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Fetal Heart Tracing

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181. Risk factors for breast cancer: A review of the evidence 2018

133 4.8.2 Cardiac glycosides 134 4.8.3 HPV 136 4.8.4 Hysterectomy 137 4.8.5 Pregnancy termination 139 4.8.6 Previous cancer other than breast cancer 140 4.8.7 Silicone breast implants 143 4.8.8 Stress 145 4.8.9 Trauma to the breast 147 4.8.10 Type 2 diabetes 148 4.9 Chemical exposures 150 4.9.1 Bisphenol A (BPA) 150 4.9.2 DDT exposure 151 4.9.3 Deodorant/antiperspirant 152 4.9.4 Dioxin 153 4.9.5 Ethylene oxide 155 4.9.6 Land contamination 156 4.9.7 Outdoor air pollution 158 4.9.8 Parabens 160 (...) and risk of breast cancer 393 Table D.53 Diet—processed meat and risk of breast cancer 395 Table D.54 Diet—red meat and risk of breast cancer 398 Table D.55 Environmental tobacco smoke and risk of breast cancer 401 Table D.56 Tobacco smoking and risk of breast cancer 405 Table D.57 Physical activity and risk of breast cancer 409 Table D.58 Shift work disrupting circadian rhythm and risk of breast cancer 415 Table D.59 Aspirin and risk of breast cancer 420 Table D.60 Cardiac glycosides and risk

2018 Cancer Australia

182. Syphilis in pregnancy

, transient accentuation of cutaneous lesions 47 , hypotension and tachycardia 38,40 · May precipitate uterine contractions (56–67%), decreased fetal movements (67%) and abnormal fetal heart rate (FHR) tracings (50%) 24 · In severely affected pregnancies preterm birth and stillbirth have been reported 24 Management · Do not delay treatment due to concerns about adequacy of monitoring · Offer information to women about JHR o Refer to Queensland Clinical Guideline Parent information · Advise women to: o (...) Abbreviations CSF Cerebrospinal fluid FHR Fetal heart rate GP General Practitioner HIV Human immunodeficiency virus IgM Immunoglobulin M IV Intravenous JHR Jarisch Herxheimer Reaction PCR Polymerase Chain Reaction POC Point of care QSSS Queensland Syphilis Surveillance Service SOP Standard operating procedure STI Sexually transmitted infection USS Ultrasound VDRL Venereal Diseases Research Laboratory Definition of terms Adequate treatment In a pregnant woman, treatment may be considered adequate if a stage

2020 Queensland Health

183. Protective measures for groups vulnerable to COVID-19

five years) ? having chemotherapy or radiotherapy. Chronic conditions that indicate moderate risk include: ? chronic kidney (renal) failure ? heart disease (coronary heart disease or failure) ? chronic lung disease, excluding mild or moderate asthma ? a non-haematological cancer (diagnosed in the last 12 months) ? diabetes ? severe obesity with a body mass index of 40 kg/m 2 or more ? chronic liver disease ? some neurological conditions such as stroke or dementia ? some chronic inflammatory (...) or interstitial lung disease and severe COPD ? People with rare diseases and inborn errors of metabolism that significantly increase the risk of infections (such as SCID, homozygous sickle cell) ? People on immunosuppression therapies sufficient to significantly increase risk of infection ? Women who are pregnant with significant heart disease, congenital or acquired. On 4 September, the Department of Health updated their criteria for extremely medically vulnerable to include people who are on dialysis. (2

2020 Health Information and Quality Authority

184. Canadian guidelines for controlled pediatric donation after circulatory determination of death-summary report Full Text available with Trip Pro

in these cases. Regarding GPS 36, in the past, when DCD was more commonly referred to as “donation after cardiac death,” authors argued that determining death by irreversible loss of cardiac function precluded DCD cardiac transplantation ( , ). However, our guidelines specifically define death as permanent loss of circulation in the donor. Whether the heart remains unresuscitated in the donor or is removed and resuscitated in another patient does not alter donor outcome: body and brain circulation remains (...) in cardiac pDCD: a) Cardiac transplant programs should establish criteria for acceptance of heart donation, ex vivo cardiac protocols, and heart allocation in pDCD, b) Consideration should be given to initiate cardiac pDCD program as either research protocols with research ethics board oversight or through programs that oversee innovative therapies. | Justification. Although there is minimal published experience with cardiac pDCD ( ), recent innovative reports of adult cardiac DCD using ex vivo heart

2017 CPG Infobase

185. Canadian immunization guide chapter on influenza and statement on seasonal influenza vaccine for 2017-2018

(traces) Gentamicin None Kanamycin Neomycin Kanamyci n Neomycin Neomycin None No Gentamicin None None Other clinically relevant non- medicinal ingredients* Egg protein, Chicken protein, Formalde- hyde, CTAB, Polysorbate 80 Egg protein, a-tocopheryl hydrogen succinate, Polysorbate 80, Formalde- hyde, Ethanol, Sodium deoxycholate, Sucrose Egg protein, Formalde- hyde, Polysorbate 80, CTAB Egg protein, Formalde- hyde,Poly- sorbate 80, CTAB Egg protein, Formalde- hyde, Triton X- 100 Egg protein, Formalde (...) ) France EK, McClure D, Hambidge S, et al. Impact of maternal influenza vaccination during pregnancy on the incidence of acute respiratory illness visits among infants. Arch Pediatr Adolesc Med. 2006;160(12):1277-83. (30) Steinhoff M, Omer S, Roy E, et al. Neonatal outcomes after influenza immunization during pregnancy: a randomized controlled trial. CMAJ. 2012;184(6):645-53. (31) Fell DB, Sprague AE, Liu N, et al. H1N1 influenza vaccination during pregnancy and fetal and neonatal outcomes. Am J Public

2017 CPG Infobase

186. Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada

. Prebtani MD, FRCPC, Vincent Woo MD, FRCPC S190 Management of Acute Coronary Syndromes Jean-Claude Tardif MD, FRCPC, FACC, FCAHS, Phillipe L. L'Allier MD, David H. Fitchett MD, FRCPCCONTENTS (continued): April 2018 Volume 42 Supplement 1 S196 Treatment of Diabetes in People With Heart Failure Kim A. Connelly MBBS, PhD, FCCS, Richard E. Gilbert MBBS, PhD, Peter Liu MD, FRCPC, FACC S201 Chronic Kidney Disease in Diabetes Philip McFarlane MD, PhD, FRCPC, David Cherney MD, PhD, FRCPC, Richard E. Gilbert (...) , ON Olivier F. Bertrand MD PhD Associate Professor of Medicine Quebec Heart–Lung Institute, Laval University, QC Acknowledgment / Can J Diabetes 42 (2018) A6–A16 Kim Connelly MBBS PhD Associate Professor Division of Cardiology, Department of Medicine, University of Toronto, Director, Krembil Stem Cell Facility, President, Canadian Society for Cardiac MRI, St. Michael’s Hospital, Toronto ON Michael Coons CPsych CBSM Clinical Health Psychologist Medical Bariatrics and Diabetes, St. Joseph’s Healthcare

2018 Diabetes Canada

187. Dinutuximab beta Apeiron - neuroblastoma

processing ECG Electrocardiogram ECHO Echocardiogram EEG Electroencephalogram EFS event-free survival ELISA Enzyme-linked immunosorbent assay EM(E)A European Medicines Agency EOT End of treatment EPC End of Production Cells Assessment Report - Dinutuximab beta Apeiron EMA/263814/2017 Page 5/129 ESI-TOF-MS Electrospray ionisation time-of-flight mass spectrometry FAS Full analysis set FCS Fetal calf serum Fc?R FC gamma receptor FDA Food and Drug Administration G0 Glycan without core fucose and no galactose (...) 150 kDa corresponding to the expected size of an intact IgG1, but smaller faint bands were also visible at about 100 kDa, 70kDa and 26kDa on the gels. The identity of these bands has been clarified as product-related variants of ch14.18/CHO, with only traces of HCP. Bands at 50kDa appear to contain heavy chain and two light chains, with the band at 25 kDa appearing to be mainly free light chain with low levels of HCP. Since these are all at levels well below the main band (by densitometry

2017 European Medicines Agency - EPARs

188. Zika virus and safety of substances of human origin: a guide for preparedness activities in Europe ? first update

transmission through cells, tissues and organs remains unknown. Zika virus can also be transmitted vertically from an infected mother to the foetus during pregnancy and is responsible for foetal loss, microcephaly, and other congenital neurological syndromes [9]. The incubation period ranges from 3.5 days in a human volunteer [10] to 6 to 10 days in returning travellers and blood donors [3,11,12]. Although previous reports state that 80% of Zika virus infection cases are asymptomatic [13], it seems (...) -virus associated Guillain–Barré syndrome (GBS) have not been reported. Moreover, the likelihood of maternal and foetal exposure to blood products and presumably to other SoHO is very small. Data on Zika virus infection in donors of cells, tissues and organs and transmission of the virus to the transplant recipients are lacking. Nevertheless, the clear association between Zika virus infection and congenital malformations and GBS justifies the implementation of preventive measures to reduce the risk

2017 European Centre for Disease Prevention and Control - Technical Guidance

189. Trumenba - meningococcal group b vaccine (recombinant, adsorbed)

in the final packaging process may contain trace levels of animal tallow derivatives. As tallow is processed under rigorous conditions, it is considered compliant with the TSE note for guidance. The information provided does not give rise to any concerns on adventitious agents. The absence of adventitious agents has been sufficiently demonstrated. 2.2.4. Discussion on chemical, pharmaceutical and biological aspects The quality documentation submitted in support of Trumenba was considered of good quality

2017 European Medicines Agency - EPARs

190. WHO recommendations: intrapartum care for a positive childbirth experience

for assessment of fetal well-being in healthy pregnant women undergoing spontaneous labour. Not recommended Intermittent fetal heart rate auscultation during labour 18. Intermittent auscultation of the fetal heart rate with either a Doppler ultrasound device or Pinard fetal stethoscope is recommended for healthy pregnant women in labour. Recommended Epidural analgesia for pain relief 19. Epidural analgesia is recommended for healthy pregnant women requesting pain relief during labour, depending on a woman’s (...) ), a cosponsored programme executed by the WHO. The views of the funding bodies have not influenced the content of this guideline. Editing: Green Ink, United Kingdom.vii ACRONYMS AND ABBREVIATIONS Acronyms and abbreviations ABO adverse birth outcome aOR adjusted odds ratio CERQual Confidence in the Evidence from Reviews of Qualitative research CI confidence interval cRCT cluster randomized controlled trial CTG cardiotocography DOI declaration of interest EB evidence base EtD evidence-to-decision FHR fetal

2018 World Health Organisation Guidelines

191. Improving the health of the public by 2040

and medical interventions. However, despite overall improvements in health, major inequalities in health outcomes, reflecting social and economic inequalities, persist.1. Introduction 12 • Vaccination. • Motor vehicle safety. • Safer workplaces. • Control of infectious diseases. • Decline in deaths from coronary heart disease and stroke. • Safer and healthier foods. • Healthier mothers and babies. • Family planning. • Fluoridation of drinking water. • Recognition of tobacco use as a health hazard. Box 1 (...) and in the last 50 years has increased by a further 10 years for a man and 8 for a woman. 3,4 Improvements in living conditions and large reductions in infant and child mortality were major contributors to this increase in the first half of the 20th century. Over the last 50 years, improvement has been greatest at older ages. The number of people dying from coronary heart disease, for example, in Great Britain more than halved between 1961 and 2009. 5 While improved treatments have had an important role

2017 Academy of Medical Sciences

192. Management Of Haemophilia

& Trauma Surgeon Gleneagles Hospital, Kuala Lumpur Associate Professor Dr. Azlan Husin Consultant Physician & Clinical Haematologist Hospital Universiti Sains Malaysia, Kelantan Dr. Carol Lim Kar Koong Head of Department & Consultant Obstetrician & Gynaecologist (Maternal Fetal Medicine) Hospital Sultan Ahmad Shah, Pahang Ms. Haironi Ismail Physiotherapist Hospital Putrajaya, Putrajaya Ms. Halimah Hashim Physiotherapist Hospital Raja Perempuan Zainab II, Kelantan Dr. Jalil Ishak Family Medicine (...) ): 20 mg/kg stat, then15 mg/kg every 4 - 6-hourly Max: 60 mg/kg (up to 90 mg/kg for 48 hours) Selective Cox-2 Inhibitors Celecoxib Adults (oral): 100 - 400 mg, 12 - 24-hourly Max: 800 mg/day Not recommended in severe renal and/or hepatic impairment Initiate therapy at lowest recommended dose in elderly Ischaemic heart disease Cerebrovascular disease Contraindicated in hypersensitivity to sulfonamides Associated with a lower risk of serious upper gastrointestinal side effects compared to NSAIDs

2018 Ministry of Health, Malaysia

193. Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutritio

)/factitious disorder by proxy (FDP) Hereditary fructose intolerance Child neglect or abuse Urea cycle defects Self-induced vomiting Amino and organic acidemias Cyclic vomiting syndrome Fatty acid oxidation disorders Rumination syndrome Metabolic acidosis Congenital adrenal hyperplasia/adrenal crisis Toxic Renal Lead poisoning Obstructive uropathy Other toxins Renal insuf?ciency Cardiac Heart failure Vascular ring Autonomic dysfunction ESPGHAN ¼ European Society for Pediatric Gastroenterology, Hepatology (...) indications for the performance of pH-MII in the evaluation of GERD. 1. Differentiate patients with NERD, hypersensitive esopha- gus and functional heartburn in patients with normal endoscopy. The recently published Rome IV criteria for esophageal disorders included new classi?cations for adults with typical GERD symptoms including chest pain and heart burn. In patients with persistent typical symptoms despite acid suppression, pH-MII can clarify the diagnosis of NERD (pathologic re?ux regardless

2018 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

194. The use of viscoelastic haemostatic assays in the management of major bleeding Full Text available with Trip Pro

management has been reported to improve overall clinical outcomes after cardiac surgery (Weber et al , ; Sartorius et al , ; Pearse et al , ; Trevisan et al , ), and result in less bleeding and lower need for re‐exploration after coronary artery bypass grafting (CABG) (Speiss et al , ). Duration of hospitalisation was also reduced (Ichikawa et al , ). Conversely, a recent systematic review of 15 randomised trials involving 8737 patients found no significant difference in mortality, reoperation (...) Online Library Terms and Conditions of Use. Shareable Link Use the link below to share a full-text version of this article with your friends and colleagues. Copy URL Share a link ) and 10% of cardiac surgery patients (Serraino & Murphy, ). Blood loss is one of the main causes of morbidity following liver transplantation (Gurusamy et al , ) and is one of the most common causes of death worldwide in women at the time of delivery (Say et al , ). Diagnosis of major bleeding is difficult and is often made

2018 British Committee for Standards in Haematology

196. Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy

of VTE, mechanical heart valves, and atrial fibrillation. In addition, patients with bare metal or drug-eluting coronary stents require antiplatelet therapy with aspirin and thienopyridine derivatives (eg, clopidogrel) for varying durations. These patients may present for elective or urgent surgical procedures. Perioperative management involves balancing the risks of surgical bleeding and thromboembolism. Minor procedures may not require interruption of antithrombotic or antiplatelet therapy. However (...) . In other patients, bridging anticoagulation with UFH or LMWH is required until the time of surgery (and reinitiated in the immediate postoperative period). It may also be necessary to postpone elective surgeries in patients where a suitable “bridge” has not been identified and antithrombotic therapy is critical; premature discontinuation of dual antiplatelet therapy in patients with coronary stents has been associated with stent thrombosis, myocardial infarction, and death ( and ). Evidence-based

2018 American Society of Regional Anesthesia and Pain Medicine

197. Antithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report

. For patients with AF and stable coronary artery disease (eg, no acute coronary syndrome within the previous year) and who choose oral anticoagulation, we suggest OAC with either an NOAC or adjusted- dose VKA therapy alone (target international normalized ratio [INR] range, 2.0-3.0) rather than the combination of OAC and aspirin (Weak recommendation, low quality evidence). 32. In patients with AF in whom catheter ablation of AF or implantation of cardiac electronic implantable devices is planned, we suggest (...) and signpost the patient to appropriate educational resources. Introduction Atrial ?brillation (AF) is the most common sustained cardiac arrhythmia, with an increasing prevalence and incidencewithage.Inadultsaged>40years,thereisa1 in 4 lifetime risk of developing AF, with incident AF commonly related to various associated cardiovascular and noncardiovascular risk factors. AF without associated valvular heart disease (so-called “nonvalvular AF”) is associated with a ?vefold increase in stroke risk

2018 American College of Chest Physicians

198. CRACKCast E180 – Labor & Delivery

, the strength of the contractions correlates poorly with the tracing. The tracings are position and placement sensitive. Fetal heart rate tracings have several components that can be assessed—baseline heart rate, variability, accelerations, decelerations, and diagnostic patterns. Ultrasonography the gestational age, biophysical profile, amniotic fluid index, and a survey of fetal and placental anatomy may be obtained. What are the indications for foetal monitoring during labour? -> Labouring woman 4 (...) information, limited assistance with intrapartum decision making External electronic fetal monitoring uses tracings of the fetal heart rate and uterine activity. helps confirm true labor and may help diagnose fetal distress. In combination with clinical data, this can portend fetal distress due to hypoxia and provide a window for intervention. Uterine activity is measured transabdominally by a pressure transducer, creating a recording of the contraction frequency. Because the measurements are indirect

2018 CandiEM

200. Preterm labour and birth

blood cell count and measurement of fetal heart rate using cardiotocography) to diagnose intrauterine infection in women with P-PROM. 1.5.2 Do not use any one of the following in isolation to confirm or exclude intrauterine infection in women with P-PROM: a single test of C-reactive protein white blood cell count measurement of fetal heart rate using cardiotocography. 1.5.3 If the results of the clinical assessment or any of the tests are not consistent with each other, continue to observe the woman (...) reducing the dose of magnesium sulfate. 1.11 Fetal monitoring Monitoring options: cardiotocogr Monitoring options: cardiotocograph aphy and intermittent auscultation y and intermittent auscultation 1.11.1 Discuss with women in suspected, diagnosed or established preterm labour (and their family members or carers as appropriate): the purpose of fetal monitoring and what it involves the clinical decisions it informs at different gestational ages if appropriate, the option not to monitor the fetal heart

2015 National Institute for Health and Clinical Excellence - Clinical Guidelines

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