How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

150 results for

Female Pseudohermaphroditism

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Idiopathic female pseudohermaphroditism with urethral duplication and female hypospadias (PubMed)

Idiopathic female pseudohermaphroditism with urethral duplication and female hypospadias Female hypospadias is a rare anomaly of the female urethra where it opens on the anterior vaginal wall anywhere between the introitus and the fornix. It is often associated with other genitourinary anomalies such as Cloacal malformation, female pseudohermaphroditism, nonneurogenic neurogenic bladder and urethral duplication. Idiopathic female pseudohermaphroditism is extremely rare, and most cases occur (...) secondary to adrenogenital syndrome or maternal androgen exposure. We report a unique case of a 1-year and 4-month-old girl who presented with ambiguous genitalia and renal failure secondary to a non-neurogenic neurogenic bladder. On further evaluation, she was found to have urethral duplication with a hypospadiac female urethra. She initially underwent a vesicostomy and was further planned to undergo an appendicular Mitrofanoff at an older age. The mainstay of treatment in these cases includes relief

Full Text available with Trip Pro

2016 BMJ case reports

2. Female Pseudohermaphroditism

Female Pseudohermaphroditism Female Pseudohermaphroditism Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Female Pseudohermaphroditism (...) Female Pseudohermaphroditism Aka: Female Pseudohermaphroditism From Related Chapters II. Causes Deficiencies of enzyme activity 3B Hydroxysteroid dehydrogenase - Type 2 : 1p13.1 21-Hydroxylase : 6p21.3 11B-Hydroxylase - Type 1 8q21 Deficiencies of placental or germ-line aromatase Maternal Virilizing luteoma Ingestion of androgens, synthetic s Eponymic Syndromes Fraser syndrome VACTERL association III. Signs Internal genitalia are female External genitalia are masculinized Images: Related links

2018 FP Notebook

3. Congenital adrenal hyperplasia and vanishing testis: rare case of male pseudohermaphroditism (PubMed)

Congenital adrenal hyperplasia and vanishing testis: rare case of male pseudohermaphroditism Congenital adrenal hyperplasia (CAH) and vanishing testes are uncommon diseases that can result from hormonal and mechanical factors. Classic CAH is determined by ambiguous genitalia and increase in amount of 17-Hydroxyprogesterone. Simultaneous occurrence of CAH and vanishing testes is a rare condition.A 22-year-old boy, known case of CAH who was diagnosed as female pseudohermaphroditism due

Full Text available with Trip Pro

2016 International Journal of Reproductive Biomedicine

4. Female Pseudohermaphroditism

Female Pseudohermaphroditism Female Pseudohermaphroditism Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Female Pseudohermaphroditism (...) Female Pseudohermaphroditism Aka: Female Pseudohermaphroditism From Related Chapters II. Causes Deficiencies of enzyme activity 3B Hydroxysteroid dehydrogenase - Type 2 : 1p13.1 21-Hydroxylase : 6p21.3 11B-Hydroxylase - Type 1 8q21 Deficiencies of placental or germ-line aromatase Maternal Virilizing luteoma Ingestion of androgens, synthetic s Eponymic Syndromes Fraser syndrome VACTERL association III. Signs Internal genitalia are female External genitalia are masculinized Images: Related links

2015 FP Notebook

5. Female Pseudohermaphroditism with Adrenocortical Failure in Identical Twins (PubMed)

Female Pseudohermaphroditism with Adrenocortical Failure in Identical Twins 13149215 2003 05 01 2018 12 01 0003-9888 29 144 1954 Apr Archives of disease in childhood Arch. Dis. Child. Female pseudohermaphroditism with adrenocortical failure in identical twins. 132-5 WOLFF S S eng Journal Article England Arch Dis Child 0372434 0003-9888 OM 46, XX Disorders of Sex Development Adrenal Cortex Adrenal Cortex Diseases Disease Diseases in Twins Disorders of Sex Development Humans Twins Twins

Full Text available with Trip Pro

1954 Archives of Disease in Childhood

6. Female Pseudohermaphroditism Treated with Oral Cortisone (PubMed)

Female Pseudohermaphroditism Treated with Oral Cortisone 13199746 2003 05 01 2018 12 01 0008-4409 71 4 1954 Oct Canadian Medical Association journal Can Med Assoc J Female pseudohermaphroditism treated with oral cortisone. 385-6 PATTEE J C JC WYSE D M DM HOWARD R P RP eng Journal Article Canada Can Med Assoc J 0414110 0008-4409 V27W9254FZ Cortisone OM 46, XX Disorders of Sex Development Cortisone therapeutic use Disorders of Sex Development 5527:11391:126:217 CORTISONE/therapeutic use

Full Text available with Trip Pro

1954 Canadian Medical Association Journal

7. Successful Pregnancy in a Female Pseudohermaphrodite (PubMed)

Successful Pregnancy in a Female Pseudohermaphrodite 13774331 1998 11 01 2018 12 02 0007-1447 1 5231 1961 Apr 08 British medical journal Br Med J Successful pregnancy in a female pseudohermaphrodite. 1005-6 SWYER G I GI BONHAM D G DG eng Case Reports Journal Article England Br Med J 0372673 0007-1447 OM Adrenal Hyperplasia, Congenital Adrenogenital Syndrome Genitalia Medical Records Pregnancy ADRENOGENITAL SYNDROME/case reports PREGNANCY 1961 4 8 1961 4 8 0 1 1961 4 8 0 0 ppublish 13774331

Full Text available with Trip Pro

1961 British medical journal

8. Pseudohermaphroditism due to XY gonadal absence syndrome. (PubMed)

Pseudohermaphroditism due to XY gonadal absence syndrome. A 21-year-old phenotypic female with a 46,XY chromosome complement and gonadal absence was studied. Basal levels of plasma immunoreactive luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone, and oestradiol were measured. Pituitary sensitivity and reserve was evaluated by the exogenous administration of synthetic luteinizing hormone-releasing hormone. The episodic release of gonadotrophins was assessed by measuring

Full Text available with Trip Pro

1976 Journal of Medical Genetics

9. Male pseudohermaphroditism presumably due to target organ unresponsiveness to androgens. Deficient 5alpha-dihydrotestosterone binding in cultured skin fibroblasts. (PubMed)

Male pseudohermaphroditism presumably due to target organ unresponsiveness to androgens. Deficient 5alpha-dihydrotestosterone binding in cultured skin fibroblasts. Maximum specific 5alpha-dihydrotestosterone (DHT) binding activity (Bmax) had been measured in intact confluent monolayers representing fibroblast strains derived form nongenital and genital (labium majus) skin of normal individuals and of 11 patients fulfilling the clinicogenetic criteria of complete testicular feminization (TF (...) ). Nine labium majus strains from adult females had a mean Bmax value three times greater than that of seven nongenital strains from adult females (33 vs. 11 fmol/mg cell protein). The Bmax results for 13 adult nongenital strains varied from 5.6 to 23.3 fmol/mg protein; the values for males and females had very similar means and ranges. The variation could not be correlated with the chronologic age of adult skin explant donors or with the in vitro age (mean population doubling level) of the cultures

Full Text available with Trip Pro

1976 Journal of Clinical Investigation

10. Male pseudohermaphroditism: diagnosis in cell culture. (PubMed)

Male pseudohermaphroditism: diagnosis in cell culture. Testicular feminization is a classic form of complete male pseudohermaphroditism. The individuals have a normal XY karyotype but unambiguously female external genitalia. They have congenital complete insensitivity to androgen due to an X-linked mutation. In four patients (from tow families with several affected members) with the typical phenotype of testicular feminization, a severe deficit of specific androgen-binding activity was detected (...) in cultured fibroblasts from labium majus skin. Measurement of this activity in genital skin fibroblasts improves the differential diagnosis in patients with complete or imcomplete male pseudohermaphroditism before puberty.

Full Text available with Trip Pro

1977 Canadian Medical Association Journal

11. Male pseudohermaphroditism due to 17α-hydroxylase deficiency (PubMed)

the concept of femaleness during ontogeny unless counteracted by male factors. Diagnosis of other adrenocortical enzymatic deficiencies is excluded by the steroidal studies. The clinical response to testosterone excludes testicular feminization. Deficiency of 17-hydroxylation must be added to the cause of male pseudohermaphroditism. (...) Male pseudohermaphroditism due to 17α-hydroxylase deficiency This is the first report of a male with 17alpha-hydroxylase deficiency resulting in male pseudohermaphroditism, ambiguous external genitalia, absence of male secondary sexual characteristics, and gynecomastia at puberty. Diagnosis was based on extensive studies of steroid metabolism including the following: low urinary excretion of 17-ketosteroids and 17-hydroxycorticoids which did not increase after ACTH; no response of very low

Full Text available with Trip Pro

1970 Journal of Clinical Investigation

12. Estradiol and Testosterone Secretion by Human, Simian, and Canine Testes, in Males with Hypogonadism and in Male Pseudohermaphrodites with the Feminizing Testes Syndrome (PubMed)

Estradiol and Testosterone Secretion by Human, Simian, and Canine Testes, in Males with Hypogonadism and in Male Pseudohermaphrodites with the Feminizing Testes Syndrome The role of the human testis in the production of 17beta-estradiol (E(2)) was investigated by determining the concentration of E(2) and testosterone in peripheral and spermatic vein plasma samples. Specimens were obtained from eight normal men, three men with hypogonadism, and two patients with the incomplete form (...) for charcoaladsorbed pooled male plasma. Pooled male and pooled female control plasmas averaged 17+/-0.71 pg/ml and 95+/-6.9 pg/ml, respectively; individual adult male specimens ranged between 8 and 28 with a mean of 18+/-1.4 pg/ml. In the eight normal men, the mean peripheral vein E(2) concentration was 20+/-1.6 pg/ml, while the spermatic vein concentration was 50 times as great, 1049+/-57 pg/ml. All three patients with testicular abnormalities had low spermatic vein E(2) concentrations (160, 280, and 416 pg/ml

Full Text available with Trip Pro

1972 Journal of Clinical Investigation

13. Studies on the pathogenesis of the pseudohermaphroditism in the mouse with testicular feminization (PubMed)

, the effect of the administration of dihydrotestosterone to pregnant animals was studied in male, female, and Tfm offspring. Whereas normal and carrier female littermates demonstrated striking virilization of the internal genital tract after such treatment, there was no sign of virilization in the Tfm animals. This finding provides direct experimental evidence in support of the view that male pseudohermaphroditism in testicular feminization is the result of resistance to androgen action during androgen (...) Studies on the pathogenesis of the pseudohermaphroditism in the mouse with testicular feminization The pathogenesis of the male pseudohermaphroditism in the mouse with X-linked testicular feminization (Tfm) has been investigated by comparing testosterone formation, the effects of androgen administration, and the metabolism of testosterone-1,2-(3)H in normal mice and Tfm mice of varying ages. First, it was established that the adult Tfm animal, in contrast to the human with testicular

Full Text available with Trip Pro

1972 Journal of Clinical Investigation

14. Male Pseudohermaphroditism in a Child with Down's Syndrome (PubMed)

Male Pseudohermaphroditism in a Child with Down's Syndrome 4268392 1973 08 31 2018 11 13 0022-2593 10 2 1973 Jun Journal of medical genetics J. Med. Genet. Male pseudohermaphroditism in a child with Down's syndrome. 189-92 Golbus M S MS Beauchamp C J CJ Conte F A FA eng Case Reports Journal Article England J Med Genet 2985087R 0022-2593 0 Antiemetics 0 Thyroid Hormones IM Adult Aneuploidy Antiemetics therapeutic use Child, Preschool Disorders of Sex Development complications Down Syndrome (...) complications genetics Female Goiter drug therapy Growth Disorders genetics Humans Infant Infant, Newborn Karyotyping Nausea drug therapy Pregnancy Pregnancy Complications drug therapy Sex Chromosome Aberrations Thyroid Hormones therapeutic use 1973 6 1 1973 6 1 0 1 1973 6 1 0 0 ppublish 4268392 PMC1013016 J Med Genet. 1967 Dec;4(4):258-9 6082902 Am J Clin Pathol. 1971 Feb;55(2):232-6 5100209 J Clin Endocrinol Metab. 1971 May;32(5):611-8 4252810 Nat New Biol. 1971 Jul 7;232(27):31-2 4105244

Full Text available with Trip Pro

1973 Journal of Medical Genetics

15. Non-adrenal Female Pseudo-hermaphroditism Associated with Hormone Administration in Pregnancy (PubMed)

Non-adrenal Female Pseudo-hermaphroditism Associated with Hormone Administration in Pregnancy 13645665 2000 07 01 2018 12 01 0035-9157 52 4 1959 Apr Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Non-adrenal female pseudohermaphroditism associated with hormone administration in pregnancy. 300-1 JOLLY H H eng Journal Article England Proc R Soc Med 7505890 0035-9157 0 Hormones OM 46, XX Disorders of Sex Development Disorders of Sex Development Female Hormones pharmacology Humans

Full Text available with Trip Pro

1959 Proceedings of the Royal Society of Medicine

16. Hormone replacement therapy (male-to-female)

Hormone replacement therapy (male-to-female) Transgender hormone therapy (male-to-female) - Wikipedia Transgender hormone therapy (male-to-female) From Wikipedia, the free encyclopedia (Redirected from ) Hormone replacement therapy Part of on and medicine Sex reassignment issues Discrimination Toilets Violence Society and culture Characters Events Theory and concepts Australia Canada India United Kingdom United States See also Transgender hormone therapy of the male-to-female ( MTF ) type, also (...) of testosterone levels by parenteral estradiol. Testosterone levels in relation to estradiol levels (and corresponding estradiol dosages) during therapy with oral estradiol alone or in combination with an antiandrogen in transgender women. The dashed purple line is the upper limit for the female/castrate range (~50 ng/dL) and the dashed grey line is the testosterone level in a comparison group of post-operative transgender women (21.7 pg/mL). are the major sex hormones in women, and are responsible

2012 Wikipedia

18. Male Hypogonadism

, tumour, torsion, inflammation, iatrogenic, surgical removal Secondary testicular dysfunction Medication, drugs, toxins, systemic diseases, varicocele (Idiopathic) testicular atrophy/testicular dysgenesis Male infertility (idiopathic or specific causes) Congenital anorchia (bilateral in 1 in 20,000 males, unilateral four times as often) Intra-uterine torsion is the most probable cause 46,XY disorders of sexual development (DSD) (formerly male pseudohermaphroditism) Disturbed testosterone synthesis due

2019 European Association of Urology

19. Childhood Cancer Genomics (PDQ®): Health Professional Version

cases and is associated with older age (median, approximately 10 years), presenting WBC of less than 50 × 10 9 /L, a slight female preponderance, and high end-induction MRD.[ - ] The United Kingdom (UK)–ALL clinical trials group initially reported that the presence of iAMP21 conferred a poor prognosis in patients treated in the MRC ALL 97/99 trial (5-year EFS, 29%).[ ] In their subsequent trial ( ), patients with iAMP21 were assigned to a more intensive chemotherapy regimen and had a markedly better

Full Text available with Trip Pro

2018 PDQ - NCI's Comprehensive Cancer Database

20. Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®): Health Professional Version

The incidence of Wilms tumor is 7.1 cases per 1 million children younger than 15 years. Approximately 650 cases of Wilms tumor are diagnosed in the United States each year. The incidence is substantially lower in Asians. The male to female ratio in unilateral cases of Wilms tumor is 0.92 to 1.00, but in bilateral cases, it is 0.60 to 1.00. The mean age at diagnosis is 44 months in unilateral cases and 31 months in bilateral cases of Wilms tumor.[ , ] About 10% of children with Wilms tumor have an associated (...) mutations produce genetic syndromes that are characterized by nephropathy, 46XY disorder of sex development, and varying risks of Wilms tumor.[ , ] Denys-Drash and Frasier syndromes. Denys-Drash syndrome is characterized by nephrotic syndrome caused by diffuse mesangial sclerosis, XY pseudohermaphroditism, and increased risk of Wilms tumor (>90%). Frasier syndrome is characterized by progressive nephropathy caused by focal segmental glomerulosclerosis, gonadoblastoma, and XY pseudohermaphroditism. WT1

2017 PDQ - NCI's Comprehensive Cancer Database

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>