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Femoral Neck Stress Fracture

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161. Hip Fractures

from which of the following substances is most likely to increase a patient’s heat input? Alcohol Cannabis Cocaine Phencyclidine NEWS & VIDEOS Some Lose Independence After Surgical Tx of Femoral Neck Fx WEDNESDAY, March 6, 2019 (HealthDay News) -- A considerable proportion of older patients with femoral neck fracture are institutionalized or require walking aids 12 months after surgical treatment... 3D Model Musculoskeletal Connective Tissues Video Prone Quadriceps Stretch 1. Lie on stomach. 2 (...) , particularly those with osteoporosis, and usually result from ground level falls. Diagnosis is by x-rays or, if needed, MRI. Treatment is usually with open reduction with internal fixation or sometimes hemiarthroplasty or total hip arthroplasty. Most hip fractures result from falls, but in the elderly, seemingly minimal force (eg, rolling over in bed, getting up from a chair, walking) can result in fracture, usually because has weakened the bone. Fracture locations include Femoral head Femoral neck

2013 Merck Manual (19th Edition)

162. Cemented versus non-cemented hemiarthroplasty of the hip as a treatment for a displaced femoral neck fracture: design of a randomised controlled trial. (PubMed)

Cemented versus non-cemented hemiarthroplasty of the hip as a treatment for a displaced femoral neck fracture: design of a randomised controlled trial. A discussion is ongoing whether displaced femoral neck fractures in elderly patients should be treated with a non-cemented or a cemented hemiarthroplasty. A recent Cochrane analysis stresses the importance of further research into the relative merits of these techniques. We hypothesise that non-cemented hemiarthroplasty will result in at least (...) the same technical-functional outcome and complication rate, with a shorter operation time.A randomised controlled multicentre trial will be performed.The study population consists of 200 patients of 70 years and older. Patients with a displaced femoral neck fracture will be allocated randomly to have a cemented or a non-cemented hemiarthroplasty. Data will be collected preoperatively, immediately postoperatively, and 6 weeks, 3 months and 1 year postoperatively.The main outcome measures of this study

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2009 BMC musculoskeletal disorders

163. Femoral Neck Trabecular Bone: Loss with Ageing and Role in Preventing Fracture. (PubMed)

or buckling resistance was increased by the trabecular bone supporting the most stressed cortical sector in each femoral neck. We repeated these measurements and calculations in an age- and sex-matched series of femoral necks donated by women who had suffered intracapsular hip fracture and controls, using histological measurements of cortical thickness to improve accuracy. With normal aging, trabecular BMD declined asymmetrically, fastest in the supero-lateral one-half (in antero-posterior projection (...) Femoral Neck Trabecular Bone: Loss with Ageing and Role in Preventing Fracture. Hip fracture risk rises 100- to 1000-fold over six decades of age, but only a minor part of this increase is explained by declining BMD. A potentially independent cause of fragility is cortical thinning predisposing to local crushing, in which bone tissue's material disintegrates at the microscopic level when compressed beyond its capacity to maintain integrity. Elastic instability or buckling of a much thinned

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2009 Journal of Bone and Mineral Research

164. Spontaneous bilateral femoral neck fractures associated with a low serum level of vitamin D in a young adult. (PubMed)

Spontaneous bilateral femoral neck fractures associated with a low serum level of vitamin D in a young adult. Bilateral femoral neck fracture is an extremely rare injury in young adults. We report a young adult with bilateral femoral neck fracture after minimal stress. The current case did not demonstrate any abnormality on laboratory data, except for a low serum level of vitamin D(3). Although, in our case, the patient underwent bilateral femoral head arthroplasty, early diagnosis could have (...) been helpful to avoid further displacement of the fracture and surgical treatment.

2009 Journal of Arthroplasty

165. Evaluate the Effect of Bone Marrow Derived Cd133+ Cells in Patient With Osteonecrosis of Femoral Head

Description: A vascular necrosis of femoral head is a debilitating disease resulting from interruption of blood supply to the bone. This pathologic process results in the death of marrow and osteocytes and, in its final stage, femoral head collapse. The most widespread treatment in the early stage of this disease is core decompression. This surgical procedure involves drilling into the femoral neck through the necrotic area, which reduces pressure within the bone and allows more blood vessels to form (...) osteonecrosis, primarily based on diagnosis by MRI. Flattening of the femur head (UPenn Stage IV) or articular cartilage collapse at the time of core decompression surgery. Septic arthritis; stress fracture, or non-osteonecrosis metabolic bone diseases (e.g., Paget's disease of bone, osteogenesis imperfecta, primary hyperparathyroidism, fibrous dysplasia [monostotic, polyostotic McCune-Albright syndrome] and osteopetrosis). Any active bisphosphonate treatment or any history of intravenous (IV) treatment HIV

2010 Clinical Trials

166. Overview of sport-related injuries

that requires swift diagnosis and treatment to prevent irreversible spinal cord injury and long-term disability. Acute spinal cord injury should be suspected in any patient following trauma, particularly when the trauma is to the head or neck and when the patient is unresponsive due to hypotension and has respiratory compromise. Can occur as a result of spine trauma, vertebral compression fracture, intervertebral disc herniation, primary or metastatic spinal tumour, or infection. The resulting spinal cord (...) subluxation or dislocation, labral tears, chondral injuries, and fractures. Chronic/overuse causes include bursitis, tendonitis, athletic pubalgia (sports hernia), osteitis pubis, snapping hip syndrome, and stress fractures. Holderbaum D, Haqqi TM, Moskowitz RW. Genetics and osteoarthritis: exposing the iceberg. Arthritis Rheum. 1999;42:397-405. http://onlinelibrary.wiley.com/doi/10.1002/1529-0131%28199904%2942:3%3C397::AID-ANR1%3E3.0.CO;2-X/pdf http://www.ncbi.nlm.nih.gov/pubmed/10088759?tool

2018 BMJ Best Practice

167. Overview of musculoskeletal pain

/jama/fullarticle/197628 http://www.ncbi.nlm.nih.gov/pubmed/14612481?tool=bestpractice.com Related conditions Condition Description Chronic fibrosing condition characterised by insidious, progressive, and severe restriction of both active and passive shoulder range of motion. Many patients experience shoulder pain, but shoulder pain is not an essential component of adhesive capsulitis. Although other fractures around and including the ankle can occur (such as distal tibial plafond fractures (...) ), the term 'ankle fracture' generally refers to the medial, lateral, or posterior malleolus. An inflammatory arthritis predominantly affecting the sacroiliac joints and axial spine. Inflammatory back pain is the hallmark clinical feature. This is defined as back pain/stiffness, which is worse in the morning and improves with exercise. Injury typified by sudden, painful, audible 'pop' noise. Patient typically presents with inability to return to activity, joint instability, and rapid development

2018 BMJ Best Practice

168. Menopause

. Osteoporosis Osteoporosis is a condition of the skeleton in which bone strength is compromised, predisposing the woman to an increased risk of fracture (NOS, 2017). In the UK, 1-in-3 women and 1-in-12 men over the age of 50 will suffer a fragility fracture due to osteoporosis (Torgeson et al., 2001). The most common fracture sites are the femoral neck, forearm and spine (NICE, 2017c). As oestrogen levels decline, the risk of osteoporosis increases. The disease leads to weakness in the skeleton which can (...) continue for many years afterwards. Psychological problems It is unclear why psychological symptoms occur at the menopause, and these may well have little to do with hormonal fluctuations. Life stresses at this age, as well as past problems, are an obvious causative factor. Many women do not realise that the following symptoms are very normal at this stage of life and fear they may be on the verge of a breakdown: • loss of confidence • depressed mood • irritability • forgetfulness • difficulty

2018 Royal College of Nursing

170. AIM Clinical Appropriateness Guidelines for Joint Surgery

and placement of a prosthesis anchored to the bone. Numerous implants composed of various biomaterials have been approved by the U.S. Food and Drug Administration (FDA) for use in hip arthroplasty. The goal of the procedure is long-term pain relief and restoration of function. Degenerative joint disease, or osteoarthritis, is the most common condition leading to the need for THA. Other conditions that may also cause significant hip joint damage include neoplasm, femoral fracture, avascular necrosis (...) Surgery 21 3. Department of Veterans Affairs DoDN-SMoHaKOWG, VA/DoD clinical practice guideline for the non-surgical management of hip and knee osteoarthritis., (2014) Washington DC, 126. 4. Goyal N, Chen AF, Padgett SE, et al. Otto Aufranc Award: A Multicenter, Randomized Study of Outpatient versus Inpatient Total Hip Arthroplasty. Clinical orthopaedics and related research. 2017;475(2):364-72. 5. Hagel A, Siekmann H, Delank KS. Periprosthetic femoral fracture - an interdisciplinary challenge. Dtsch

2019 AIM Specialty Health

171. Extremity imaging

scenario: ? Evaluation of acute shoulder pain following initial radiographs when imaging is required to establish the diagnosis and the patient is a candidate for corticosteroid or anesthetic injection IMAGING STUDY - MRI upper extremity joint Imaging of the Extremities Copyright © 2019. AIM Specialty Health. All Rights Reserved. 16 - CT may be utilized when MRI contraindicated Trauma Fracture Note: Sites at high risk for fracture include femoral neck/proximal femur, tibia (anterior/lateral), great toe (...) to persons of all ages. See the Coding section for a list of modalities included in these guidelines. Technology Considerations In general, conventional radiographs should be obtained prior to advanced imaging. Computed tomography (CT) is often the preferred modality for evaluation of displaced fractures and subluxations, whereas stress fractures and some incomplete and non-displaced fractures may be better imaged with magnetic resonance imaging (MRI) or radionuclide bone scintigraphy. Tendons

2019 AIM Specialty Health

173. Management of Non-neurogenic Male LUTS

and fracture with the initiation of a prostate-selective alpha antagonist: a population based cohort study. BMJ, 2015. 351: h5398. 145. Chang, D.F., et al. Intraoperative floppy iris syndrome associated with tamsulosin. J Cataract Refract Surg, 2005. 31: 664. 146. Chatziralli, I.P., et al. Risk factors for intraoperative floppy iris syndrome: a meta-analysis. Ophthalmology, 2011. 118: 730. 147. van Dijk, M.M., et al. Effects of alpha(1)-adrenoceptor antagonists on male sexual function. Drugs, 2006. 66: 287

2019 European Association of Urology

174. Chronic Pelvic Pain

. Pitfalls of the medical paradigm in chronic pelvic pain. Baillieres Best Pract Res Clin Obstet Gynaecol, 2000. 14: 525. 82. Sharpe, M., et al. "Unexplained" somatic symptoms, functional syndromes, and somatization: do we need a paradigm shift? Ann Intern Med, 2001. 134: 926. 83. Malykhina, A.P. Neural mechanisms of pelvic organ cross-sensitization. Neuroscience, 2007. 149: 660. 84. Sanford, M.T., et al. The role of environmental stress on lower urinary tract symptoms. Curr Opin Urol, 2017. 27: 268. 85 (...) subtypes of chronic pelvic pain and how subtypes differ in health status and trauma history. Am J Obstet Gynecol, 2006. 195: 554. 90. Meltzer-Brody, S., et al. Trauma and posttraumatic stress disorder in women with chronic pelvic pain. Obstet Gynecol, 2007. 109: 902. 91. Iglesias-Rios, L., et al. Depression and Posttraumatic Stress Disorder Among Women with Vulvodynia: Evidence from the Population-Based Woman to Woman Health Study. Journal of Women's Health (15409996), 2015. 24: 557. 92. Anderson, A.B

2019 European Association of Urology

175. Pharmacological Management of Osteoporosis in Postmenopausal Women

-risk thresholds for other age groups ( ). In the United States, pharmacological therapy is recommended for postmenopausal women with hip or vertebral fractures; those with T-scores of −2.5 or less in the femoral neck, total hip, or lumbar spine; and those with T-scores of −1 to −2.5 and a 10-year probability of ≥20% for major osteoporotic fractures or ≥3% for hip fractures based on the US-adapted FRAX tool ( ). BMD T-score is defined as the number of SDs from the mean BMD of white females age 20 (...) to 29 years in the Third National Health and Nutrition Examination Survey database. For the treatment of osteoporosis, only lumbar spine, total hip, and femoral neck BMD T-scores are usually considered. Data suggest that a recent fracture (within the past 2 years) is a better predictor of imminent fracture risk ( i.e. , risk of fracture within the next 2 years) than is a distant fracture history (>5 years ago) ( , ). This is true for recent vertebral fractures ( , ) as well as nonvertebral fractures

2019 The Endocrine Society

177. Treatment for Acute Pain: An Evidence Map (Draft)

with Fractures 25 Visceral Pain 27 Renal Colic 27 Orofacial Pain 30 Dental Pain 30 Episodic Pain Conditions 30 Acute Migraine 30 Sickle Cell Crisis 37 Discussion 39 Limitations 41 Tables Table 1. Eligible Systematic Reviews and Relevant Studies: All Acute Pain Conditions 10 Table 2. Current Guidelines: Treatment for Postoperative Pain 12 Table 3. Current Guidelines: Treatments for Acute Back Pain 15 Table 4. Current Guidelines: Treatments for Acute Neck Pain 21 Table 5. Current Guidelines: Treatments (...) in Systematic Reviews: Acute Neck Pain 24 Figure 6. Comparisons addressed in Systematic Reviews and New Trials: Fractures 26 Figure 7. Comparisons addressed in Systematic Reviews and New Trials: Renal Colic 29 vii Figure 8. Comparisons addressed in Systematic Reviews: Acute migraine in adults-placebo controlled RCTs in adults 33 Figure 9. Comparisons addressed in Systematic Reviews and New Trials: Acute migraine in adults-active controlled 34 Figure 10. Comparisons addressed in Systematic Reviews and New

2019 Effective Health Care Program (AHRQ)

178. Management of Osteoporosis in Survivors of Adult Cancers With Nonmetastatic Disease

. Clinicians should actively encourage patients to stop smoking and to limit alcohol consumption, as smoking and alcohol consumption are risk factors for osteoporosis (Type: evidence based, benefits outweigh harms; Evidence quality: low; Strength of recommendation: moderate). Pharmacologic Intervention Recommendation 3.4. For patients with nonmetastatic cancer with osteoporosis (T scores of −2.5 or less in the femoral neck, total hip, or lumbar spine) or who are at increased risk of osteoporotic fractures (...) with radiation therapy can also have a direct effect on bone in the treated field which leads to bone atrophy. It can also indirectly effect bone through vascular changes. Insufficiency fractures are a common complication after radiation therapy and generally affect bones that are under the most physiologic stress —for example, pelvic or rib fractures with pelvic or chest irradiation, respectively. A variety of physical, metabolic, and psychosocial changes in patients with cancer, such as malnourishment due

2019 American Society of Clinical Oncology Guidelines

179. Adalimumab (Hefiya) - Juvenile Rheumatoid Arthritis, Hidradenitis Suppurativa, Psoriasis, Ankylosing Spondylitis, Uveitis

substance is stable under the recommended conditions. Supporting information on accelerated and stress stability data and data from thermal freeze/thaw cycles as well as photo-stability data have been provided. Comparability exercise for Active Substance The development activities include the initial development of the AS manufacturing process, the following scale up and transfer from the pilot scale to the manufacturing scale at different plants and lines. Comparability was demonstrated in data between (...) , and additional sampling demonstrate that the manufacturing process is reliable and delivers product of consistent quality. Hold and process times have been defined and are supported by adequate microbiological and physicochemical hold time studies. Adequacy of the established shipment conditions was verified by a transport validation study which included four shipments of Hefiya FP PFS from Mylan to Cook using qualified shipment containers and shippers. A potential impact of mechanical stress on quality

2018 European Medicines Agency - EPARs

180. Adalimumab (Halimatoz) - Juvenile Rheumatoid Arthritis, Psoriatic Arthritis, Rheumatoid Arthritis, Hidradenitis Suppurativa, Psoriasis, Ankylosing Spondylitis, Uveitis

-term stability data. The results demonstrate that Halimatoz active substance is stable under the recommended conditions. Supporting information on accelerated and stress stability data and data from thermal freeze/thaw cycles as well as photo-stability data have been provided. Comparability exercise for Active Substance The development activities include the initial development of the AS manufacturing process, the following scale up and transfer from the pilot scale to the manufacturing scale (...) FP PFS from Mylan to Cook using qualified shipment containers and shippers. A potential impact of mechanical stress on quality and integrity of Halimatoz bulk PFS was sufficiently addressed by a second transport validation study. A continued process verification program is in place to ensure process consistency throughout the life-cycle. To validate the assembly and packaging process three process runs were performed at Cook for each the NSD and AI. The presented AQL, IPC, functional testing

2018 European Medicines Agency - EPARs

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