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Fetal Head Circumference

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81. Environmental exposures and fetal growth: the Haifa pregnancy cohort study. Full Text available with Trip Pro

Environmental exposures and fetal growth: the Haifa pregnancy cohort study. The developing fetus is susceptible to environmental insults. Studying the effects of environmental exposures on fetal growth is essential for understanding the causal pathway between prenatal exposures and pregnancy outcomes. Here we describe the Haifa Pregnancy Cohort Study (HPCS) and discuss challenges and opportunities in applying "big data" paradigm.Maccabi Healthcare Services (MHS), is the second largest Israeli (...) such as birth-weight, head-circumference and gestational age at birth. We will adjust for pregnancy complications such as pre-eclampsia and gestational diabetes and parental variables, such as maternal weight, age and smoking habits as potential confounders. In addition, we will conduct a multi-tiered field study, nested within this population, among 150 pregnant women residing in two geographical regions-one in the polluted Haifa area, and one in a relatively unpolluted area in central Israel. Blood

2018 BMC Public Health

82. The mediating effects of gestational diabetes on fetal growth and adiposity in women who are overweight and obese: secondary analysis of the LIMIT randomised trial. Full Text available with Trip Pro

gestation.Fetal ultrasound measures at 36 weeks of gestation and baseline BMI from women randomised to the LIMIT trial Standard Care group (n = 912 women) were used to conduct causal mediation analyses using regression-based methods.Ultrasound measures of fetal biometry and adiposity at 36 weeks of gestation.Increased maternal BMI was associated with increased measures of fetal head circumference [direct (unmediated) effect 0.18 (95% CI: 0.05-0.31), P = 0.005; total effect 0.17 (95% CI: 0.02-0.31), P = 0.018 (...) ], abdominal circumference [direct effect 0.26 (95% CI: 0.11-0.41), P = 0.001; total effect 0.26 (95% CI: 0.11-0.42), P = 0.001] and estimated fetal weight [direct effect 0.22 (95% CI: 0.08-0.35), P = 0.002; total effect 0.22 (95% CI: 0.08-0.35), P = 0.002], with no evidence of mediation by treated gestational diabetes. There was no apparent association between maternal BMI and fetal adiposity measures, or mediation by treated gestational diabetes.We show an important association between increased maternal

2018 BJOG Controlled trial quality: uncertain

83. Femur-Sparing Pattern of Abnormal Fetal Growth in Pregnant Women from New York City After Maternal Zika Virus Infection. Full Text available with Trip Pro

for the 21st Century Project and World Health Organization Fetal Growth Chart sonographic standards were applied to obtain Z-scores and/or percentiles for fetal head circumference, abdominal circumference, and femur length specific for each gestational week. A novel 2014 International Fetal and Newborn Growth Consortium for the 21st Century Project standard was also developed to generate Z-scores for fetal body ratios with respect to femur length (head circumference:femur length, abdominal (...) circumference:femur length). Data were then grouped within clinically relevant gestational age strata (<24, 24-27 6/7, 28-33 6/7, >34 weeks) to analyze time-dependent effects of Zika virus infection on fetal size. Statistical analysis was performed using Wilcoxon signed-rank test on paired data, comparing either abdominal circumference or head circumference to femur length.A total of 56 pregnant women were included in the study with laboratory evidence of a confirmed or possible recent Zika virus infection. Based

2018 American Journal of Obstetrics and Gynecology

84. Fetal growth velocity and body proportion in the assessment of growth. Full Text available with Trip Pro

and interval between exams. The second strategy refers to the use of fetal body proportions to classify fetuses as either symmetric or asymmetric using 1 of several ratios; these include the head circumference to abdominal circumference ratio, transverse cerebellar diameter to abdominal circumference ratio, and femur length to abdominal circumference ratio. Although these ratios are associated with small for gestational age at birth and with adverse perinatal outcomes, their predictive accuracy is too low (...) Fetal growth velocity and body proportion in the assessment of growth. Fetal growth restriction implies failure of a fetus to meet its growth potential and is associated with increased perinatal mortality and morbidity. Therefore, antenatal detection of fetal growth restriction is of major importance in an attempt to deliver improved clinical outcomes. The most commonly used approach towards screening for fetal growth restriction is by means of sonographic fetal weight estimation, to detect

2018 American Journal of Obstetrics and Gynecology

85. Sensorimotor Outcomes of Children Exposed to Foetal Zika Virus Infection

Scale (AIMS - prone, supine, sitting, standing, total score and corresponding percentile) and Gross Motor Function Measure (GMFM, A: lying/rolling and B: sitting). Head circumference at birth and on the day of assessment (in cm), age (in months) and family income, as well as AIMS and GMFM scores, provided as means, standard deviations, and minimum and maximum scores. Qualitative data about sex, muscle tone (increased, decreased or normal), visual/ hearing impairments (yes or no) were also collected (...) control. [ Time Frame: 1 month ] Sensorimotor outcomes was assessed by using Alberta Infant Motor Scale (AIMS) Secondary Outcome Measures : Children whose mothers were affected in the first trimester had lower head circumference measures that children whose mothers were affected in the second trimester. [ Time Frame: 1 month ] Assessment of birth head circumference. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal

2018 Clinical Trials

86. Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort. Full Text available with Trip Pro

10,705 singletons (4747 White European and 5958 South Asian) from a prospective cohort of women attending an antenatal clinic in Bradford, in the North of England. All women completed a 75-g oral glucose tolerance test at 26-28 weeks' gestation. Ultrasound measurements of fetal head circumference (HC), femur length (FL) abdominal circumference (AC), and estimated fetal weight (EFW), and corresponding anthropometric measurements at birth were used to derive fetal growth trajectories. Associations (...) Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort. Maternal gestational diabetes (GDM) is an established risk factor for large size at birth, but its influence on intrauterine fetal growth in different ethnic populations is less well understood. Here, we examine the joint associations of GDM and ethnicity with longitudinal fetal growth in South Asian and White European origin women.This study included

2018 BMC Medicine

87. Foetal weight prediction models at a given gestational age in the absence of ultrasound facilities: application in Indonesia. Full Text available with Trip Pro

at a given gestational age was assessed using multi-prediction accuracy measures.Four weight prediction models based on fundal height and its combinations with gestational age (between 32 and 41 weeks) and ultrasonic estimates of foetal head circumference and foetal abdominal circumference have been developed. Multiple comparison criteria show that the proposed models were more accurate than the existing models (mean prediction errors between - 0.2 and 2.4 g and median absolute percentage errors between (...) Foetal weight prediction models at a given gestational age in the absence of ultrasound facilities: application in Indonesia. Birth weight is one of the most important indicators of neonatal survival. A reliable estimate of foetal weight at different stages of pregnancy would facilitate intervention plans for medical practitioners to prevent the risk of low birth weight delivery. This study has developed reliable models to more accurately predict estimated foetal weight at a given gestation age

2018 BMC Pregnancy and Childbirth

88. Development of an Epigenetic Biomarker for Prediction of Fetal Alcohol Spectrum Disorder

hours post birth ] To compare PEth levels and epigenetic changes in dried blood spots obtained via umbilical cord at birth verses heel stick at 48 hours post-birth. Other Outcome Measures: Gestational age at birth [ Time Frame: at birth ] Small for gestational age: composite of small for gestational age (<10% percentile) for weight or length or head circumference [ Time Frame: at birth ] Postnatal complications: Composite of having one or more of the following: neonatal sepsis, necrotizing (...) Development of an Epigenetic Biomarker for Prediction of Fetal Alcohol Spectrum Disorder Development of an Epigenetic Biomarker for Prediction of Fetal Alcohol Spectrum Disorder - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2018 Clinical Trials

89. Fetal growth restriction in rural Bangladesh: a prospective study Full Text available with Trip Pro

Fetal growth restriction in rural Bangladesh: a prospective study Fetal growth restriction (FGR) and low birth weight(LBW) are serious public health problems. In developing countries, the incidence of low birth weight is predominantly the result of FGR, and both low birth weight and FGR are associated with neonatal death and later growth and development. Fetal growth charts are important for assessing the size of the fetus during pregnancy. The aims of this study were to describe the fetal (...) growth pattern of a population in rural Bangladesh where maternal undernutrition is prevalent and to compare the timing of FGR in that population with WHO and INTERGROWTH- 21st international reference values.From November 2001 to October 2003, pregnant women were recruited in Matlab, a sub district of Bangladesh, and underwent three follow-up ultrasound examinations during pregnancy for measurement of the parameters of the fetal head, abdomen, and femur. The data were fitted to a linear-cubic model

2018 Tropical medicine and health

90. Visfatin as a predictor for growth of fetus and infant Full Text available with Trip Pro

weeks of gestation using ELISA.The infants were followed up for a mean duration of 10.19±2.83 months. In group A, there was a strong positive relationship between birth head circumference and the first (p1=0.054, r1=0.580) and second trimester visfatin levels (p2=0.051, r2=0.530). In group B, second trimester visfatin levels correlated negatively with birth length (p=0.015, r=-0.523) and infant's head circumference (p2=0.050, r2=-0.392). In a separate study on group B, visfatin levels in the first (...) Visfatin as a predictor for growth of fetus and infant Visfatin is an adipocytokine that functions as an enzyme and a growth factor to investigate the relationship between serum visfatin and the fetus's anthropometric markers up to a year after birth.Forty-one eligible pregnant women in their first trimester were divided and matched in terms of body mass index (BMI) before pregnancy into normal and higher than normal BMI groups, A and B. Serum visfatin levels were measured during 6-12 and 15-20

2018 Turkish Journal of Obstetrics and Gynecology

91. WHO Fetal Growth Charts

with retarded growth Device: ultrasound The compulsory ultrasound measurements to be obtained at all visits include the following biometrical parameters: Biparietal diameter Head circumference Abdominal circumference Femur length Humerus length Outcome Measures Go to Primary Outcome Measures : Proportion of fetuses with abnormal fetal growth diagnosed using WHO fetal charts [ Time Frame: 8 months ] correlation of fetal growth pattern with neonatal birth weight and outcome Eligibility Criteria Go (...) in Assiut,Egypt Estimated Study Start Date : January 2019 Estimated Primary Completion Date : January 2020 Estimated Study Completion Date : May 2020 Groups and Cohorts Go to Group/Cohort Intervention/treatment normal group fetuses with normal growth Device: ultrasound The compulsory ultrasound measurements to be obtained at all visits include the following biometrical parameters: Biparietal diameter Head circumference Abdominal circumference Femur length Humerus length Growth retardation group fetuses

2018 Clinical Trials

92. Comparison of the Hadlock and INTERGROWTH 21<sup>st</sup> formulas for calculating estimated fetal weight in a preterm population in France. (Abstract)

the EPIPAGE 2 population-based study of births between 22-34 weeks of gestation, we included 578 nonanomalous singleton fetuses with an ultrasound-to-delivery interval <2 days. We used abdominal circumference, head circumference, and femur length to calculate estimated fetal weight with Hadlock formula and abdominal and head circumferences to calculate estimated fetal weight according to INTERGROWTH. The mean percentage errors and the proportions of estimated fetal weight measures within ±10 (...) Comparison of the Hadlock and INTERGROWTH 21st formulas for calculating estimated fetal weight in a preterm population in France. Accurate estimation of fetal weight is needed for growth monitoring and decision-making in obstetrics; the INTERGROWTH project developed an estimated fetal weight formula to construct new intrauterine growth standards.We sought to compare the accuracy of the Hadlock and INTERGROWTH formulas for the estimation of fetal weight among preterm infants.Using

2018 American Journal of Obstetrics and Gynecology

93. Ultrasonographic estimation of fetal weight: development of new model and assessment of performance of previous models. Full Text available with Trip Pro

Euclidean distance and highest proportion of AE ≤ 10%, were provided by the formulae incorporating ≥ 3 rather than < 3 biometrical measurements. The systematic review identified 45 studies describing a total of 70 models for EFW by various combinations of measurements of fetal head circumference (HC), biparietal diameter, femur length (FL) and abdominal circumference (AC). The most accurate model with the lowest Euclidean distance and highest proportion of AE ≤ 10% was provided by the formula of Hadlock (...) Ultrasonographic estimation of fetal weight: development of new model and assessment of performance of previous models. To develop a new formula for ultrasonographic estimation of fetal weight and evaluate the accuracy of this and all previous formulae in the prediction of birth weight.The study population consisted of 5163 singleton pregnancies with fetal biometry at 22-43 weeks' gestation and live birth of a phenotypically normal neonate within 2 days of the ultrasound examination

2018 Ultrasound in Obstetrics and Gynecology

94. Abnormal fetal cerebral and vascular development in hypoplastic left heart syndrome. Full Text available with Trip Pro

and control fetuses without heart disease.Twenty-seven midgestation fetal HLHS were included (gestational age, 23.3 ± 3.4 weeks). Head circumference z scores were lower in HLHS fetuses. Middle cerebral artery pulsatility index, a measure of cerebrovascular resistance, was inversely correlated with the ascending aortic z score (P < 0.05). Fetuses with HLHS had lower capillary density in the germinal matrix and their capillaries were larger compared with control fetuses with (P < 0.05). The expression (...) Abnormal fetal cerebral and vascular development in hypoplastic left heart syndrome. To assess the cerebral and vascular development in fetuses with hypoplastic left heart syndrome (HLHS).Pregnant women carrying fetuses diagnosed with HLHS who decided to interrupt their pregnancies were included in our study. Aortic size and blood flow were assessed based from fetal echocardiography. Immunohistochemical staining was performed in brain sections obtained from pathology in fetuses with HLHS

2018 Prenatal diagnosis

95. Head Circumference

Head Circumference Head Circumference Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Head Circumference Head Circumference Aka: Head (...) Circumference , Microcephaly , Microcephalic Infant , Macrocephaly , Macrocephalic Infant II. Exam: Head Size Measurement Normal term newborn Head Circumference: 33 to 38 cm Technique Measuring tape around frontal forehead and occiput Take largest of several measurements III. Causes: Macrocephaly Familial with inheritance Other conditions (skeletal dysplasia) Sotos' Syndrome ( ) Alexander's Disease Canavan's Disease Gangliosidoses Glutaric aciduria Type I Type I IV. Causes: Microcephaly Familial Trisomy 13

2015 FP Notebook

96. Diet, weight gain, and head growth in hospitalized US very preterm infants: a 10-year observational study. (Abstract)

(no formula or fortifier); 2) human milk with formula or fortifier (mixed); or 3) infant formula only. Outcomes were weight and head circumference z-score change from birth to discharge relative to a fetal reference.Diet at discharge/transfer was human milk only for 18,274 (6.6%), mixed for 121,621 (44%), and formula only for 137,067 (49%). Weight deviated more from the fetal reference for infants fed both human milk diets compared with formula only (weight z-score change for infants fed human milk only (...) Diet, weight gain, and head growth in hospitalized US very preterm infants: a 10-year observational study. The benefits of human milk for hospitalized preterm infants are well documented, but the extent to which current human milk diets adequately support growth is uncertain.1) To quantify differences in weight gain and head growth between very preterm infants fed human milk compared with infant formula; and 2) to describe trends in the magnitude of these differences over time.We studied

2019 American Journal of Clinical Nutrition

97. The role of additional pathology on head growth patterns in fetuses with congenital heart defects. Full Text available with Trip Pro

The role of additional pathology on head growth patterns in fetuses with congenital heart defects. Neurodevelopmental delay is frequently encountered in children with a congenital heart defect (CHD). Fetuses with major CHD have a smaller head circumference (HC), irrespective of altered cerebral flow or brain oxygenation. This cohort study compared head growth in cases with isolated vs those with non-isolated CHD to evaluate the effect of additional pathology on head size in these fetuses.All (...) CHD cases diagnosed prenatally in the period January 2002-July 2014 were selected from our regional registry, PRECOR. Cases of multiple pregnancy, and those affected by maternal diabetes, severe fetal structural brain anomalies or functional CHD were excluded. Subjects were divided into groups according to whether the CHD was isolated, and the non-isolated group was subdivided into three groups: cases with genetic anomaly, extracardiac malformation or placental pathology. In both isolated and non

2019 Ultrasound in Obstetrics and Gynecology

98. Outcomes of fetuses with small head circumference on second-trimester ultrasonography. (Abstract)

Outcomes of fetuses with small head circumference on second-trimester ultrasonography. We examined the outcomes of pregnancies in which the fetal head circumference (HC) was below the 5(th) centile at the routine second-trimester scan.We retrospectively analysed outcomes of 18,377 women according to HC Z scores at second-trimester ultrasound examination between 2001 and 2008. We collected all major malformations, intrauterine deaths and other abnormal outcomes.Six hundred seventy-four fetuses (...) to -1.645, compared with 0.3% of fetuses with normal HC (p < 10(-4)).A head circumference below the 5(th) centile at second-trimester scan is associated with various abnormalities, especially neurological disorders. The outcome was worse when the HC was smaller. An HC Z score below -2.5 was strongly associated with neurological and chromosomal abnormalities. Conversely, an HC Z score below -1.645 but above -2, excluding cases with prenatally diagnosed malformations, seems to be reassuring for favorable

2012 Prenatal diagnosis

99. Diagnosis and Treatment of Fetal Cardiac Disease Full Text available with Trip Pro

disease. Conclusions— Fetal cardiac medicine has evolved considerably over the past 2 decades, predominantly in response to advances in imaging technology and innovations in therapies. The diagnosis of cardiac disease in the fetus is mostly made with ultrasound; however, new technologies, including 3- and 4-dimensional echocardiography, magnetic resonance imaging, and fetal electrocardiography and magnetocardiography, are available. Medical and interventional treatments for select diseases (...) the goal has become to understand the fetus as a patient, knowing that the fetal circulation is different from the postnatal circulation, that structural disease may progress in utero, and that cardiac function and stability of the cardiovascular system play an important role in fetal wellness. Given the expanded roles of the pediatric cardiologist specializing in fetal medicine and the maternal fetal specialist as collaborative caregivers for fetuses with structural heart disease, arrhythmias

2014 American Heart Association

100. Neonatal head circumference and the treatment of maternal hypertension. (Abstract)

between neonatal head circumference and the total amount or duration of methyldopa received during pregnancy. Comparison of treated and untreated groups according to the time of entry to the study showed that significant differences in neonatal head circumference were only present in patients who entered between 16 and 20 weeks gestation. It is possible that this could be a sensitive period for the interaction of fetal head growth and the onset of specific treatment in hypertensive pregnancy. (...) Neonatal head circumference and the treatment of maternal hypertension. In a random controlled trial of methyldopa for the treatment of hypertension in pregnancy presenting before 28 weeks gestation, the newborn in the treated group had relatively smaller head circumferences. This difference persisted at two months of age when correction had been made for birth weight, gestation and sex, but was no longeer detectable at six or twelve months. Within the treated group no relationship was found

1978 British journal of obstetrics and gynaecology Controlled trial quality: uncertain

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