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Fetal Foot Measurement

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741. Diabetes mellitus type 2 Full Text available with Trip Pro

The development of type 2 diabetes is caused by a combination of lifestyle and genetic factors. While some of these factors are under personal control, such as and , other factors are not, such as increasing age, female gender, and genetics. Obesity is more common in women than men in many parts of Africa. A lack of sleep has been linked to type 2 diabetes. This is believed to act through its effect on . The status of a mother during fetal development may also play a role, with one proposed mechanism being (...) , as they are more convenient for people. HbA 1c has the advantages that fasting is not required and results are more stable but has the disadvantage that the test is more costly than measurement of blood glucose. It is estimated that 20% of people with diabetes in the United States do not realize that they have the disease. Diabetes mellitus type 2 is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency. This is in contrast to in which there is an absolute

2012 Wikipedia

742. Diabetes mellitus Full Text available with Trip Pro

. Prevention and treatment involve maintaining a , regular , a normal body weight, and avoiding . Control of and maintaining proper foot care are important for people with the disease. Type 1 DM must be managed with . Type 2 DM may be treated with with or without insulin. Insulin and some oral medications can cause . in those with is sometimes an effective measure in those with type 2 DM. Gestational diabetes usually resolves after the birth of the baby. As of 2017 , an estimated 425 million people had (...) changes, blood glucose monitoring, and in some cases, insulin may be required. Though it may be transient, untreated GDM can damage the health of the fetus or mother. Risks to the baby include (high birth weight), and abnormalities, and malformations. Increased levels of insulin in a fetus's blood may inhibit fetal production and cause . A may result from . In severe cases, perinatal death may occur, most commonly as a result of poor placental perfusion due to vascular impairment. may be indicated

2012 Wikipedia

743. Leonardo da Vinci

fuse art and (the forerunner of modern science). They were made and maintained daily throughout Leonardo's life and travels, as he made continual observations of the world around him. A page showing Leonardo's study of a foetus in the womb ( Leonardo's notes and drawings display an enormous range of interests and preoccupations, some as mundane as lists of groceries and people who owed him money and some as intriguing as designs for wings and shoes for walking on water. There are compositions (...) . They include , a , hydraulic pumps, reversible crank mechanisms, finned mortar shells, and a . In 1502, Leonardo produced a drawing of a single span 720-foot (220 m) bridge as part of a civil engineering project for Ottoman of . The bridge was intended to span an inlet at the mouth of the known as the . Beyazid did not pursue the project because he believed that such a construction was impossible. Leonardo's vision was resurrected in 2001 when a based on his design was constructed in Norway. Leonardo

2012 Wikipedia

744. Lead poisoning

Lead poisoning Lead poisoning - Wikipedia Lead poisoning From Wikipedia, the free encyclopedia Poisoning by lead in the body, especially affects the brain Lead poisoning Other names Plumbism, colica pictorum, saturnism, , painter's colic An X ray demonstrating the characteristic finding of lead poisoning in humans—dense lines. Symptoms , abdominal pain, , headaches, irritability, memory problems, , in the hands and feet , , Causes Exposure to via contaminated air, water, dust, food, consumer (...) products Being a child , , , Prevention Removing lead from the home, improved monitoring in the workplace, laws that ban lead in products Treatment Medication , , Deaths 540,000 (2016) Lead poisoning is a type of caused by in the body. The is the most sensitive. Symptoms may include abdominal pain, , headaches, irritability, memory problems, , and in the hands and feet. It causes almost 10% of of otherwise unknown cause and can result in behavioral problems. Some of the effects are permanent. In severe

2012 Wikipedia

745. Surgery

right – an entitlement to protective healthcare. Woven through the International Human and Health Rights literature is the right to be free from surgical disease. The 1966 ICESCR Article 12.2a described the need for "provision for the reduction of the stillbirth-rate and of infant mortality and for the healthy development of the child" which was subsequently interpreted to mean “requiring measures to improve… emergency obstetric services”. Article 12.2d of the ICESCR stipulates the need (...) surgery [ ] The discipline of surgery was put on a sound, scientific footing during the in Europe. An important figure in this regard was the Scottish surgical scientist, , generally regarded as the father of modern scientific surgery. He brought an and approach to the science and was renowned around Europe for the quality of his research and his written works. Hunter reconstructed surgical knowledge from scratch; refusing to rely on the testimonies of others, he conducted his own surgical experiments

2012 Wikipedia

746. GORE VIABAHN® Versus Plain Old Balloon Angioplasty (POBA) for Superficial Femoral Artery (SFA) In-Stent Restenosis

old balloon angioplasty (POBA). In 4 Belgian and 2 German centers a total of 80 Patients will be recruited. Primary endpoint is primary patency at 12 months, defined as no evidence of restenosis or occlusion within the originally treated lesion based on color-flow duplex ultrasound (CFDU) measuring a peak systolic velocity ratio ≤2.5, and without target lesion revascularization (TLR) within 12 months. In comparison to POBA, it is expected that the use of the Viabahn endoprosthesis (W.L. Gore (...) : Endoprosthesis GORE VIABAHN® Endoprosthesis Device: GORE VIABAHN® Endoprosthesis GORE VIABAHN® Endoprosthesis Active Comparator: Plain old balloon angioplasty Plain old balloon angioplasty Device: Plain old balloon angioplasty Plain old balloon angioplasty Outcome Measures Go to Primary Outcome Measures : Primary patency at 12 months, defined as no evidence of restenosis or occlusion within the originally treated lesion based on color-flow duplex ultrasound (CFDU) and without target lesion revascularization

2010 Clinical Trials

747. To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

, but more research is needed to determine its use in children. There has been one previous small study of Marqibo(Registered Trademark) in children. Although some anti-cancer activity was seen, side effects and optimal dosing were not fully determined. As is seen with standard Vincristine suflate, the most common side effect of Marqibo(Registered Trademark) involves the nervous system. It can cause numbness and tingling in the hands and feet. Symptoms commonly improve when the drug is discontinued (...) Trademark). To define the tolerability and potential activity of Marqibo(Registered Trademark) in children and adolescents with relapsed or refractory acute lymphoblastic leukemia (ALL) at the pediatric MTD. ELIGIBILITY - Children and adolescents (greater than or equal to 2 years and < 21 years of age) with histologically confirmed relapsed or refractory malignant disease that is measurable or evaluable. DESIGN Marqibo(Registered Trademark) will be administered intravenously over 60 minutes (+ or -10

2010 Clinical Trials

748. Comparison of Ultrasound Guided Low Epidural Catheter Placement With Standard Epidural Catheter Placement

. The extent of block before the surgery will be evaluated at 30 minutes post injection. Dermatomal level will be assessed on each side using ice. S1 and S2 dermatomal blockage will be specifically assessed on each side by testing lateral margin of each foot (S1 dermatome) and medial side of the popliteal fossa ( S2 dermatome). Thereafter catheter will be connected to epidural solution containing 0.1% bupivacaine and 2 mic of Fentanyl per ml. Starting dose will be 10 ml per hr with bolus dose 5 ml q 30 (...) by the National Library of Medicine related topics: Groups and Cohorts Go to Group/Cohort Ultrasound L5/S1 catheter placement Pt will have back scanned with Ultrasound and L5/S1 interspace localized for epidural placement. Control Group Patients will have catheter placed after clinically evaluating the back as is done routinely resulting in mid lumbar catheter placement in general. Outcome Measures Go to Primary Outcome Measures : 1.Blocking of S1 and S2 dermatomes [ Time Frame: 30 minutes after loading

2010 Clinical Trials

749. The Use of Bioscaffolds in Conjunction With Negative Pressure Therapy: A Prospective Randomized Double-Blinded Trial

: October 26, 2010 Last Update Posted : May 17, 2016 Sponsor: Integra LifeSciences Corporation Collaborator: Beth Israel Deaconess Medical Center Information provided by (Responsible Party): Integra LifeSciences Corporation Study Details Study Description Go to Brief Summary: The primary aim of this study proposal is to test an innovative form of fetal bovine dermis bioscaffold in combination with negative pressure wound therapy (NPWT) to enhance wound healing in diabetic foot ulcers. Condition (...) Actual Primary Completion Date : January 2013 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Experimental Arm (Internal Control) One-half of ulcer receives negative pressure wound therapy One-half of ulcer receives a fetal bovine collagen bioscaffold (PriMatrix, TEI Biosciences, Boston, MA) in addition to the same negative pressure wound therapy Device: PriMatrix Dermal Repair Scaffold Outcome Measures

2010 Clinical Trials

750. Ephedrine vs Phenylephrine

that has no impact on physical activity ) Exclusion Criteria: Circulatory disease (eg pre-existing hypertension) Cardiac disease/medications (e.g. angina, cardiomyopathy, B Blocker medication) Pregnancy related disease (eg pre-eclampsia) Diabetes pre-existing the pregnancy Hyperthyroidism Renal Disease Closed-angle glaucoma Patients on monoamine oxidase inhibitors In active labour Emergency caesarean section Fetal abnormalities Contraindications to spinal anaesthesia Height >6 feet/180cm / Height <5 (...) ). Birth should occur more or less 10-15 minutes after beginning surgery, so this is approximatively 30 minutes after spinal anaesthetic. It is very unlikely that the infusion will run continuously and exceed 120mg. Outcome Measures Go to Primary Outcome Measures : ST segment changes on Holter monitoring [ Time Frame: 30 minutes pre spinal anaesthesia to 4 hours post delivery ] Secondary Outcome Measures : Troponin levels [ Time Frame: 24h post delivery ] Incidence of maternal low systolic blood

2010 Clinical Trials

751. Exploring the Causes of Clubfoot Using Magnetic Resonance Imaging, MRI

Resonance Imaging (MRI) of calf and foot Detailed Description: Clubfoot is a medical condition of the foot known to doctors as "Congenital Talipes Equinovarus (CTEV)", which affects at least 2 per 1000 Scottish births (ISD data). Affected babies are born with one or both feet in an abnormal position. Treatment with plaster casts, and occasionally with surgery, is necessary to get the foot into a normal position. We know from our animal and clinical studies and published work that the normal processes (...) of development of the foot continue through pregnancy and postnatally. Clubfoot has never been studied by MRI antenatally in humans, and examination of the foot before birth may offer aetiological clues, not apparent from a single postnatal scan. Additionally, robust information that will help to understand which features of clubfoot in utero predict a truly affected fetus could be very useful for the clinical care of those suspected to be affected at a 20 week scan. This study will provide preliminary data

2010 Clinical Trials

752. Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients

measurements of vital signs will be taken. Otherwise standard management will then be used: Patients must be NPO for 8 hours Pulse oximetry, EKG monitoring, noninvasive blood pressure at a minimum of every 3 minutes, more frequently if decided by the provider. Standard lumbar puncture in a sitting position the L3-L4 or L4-L5 Whitacre pencil-point, 25 gauge Injectate: 2 mL of 0.75% hyperbaric bupivacaine, 100 mcg preservative free morphine, 20 mcg fentanyl Immediately after completing the subarachnoid (...) injection, patients will be laid supine with left lateral uterine displacement The sensory level of anesthesia will be assessed in the standard fashion every five minutes using ice. The motor component will tested using the Bromage scale for spinal anesthesia (0, no paralysis; 1, inability to lift the thigh [only knee/feet]; 2, inability to flex the knee [only feet]; 3, inability to move any joint in the legs). Condition or disease Intervention/treatment Phase Hypotension Pregnancy Drug: ondansetron

2010 Clinical Trials

753. Intravenous (IV) Nitroglycerin for Versions in Multiparous Women

, with further doses of 1-3mL, up to a recommended maximum of 10mL. Outcome Measures Go to Primary Outcome Measures : Success of ECV (if fetus turned from Breech to cephalic) at end of ECV procedure [ Time Frame: Recorded at the end of ECV attempt ] Secondary Outcome Measures : Success of ECV (ie fetus in cephalic presentation) recorded at time of delivery [ Time Frame: Recorded at time of birth ] Mode of delivery [ Time Frame: Recorded at time of birth ] Maternal side effects and adverse events [ Time Frame (...) Study Description Go to Brief Summary: Breech presentations (where a baby presents with feet or bottom down) have an increased risk of perinatal and neonatal complications, and are usually delivered by cesarean section. As an alternative, so that the baby can be delivered vaginally, an attempt can be made to turn the baby so that it is head down: this manoeuvre is called an external cephalic version (ECV). Drugs that relax the uterus (tocolytic agents) are sometimes used to help improve ECV success

2009 Clinical Trials

754. Gestational Age is Underestimated by Menstrual Dating Compared to Ultrasound Dating in Those Undergoing Abortion up to 20 Weeks

of conception, and fetal foot length if available. Further we will record associated factors such as contraception at time of conception, intravenous drug use, and regularity of menstrual cycle. We will calculate the gestational age at time of abortion by the LMP date, by the ultrasound date reported, ultrasound date based on the Hadlock protocol by the reported CRL and similarly BPD as well as calculating the gestational age based on the recorded fetal foot length. Study Design Go to Layout table for study (...) abortions between January first 2002 and June 30, 2008 inclusive at two abortion clinics in Vancouver, British Columbia: BC Women's Hospital CARE program, and the Elizabeth Bagshaw Women's Clinic. Specifically we will record age, parity, date of LMP, presence of regular cycles, ultrasound estimation of gestational age, ultrasound measurements: crown rump length, bi-parietal diameter, gestational sac diameter if available, date of abortion, estimation of gestational age by examination of the products

2009 Clinical Trials

755. Evaluation of the Cryopreserved Amniotic Membranes in the Care of Resistant Vascular Ulcers

and Interventions Go to Arm Intervention/treatment Experimental: amniotic membranes Procedure: amniotic membranes The amniotic membrane is taken with a sterile crowbar then applied side foetal face against the ulcer and displayed in a homogeneous way Outcome Measures Go to Primary Outcome Measures : Measure of the diameter of the ulcer [ Time Frame: Every week ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk (...) on the ulcer after serological checking and changed once a week. Main criterias: Tolerance will be evaluated on clinical criterias. Efficiency will be evaluated by measuring reduction of ulcer's area (reduction of at least 50 % at 6 months). Secondary criterias: Reduction of pain will be evaluated by analogic visual scale and evaluation of analgesic consumption. Evaluation of infections, amputations, complete healing, improvement of quality of life by SF36 questionnaire and recurrence at one year

2009 Clinical Trials

756. Intravenous (IV) Nitroglycerin for Versions in Nulliparous Women

injection, initial dose of 1ml, with further doses of 1-3mL, up to a recommended maximum of 10mL Outcome Measures Go to Primary Outcome Measures : Success of ECV (ie fetus turned from Breech to cephalic) at the end of ECV procedure [ Time Frame: Recorded at finish of ECV attempt ] Secondary Outcome Measures : Success of ECV (ie fetus in cephalic presentation) at time of delivery [ Time Frame: Recorded at time of birth ] Mode of delivery [ Time Frame: Recorded at time of birth ] Maternal side effects (...) Study Description Go to Brief Summary: Breech presentations (where a baby presents with feet or bottom down) have an increased risk of perinatal and neonatal complications, and are usually delivered by cesarean section. As an alternative, so that the baby can be delivered vaginally, an attempt can be made to turn the baby so that it is head down: this manoeuvre is called an external cephalic version (ECV). Drugs that relax the uterus (tocolytic agents) are sometimes used to help improve ECV success

2009 Clinical Trials

757. Age determination enhanced by embryonic foot bud and foot plate measurements in relation to Carnegie stages, and the influence of maternal cigarette smoking. Full Text available with Trip Pro

and alcohol consumption influence embryonic and fetal foot growth is also lacking.Embryonic tissue from 102 first-trimester legal abortions (aged 35-69 days p.c.) were collected. All women answered a questionnaire concerning smoking and drinking habits, and delivered a urine sample for cotinine analysis. Embryonic age was evaluated by vaginal ultrasound measurements and by post-termination foot length and compared with the Carnegie stages.Foot bud and foot plate were defined and measured as foot length (...) in embryos aged 35-47 days p.c. (range 0.8-2.1 mm). In embryos and fetuses aged 41-69 days p.c., heel-toe length was measured (range 2.5-7.5 mm). We found a significant linear correlation between foot length and age. Morphology of the feet was compared visually with the Carnegie collection, and we found that the mean ages of the two collections correlated well. Foot length was independent of gender, Environmental Tobacco Smoke, maternal smoking and alcohol consumption.Foot length correlated linearly

2009 Human Reproduction

758. Iodine

along with compression therapy seems help heal leg ulcers and reduce the chance of a future infection. Possibly effective for... Conjunctivitis (pinkeye) . Research suggests that using eye drops containing iodine in the form of povidone-iodine is more effective than silver nitrate for decreasing the risk of pinkeye in newborns. However, it is not more effective than the medications erythromycin or chloramphenicol. Foot ulcers in diabetes . Applying iodine to foot ulcers might be beneficial (...) for people with foot ulcers related to diabetes. Inflammation of the uterus (endometritis) . Washing the vagina with a solution containing iodine in the form of povidone-iodine before a Cesarean delivery reduces the risk of the inflammation of the uterus. Painful fibrous breast tissue (fibrocystic breast disease) . Research shows that taking iodine, especially molecular iodine, reduces painful fibrous breast tissue. Breast pain (mastalgia) . Taking 3000-6000 mg of molecular iodine for 5 months seems

2009 National Centre for Complementary and Alternative Medicine

759. Antenatal care for uncomplicated pregnancies

. For women who book later in pregnancy the most clinically and cost-effective serum screening test (triple or quadruple test) should be offered between 15 weeks 0 days and 20 weeks 0 days. [2008] [2008] 1.7.2.4 When it is not possible to measure nuchal translucency, owing to fetal position or raised body mass index, women should be offered serum screening (triple or quadruple test) between 15 weeks 0 days and 20 weeks 0 days. [2008] [2008] 1.7.2.5 Information about screening for Down's syndrome should (...) resolved by the time the baby is born, only a woman whose placenta extends over the internal cervical os should be offered another transabdominal scan at 32 weeks. If the transabdominal scan is unclear, a transvaginal scan should be offered. [2008] [2008] 1.10 Fetal growth and well-being 1.10.1 Symphysis–fundal height should be measured and recorded at each antenatal appointment from 24 weeks. [2008] [2008] 1.10.2 Ultrasound estimation of fetal size for suspected large-for-gestational-age unborn babies

2008 National Institute for Health and Clinical Excellence - Clinical Guidelines

760. Postnatal care up to 8 weeks after birth

. This should include checking the baby's: appearance including colour, breathing, behaviour, activity and posture head (including fontanelles), face, nose, mouth including palate, ears, neck and general symmetry of head and facial features. Measure and plot head circumference eyes; check opacities and red reflex neck and clavicles, limbs, hands, feet and digits; assess proportions and symmetry heart; check position, heart rate, rhythm and sounds, murmurs and femoral pulse volume lungs; check effort, rate (...) and raised concern aised concern P Postpartum haemorrhage ostpartum haemorrhage 1.2.5 In the absence of abnormal vaginal loss, assessment of the uterus by abdominal palpation or measurement as a routine observation is unnecessary. [2006] [2006] 1.2.6 Assessment of vaginal loss and uterine involution and position should be undertaken in women with excessive or offensive vaginal loss, abdominal tenderness or fever. Any abnormalities in the size, tone and position of the uterus should be evaluated

2006 National Institute for Health and Clinical Excellence - Clinical Guidelines

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