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Fetal Abdominal Circumference

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701. Optimal risk-assessment of small-for-gestational-age using 31-34 weeks biometry in a low-risk population. (Abstract)

. Fetal malformations, Doppler anomalies and preterm delivery before 37 weeks were excluded. SGA was defined by various percentile cut-offs of birth weight. The probability of SGA was modeled as a function of Z-scores of femur length, abdominal circumference and head circumference. The model was validated on a second independent dataset of 1725 pregnancies from a different screening unit. The screening performance of this probabilistic approach was compared with those of traditional EFW growth charts (...) Optimal risk-assessment of small-for-gestational-age using 31-34 weeks biometry in a low-risk population. To compare the performance of traditional growth charts for estimated fetal weight (EFW) and a validated pragmatic probabilistic approach using biometry at 31-34 weeks' gestation to screen for late pregnancy small-for-gestational age (SGA) fetuses in a low-risk population.Records of ultrasound biometry at 31-34 weeks were reviewed in 7755 consecutive low-risk women between 2002 and 2011

2013 Ultrasound in Obstetrics and Gynecology

702. The long-term impact of intrauterine growth restriction in a diverse U.S. cohort of children: The EPOCH study. Full Text available with Trip Pro

= 0.003) in adolescence, independent of other childhood and maternal factors.Our data from a contemporary US cohort suggests that children exposed to IUGR have increased abdominal fat and increased insulin resistance biomarkers despite no differences in BMI growth patterns beyond 12 months of age. These data provide further support for the fetal programming hypothesis.Copyright © 2013 The Obesity Society. (...) The long-term impact of intrauterine growth restriction in a diverse U.S. cohort of children: The EPOCH study. To explore the long-term impact of intrauterine growth restriction (IUGR) among a diverse, contemporary cohort of U.S. children.A retrospective cohort of 42 children exposed to IUGR and 464 unexposed who were members of Kaiser Permanente of Colorado. Height and weight measurements since birth and measures of abdominal adiposity and insulin-resistance were measured at an average age

2013 Obesity

703. Second-trimester discordance and adverse perinatal outcome in twins: the STORK multiple pregnancy cohort. (Abstract)

hospitals over a period of 10 years. Methods Logistic regression and receiver operating characteristic (ROC) curve analyses were performed to evaluate the association between abdominal circumference (AC) and estimated fetal weight (EFW) discordance, recorded between 20 and 22 weeks of gestation, and adverse pregnancy outcomes.Stillbirth, neonatal mortality, preterm birth (PTB) at <34 weeks of gestation, and birthweight (BW) discordance ≥25%.A total of 2399 twin pregnancies [457 monochorionic (MC (...) ) and 1942 dichorionic (DC)] were included in the study. The predictive accuracy of the EFW discordance was poor for fetal loss after 22 weeks of gestation (area under the curve, AUC 0.54, 95% CI 0.46-0.64), fetal loss beyond 28 weeks of gestation (AUC 0.42, 95% CI 0.31-0.52), perinatal loss (AUC 0.51, 95% CI 0.44-0.57), BW discordance (AUC 0.63, 95% CI 0.56-0.65), and PTB before 34 weeks of gestation (AUC 0.52, 95% CI 0.49-0.55). There was no significant difference in the prediction of these outcomes

2013 BJOG

704. Intrauterine Growth Retardation

and comorbid factors abuse (most significant individual risk) Poor Nutrition Use Minimal to no tic stress Follow s (kick) counts Follow Serial s for growth IV. Diagnosis Detection rate in-utero: 70% Indications for Low risk fetus smaller than expected size High risk monitoring interpretation to Abdominal Circumference ratio Most useful in assessing V. Management Address risk factors Eliminate other negative habits Ensure adequate maternal weight gain Maximize Reduce environmental stressors Perinatology (...) Indications Poor Decreasing Biparietal diameter Oligohydramnios Abdominal circumference 4 weeks less than BPD Early Delivery Indications Doppler diastolic flow 0 mmHg in umbilical artery VI. Complications: Peripartum Risks of IUGR Intrauterine Asphyxia Polycythemia VII. Causes: Intrauterine Growth Retardation (IUGR) (Head and body growth retarded) (head growth spared) VIII. References Gabbe (1996) Obstetrics, Churchill, p. 863-886 Images: Related links to external sites (from Bing) These images

2015 FP Notebook

705. A systematic review of benzene exposure during pregnancy and adverse outcomes on intrauterine development and birth: still far from scientific evidence. (Abstract)

with maternal exposure to benzene or early exposure to aromatic solvents, while the evaluation of the relationship between benzene exposure during pregnancy and other parameters (i.e., birthweight, fetal weight, birth length, head circumference growth, fetal femur length, and abdominal circumference) returned no clear conclusions.Further studies are required to confirm and clarify the possible adverse outcomes of benzene exposure during pregnancy. Recommendations for future studies are related to the most (...) A systematic review of benzene exposure during pregnancy and adverse outcomes on intrauterine development and birth: still far from scientific evidence. The effect of exposure to some air pollutants during pregnancy on embryonic and fetal development has been evaluated by several studies, but it has not been well defined. The main objective of this study was to use a systematic review to evaluate the relationship between air benzene exposure in pregnant women and possible negative effects

2012 Annali di igiene : medicina preventiva e di comunità

706. Individualized Fortification of Breast Milk

thickness [ Time Frame: from inclusion at postmentrual age <32 weeks until 18 month corrected age ] change in skin fold thickness [cm] feeding intolerance [ Time Frame: during intervention (postmentrual age <32 weeks until 36 weeks) ] occurence of feeding intolerance defined by vomitting, bloody gastric residuals, or abnormal abdomen (tender, discolored, absent bowel sounds) morbidity [ Time Frame: during intervention (postmentrual age <32 weeks until 36 weeks) ] nutrient's blood parameter [ Time Frame (...) of these infants will be compared with that of infants fed mother's milk that has been supplemented with the current standard amounts. The postnatal growth of the infants will be assessed by measuring weight, length and head circumference and fat and lean mass using highly accurate, non-invasive methods throughout the intervention period and at the first follow-up visit after discharge at 3 months. Neurological development will be analyzed at the age of 18 months. The investigators hypothesize

2012 Clinical Trials

707. The breadth of the placental surface but not the length is associated with body size at birth. (Abstract)

of the head, chest, abdomen and thigh with increasing placental breadth. In contrast no measurement of baby's body size was related to placental length. Birth weight increased by 125 g per cm increase in placental breadth (95% confidence interval 88 to 162, p < 0.001) but only by 20 g per cm increase in placental length (-13 to 53, p = 0.2). The corresponding figures for head circumference were 0.28 cm (0.17-0.39, p < 0.001) and 0.03 (-0.07 to 0.14, p = 0.5). The associations between placental breadth (...) The breadth of the placental surface but not the length is associated with body size at birth. Studies of pregnancies complicated by preeclampsia led to the suggestion that the surface of the placenta is aligned along two axes, measured by its breadth and length. It was hypothesised that tissue along the breadth serves as a nutrient sensor, responding to the mother's nutritional state and fetal nutritional demands, while tissue along the length has different functions. To develop

2012 Placenta

708. Quality of ultrasound biometry obtained by local health workers in a refugee camp on the Thai-Burmese Border. Full Text available with Trip Pro

prospective observational study included 1090 women who had a dating crown-rump length (CRL) scan and one study-appointed ultrasound biometry scan between 16 and 40 weeks of gestation. The average of two measurements of each of biparietal diameter, head circumference, abdominal circumference and femur length was used in a polynomial regression model for the mean and SD against gestational age (GA). The biometry equations obtained were compared with published equations of professional sonographers from (...) Quality of ultrasound biometry obtained by local health workers in a refugee camp on the Thai-Burmese Border. In a refugee camp on the Thai-Burmese border, accurate dating of pregnancy relies on ultrasound measurements obtained by locally trained health workers. The aim of this study was to substantiate the accuracy of fetal biometry measurements performed by locally trained health workers by comparing derived reference equations with those published for Asian and European hospitals.This

2012 Ultrasound in Obstetrics and Gynecology

709. Two-Dimensional sonographic placental measurements in the prediction of small for gestational age infants. (Abstract)

in SGA pregnancies, the lag in abdominal circumference (AC) being the most predictive of SGA (P<0.0001). Multivariable models were significantly predictive of both SGA<10(th) percentile (area under the receiver-operating characteristics curve (AUC) =0.7404) and <5(th) percentile (AUC=0.7204), the best fitting models including AC lag and mean placental diameter and thickness.2D placental measurements taken in mid-gestation are significantly associated with the incidence of SGA. Biometric lags can (...) Two-Dimensional sonographic placental measurements in the prediction of small for gestational age infants. To determine the utility of two-dimensional (2D) sonographic placental measurements in the prediction of small-for-gestational-age (SGA) infants.The maximal diameter along the fetal surface of the placenta and the maximal placental thickness were measured at 18-24 weeks' gestation, and the measurements repeated in the orthogonal plane. 'Biometric lags' were calculated as the difference

2012 Ultrasound in Obstetrics and Gynecology

710. The hematologic profile of neonates with growth restriction is associated with the rate and degree of prenatal Doppler progression. Full Text available with Trip Pro

The hematologic profile of neonates with growth restriction is associated with the rate and degree of prenatal Doppler progression. To examine the relationship between hematologic parameters at birth and prenatal progression of Doppler abnormalities in fetal growth restriction (FGR).The study was a secondary analysis of FGR patients (abdominal circumference < 5th percentile and umbilical artery pulsatility index (UA-PI) elevation) with at least three examinations prior to delivery. Prenatal

2012 Ultrasound in Obstetrics and Gynecology

711. Effects of antenatal recognition and follow-up on perinatal outcomes in small-for-gestational age infants delivered after 36 weeks. Full Text available with Trip Pro

(birthweight <3rd percentile) were more frequently diagnosed antenatally (30%). Admission to NICU (14 vs. 3%, p < 0.001) and cesarean delivery (42 vs. 26%; p < 0.001) were more likely in group A. Adverse outcomes related to hypoxia were all observed in group B, but the difference was not significant. In antenatally detected fetuses a combination of fetal abdominal circumference, umbilical artery pulsatility index and middle cerebral artery pulsatility index z-scores was useful for prediction of NICU

2012 Acta Obstetricia et Gynecologica Scandinavica

712. Ultrasound scans in obese pregnant women: Feasibility, quality and factors in its improvement. (Abstract)

for all images except abdominal circumference (P = 0.26) and spine (P = 0.06). Anatomical quality scores were also significantly lower in the obese group (22.3 vs. 27.2; P = 0.001).Although ultrasound scans of obese pregnant women are feasible, image quality and global anatomical scores are significantly lower among obese than normal-weight women. However, certain simple improvements may increase fetal visualization.Copyright © 2013 ISUOG. Published by John Wiley & Sons, Ltd. (...) outflow tract images. Significant factors associated with completing the scan in the multivariate model were: having 10 additional minutes for the scan (P = 0.03), moving the fetus so that the back was in posterior or lateral position (P = 0.01), more experienced sonographer (P = 0.03) and thinner maternal abdominal wall thickness (P = 0.01). Overall, the excellence rate varied from 35% to 92% in the normal BMI group and from 18% to 58% in the obese group, and was significantly lower in the latter

2012 Ultrasound in Obstetrics and Gynecology

713. Newborn Size and Body Composition as Predictors of Insulin Resistance and Diabetes in the Parents: Parthenon Birth Cohort Study, Mysore, India. Full Text available with Trip Pro

(head, abdomen, and mid-upper-arm circumference [MUAC]). Nine and a half years later, glucose tolerance and fasting insulin were measured in their parents (469 mothers and 398 fathers).Sixty-two (15.6%) fathers and 22 (4.7%) mothers had developed diabetes. There were linear inverse associations of the children's birth weight, CHL, CRL, MUAC, and skinfolds with paternal diabetes and insulin resistance (P < 0.05 for all). Offspring birth weight and adiposity (MUAC, abdominal circumference (...) Newborn Size and Body Composition as Predictors of Insulin Resistance and Diabetes in the Parents: Parthenon Birth Cohort Study, Mysore, India. We aimed to examine detailed neonatal measurements as predictors of later diabetes in both parents.Babies (n = 617) born to nondiabetic parents in Holdsworth Memorial Hospital, Mysore, India, were measured at birth for weight; crown-to-heel length (CHL), crown-to-rump length (CRL), and leg length; skinfolds (triceps and subscapular); and circumferences

2012 Diabetes Care

714. Correlation of Cord Blood Lipid Heterogeneity in Neonates with Their Anthropometry at Birth Full Text available with Trip Pro

Correlation of Cord Blood Lipid Heterogeneity in Neonates with Their Anthropometry at Birth Fetus with intrauterine stress may exhibit programmed changes that can alter its metabolism and bear severe risk for diseases in adult life. The current study was designed to assess the correlation between cord blood lipid profile with the anthropometric data in neonates.146 newborn babies born at Dr. T M A Pai Hospital, Udupi were screened and their birth weight, length, head circumference and abdominal (...) circumference were noted at birth. Umbilical cord blood samples were analyzed for total cholesterol, triglycerides (TG), high density lipoprotein (HDL) and low density lipoprotein (LDL). Infants were also grouped further based on gestational age (GA) and sex-adjusted birth weight percentiles into three groups i.e. Small for gestational age (SGA), Appropriate for gestational age (AGA) and Large for gestational age (LGA) for comparison of their lipid profiles. Inclusion criteria were normal fetal heart rate

2012 Indian Journal of Clinical Biochemistry

715. Thymic volume in healthy, small for gestational age and growth restricted fetuses. (Abstract)

Thymic volume in healthy, small for gestational age and growth restricted fetuses. The aim of this study was to verify the hypothesis that a difference in thymic size exists between small for gestational age (SGA) fetuses, likely constitutional, and intrauterine growth restricted (IUGR) fetuses because of placental causes.We studied 27 SGA and 36 control fetuses. SGA was defined as fetal abdominal circumference (AC) and birthweight <10th percentile for gestational age. We defined (...) as constitutional SGA those with normal uterine and umbilical artery Doppler flow velocity waveforms (FVW), and as IUGR those with abnormal uterine FVW. IUGR were further divided based on normal or abnormal umbilical FVW. Fetal thymic volume (TV) was acquired by three-dimensional ultrasound and reconstructed with virtual organ computer-aided analysis. To correct for the influence of fetal size on thymic dimension, TV/AC ratio was calculated.Controls presented a higher TV/AC compared with each group of SGA (p

2012 Prenatal diagnosis

716. Maternal Antiviral Prophylaxis to Prevent Perinatal Transmission of Hepatitis B Virus in Thailand

Weight, height and head circumference for age [ Time Frame: at 6 months and 12 months of age ] Weight, length/height and head circumference WHO Z scores Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below (...) anti-HBV treatment during the current pregnancy Creatinine clearance <50 ml/min, calculated using the Cockcroft-Gault formula Dipstick proteinuria>1+ (>30 mg/dL) or normoglycemic glucosuria confirmed on two separate occasions Positive serology for Hepatitis C infection less than 12 months prior to enrollment Evidence of pre-existing fetal anomalies incompatible with life Any concomitant condition or treatment that, in the view of the clinical site investigator, would contraindicate participation

2012 Clinical Trials

717. Growth of Infants Fed an Elemental Medical Food

: Experimental Study Formula feed as lib Other Names: free-amino acid-based medical food EleCare Outcome Measures Go to Primary Outcome Measures : Weight [ Time Frame: 14 days of age to 112 days of age ] weight gain during the study period Secondary Outcome Measures : Anthropometric Measurements [ Time Frame: 14 days of age to 112 days of age ] length, head circumference, and length gain GI Tolerance [ Time Frame: At visits 14 and 28 ] daily stool number, stool consistency, formula intake Lab Measurement (...) (Child) Sexes Eligible for Study: All Accepts Healthy Volunteers: Yes Criteria Inclusion Criteria: Singleton, healthy infant Gestational age of 37 to 42 weeks Birth weight of 2500 grams or greater Age between birth and 9 days of age Parents agree to not administer mineral or vitamin supplements during the study period Parents agree to feed study formula exclusively for the duration of the study Exclusion Criteria: Maternal, fetal or perinatal history which may have adverse effects on growth Multiple

2012 Clinical Trials

718. Lifestyle Intervention Forever: Healthy Weight for Pregnancy and Birth (Pilot Study)

[ Time Frame: 10-25 weeks ] Fetal growth and abdominal circumference will be examined by fetal ultrasound at approximately 28-30, 34-36 and 38-40 weeks gestation and/or as part of routine care after 28 weeks gestation. Measure Neonatal size at birth [ Time Frame: Within 48 hours of birth ] Between group comparisons of birth size will include birth weight (g), crown-heel length (mm), head circumference (mm), body mass index (kg/m2), ponderal index. Population-specific standard deviation (SD) scores (...) /metabolic profiles (fasted blood sample); obstetric parameters (incidence of GDM, preeclampsia, cesarean deliveries, obstetric trauma and neonatal complications) Offspring Outcomes: fetal growth pattern (fetal ultrasound); neonatal anthropometry assessed ≤ 48 h of birth (crown-heel length, weight, head, chest and waist circumferences, skinfold analyses); metabolic markers at birth (cord blood); and infant anthropometry at 12 weeks of age (as above). The experimental hypotheses to be tested

2012 Clinical Trials

719. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for Growth Hormone Use in Growth Hormone-deficient Adults and Transition Patients

in Endocrine Practice (Tables 1 and 2) (21 [EL 4]). Table 1 Levels of scientific substantiation in evidence-based medicine a Level Description Comments 1 Prospective, randomized, controlled trials—large Data are derived from a substantial number of trials, with adequate statistical power involving a substantial number of outcome data subjects Large meta-analyses using raw or pooled data or incorporating quality ratings Well-controlled trial at one or more centers Consistent pattern of findings (...) patients (Grade A; BEL 1). 5.4 Recommendations and evidence base for monitoring the efficacy of GH r eplacement in adults with GHD • R25. When maintenance doses are achieved, serum IGF-I, fasting glucose levels, hemoglobin A1c, BMI, waist circumference, waist-to-hip ratio, serum-free T 4 , and assessment of the hypothalamic-pituitary-adrenal axis clinically or via early morning cortisol or cosyn- tropin stimulation test (in patients not on glucocorti- coid replacement), testosterone and fasting lipid

2009 American Association of Clinical Endocrinologists

720. Management of Pregnancy

Weeks) 51 I- 22. Establishing the Gestational Age: Weeks 10-12 51 I- 23. Auscultation Fetal Heart Tones: Weeks 10-12, All following visits 53 I- 24. Screening Fundal Height: Weeks 10-12; All following visits 54 I- 25. Assessing (Inappropriate) Weight Gain: Weeks 10-12; All following visits 55 I- 26. Nutritional Supplements: Weeks 10-12 56 I- 27. Obesity: Weeks 10-12 58 I- 28. History of Gastric Bypass/Bariatric Surgery: Weeks 10-12 59 I- 29. Screening for Gonorrhea: Weeks 10-12 60 I- 30. Screening (...) Provider Referral/Consult with Advanced Prenatal Care Provider Consider Referral/Consult with Advanced Prenatal Care Provider GENERAL CONDITIONS Genetic condition potentially affecting fetus v Body Mass Index (BMI 30) v Age 34 v Genetic condition affecting patient or spouse v OBSTETRIC CONDITIONS (current or historical) Recurrent pregnancy loss v Ectopic pregnancy v Significant abdominal pain/cramping v Vaginal bleeding v Second-trimester pregnancy loss v Preterm labor (current) or birth (history) v

2009 VA/DoD Clinical Practice Guidelines

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