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Fetal Abdominal Circumference

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201. Antiphospholipid Antibodies and Fetal Growth Restriction

-Probability Sample Study Population Pregnant patients admitted for fetal growth restriction (cases) and normal patients in labor at term (controls). Criteria Inclusion Criteria: Gestational age between 24-34 weeks. Ultrasonographic evidence of fetal growth restriction Abdominal circumference < 3rd percentile. Doppler with increase of placental resistance. Exclusion Criteria: Known antiphospholipid syndrome. Known presence of antiphospholipid antibodies. Patients with systemic lupus erythematosus. Contacts (...) Antiphospholipid Antibodies and Fetal Growth Restriction Antiphospholipid Antibodies and Fetal Growth Restriction - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Antiphospholipid Antibodies and Fetal Growth

2012 Clinical Trials

202. Systematic review of methodology used in ultrasound studies aimed at creating charts of fetal size. Full Text available with Trip Pro

of retrieved articles.Observational studies whose primary aim was to create ultrasound size charts for bi-parietal diameter, head circumference, abdominal circumference and femur length in fetuses from singleton pregnancies.Studies were scored against a predefined set of independently agreed methodological criteria and an overall quality score was given to each study. Multiple regression analysis between quality scores and study characteristics was performed.Eighty-three studies met the inclusion criteria (...) Systematic review of methodology used in ultrasound studies aimed at creating charts of fetal size. Reliable ultrasound charts are necessary for the prenatal assessment of fetal size, yet there is a wide variation of methodologies for the creation of such charts.To evaluate the methodological quality of studies of fetal biometry using a set of predefined quality criteria of study design, statistical analysis and reporting methods.Electronic searches in MEDLINE, EMBASE and CINAHL, and references

2012 BJOG

203. Accuracy of imaging parameters in the prediction of lethal pulmonary hypoplasia secondary to mid-trimester prelabor rupture of fetal membranes: a systematic review and meta-analysis. Full Text available with Trip Pro

studies that reported on the prediction of lethal pulmonary hypoplasia. The quality of the included studies was poor to mediocre. The estimated sROC curves for the chest circumference/abdominal circumference ratio and other parameters showed limited accuracy in the prediction of pulmonary hypoplasia. In women with mid-trimester PPROM, the available evidence indicates limited accuracy of biometric parameters in the prediction of pulmonary hypoplasia.Copyright © 2012 ISUOG. Published by John Wiley (...) Accuracy of imaging parameters in the prediction of lethal pulmonary hypoplasia secondary to mid-trimester prelabor rupture of fetal membranes: a systematic review and meta-analysis. In women who have suffered mid-trimester prelabor rupture of membranes (PPROM), prediction of pulmonary hypoplasia is important for optimal management. We performed a systematic review to assess the capacity of imaging parameters to predict pulmonary hypoplasia. We searched for published articles that reported

2012 Ultrasound in Obstetrics and Gynecology

204. Sonographic prediction of fetal macrosomia: the effect of sonographic fetal weight estimation model and threshold used. Full Text available with Trip Pro

Sonographic prediction of fetal macrosomia: the effect of sonographic fetal weight estimation model and threshold used. To compare the accuracy of 21 sonographic fetal weight-estimation models and abdominal circumference (AC) as a single measure for the prediction of fetal macrosomia (> 4000 g) using either fixed or optimal model-specific thresholds.A total of 4765 sonographic weight estimations performed within 3 days prior to delivery were analyzed. The predictive accuracy of 21 published (...) sonographic fetal weight-estimation models was calculated using three different thresholds: a fixed threshold of 4000 g; a model-specific threshold obtained from the inflexion point of the receiver-operating characteristics (ROC) curve; and a model-specific threshold associated with the highest overall accuracy. Cluster analysis was used to determine whether a certain combination of fetal biometric indices is associated with a higher predictive accuracy than others.For a fixed threshold of > 4000 g

2011 Ultrasound in Obstetrics and Gynecology

205. Ultrasound prediction of birthweight and growth restriction in fetal gastroschisis (Abstract)

Ultrasound prediction of birthweight and growth restriction in fetal gastroschisis Most ultrasound estimated fetal weight (EFW) formulas incorporate abdominal circumference, which may overstimate growth restriction in fetal gastroschisis. The aim of this study was to determine the optimal ultrasound formula for prediction of birthweight and fetal growth restriction (FGR) in gastroschisis.We conducted a retrospective cohort analysis of singleton fetuses with gastroschisis. Percentage of error

2010 EvidenceUpdates

206. Prediction of intrauterine fetal death (IUFD) associated with small for gestational age: impact of including ultrasound biometry in the customized models. Full Text available with Trip Pro

multiple regression (Cust-chart). The same process was repeated including second-trimester biometric parameters: biparietal diameter, head circumference, femur length and abdominal circumference in the regression models (Cust-plus-USS-chart). The association between small-for-gestational age < 10(th) centile (SGA) pregnancies, defined using the two customized charts or our population-based growth chart (Pop-chart) and IUFD, were compared. Statistical analyses including OR, 95% CI and screening accuracy (...) Prediction of intrauterine fetal death (IUFD) associated with small for gestational age: impact of including ultrasound biometry in the customized models. Customized growth charts derived from maternal demographic characteristics alone have been shown to improve the prediction of pregnancy complications compared to population growth curves. We sought to estimate the impact of adding ultrasound biometric parameters to the customized chart for the prediction of intrauterine fetal death (IUFD

2011 Ultrasound in Obstetrics and Gynecology

207. The duration of persistent abnormal ductus venosus flow and its impact on perinatal outcome in fetal growth restriction. Full Text available with Trip Pro

The duration of persistent abnormal ductus venosus flow and its impact on perinatal outcome in fetal growth restriction. To study if the duration of individual Doppler abnormalities is an independent predictor of adverse outcome in fetal growth restriction (FGR) caused by placental dysfunction.This was a secondary analysis of patients with FGR (abdominal circumference < 5(th) percentile and umbilical artery (UA) pulsatility index (PI) elevation) who had at least three examinations before

2011 Ultrasound in Obstetrics and Gynecology

208. Influence of fetal and parental factors on intra-uterine growth measurements: results of the EDEN mother-child cohort. Full Text available with Trip Pro

cohort included 2002 pregnant women with singleton pregnancies attending one of two university hospitals. Data from two routine ultrasound examinations for fetal biometry were recorded, at 20-25 and 30-35 weeks of gestation. Biparietal diameter (BPD), head circumference (HC), femur length (FL), abdominal circumference (AC) and estimated fetal weight (EFW) were studied as a function of prepregnancy maternal body mass index (BMI), maternal height, paternal height, fetal sex and gestational age.Data (...) Influence of fetal and parental factors on intra-uterine growth measurements: results of the EDEN mother-child cohort. In small-for-gestational-age neonates, parental and fetal characteristics can be used to distinguish between constitutionally small size and growth restriction, which is associated with a higher risk of morbidity and mortality. The aim of this study was to quantify relationships of parental and fetal characteristics with fetal ultrasound measurements.The EDEN mother-child

2011 Ultrasound in Obstetrics and Gynecology

209. Effect of L-arginine on the expression of Bcl-2 and Bax in the placenta of fetal growth restriction. (Abstract)

intervals. The newborn birth weight and perinatal outcomes were also documented. Placental tissue was sampled within 10 min after delivery for analysis. The expression of Bcl-2 and Bax in placental tissue was determined by immunohistochemical technique.The fetal growth parameters of biparietal diameter, femur length, and abdominal circumference increased more significantly in L-arginine group than those in control group (p < 0.01). The cure rate and birth weight in L-arginine group were higher than (...) Effect of L-arginine on the expression of Bcl-2 and Bax in the placenta of fetal growth restriction. To investigate the effect of l-arginine on fetal growth restriction (FGR) in terms of the expression of Bcl-2 and Bax in placenta.Sixty pregnant women with FGR were randomized to receive conventional treatment alone (control group, n = 30) or in combination with L-arginine (L-arginine group, n = 30). The parameters of fetal growth and development were monitored by B-ultrasound at regular

2011 The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Controlled trial quality: uncertain

210. The use of three-dimensional ultrasound does not improve training in fetal biometric measurements. (Abstract)

circumference (HC), abdominal circumference (AC), and femur length (FL)) by a trainer. Subsequently, each midwife measured the parameters on another 10 fetuses. The same set of measurements was repeated by the trainer. The percentage deviation between the midwives' and the trainer's measurements was determined and compared between training groups. Time required for completion was recorded. Frozen images were reviewed by another sonographer to assess the image quality using a standardized scoring system.The (...) The use of three-dimensional ultrasound does not improve training in fetal biometric measurements. To investigate whether three-dimensional (3D) technology offers any advantage over two-dimensional (2D) ultrasound in fetal biometric measurement training.Ten midwives with no hands-on experience in ultrasound were randomized to receive training on 2D or 3D ultrasound fetal biometry assessment. Midwives were taught how to obtain fetal biometric measurements (biparietal diameter (BPD), head

2011 The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Controlled trial quality: uncertain

211. Biometry and estimated fetal weight by two-dimensional and three-dimensional ultrasonography: an intra- and inter-observer reliability and agreement study. Full Text available with Trip Pro

Biometry and estimated fetal weight by two-dimensional and three-dimensional ultrasonography: an intra- and inter-observer reliability and agreement study. To evaluate and compare the intraobserver and interobserver reliability and agreement for the biparietal diameter (BPD), abdominal circumference (AC), femur length (FL) and estimated fetal weight (EFW) obtained by two-dimensional ultrasound (2D-US) and three-dimensional ultrasound (3D-US).Singleton pregnant women between 24 and 40 weeks were (...) that the SD values determined from 3D-US differences were smaller than those obtained for 2D-US. Higher proportions of differences were below the arbitrarily defined cut-off points when using 3D-US.3D-US improved the reliability and agreement of fetal measurements and EFW compared with 2D-US.Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.

2011 Ultrasound in Obstetrics and Gynecology

212. Fetal omphalocele ratios predict outcomes in prenatally diagnosed omphalocele. (Abstract)

repair. Omphalocele diameter upon antenatal ultrasound was compared with abdominal circumference, femur length, and head circumference, yielding the respective omphalocele (O)/abdominal circumference (AC), O/femur length (FL), and O/head circumference (HC) ratios. The absolute measurements were used to classify giant lesions. Omphalocele ratios and giant omphalocele designations were evaluated as predictors of inability to achieve primary repair.Among 25 included cases, staged or delayed closure (...) Fetal omphalocele ratios predict outcomes in prenatally diagnosed omphalocele. The objective of the study was to evaluate whether ratios considering omphalocele diameter relative to fetal biometric measurements perform better than giant omphalocele designation at predicting inability to achieve neonatal primary surgical closure.Cases of fetal omphalocele that underwent evaluation between May 2003 and July 2010 were identified. Inclusion was restricted to live births with plan for postnatal

2011 American Journal of Obstetrics and Gynecology

213. Standardization of fetal ultrasound biometry measurements: improving the quality and consistency of measurements. Full Text available with Trip Pro

signed ranks test, and variance was assessed using Pitman's test. Interobserver agreement was also assessed using the intraclass correlation coefficient (ICC), and all images were scored for quality in a blinded fashion.At baseline the level of agreement and image scoring were high. A significant reduction in the differences between sonographers and the lead sonographer were seen for fetal biometry overall (head circumference, abdominal circumference and femur length) between the first and third (...) Standardization of fetal ultrasound biometry measurements: improving the quality and consistency of measurements. To assess whether a standardization exercise prior to commencing a fetal growth study involving multiple sonographers can reduce interobserver variation.In preparation for an international study assessing fetal growth, nine experienced sonographers from eight countries participated in a standardization exercise consisting of theoretical and practical sessions. Each performed a set

2011 Ultrasound in Obstetrics and Gynecology

214. What are the limits of accuracy in fetal weight estimation with conventional biometry in 2D ultrasound? A novel postpartum study. Full Text available with Trip Pro

biometric parameters.This was a prospective multicenter study including 628 singleton pregnancies at term. Inclusion criteria were healthy newborns with no physical or chromosomal malformations. Postpartum measurement of head circumference, abdominal circumference and thigh length was performed. Six 'best-fit' formulae were derived using forward regression analysis in a formula-finding group (n = 419), and their accuracy was compared with birth weight in an evaluation group (n = 209) using percentage (...) What are the limits of accuracy in fetal weight estimation with conventional biometry in 2D ultrasound? A novel postpartum study. Commonly used formulae for fetal weight estimation, including combinations of several biometric parameters, lack accuracy despite efforts to improve them. This study aimed to investigate the limits of fetal weight estimation based on conventional biometric parameters on two-dimensional (2D) ultrasound by developing and evaluating new weight equations using postpartum

2011 Ultrasound in Obstetrics and Gynecology

215. Variants near CCNL1/LEKR1 and in ADCY5 and Fetal Growth Characteristics in Different Trimesters. Full Text available with Trip Pro

life onward in The Netherlands and Australia. Repeated fetal ultrasound examinations were performed to measure head circumference (HC), abdominal circumference (AC), femur length (FL), and estimated fetal weight (EFW). Analyses were based on a total group of 3909 subjects.The C-allele of rs900400 was associated in second trimester with smaller fetal HC and FL, and in third trimester with smaller HC, AC, FL, and EFW. For each C-allele, the combined effect estimate for EFW in third trimester (...) Variants near CCNL1/LEKR1 and in ADCY5 and Fetal Growth Characteristics in Different Trimesters. A recent genome-wide association study identified variants near CCNL1/LEKR1 (rs900400) and in ADCY5 (rs9883204) to be associated with birth weight. We examined the associations of these variants with fetal growth characteristics in different trimesters, with a main interest in the timing of the associations and the affected body proportions.We used data from two prospective cohort studies from fetal

2011 Journal of Clinical Endocrinology and Metabolism

216. The accuracy of sonographic weight estimation as a function of fetal sex. Full Text available with Trip Pro

The accuracy of sonographic weight estimation as a function of fetal sex. To determine whether the accuracy of sonographic fetal weight estimation is related to fetal sex.The accuracy of sonographic fetal weight estimation was compared between male and female fetuses using 3672 sonographic weight estimations performed within 3 days prior to delivery. Fetal weight was estimated using eight regression models that are based on different combinations of the following biometric parameters: abdominal (...) circumference (AC), femur diaphysis length (FL), biparietal diameter (BPD) and head circumference (HC).In seven out of the eight models tested, the presence of a male fetus was associated with a significantly lower systematic error compared with a female fetus (-0.2 to 2.1% vs. 1.3 to 6%, P<0.001). On multivariate analysis, fetal sex was independently associated with sonographic accuracy so that the likelihood of a weight estimation within 10% of birth weight was 30% higher for male fetuses compared

2011 Ultrasound in Obstetrics and Gynecology

217. Prenatal evaluation of the position of the fetal conus medullaris. Full Text available with Trip Pro

skin-covered spinal dysraphism.In 84.7% of the 300 cases, both operators were able to visualize the conus medullaris and the last vertebral body. Ninety-five percent limits of agreement for the intraobserver variability in measurement of conus distance were ± 1.9 mm. For the interobserver variability, they were - 3.7 and 2.5 mm. We found a linear relationship between conus distance and gestational age, biparietal diameter and abdominal circumference. The strongest relationship was observed (...) Prenatal evaluation of the position of the fetal conus medullaris. To determine the position of the fetal conus medullaris during pregnancy in relation to the last vertebral body and to examine its use in detecting skin-covered spinal dysraphism.This was a retrospective study involving 300 consecutive ultrasound examinations between 15 weeks of gestation and term. Two operators independently assessed images of the spine to determine whether the conus medullaris and the last vertebral body could

2011 Ultrasound in Obstetrics and Gynecology

218. Evaluation of Intra-Abdominal Fat in Patients With Type 2 Diabetes Using a Non-Invasive Method

Evaluation of Intra-Abdominal Fat in Patients With Type 2 Diabetes Using a Non-Invasive Method Evaluation of Intra-Abdominal Fat in Patients With Type 2 Diabetes Using a Non-Invasive Method - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Evaluation of Intra-Abdominal Fat in Patients With Type 2 Diabetes Using a Non-Invasive Method The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01283113 Recruitment Status : Completed First Posted : January 25, 2011 Last Update Posted : March 1, 2017 Sponsor: Joslin

2011 Clinical Trials

219. Cerebral palsy in under 25s: assessment and management

to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 24 of 46non-specific back pain headache non-specific abdominal pain dental pain dysmenorrhea. Assessment Assessment 1.13.4 T ake into account that parents and familiar carers have a key role in recognising and assessing pain, discomfort and distress in children and young people with cerebral palsy. 1.13.5 When assessing pain in children and young people with cerebral palsy: recognise that assessing the presence

2017 National Institute for Health and Clinical Excellence - Clinical Guidelines

220. Determination of Gestational Age by Ultrasound

and 14th weeks, crown–rump length and biparietal diameter are similar in accuracy. It is recommended that crown-rump length be used up to 84 mm, and the biparietal diameter be used for measurements > 84 mm (II-1 A). 4 If a second- or third-trimester scan is used to determine gestational age, a combination of multiple biometric parameters (biparietal diameter, head circumference, abdominal circumference, and femur length) should be used to determine gestational age, rather than a single parameter (II-1 (...) for aneuploidy. A national algorithm for the assignment of gestational age may reduce practice variations across Canada for clinicians and researchers. Potential harms include the possible reassignment of dates when significant fetal pathology (such as fetal growth restriction or macrosomia) result in a discrepancy between ultrasound biometric and clinical gestational age. Such reassignment may lead to the omission of appropriate—or the performance of inappropriate—fetal interventions. Summary Statements 1

2019 Society of Obstetricians and Gynaecologists of Canada

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