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Fetal Foot Measurement

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661. Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Termination of Pregnancy Analgesia

of gemeprost pessaries (Cervidil®, Merck Serono SPA, Roma, Italy) in the posterior fornix of the vagina every 3 hours up to 5 doses. If the expulsion of the fetus did not occur, the therapeutic regimen was repeated after 24 hours from the initiation of the treatment. Induction-to-abortion time (hours) was considered the period of time comprised between the first gemeprost pessary administration and fetal expulsion. Failure of induction of abortion was defined as women undelivered after two completed cycles (...) ; Abortion, Fetus Procedure: Programmed Intermittent Epidural Bolus Procedure: Continuous Epidural Infusion Procedure: Procedure of interruption of pregnancy Drug: Drug used for analgesia procedures Device: Pump for programmed intermittent bolus. Device: Pump for continuous epidural infusion. Drug: Drug used for termination of pregnancy procedure. Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 104 participants

2013 Clinical Trials

662. Chiropractic Care and a Specific Regimen of Nutritional Supplementation for Patients With Acute Ankle Sprain: a Multisite Randomized Controlled Trial

nutritional supplement regimen to chiropractic care with a placebo nutritional supplement for patients with ankle sprains, in terms of speed and amount of improvement in physical function and pain. Our hypothesis is that chiropractic care plus nutritional supplements designed to supply necessary nutrients for ligament healing will have improved outcomes in pain and disability, compared to chiropractic care plus placebo. We will use the Foot and Ankle Ability Measure Activities of Daily Living Subscale (...) practice and suggested by Standard Process: 2 capsules 3 x day. Chronic phase (Weeks 5-16): Glucosamine Synergy. This supplement maintains connective tissue and joint health. The protocol is commonly used in chiropractic practice and suggested by Standard Process: 1 capsule 3 x day. Dietary Supplement: Dietary supplement Outcome Measures Go to Primary Outcome Measures : Foot and Ankle Ability Measure (FAAM) Activities of Daily Living Subscale (ADLS) [ Time Frame: baseline to 6 weeks ] Secondary Outcome

2013 Clinical Trials

663. Trial of Onset of Epidural Pain Relief With Low Dose Bupivacaine and Different Doses of Fentanyl in Laboring Women

, Actiq Outcome Measures Go to Primary Outcome Measures : The time, in minutes, since completion of epidural bolus to the first painless contraction [ Time Frame: Time since epidural bolus dose administration (At 1 and 5 minutes ) ] A painless contraction = verbal Numeric Pain Rating Scale less than or equal to 3/10 Secondary Outcome Measures : Sensory block height to ice [ Time Frame: 30 minutes after epidural bolus dose ] Pruritis [ Time Frame: 30 minutes after epidural bolus dose ] Pruritus (...) will be measured using a 4-point scale, where 0 is none, 1 is mild, 2 is moderate, and 3 is severe. Nausea [ Time Frame: 30 minutes after epidural bolus dose ] Nausea will be measured using a 4-point scale, where 0 is none, 1 is mild, 2 is moderate, and 3 is severe. Maternal sedation [ Time Frame: 30 minutes after epidural bolus dose ] Maternal sedation will be measured using a 5-point scale where 0 is wide awake, 1 is mildly drowsy, 2 is very drowsy, 3 is asleep but rousable, and 4 is somnolent. Hypotension

2013 Clinical Trials

664. Blue Light for Treating Psoriasis Vulgaris

intervention to prevent life-threatening illness or injury or permanent impairment to a body structure or a body function, c) led to foetal distress, foetal death or a congenital abnormality or birth defect. Other Outcome Measures: Hyperpigmentation of "Normal Skin Areas" Surrounding the Target Area Exposed to Blue Light and Control Area Not Exposed to Blue Light- Evaluation by Mexameter [ Time Frame: week 4, 12, 16 ] Arbitrary units measured by mexameter. Mexameter readings ranged from 0 to 100. Higher (...) Measures Go to Primary Outcome Measures : Change From Baseline (Visit 2) of the Local Psoriasis Area Severity Index (PASI) of the Target Area (High Intensity (HI) Group) as Compared to the Control Area at End of Treatment (Visit 7, Week 12). [ Time Frame: baseline and week 12 ] In this study only the "local" PASI (also called local psoriasis severity index - LPSI) was evaluated. The investigator evaluated and graded the severity of erythema, induration, and scaliness as the key symptoms of psoriasis

2013 Clinical Trials

665. Determination of the Minimum Local Analgesic Dose of Spinal Chloroprocaine in Labour

such as Bupivacaine, Levobupivacaine and Ropivacaine in CSE during labour have been published. But despite the reintroduction of Chloroprocaine recently there haven't been any investigations about spinal chloroprocaine. Chloroprocaine is already a long-know drug with a beneficial pharmacodynamic/kinetic profile. It is known for a very quick onset of action (2 - 3 minutes), high efficacy, rapid metabolism by plasma cholinesterases and short half-life both in mother and fetus. Because of this beneficial profile (...) the test dose of chloroprocaine with 2mg for the next patient in this study. Ineffective: the VAPS is more than 10mm after 15 minutes of monitoring. An ineffective result will increase the test dose of chloroprocaine with 2mg for the next patient in this study. Patients who indicate an ineffective result will receive a rescue treatment by the administration of 12ml levobupivacaine epidurally. Outcome Measures Go to Primary Outcome Measures : Intensity of sensory blockade during the next 15 minutes

2013 Clinical Trials

666. Increased nuchal translucency and short femur length as possible early signs of osteogenesis imperfecta type III Full Text available with Trip Pro

anthropometric parameters except for shortening of both femurs, but at 23 weeks an incorrect attitude of the feet was revealed. A clinical and radiographic diagnosis of OI type III was made only at birth, and through follow-up continuing to date.NT screening was successful for chromosomal abnormalities at 11-14 weeks of gestation. An increased NT thickness is also associated with numerous fetal anomalies and genetic syndromes in a chromosomally normal fetus. In our case there were no sonographic signs (...) Increased nuchal translucency and short femur length as possible early signs of osteogenesis imperfecta type III this paper reports an association between an increased Nuchal Translucency (NT) and Osteogenesis Imperfecta (OI), a type of skeletal dysplasia. Measurement of fetal NT at 10-14 weeks of gestation is a sensitive and effective screening method for chromosomal abnormalities.a 35-year- old Caucasian woman in her fourth pregnancy was referred to our clinic for an ultrasound scan at 12

2013 Journal of prenatal medicine

667. Occupational therapy for people with Parkinson's disease

and background 1 The process of developing the guidelines 3 iii)0 Introduction 3 iii)0 The aim of the guidelines and target audience 4 iii)0 Ratifi cation process 5 Background 7 iii)0 An overview of Parkinson’s 7 iii)0 Medical and surgical interventions 12 iii)0 Measuring disability and progression of the condition 14 iv)0 The impact of Parkinson’s on occupational performance 16 Part 2 The guidelines 19 1 Specifi c strategies for initiating and maintaining movement 21 1.10 Intrinsic cueing techniques 23 1.20 (...) , mental and emotional symptoms impacting on a specifi c physical, social and vocational environment means that a ‘one size fi ts all’ intervention with a single outcome measure is of limited, if any, value. Not surprisingly there has been little consensus, few randomised controlled trials, and therefore little evidence to synthesise. As stated in the Cochrane reviews, ‘there is inadequate evidence to evaluate the effect of occupational therapy for people with Parkinson’s disease’ but lack of evidence

2010 Publication 1554

668. Photobiomodulation Therapy Using the Realief Therapy System for the Treatment of Chemotherapy-associated Peripheral Neuropathy

includes assessment of geographic areas involved and the degree of neuropathy experienced. For the trial, each patient will be given 18 treatments of 30-minute duration, scheduled every three times weekly. The treatments will include laser exposure of any or all of 27 differentiated areas of the legs, feet, cervical spine region and lumbar spine region, for durations of 3 to 30 minutes, based on the symptom presentation at the time. Power densities will vary from 5 to 12 watts, based on the symptom (...) times weekly for 5-6 weeks. The treatments will include laser exposure of any or all of 27 differentiated areas of the legs, feet, cervical spine region and lumbar spine region, for durations of 3 to 30 minutes, based on the symptom presentation at the time. Power densities will vary from 5 to 12 watts, based on the symptom presentations through the course of therapy. Device: photobiomodulation The photobiomodulation delivered by Realief Therapy involves amplitude wavelength light delivered

2013 Clinical Trials

669. Patient Modesty: Volume 74

difficult to quantitatively score qualitative variables than to measure variables that lend themselves to quantification such as blood pressure, pulse rate, etc, but it’s done every day. I spent 20 years in the home of osteopathic medicine and had frequent interactions with students at what is now A. T. Still University. Students derisively referred to courses in which grades were not given as bedside-manner courses, dummy courses or dumbed-down courses. They did not take them seriously and considered

2016 Bioethics Discussion Blog

670. Low-grade inflammation and the brain

signal other immune cells and bring them to the site of infection. Inflammation is clinically assessed by measuring cytokine concentrations or other inflammatory markers in the blood and is used as a sign of infection. What is low-grade inflammation? It is a question that remains hard to answer. Low-grade inflammation is usually defined as “the chronic production, but a low-grade state, of inflammatory factors”. Conditions characterized by low-grade inflammation are for instance obesity (1 (...) -science based health industry. The public voting with its feet, perhaps unwisely. Some governments are supporting this industry by deregulating many in the health field at the same time as strengthening regulatory agencies for the actual science provider therapists, but hamstringing research dollars. A bad mix. The public cannot be blamed for attending less than reputable ‘health’ providers and anyone trying to get out the message that caution should be utilized, is effectively drowned out

2016 Body in Mind blog

671. Sickle Cell Anemia

circumstances, RBCs do not hemolyze Sickle Cell Anemia (S/S) Initially infant's RBCs mainly contain fetal Hb F Within months the abnormal Hb S replaces the Hb F Similar manifestations with one Hb S and one gene (or other bnormality) Sickle - One HgbS and one HgbB0 or HgbB+ V. Labs identifies opathies including Sickle Cell Trait and Sickle Cell Anemia Monitor liver function, and blood counts Frequently lower in Sickle Cell Anemia and may underestimate renal dysfunction See screening protocol below under (...) . Management: Hydroxyurea See for protocol Increases production of fetal (HbF) which does not sickle Often managed in conjunction with Sickle Cell Disease specialist Indications in adults 3 or more times in 12 months Severe or recurrent Severe symptomatic chronic affecting functional status Sickle cell associated pain significantly impacting function or quality of life Indications in children over age 9 months All children over age 9 months should be offered to reduce complications Contraindications

2015 FP Notebook

672. Umbilical Cord Prolapse

brim and presenting part IV. Risk factors Multiparity Prematurity Macrosomia Polyhydramnios High V. Signs Ill-fitting or non-engaged presenting part Prolapsed visualized in vagina or at vulva palpated on pelvic exam on May follow VI. Management: General Emergent only if imminent Deliver as if fetus has died Check for cord pulsations Check for fetal heart sounds to assess heart activity Pre-hospital cord prolapse noted at home by patient Patient assumes deep knee-chest position Emergent transport (...) to hospital VII. Management: Temporizing measures to relieve cord pressure Adjust maternal position to reduce cord pressure Raise foot of the bed (Trendelenburg's Position) Sims' position Mother in left lateral decubitus position Genu-pectoral position Mother in knee-chest position Vaginal retrograde pressure applied to presenting part Hand in vagina elevates presenting part Mother should stop pushing with 0.25 mg SC Consider filling with 500-700 cc Saline Minimize handling of the cord Do not attempt

2015 FP Notebook

673. Phase II Intratumoral IL12 Plasmid Electroporation in Cutaneous Lymphoma

, including laboratory results, deemed by the investigator to be likely to interfere with patient's participation in the study, or to interfere with the interpretation of the results; Participants with electronic pacemakers or defibrillators are excluded from this study as the effect of electroporation on these devices is unknown; Pregnant and breast-feeding women are excluded from the study as effects on the fetus are unknown and there may be a risk of increased fetal wastage. Contacts and Locations Go (...) in a circle were placed around the tumor. The applicator was connected to the OMS power supply and six pulseswere administered to each tumor lesion at the approximate point of tavo injection. Other Name: MedPulser Outcome Measures Go to Primary Outcome Measures : Objective Response Rate Assessed by Modified Severity Weighted Assessment Tool (mSWAT) Score in the Skin [ Time Frame: Every 28 days for the first 24-weeks of treatment ] ORR is defined as the percentage of participants that achieved a complete

2012 Clinical Trials

674. Single Arm Study With a Nitinol Self-Expanding Paclitaxel-Eluting Stent to Treat BTK Arteries

: Flanders Medical Research Program Information provided by (Responsible Party): Flanders Medical Research Program Study Details Study Description Go to Brief Summary: The objective of this clinical study is to evaluate the immediate and long-term (up to 12 month) safety and effectiveness of a Nitinol Self-Expanding Paclitaxel-Eluting stent for the treatment of patients with critical limb ischemia (i.e. rest pain or non-healing foot ulcers) due to the presence of arterial lesions in the below-the-knee (...) Name: Self-Expanding Paclitaxel-Eluting stent Outcome Measures Go to Primary Outcome Measures : Primary patency [ Time Frame: 6 months ] Primary patency rate at 6 months, defined by duplex ultrasound measurement of peak systolic velocity ratio ≤2.0 at the target lesion(s) with no clinically-driven reintervention within the treated segment, verified by Core Lab Primary patency [ Time Frame: 12 months ] Primary patency at 12 months, defined as absence of restenosis (≥50% stenosis) or occlusion within

2012 Clinical Trials

675. Imatinib and Carvedilol for High Blood Pressure in the Lungs in Adults With Sickle Cell Disease

related topics: related topics: available for: resources: Arms and Interventions Go to Outcome Measures Go to Primary Outcome Measures : An open-label non-controlled pilot study, to determine the safety and tolerability of 24-weeks of oral imatinib in SCD associated PAH and of oral carvedilol therapy in SCD associated PVH. Secondary Outcome Measures : Assess the efficacy and impact of imatinib and carvedilol on maximum exercise capacity as measured by peak oxygen consumption during a maximal CPET (...) or equal to 25 mmHg Suspicion of Pulmonary Hypertension based on any of the below criterion: - exertional breathlessness - echocardiographic evidence of tricuspid insufficiency (TRVgreater than or equal to 2.7 m/s) - oxy-hemoglobin desaturation during six minute walking test - hypoxia requiring supplemental oxygen - pedal edema - ascites - elevated BNP - or history of acute chest syndrome, stroke, or other serious complication of vaso-occlusive disease

2012 Clinical Trials

676. A FIVE-YEAR STUDY OF PREMATURITY Full Text available with Trip Pro

, leaving 12 with complications possibly ascribable to prematurity. Six of these had retrolental fibroplasia as a major handicap. In seven, mental retardation was the presenting problem. Most of the handicapped children had multiple handicaps, which included spasticity, delayed motor development, strabismus, etc. The incidence of the necessity for corrective measures for feet and legs appeared relatively high. In general, survivors compared favorably with the rest of the childhood population (...) A FIVE-YEAR STUDY OF PREMATURITY To get a comprehensive picture of prematurity and neonatal death or survival, all factors on the maternal and fetal records that might be pertinent were recorded. This information, having to do with factors such as age, gravida of the mother, blood group incompatibility, period of gestation, weight at birth, type of delivery, medication and anesthesia administered to the mother, is presented in tabular form. In the study of perinatal mortality it was noted

1956 California Medicine

677. The ontogenetic development of concentration differences for protein and ions between plasma and cerebrospinal fluid in rabbits and rats Full Text available with Trip Pro

the development of concentration differences for ions with the development of the blood-brain barrier to macromolecules we wanted to evaluate an eventual relationship between the development of these two functions of the blood-brain barrier.3. The concentration of protein in cerebrospinal fluid and plasma was measured in foetal, juvenile and adult rabbits and in new-born, juvenile and adult rats. The concentration of protein was similar in rabbit foetuses at 23 days of gestational age (term at 31 days (...) suggests that new-born rat produces little (if any) cerebrospinal fluid suggesting that the high concentration of protein in cerebrospinal fluid in new-born rats reflect a low rate of turnover of cerebrospinal fluid.5. The concentration of sodium, potassium, chloride and magnesium in plasma and cisternal cerebrospinal fluid was measured in rabbits of different age, from 23 days of gestation until adulthood, and in rats of different ages from birth until adulthood.6. Concentration differences between

1974 The Journal of physiology

678. Management of Pregnancy

or ancillary testing and imaging studies. To date, no single test or sequence of tests has an optimal sensitivity or predictive value for preterm birth. Fetal fibronectin testing and cervical length measurement by transvaginal ultrasound appear to be useful in the management of some women meeting the criteria for increased surveillance. Most studies have shown that these tests have limited utility when used in the asymptomatic woman at low risk for preterm delivery. Importantly, VA/DoD Clinical Practice (...) Weeks) 51 I- 22. Establishing the Gestational Age: Weeks 10-12 51 I- 23. Auscultation Fetal Heart Tones: Weeks 10-12, All following visits 53 I- 24. Screening Fundal Height: Weeks 10-12; All following visits 54 I- 25. Assessing (Inappropriate) Weight Gain: Weeks 10-12; All following visits 55 I- 26. Nutritional Supplements: Weeks 10-12 56 I- 27. Obesity: Weeks 10-12 58 I- 28. History of Gastric Bypass/Bariatric Surgery: Weeks 10-12 59 I- 29. Screening for Gonorrhea: Weeks 10-12 60 I- 30. Screening

2009 VA/DoD Clinical Practice Guidelines

679. Patient Modesty: Volume 71

... First let me apologize for not having a correct link in Vol 70, so here is the synopsis of the study on Forwomenseyesonly: Next I will do this post in 2 parts. I was originally posting this on Vol 70 when it closed... Maurice, Ed T, Ray, t al , I agree that this is great. All along I have been demonstrating [call it if you will] a "review of literature" research style proving this exact point. I started out with my post . When you take all intent out of the equation, and measure the only thing (...) that can be measures and validated, the actions, you see that they are almost identical. So why would one be emotionally traumatic and the other not? Remember this post: ? To really illustrate my point I devised a test (half way down the page in blue) on my posts: " " and " ." Yes, I am over the top, possibly inflammatory, and probably offensive. A friend told me just yesterday that I am as subtle as a drag queen. I know this, but look at the denial that I am dealing with. I do warn my readers that my

2015 Bioethics Discussion Blog

680. British Association of Dermatologists' guidelines for biologic interventions for psoriasis

or not a patient should be considered for biologic therapy, clinicians should take into account the applicability of these measures to each individual patient. There are circumstances where the use of these tools fails to give a suf?ciently accurate assessment of the clinical situation. With respect to the PASI, this is espe- cially pertinent in patients with localized disease that involves special ‘high-impact’ sites (genitalia, hands, feet, head and neck) where highly signi?cant functional (...) therapy and conse- quent, predictable risks of toxicity. At present, the risks and bene?ts of biologic therapies relative to standard systemic ther- apy are largely unknown. Widespread use of these agents in uncomplicated moderate to severe psoriasis is inappropriate and is not supported by the licensed indications for these drugs. Eligibility criteria should encompass both objective measures of disease severity and the impact the disease has on quality of life. All existing disease severity

2009 British Association of Dermatologists

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