval corrected for heart rate using Fridericia’s formula QTPP RBC Quality Target Product Profile red blood cell RH SA Relative

2015 European Medicines Agency - EPARs

238. Lumark - lutetium, isotope of mass 177

mammals and using different administration routes. Intraperitoneal administration resulted in generalized peritonitis with adhesion and accumulation of some ascetic fluid. By intraperitoneal route, the LD50 is approximately 300 mg/kg in mice and rats. By intravenous route, the LD50 in rats and mice ranges between 30 and 60 mg/kg. Intravenously administrated doses resulted in varying effects on the blood pressure and a decreased heart rate. Electrocardiograms showed no irregularities in cardiac rhythm (...) on the pharmacology, pharmacokinetics and toxicity of lutetium, which is acceptable under the proposed legal basis. A number of pharmacology studies from the literature have been presented that demonstrate a limited pharmacological effect of lutetium trichloride. Studies include a number of ex vivo studies with isolated organs – rabbit ileum and rabbit heart, in vivo study in cats, and a number of in vitro studies. The inorganic nature in general and the trivalent nature of the lutetium ion in particular governed

2015 European Medicines Agency - EPARs

239. Kolbam - cholic acid

suggesting both a vagally mediated and a direct effect on heart rate. The response was further diminished by ganglion blockade or decerebration (Joubert 1978). In feline isolated right ventricular papillary muscles low concentrations (3x10-9-3x10-7M) of CA induced a mild positive inotropic effect as well as an endocardial endothelium- dependent and ß-receptor mediated positive inotropic response. Higher concentrations of CA (>3x10- 7M ) or prolonged exposure to a single low concentration (3x10-8M) caused (...) extensive morphological damage to the endothelium (Colpaert et al. 1992). Two separate studies examined the influence of bile acids, including CA, on the actions of isoprenaline, adrenaline, noradrenaline and acetylcholine on the rat autonomic system on the heart in vivo and in vitro, using an isolated blood vessel preparation (Kadlubowski et al. 1984) and isolated rat intestine (Szkudlinski, 1984). Kadlubowski et al. reported that bile acids reduced the stimulating effect of isoprenaline, adrenaline

2015 European Medicines Agency - EPARs

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